p53 ancestry: gazing through an evolutionary lens

Wnt/β-Catenin Signaling in Development and Disease

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Blinded by the Light: The Growing Complexity of p53

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p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

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The Draft Genome of <i>Ciona intestinalis</i> : Insights into Chordate and Vertebrate Origins

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Modes of p53 regulation.

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Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

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DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

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DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2

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Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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The IARC TP53 database: new online mutation analysis and recommendations to users

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The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

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When mutants gain new powers: News from the mutant p53 field

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Hedgehog Signaling in Development and Cancer

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Gene Regulatory Networks in the Evolution and Development of the Heart

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

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p63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia

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p53 isoforms can regulate p53 transcriptional activity

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A Mutant-p53/Smad Complex Opposes p63 to Empower TGFβ-Induced Metastasis

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Modeling the Therapeutic Efficacy of p53 Restoration in Tumors

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tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

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p63 protects the female germ line during meiotic arrest

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p53 Regulates Hematopoietic Stem Cell Quiescence

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Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

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Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance

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p53 regulates maternal reproduction through LIF

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TAp73 knockout shows genomic instability with infertility and tumor suppressor functionsPreprint

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p53 suppresses the self-renewal of adult neural stem cells

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Genomic Evolution of Hox Gene Clusters

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Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling

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Drosophila melanogaster MNK/Chk2 and p53 Regulate Multiple DNA Repair and Apoptotic Pathways following DNA Damage

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Stimulation of autophagy by the p53 target gene Sestrin2

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Mitochondrial Regulation of Cell Cycle Progression during Development as Revealed by the tenured Mutation in Drosophila

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p53 in recombination and repair

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Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2Preprint

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p53 alterations in human cancer: more questions than answers

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Drosophila p53 preserves genomic stability by regulating cell death

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Recent advances in p53 research: an interdisciplinary perspective

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Casting a Genetic Light on the Evolution of Eyes

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The effects of p53 on whole organism longevity are mediated by autophagy

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Prognostic and predictive value of p53 and p21 in breast cancer

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The nucleotide excision repair pathway is required for UV-C-induced apoptosis in Caenorhabditis elegans

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Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

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p53 directs focused genomic responses in Drosophila

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The p53 Tumor Suppressor-Like Protein nvp63 Mediates Selective Germ Cell Death in the Sea Anemone Nematostella vectensis

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In vivo p53 function is indispensable for DNA damage‐induced apoptotic signaling in Drosophila

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Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network

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Early diversification and complex evolutionary history of the p53 tumor suppressor gene family

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Programmed cell death of primordial germ cells inDrosophilais regulated by p53 and the Outsiders monocarboxylate transporter

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p53 family in development

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p73 and p63 protein stability: the way to regulate function?

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Ehp53, an Entamoeba histolytica protein, ancestor of the mammalian tumour suppressor p53

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One INK4 gene and no ARF at the Fugu equivalent of the human INK4A/ARF/INK4B tumour suppressor locus

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Reassessing the role of p53 in cancer and ageing from an evolutionary perspective

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Master regulatory genes; telling them what to do

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Influence of p53 and genetic background on prenatal oogenesis and oocyte attrition in mice

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Biochemical and Functional Evidence of p53 Homology Is Inconsistent with Molecular Phylogenetics for Distant Sequences

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The p53 Pathway: Origins, Inactivation in Cancer, and Emerging Therapeutic Approaches

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The p53 orchestra: Mdm2 and Mdmx set the tone

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Evolutionary Determinants of Cancer

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p53 at a glance

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p53-family proteins and their regulators: hubs and spokes in tumor suppression

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p53 genes function to restrain mobile elementsPreprint

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p53 Isoforms: Key Regulators of the Cell Fate DecisionPreprint

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Current strategies to target p53 in cancer

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Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D2concept

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How mutations shape p53 interactions with the genome to promote tumorigenesis and drug resistance

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Increased Oxidative Metabolism in the Li–Fraumeni Syndrome

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A Polymorphic p53 Response Element in KIT Ligand Influences Cancer Risk and Has Undergone Natural Selection

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Ribosomal protein–Mdm2–p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation

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P53 and Sirt1: Routes of metabolism and genome stability

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Meiotic Recombination Provokes Functional Activation of the p53 Regulatory Network

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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?Preprint

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The Multifunctional Sorting Protein PACS-2 Regulates SIRT1-Mediated Deacetylation of p53 to Modulate p21-Dependent Cell-Cycle Arrest

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Intrinsically disordered regions of p53 family are highly diversified in evolution

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RAD51: Beyond the break

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Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

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Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis

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The p53 control of apoptosis and proliferation: lessons from Drosophila

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Caught in the act – protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease

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A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer

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A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network

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p53’s Extended Reach: The Mutant p53 Secretome

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TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing

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Structural diversity of p63 and p73 isoforms

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p53, Aerobic Metabolism, and Cancer

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p53 activity is selectively licensed in the Drosophila stem cell compartment

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Regulation and function of p53: A perspective from Drosophila studies

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Transposons, p53 and Genome Security

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SOG 1‐dependent NAC 103 modulates the DNA damage response as a transcriptional regulator in Arabidopsis

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The p73 Tumor Suppressor Is Targeted by Pirh2 RING Finger E3 Ubiquitin Ligase for the Proteasome-dependent Degradation

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Proteasome Activation to Combat Proteotoxicity

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The Δ133p53 Isoforms, Tuners of the p53 Pathway

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Thymic and Postthymic Regulation of Naïve CD4+T-Cell Lineage Fates in Humans and Mice Models

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Metabolic regulation of oxygen and redox homeostasis by p53: Lessons from evolutionary biology?

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LZ-106, a novel analog of enoxacin, inducing apoptosis via activation of ROS-dependent DNA damage response in NSCLCs

Yang, L., Yuan, Y., Fu, C., Xu, X., Zhou, J., Wang, S., Kong, L., Li, Z., Guo, Q., & Wei, L. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.03.007 · Cited by 35 · see citing works

A p53 enhancer region regulates target genes through chromatin conformations in cis and in transPreprint

Link, N., Kurtz, P., O’Neal, M. A., Garcia-Hughes, G., & Abrams, J. (2013) · Genes & Development · doi:10.1101/gad.225565.113 · Cited by 36 · see citing works

p53

Wang, P., Zhuang, J., & Hwang, P. M. (2011) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32834de1d8 · Cited by 34 · see citing works

PACS-2 mediates the ATM and NF-κB-dependent induction of anti-apoptotic Bcl-xL in response to DNA damage

González, J. B., Auclair, S., Luan, S., Thomas, L., Atkins, K. M., Aslan, J. E., Thomas, L., Zhao, J., Zhao, Y., & Thomas, G. (2016) · Cell Death and Differentiation · doi:10.1038/cdd.2016.23 · Cited by 34 · see citing works

SMG7 is a critical regulator of p53 stability and function in DNA damage stress response

Luo, H., Cowen, L. E., Yu, G., Jiang, W. G., & Tang, Y. (2016) · Cell Discovery · doi:10.1038/celldisc.2015.42 · Cited by 33 · see citing works

The p53–Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humansPreprint

Coffill, C. R., Lee, A., Siau, J. W., Chee, S. M. Q., Joseph, T. L., Tan, Y. S., Madhumalar, A., Tay, B.-H., Brenner, S., Verma, C. S., et al. (2016) · Genes & Development · doi:10.1101/gad.274118.115 · Cited by 34 · see citing works

The Elephant Evolved p53 Isoforms that Escape MDM2-Mediated Repression and Cancer

Padariya, M., Jooste, M.-L., Hupp, T., Fåhraeus, R., Vojtesek, B., Vollrath, F., Kalathiya, U., & Karakostis, K. (2022) · Molecular Biology and Evolution · doi:10.1093/molbev/msac149 · Cited by 33 · see citing works

Evolution of the p53-MDM2 pathway

Åberg, E., Saccoccia, F., Grabherr, M. G., Ore, W. Y. J., Jemth, P., & Hultqvist, G. (2017) · BMC Evolutionary Biology · doi:10.1186/s12862-017-1023-y · Cited by 32 · see citing works

Characterization of p53 Family Homologs in Evolutionary Remote Branches of Holozoa

Bartas, M., Brázda, V., Červeň, J., & Pečínka, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010006 · Cited by 30 · see citing works

The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans

Mateo, A.-R. F., Kessler, Z., Jolliffe, A. K., McGovern, O. L., Yu, B., Nicolucci, A. C., Yanowitz, J. L., & Derry, W. B. (2016) · Current Biology · doi:10.1016/j.cub.2016.03.036 · Cited by 29 · see citing works

p53 in the game of transposons

Wylie, A., Jones, A. E., & Abrams, J. (2016) · BioEssays · doi:10.1002/bies.201600115 · Cited by 28 · see citing works

Repression of Puma by Scratch2 is required for neuronal survival during embryonic development

Rodríguez-Aznar, E., & Nieto, M. A. (2011) · Cell Death and Differentiation · doi:10.1038/cdd.2010.190 · Cited by 28 · see citing works

Dissecting protein architecture with communication blocks and communicating segment pairs

Karami, Y., Laine, É., & Carbone, A. (2016) · BMC Bioinformatics · doi:10.1186/s12859-015-0855-y · Cited by 28 · see citing works

The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review

Zhao, Q., Ma, Y., Li, Z., Zhang, K., Zheng, M., & Zhang, S. (2020) · Stem Cells International · doi:10.1155/2020/8835714 · Cited by 27 · see citing works

From tumor prevention to therapy: Empowering p53 to fight back

Frezza, C., & Martins, C. P. (2012) · Drug Resistance Updates · doi:10.1016/j.drup.2012.10.001 · Cited by 27 · see citing works

Characterization of cDNAs encoding p53 of Bombyx mori and Spodoptera frugiperda

Huang, N., Clem, R. J., & Rohrmann, G. F. (2011) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2011.03.014 · Cited by 26 · see citing works

Tumor-suppressive p53 Signaling Empowers Metastatic Inhibitor KLF17-dependent Transcription to Overcome Tumorigenesis in Non-small Cell Lung Cancer

Ali, A., Bhatti, M. Z., Shah, A. S., Duong, H., Alkreathy, H. M., Mohammad, S. F., Khan, R. A., & Ahmad, A. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.635730 · Cited by 26 · see citing works

Gene networks and toxicity/detoxification pathways in juvenile largemouth bass (Micropterus salmoides) liver induced by acute lead stress

Qian, B., Xue, L., Qi, X., Bai, Y., & Wu, Y. (2019) · Genomics · doi:10.1016/j.ygeno.2019.06.023 · Cited by 25 · see citing works

p53 and p63 Proteoforms Derived from Alternative Splicing Possess Differential Seroreactivity in Colorectal Cancer with Distinct Diagnostic Ability from the Canonical Proteins

Montero‐Calle, A., Garranzo‐Asensio, M., Torrente-Rodríguez, R. M., Montiel, V. R., Poves, C. F., Dziaková, J., Sanz, R., del Arco, C. D., Pingarrón, J. M., Fernández‐Aceñero, M. J., et al. (2023) · Cancers · doi:10.3390/cancers15072102 · Cited by 25 · see citing works

Variations in p53-like cDNA sequence are correlated with mussel haemic neoplasia: A potential molecular-level tool for biomonitoring

Vassilenko, E. I., Muttray, A. F., Schulte, P. M., & Baldwin, S. A. (2010) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2010.06.001 · Cited by 23 · see citing works

Structure and Stability Insights into Tumour Suppressor p53 Evolutionary Related Proteins

Pagano, B., Jama, A., Martinez, P., Akanho, E., Bui, T. T. T., Drake, A. F., Fraternali, F., & Nikolova, P. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076014 · Cited by 23 · see citing works

Drosophila p53 directs nonapoptotic programs in postmitotic tissue

Kurtz, P., Jones, A. E., Tiwari, B., Link, N., Wylie, A., Tracy, C., Krämer, H., & Abrams, J. (2019) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-12-0791 · Cited by 22 · see citing works

Functional relationship between p53 and RUNX proteins

Bae, S., Kolinjivadi, A. M., & Ito, Y. (2018) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjy076 · Cited by 22 · see citing works

Evolutionary history of the reprimo tumor suppressor gene family in vertebrates with a description of a new reprimo gene lineage

Wichmann, I. A., Zavala, K., Hoffmann, F. G., Vandewege, M. W., Corvalán, A. H., Amigo, J. D., Owen, G. I., & Opazo, J. C. (2016) · Gene · doi:10.1016/j.gene.2016.07.036 · Cited by 22 · see citing works

On the Origin of Biomolecular Networks

Janwa, H., Massey, S. E., Velev, J. P., & Mishra, B. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00240 · Cited by 21 · see citing works

Intrinsic apoptosis is evolutionarily divergent among metazoans

Krasovec, G., Horkan, H. R., Quéinnec, É., & Chambon, J. (2023) · Evolution Letters · doi:10.1093/evlett/qrad057 · Cited by 21 · see citing works

P53 at the start of the 21st century: lessons from elephants

Haupt, S., & Haupt, Y. (2017) · F1000Research · doi:10.12688/f1000research.12682.1 · Cited by 20 · see citing works

Loss of function tp53 mutations do not accelerate the onset of myc‐induced T‐cell acute lymphoblastic leukaemia in the zebrafish

Gutiérrez, A., Feng, H., Stevenson, K. E., Neuberg, D. S., Calzada, O., Zhou, Y., Langenau, D. M., & Look, A. T. (2014) · British Journal of Haematology · doi:10.1111/bjh.12851 · Cited by 18 · see citing works

Evolution of oncogenic signatures of mutation hotspots in tyrosine kinases supports the atavistic hypothesis of cancer

Chen, W., Li, Y., & Wang, Z. (2018) · Scientific Reports · doi:10.1038/s41598-018-26653-5 · Cited by 18 · see citing works

The specific seroreactivity to ∆Np73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein

Garranzo‐Asensio, M., Guzmán‐Aránguez, A., Poves, C. F., Fernández‐Aceñero, M. J., Montero‐Calle, A., Cerón, M. Á., Fernández-Díez, S., Rodríguez, N., de Cedrón, M. G., de Molina, A. R., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-49960-x · Cited by 17 · see citing works

Mollusca: Disseminated Neoplasia in Bivalves and the p53 Protein Family

Muttray, A. F., & Vassilenko, K. (2018) · Springer eBooks · doi:10.1007/978-3-319-76768-0_28 · Cited by 15 · see citing works

Tumor malignancy is engaged to prokaryotic homolog toolbox

Fernandes, J., Guedes, P. G., Lage, C. L. S., Rodrigues, J. C. F., & Lage, C. A. S. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2011.12.014 · Cited by 15 · see citing works

Myelodysplastic Syndromes with Isolated del(5q): Value of Molecular Alterations for Diagnostic and Prognostic Assessment

Acha, P., Mallo, M., & Solé, F. G. (2022) · Cancers · doi:10.3390/cancers14225531 · Cited by 14 · see citing works

The TP53 fertility network

Paskulin, D. D., Paixão‐Côrtes, V. R., Hainaut, P. L., Bortolini, M. C., & Ashton‐Prolla, P. (2012) · Genetics and Molecular Biology · doi:10.1590/s1415-47572012000600008 · Cited by 15 · see citing works

Tumor Immunology Viewed from Alternative Animal Models—the Xenopus Story

Banach, M., & Robert, J. (2017) · Current Pathobiology Reports · doi:10.1007/s40139-017-0125-y · Cited by 15 · see citing works

Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells

Liu, Z., Zhang, C., Skamagki, M., Khodadadi‐Jamayran, A., Zhang, W., Kong, D., Chang, C.-W., Feng, J., Han, X., Townes, T. M., et al. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.10.006 · Cited by 15 · see citing works

Evolutionary Adaptations to Risk of Cancer

Greaves, M. F., & Ermini, L. (2015) · JAMA · doi:10.1001/jama.2015.13153 · Cited by 14 · see citing works

The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R

Panni, S., Salvioli, S., Santonico, E., Langone, F., Storino, F., Altilia, S., Franceschi, C., Cesareni, G., & Castagnoli, L. (2014) · The Journal of Biochemistry · doi:10.1093/jb/mvu059 · Cited by 14 · see citing works

Evolution of p53 Transactivation Specificity through the Lens of a Yeast-Based Functional Assay

Lion, M., Raimondi, I., Donati, S., Jousson, O., Ciribilli, Y., & Inga, A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116177 · Cited by 13 · see citing works

Evolutionary determinants of curability in cancer

Mansur, M. B., deSouza, N. M., Natrajan, R., Abegglen, L. M., Schiffman, J. D., & Greaves, M. F. (2023) · Nature Ecology & Evolution · doi:10.1038/s41559-023-02159-w · Cited by 13 · see citing works

G1 phase cell cycle arrest in NSCLC in response to LZ-106, an analog of enoxacin, is orchestrated through ROS overproduction in a P53-dependent manner

Yang, L., Zhou, J., Meng, F., Fu, C., Zou, X., Liu, J., Zhang, C., Tan, R. X., Li, Z., Guo, Q., et al. (2018) · Carcinogenesis · doi:10.1093/carcin/bgy124 · Cited by 13 · see citing works

Molecular evolutionary patterns of NAD+/Sirtuin aging signaling pathway across taxa

Gaur, U., Tu, J., Li, D., Gao, Y., Lian, T., Sun, B., Yang, D., Fan, X., & Yang, M. (2017) · PLoS ONE · doi:10.1371/journal.pone.0182306 · Cited by 12 · see citing works

Convergent TP53 loss and evolvability in cancer

Mansur, M. B., & Greaves, M. F. (2023) · BMC Ecology and Evolution · doi:10.1186/s12862-023-02146-6 · Cited by 12 · see citing works

Neuronal IL-17 controls Caenorhabditis elegans developmental diapause through CEP-1/p53

Godthi, A., Min, S., Das, S., Cruz-Corchado, J., Deonarine, A., Misel‐Wuchter, K., Issuree, P. D. A., & Prahlad, V. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2315248121 · Cited by 11 · see citing works

Dipeptide analysis of p53 mutations and evolution of p53 family proteins

Huang, Q., Yu, L., Levine, A. J., Nussinov, R., & Ma, B. (2013) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2013.04.002 · Cited by 12 · see citing works

TP53 germline pathogenic variants in modern humans were likely originated during recent human history

Kou, S. H., Li, J., Tam, B., Lei, H., Zhao, B., Xiao, F., & Wang, S. M. (2023) · NAR Cancer · doi:10.1093/narcan/zcad025 · Cited by 11 · see citing works

A platform for interrogating cancer-associated p53 alleles

D’Brot, A., Kurtz, P., Regan, E. A., Jakubowski, B., & Abrams, J. (2016) · Oncogene · doi:10.1038/onc.2016.48 · Cited by 10 · see citing works

The Genome of the Softshell Clam Mya arenaria and the Evolution of Apoptosis

Plachetzki, D. C., Pankey, M. S., MacManes, M. D., Lesser, M. P., & Walker, C. W. (2020) · Genome Biology and Evolution · doi:10.1093/gbe/evaa143 · Cited by 8 · see citing works

Unpicking the Roles of DNA Damage Protein Kinases in Trypanosomatids

Silva, G. L. A., Tosi, L. R. O., McCulloch, R., & Black, J. A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.636615 · Cited by 6 · see citing works

Distinct dosage compensations of ploidy-sensitive and -insensitive X chromosome genes during development and in diseases

Guo, M., Fang, Z., Chen, B., Songyang, Z., & Xiong, Y. (2023) · iScience · doi:10.1016/j.isci.2023.105997 · Cited by 4 · see citing works

Pathobiology of Acute Lymphoblastic Leukemia

Burns, M., Armstrong, S. A., & Gutiérrez, A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35762-3.00064-0 · Cited by 4 · see citing works

Starvation resistance in planarians: multiple strategies to get a thrifty phenotype

Gambino, G., Iacopetti, P., Ippolito, C., Salvetti, A., & Rossi, L. (2023) · FEBS Journal · doi:10.1111/febs.17020 · Cited by 4 · see citing works

Comparative Study of Cellular Tumor Antigen p53 Protein of Fishes and Analysis of its Protein Interaction Network using Computational Approach

Kumari, S., Rasal, K. D., Sundaray, J. K., Nandi, S., & Jayasankar, P. (2015) · Computational Molecular Biology · doi:10.5376/cmb.2015.05.0003 · Cited by 3 · see citing works

Towards reconstructing the dipteran demise of an ancient essential gene: E3 ubiquitin ligase Murine double minute

Jasti, N., Sebagh, D., Riaz, M., Wang, X., Koripella, B., Palanisamy, V., Mohammad, N., Chen, Q., & Friedrich, M. (2020) · Development Genes and Evolution · doi:10.1007/s00427-020-00663-8 · Cited by 3 · see citing works

Discovery of novel 1H-benzo[d]imidazole-4,7-dione based transglutaminase 2 inhibitors as p53 stabilizing anticancer agents in renal cell carcinoma

Kim, G., Kang, J. H., Kim, H. J., Im, E., Bae, J., Kwon, W. S., Rha, S. Y., Chung, H. C., Cho, E. Y., Kim, S.-Y., et al. (2023) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2023.107061 · Cited by 2 · see citing works

The development of p53 tumor diagnosis and drug design strategy in its disordered region

Zhang, Y. (2019) · E3S Web of Conferences · doi:10.1051/e3sconf/20197801001 · Cited by 2 · see citing works

Co nás učí nádory. Paralely v chování buněk a lidí

Šmardová, J. (2021) · Masarykova univerzita eBooks · doi:10.5817/cz.muni.m210-9700-2021 · Cited by 1 · see citing works

p53

Botcheva, K., & Anderson, C. W. (2012) · Springer eBooks · doi:10.1007/978-1-4419-0461-4_57 · Cited by 1 · see citing works

Molecular evolution of the p53 network in reptiles

Parsai, S. (2013) · Iowa State University Digital Repository (Iowa State University)

Identification and Characterization of the Drosophila Inverted Repeat Binding Complex

Francis, M. J. (2011) · eScholarship (California Digital Library)

Análise de polimorfismos da família p53 e sua via regulatória como fatores de risco para aneuploidia

Boquett, J. A. (2013) · Americanae (AECID Library)

Characterization of p53 in rainbow trout cell lines

Liu, M. (2010) · UWSpace (University of Waterloo)

p53 Research: The Past Thirty Years and the Next Thirty YearsPreprint

Lane, D. P., & Levine, A. J. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000893 · Cited by 450 · see citing works

The role of p53 in reproduction, an unexpected function for a tumor suppressor

Hu, W., & Feng, Z. (2019) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjz072 · Cited by 9 · see citing works

The Evolution of Tumor Suppressing Genes in Multicellular Organisms: Nature’s Prevention of Oncogenesis

Perez, M. (2024) · FIU Undergraduate Research Journal · doi:10.25148/urj.020118

Reassessing the role of p53 in cancer and ageing from an evolutionary perspective

Aranda-Anzaldo, A., & Dent, M. A. R. (2007) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2007.01.001 · Cited by 36 · see citing works

p53 — a Jack of all trades but master of none

Junttila, M. R., & Evan, G. I. (2009) · Nature reviews. Cancer · doi:10.1038/nrc2728 · Cited by 344 · see citing works