MYC: connecting selective transcriptional control to global RNA production

Kress, Theresia R., Sabò, Arianna, Amati, Bruno·2015·Nature reviews. Cancer

DOI 10.1038/nrc3984

Cited by (519)

Items 101–200 of 519

Recent advances in searching c-Myc transcriptional cofactors during tumorigenesis
Matteo Caforio, Cristina Sorino, Stefano Iacovelli, Maurizio Fanciulli, Franco Locatelli, Valentina Folgiero · 2018 · Journal of Experimental & Clinical Cancer Research
Targeting MYC Proteins for Tumor Therapy
Elmar Wolf, Martin Eilers · 2019 · Annual Review of Cancer Biology
MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
Dimitrios Papadopoulos, Daniel Solvie, Apoorva Baluapuri, Theresa Endres, Stefanie Anh Ha, Steffi Herold, Jacqueline Kalb, Celeste Giansanti, Christina Schülein‐Völk, Carsten Patrick Ade et al. · 2021 · Molecular Cell
The crosstalk between metabolism and translation
Stefano Biffo, Davide Ruggero, Massimo Mattia Santoro · 2024 · Cell Metabolism
RNA Therapeutics in Oncology: Advances, Challenges, and Future Directions
A. Robert MacLeod, Stanley T. Crooke · 2017 · The Journal of Clinical Pharmacology
MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
Dharmendra D Dingar, William B. Tu, Diana Resetca, Corey Lourenco, Aaliya Tamachi, Jason De Melo, Kathleen E. Houlahan, Manpreet Kalkat, Pak-Kei Chan, Paul Christopher Boutros et al. · 2018 · Nature Communications
Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
Theresia R. Kress, Paola Pellanda, Luca Pellegrinet, Valerio Bianchi, Paola Nicoli, Mirko Doni, Camilla Recordati, Salvatore Bianchi, Luca Rotta, Thelma Capra et al. · 2016 · Cancer Research
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression
Austin G. Holmes, J. Brandon Parker, Vinay Sagar, Mihai Ioan Truica, Pritin N. Soni, Huiying Han, Gary E. Schiltz, Sarki Abba Abdulkadir, Debabrata Chakravarti · 2022 · Science Advances
Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription
Giacomo Cossa, Isabelle Röschert, Florian Prinz, Apoorva Baluapuri, Raphael Silveira Vidal, Christina Schülein‐Völk, Yun-Chien Chang, Carsten Patrick Ade, Guido Mastrobuoni, Cyrille Girard et al. · 2020 · Molecular Cell
Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm
Sho Kubota, K. Tokunaga, Tomohiro Umezu, Takako Yokomizo-Nakano, Yuqi Sun, M. Oshima, K. Tan, Henry Yang, A. Kanai, Eisaku Iwanaga et al. · 2019 · Nature Communications
In vivo Reprogramming of Cancer Metabolism by MYC
Roman Camarda, Jeremy R. Williams, Andrei Goga · 2017 · Frontiers in Cell and Developmental Biology
A nuclear lncRNA Linc00839 as a Myc target to promote breast cancer chemoresistance via PI3K/AKT signaling pathway
Qi Chen, Huiling Shen, Xiaolan Zhu, Yueqin Liu, Hui Yang, Hui Chen, Shangwan Xiong, Huamao Chi, Wenlin Xu · 2020 · Cancer Science
Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs
Allevato, Michael, Bolotin, Eugene, Grossman, Mark, Mane-Padros, Daniel, Sladek, Frances M., Martinez, Ernest · 2017 · PLOS ONE
UHRF1-KAT7-mediated regulation of TUSC3 expression via histone methylation/acetylation is critical for the proliferation of colon cancer cells
Kenzui Taniue, Tomoatsu Hayashi, Yuki Kamoshida, Akiko Kurimoto, Yasuko Takeda, Lumi Negishi, Kei Iwasaki, Yoshifumi Kawamura, Naoki Goshima, Tetsu Akiyama · 2019 · Oncogene
OLR1 Promotes Pancreatic Cancer Metastasis via Increased c-Myc Expression and Transcription of HMGA2
Gang Yang, Guangbing Xiong, Mengyu Feng, Fangyu Zhao, Jiangdong Qiu, Yueze Liu, Zhe Cao, Huanyu Wang, Jinshou Yang, Lei You et al. · 2020 · Molecular Cancer Research
Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation
Stefano de Pretis, Theresia R. Kress, Marco J. Morelli, Arianna Sabò, C.V. Locarno, Alessandro Verrecchia, Mirko Doni, Stefano Campaner, Bruno B. Amati, Mattia Pelizzola · 2017 · Genome Research
Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton et al. · 2020 · Nature Communications
MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors
Laura M. Urbanski, Mattia Brugiolo, SungHee Park, Brittany Lynn Angarola, Nathan K. Leclair, Marina Yurieva, Phil Palmer, Sangram Keshari Sahu, Olga Anczuków · 2022 · Cell Reports
Neuroblastoma: A Tough Nut to Crack
Frank Speleman, Julie R. Park, Tara Olive Henderson · 2016 · American Society of Clinical Oncology Educational Book
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
Marta Palomo-Irigoyen, Encarnación Pérez-Andrés, Marta Iruarrizaga‐Lejarreta, Adrián Barreira-Manrique, Miguel Tamayo-Caro, Laura Vila-Vecilla, Leire Moreno‐Cugnon, Nagore Beitia, Daniela Medrano, David Fernández‐Ramos et al. · 2020 · Journal of Clinical Investigation
Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters
Theresa Endres, Daniel Solvie, Jan B. Heidelberger, Valentina Andrioletti, Apoorva Baluapuri, Carsten Patrick Ade, Matthias Muhar, Ursula Eilers, Seychelle M. Vos, Patrick Cramer et al. · 2021 · Molecular Cell
Low-intensity pulsed ultrasound (LIPUS) enhances the anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles
Xueke Li, Yi Zhong, Wuqi Zhou, Yishu Song, Wenqu Li, Qiaofeng Jin, Tang Gao, Li Zhang, Mingxing Xie · 2023 · Cellular & Molecular Biology Letters
Regulation of gene expression in human cancers by TRIM24
Srikanth Appikonda, Kaushik N. Thakkar, Michelle Craig Barton · 2016 · Drug Discovery Today Technologies
MYC inhibition increases PD-L1 expression induced by IFN-γ in hepatocellular carcinoma cells
Zou, Jiahuan, Zhuang, Mengwei, Yu, Xiaopeng, Li, Na, Mao, Rudi, Wang, Zhida, Wang, Jianing, Wang, Xiaoyan, Zhou, Huaiyu, Zhang, Lining et al. · 2018 · Molecular Immunology
MYC in Germinal Center‐derived lymphomas: Mechanisms and therapeutic opportunities
Andrea Bisso, Arianna Sabò, Bruno B. Amati · 2019 · Immunological Reviews
Demystifying the Druggability of the MYC Family of Oncogenes
Nishant M. Karadkhelkar, Mingliang Lin, Lisa M. Eubanks, Kim D. Janda · 2023 · Journal of the American Chemical Society
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer
Houliang Deng, Xiaowen Guan, Longcai Gong, Jianming Zeng, Hongjie Zhang, Mike Y. Chen, Gang Li · 2019 · Scientific Reports
Targeting the MYC Ubiquitination-Proteasome Degradation Pathway for Cancer Therapy
Xiao‐Xin Sun, Yanping Li, Rosalie C. Sears, Mu‐Shui Dai · 2021 · Frontiers in Oncology
Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors
Elisa Donato, Ottavio Croci, Arianna Sabò, Heiko Müller, Marco J. Morelli, Mattia Pelizzola, Stefano Campaner · 2016 · Leukemia
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
Axel Hyrenius-Wittsten, Mattias Pilheden, Helena Sturesson, Jenny Hansson, Michael Walsh, G. Song, J. Kazi, Jian Liu, R. Ramakrishan, C. García-Ruiz et al. · 2018 · Nature Communications
RBP EIF2S2 Promotes Tumorigenesis and Progression by Regulating MYC-Mediated Inhibition via FHIT-Related Enhancers
Jiwei Zhang, Shengli Li, Ling Zhang, Juan Xu, Mingxu Song, Tingting Shao, Zhaohui Huang, Yongsheng Li · 2020 · Molecular Therapy
MYCN and Metabolic Reprogramming in Neuroblastoma
Mohit Bansal, Anamika Gupta, Han‐Fei Ding · 2022 · Cancers
Therapeutic Targeting of MYC in Head and Neck Squamous Cell Carcinoma
Shuo Liu, Zhen Qin, Yaqing Mao, Wenbo Zhang, Yujia Wang, Lingfei Jia, Xin Peng · 2022 · OncoImmunology
Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells
Luca Fagnocchi, Alessio Zippo · 2017 · Frontiers in Cell and Developmental Biology
CRISPR/Cas9/AAV9-mediated in vivo editing identifies MYC regulation of 3D genome in skeletal muscle stem cell
Liangqiang He, Yingzhe Ding, Yu Fen Zhao, Karl Kam Hei So, Xianlu L. Peng, Yuying Li, Jie Yuan, Zhiming He, Xiaona Chen, Hao Sun et al. · 2021 · Stem Cell Reports
CircCDYL inhibits the expression of C-MYC to suppress cell growth and migration in bladder cancer
Jiayin Sun, Hui Zhang, Dan Tao, Fei Xie, Feng Liu, Chaohui Gu, Miao Wang, Liang Wang, Guosong Jiang, Zhendi Wang et al. · 2019 · Artificial Cells Nanomedicine and Biotechnology
Integrated requirement of non‐specific and sequence‐specific DNA binding in Myc‐driven transcription
Paola Pellanda, Mattia Dalsass, M. Filipuzzi, Alessia Loffreda, Alessandro Verrecchia, Virginia Castillo Cano, Hugo Thabussot, Mirko Doni, Marco J. Morelli, Laura Soucek et al. · 2021 · The EMBO Journal
Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content
Carmen Morcelle, Sandra Menoyo, Francisco D. Morón-Duran, Albert Tauler, Sara C. Kozma, George Thomas, Antonio Gentilella · 2019 · Cancer Research
Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
Bethany L. Veo, Etienne P. Danis, Angela M. Pierce, Dong Wang, Susan P. Fosmire, Kelly D. Sullivan, Molishree Joshi, Santosh Khanal, Nathan A. Dahl, Sana D. Karam et al. · 2021 · Cell Reports
Pin1 is required for sustained B cell proliferation upon oncogenic activation of Myc
Luana D’Artista, Andrea Bisso, Andrea Piontini, Mirko Doni, Alessandro Verrecchia, Theresia R. Kress, Marco J. Morelli, Giannino Del Sal, Bruno B. Amati, Stefano Campaner · 2016 · Oncotarget
Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancer
Zhenhua Yang, Kushani K. Shah, Theodore Busby, Keith Giles, Alireza Khodadadi‐Jamayran, Wei Li, Hao Jiang · 2018 · Journal of Clinical Investigation
Targeting MYCN in Molecularly Defined Malignant Brain Tumors
Anna Borgenvik, Matko Čančer, Sonja Hutter, Fredrik J. Swartling · 2021 · Frontiers in Oncology
MYC-Induced Replicative Stress: A Double-Edged Sword for Cancer Development and Treatment
Laura Curti, Stefano Campaner · 2021 · International Journal of Molecular Sciences
Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor–positive Breast Cancer
Cristina Guarducci, Agostina Nardone, Douglas Russo, Zsuzsanna Nagy, Capucine Héraud, Albert Grinshpun, Qi Zhang, Allegra Freelander, Matthew Joseph Leventhal, Avery S. Feit et al. · 2024 · Clinical Cancer Research
c-MYC regulates mRNA translation efficiency and start-site selection in lymphoma
Kamini Singh, Jianan Lin, Yi Zhong, Antonija Burčul, Prathibha Mohan, Man Jiang, Liping Laura Sun, Vladimir Yong‐Gonzalez, Agnes J. Viale, Justin R. Cross et al. · 2019 · The Journal of Experimental Medicine
The role of MYC in the transformation and aggressiveness of ‘indolent’ B-cell malignancies
Daniel Filip, Marek Mráz · 2019 · Leukemia & lymphoma/Leukemia and lymphoma
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells
Ting La, Song Chen, Tao Guo, Xiao Hong Zhao, Teng Liu, Dandan Li, Michael J. Carnell, Yuan Yuan Zhang, Yuchen Feng, Nicole Cole et al. · 2021 · Theranostics
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma
Xijuan Chen, Qin Liu, Yingyao Chen, Lixuan Wang, Rongchun Yang, Weilin Zhang, Xue Pan, Siyuan Zhang, Chuwen Chen, Tong Wu et al. · 2022 · Molecular Metabolism
Targeting protein disorder: the next hurdle in drug discovery
Tamás Lázár, Acadia Connor, Charles F. DeLisle, Virginia Burger, Péter Tompa · 2025 · Nature Reviews Drug Discovery
Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control
Shuju Luo, Jinmin Zhao, Mitra Fowdur, Kun Wang, Tenglong Jiang, Maolin He · 2016 · Scientific Reports
Is Myc an Important Biomarker? Myc Expression in Immune Disorders and Cancer
Shivtia Trop-Steinberg, Yehudit Azar · 2017 · The American Journal of the Medical Sciences
AMPK promotes survival of c‐Myc‐positive melanoma cells by suppressing oxidative stress
Alain Kfoury, Marzia Armaro, Caterina Collodet, Jessica Sordet‐Dessimoz, Maria Pilar Giner, Stefan Christen, Sofia Moco, Marion Leleu, Laurence de Leval, Ute Koch et al. · 2018 · The EMBO Journal
MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition
Rand, Tim A., Sutou, Kenta, Tanabe, Koji, Jeong, Daeun, Nomura, Masaki, Kitaoka, Fumiyo, Tomoda, Emi, Narita, Megumi, Nakamura, Michiko, Nakamura, Masahiro et al. · 2018 · Cell Reports
Developmental vascular regression is regulated by a Wnt/β-catenin, MYC, P21 (CDKN1A) pathway that controls cell proliferation and cell death
Gowri Nayak, Yoshinobu Odaka, Vikram Prasad, Alyssa F. Solano, Eun-Jin Yeo, Shruti Vemaraju, Jeffery D. Molkentin, Andreas Trumpp, Bart O. Williams, Sujata Rao et al. · 2018 · Development
Estrogen-independent Myc overexpression confers endocrine therapy resistance on breast cancer cells expressing ERαY537S and ERαD538G mutations
Liqun Yu, Lawrence Wang, Chengjian Mao, Darjan Duraki, Ji Eun Kim, Rui Huang, William G. Helferich, Erik Russell Nelson, Ben Ho Park, David J. Shapiro · 2018 · Cancer Letters
c-Myc transactivates GP73 and promotes metastasis of hepatocellular carcinoma cells through GP73-mediated MMP-7 trafficking in a mildly hypoxic microenvironment
Yiming Liu, Sining Zhou, Jieyao Shi, Xiaodi Zhang, Linhui Shentu, Zhi Chen, Linfu Zhou · 2019 · Oncogenesis
RETRACTED: How microRNAs affect the PD-L1 and its synthetic pathway in cancer
Gholamreza Rezaei Danbaran, Saeed Aslani, Nadia Sharafkandi, Maryam Hemmatzadeh, Ramin Hosseinzadeh, Gholamreza Azizi, Farhad Jadidi‐Niaragh, Farhad Babaie, Hamed Mohammadi · 2020 · International Immunopharmacology · Retracted
MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR
Sanjib Chaudhary, Appadurai Muthamil Iniyan, Shailendra Kumar Maurya, Palanisamy Nallasamy, Saravanakumar Marimuthu, Ashu Shah, Pranita Atri, Chirravuri Venkata Ramakanth, Subodh M. Lele, Parthasarathy Seshacharyulu et al. · 2023 · Breast Cancer Research
Comprehensive network of miRNA-induced intergenic interactions and a biological role of its core in cancer
Vladimir Galatenko, A. V. Galatenko, Timur R. Samatov, Andrey A. Turchinovich, M. Yu. Shkurnikov, Julia Alekseevna Makarova, Alexander Tonevitsky · 2018 · Scientific Reports
BRD4 and MYC—clarifying regulatory specificity
Arianna Sabò, Bruno B. Amati · 2018 · Science
The Role of MYC and PP2A in the Initiation and Progression of Myeloid Leukemias
Raffaella Pippa, Maria Dolores Odero · 2020 · Cells
LncRNA KCNQ1OT1 activated by c-Myc promotes cell proliferation via interacting with FUS to stabilize MAP3K1 in acute promyelocytic leukemia
Doudou Tang, Yujiao Luo, Yafeng Jiang, Piao Hu, Hongling Peng, Shangjie Wu, Guangsen Zhang, Yewei Wang · 2021 · Cell Death and Disease
RvD1 inhibits TNFα-induced c-Myc expression in normal intestinal epithelial cells and destabilizes hyper-expressed c-Myc in colon cancer cells
Xiancai Zhong, Hana Lee, Young‐Joon Surh · 2018 · Biochemical and Biophysical Research Communications
BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141
Yukun Liu, Ran Zhao, Yanmei Wei, Mengna Li, Heran Wang, Weihong Niu, Yao Zhou, Yuanzheng Qiu, Songqing Fan, Yihao Zhan et al. · 2018 · Journal of Experimental & Clinical Cancer Research
Super-enhancers: A new frontier for glioma treatment
Meng Cheng, Zheng Wei Zhang, Xing Ji, Yadi Xu, Erbao Bian, Bing Zhao · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
N-myc regulates growth and fiber cell differentiation in lens development
Gabriel R. Cavalheiro, Gabriel E. Matos-Rodrigues, Yilin Zhao, Anielle L. Gomes, Deepti Anand, Danilo Predes, Silmara de Lima, José G. Abreu, Deyou Zheng, Salil A. Lachke et al. · 2017 · Developmental Biology
Primary transcripts: From the discovery of RNA processing to current concepts of gene expression ‐ Review
Klaus Scherrer · 2018 · Experimental Cell Research
MYC Induces a Hybrid Energetics Program Early in Cell Reprogramming
Javier Prieto, Arnold Young Seo, Marian León, Fulvio Santacatterina, Laura Torresano, Martina Palomino‐Schätzlein, Karen Giménez-Orenga, Azahara Vallet-Sánchez, Xavier Ponsoda, Antonio Pineda‐Lucena et al. · 2018 · Stem Cell Reports
Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells
Clément Bonamy, Emmanuel Séchet, Aurélien Amiot, Antoine Alam, Michaël Mourez, Laurent Fraisse, Philippe Jean Sansonetti, Brice Sperandio · 2018 · Scientific Reports
Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer
Cheng S. Jin, Feng‐Lai Yuan, Yuanlong Gu, Xia Li, Minfeng Liu, Xiaomin Shen, Bo Liu, Maoqun Zhu · 2016 · Oncotarget
Retracted: Long non‐coding RNA ARAP1‐AS1 promotes tumorigenesis and metastasis through facilitating proto‐oncogene c‐Myc translation via dissociating PSF/PTB dimer in cervical cancer
Yao Zhang, Dan Wu, Dian Wang · 2020 · Cancer Medicine · Retracted
Role of tumor microenvironment in the regulation of PD‐L1: A novel role in resistance to cancer immunotherapy
Nirvana Kalantari Khandani, Atefeh Ghahremanloo, Seyed Isaac Hashemy · 2020 · Journal of Cellular Physiology
Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage
Joffrey Pelletier, Ferran Riaño‐Canalias, Eugènia Almacellas, Caroline Mauvezin, Sara Samino, Sònia Feu, Sandra Menoyo, Ana Domostegui, Marta Garcia‐Cajide, Ramón Salazar et al. · 2020 · The EMBO Journal
Beyond gene expression: how MYC relieves transcription stress
Dimitrios Papadopoulos, Leonie Uhl, Stefanie Anh Ha, Martin Eilers · 2023 · Trends in cancer
m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
Évelyne Collignon, Brandon Cho, Giacomo Furlan, Julie Fothergill-Robinson, Sylvia-Bryn Martin, Sarah A. McClymont, Robert L. Ross, Patrick A. Limbach, Miguel Ramalho‐Santos · 2023 · Nature Cell Biology
Differentially Expressed Genes and Signature Pathways of Human Prostate Cancer
Jennifer S. Myers, Ariana K. von Lersner, Charles T. Robbins, Qing‐Xiang Amy Sang · 2015 · PLoS ONE
Molecular Regulation of Paused Pluripotency in Early Mammalian Embryos and Stem Cells
Vera Anna van der Weijden, Aydan Bulut-Karslıoğlu · 2021 · Frontiers in Cell and Developmental Biology
FGFR1 fusion kinase regulation of MYC expression drives development of stem cell leukemia/lymphoma syndrome
Tianxiang Hu, Qing Wu, Yating Chong, Haiyan Qin, Candace J. Poole, Jan van Riggelen, Mingqiang Ren, John Kenneth Cowell · 2018 · Leukemia
Divergent lncRNA MYMLR regulates MYC by eliciting DNA looping and promoter‐enhancer interaction
Taisuke Kajino, Teppei Shimamura, Shuyi Gong, Kiyoshi Yanagisawa, Lisa Ida, Masahiro Nakatochi, Sebastian Griesing, Yukako Shimada, Keiko Kano, Motoshi Suzuki et al. · 2019 · The EMBO Journal
Gene Transactivation and Transrepression in MYC-Driven Cancers
Marika Scafuro, Lucia Capasso, Vincenzo Carafa, Lucia Altucci, Angela Nebbioso · 2021 · International Journal of Molecular Sciences
Polyploidy and Myc Proto-Oncogenes Promote Stress Adaptation via Epigenetic Plasticity and Gene Regulatory Network Rewiring
O. V. Anatskaya, A. Vinogradov · 2022 · International Journal of Molecular Sciences
MiR‐376a suppresses the proliferation and invasion of non‐small‐cell lung cancer by targeting c‐Myc
Youyu Wang, Wei Cong, Gang Wu, Xueming Ju, Zhixi Li, Xin Duan, Xueli Wang, Hong Gao · 2017 · Cell Biology International
The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer
Sarah McCuaig, David Barras, Elizabeth H. Mann, Matthias Friedrich, Samuel J. Bullers, Alina Janney, Lucy C. Garner, Enric Domingo, Viktor Hendrik Koelzer, Mauro Delorenzi et al. · 2020 · Clinical Cancer Research
CDK12 controls transcription at damaged genes and prevents MYC-induced transcription-replication conflicts
Laura Curti, Sara Rohban, Nicola Bianchi, Ottavio Croci, Adrian Andronache, Sara Barozzi, Michela Mattioli, Fernanda Ricci, Elena Pastori, Silvia Sberna et al. · 2024 · Nature Communications
Methylarginine targeting chimeras for lysosomal degradation of intracellular proteins
Laurence J. Seabrook, Carolina N. Franco, Cody A. Loy, Jaida M. Osman, Callie Fredlender, Jan Zimak, Melissa Campos, Steven T. Nguyen, Richard L. Watson, Samantha R. Levine et al. · 2024 · Nature Chemical Biology
MNT and Emerging Concepts of MNT‐MYC Antagonism
Guang Yang, Peter J. Hurlin · 2017 · Genes
c-MYC amplification and c-myc protein expression in pancreatic acinar cell carcinomas. New insights into the molecular signature of these rare cancers
Stefano La Rosa, Barbara Bernasconi, Alessandro Vanoli, Amedeo Sciarra, Kenji Notohara, Luca Albarello, Selenia Casnedi, Paola Rita Billo, Lizhi Zhang, Maria Grazia Tibiletti et al. · 2018 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
Targeting liquid-liquid phase separation in pancreatic cancer
Yue Ming, Xia Chen, Yuanpei Xu, Yuanyuan Wu, Chenlu Wang, Tingting Zhang, Renfang Mao, Yihui Fan · 2019 · Translational Cancer Research
Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability
Zhiqiang Ma, Yingtong Feng, Kai Xia Guo, Dong Liu, Changjian Shao, Minghong Pan, Yimeng Zhang, Yuxi Zhang, Di Lu, Di Huang et al. · 2022 · Military Medical Research
Sox2‐dependent inhibition of p21 is associated with poor prognosis of endometrial cancer
Kaoru Yamawaki, Tatsuya Ishiguro, Yutaro Mori, Kosuke Yoshihara, Kazuaki Suda, Ryo Tamura, Masayuki Yamaguchi, Masayuki Sekine, Katsunori Kashima, Masaya Higuchi et al. · 2017 · Cancer Science
MACC1 mediates chemotherapy sensitivity of 5-FU and cisplatin via regulating MCT1 expression in gastric cancer
Chunlin Wang, Zhaowei Wen, Jianming Xie, Yang Zhao, Liang Zhao, Shuyi Zhang, Yajing Liu, Yan Xue, Min Shi · 2017 · Biochemical and Biophysical Research Communications
m1A inhibition fuels oncolytic virus-elicited antitumor immunity via downregulating MYC/PD-L1 signaling
Shu‐Jin Li, Feng Tian, Yuan‐Tong Liu, Qi‐Chao Yang, An Song, Shuo Wang, Jun Xie, Junjie Zhang, Bi‐Feng Yuan, Zhi‐Jun Sun · 2024 · International Journal of Oral Science
Che‐1 is targeted by c‐Myc to sustain proliferation in pre‐B‐cell acute lymphoblastic leukemia
Valentina Folgiero, Cristina Sorino, Matteo Pallocca, Francesca De Nicola, Frauke Goeman, Valentina Bertaina, Luisa Strocchio, Paolo Romania, Angela Pitisci, Simona Iezzi et al. · 2018 · EMBO Reports
Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death
Ana Domostegui, Suresh Peddigari, Carol A. Mercer, Flavia Iannizzotto, Marta Leonor Rodríguez, Marta Garcia‐Cajide, Virginia Amador, Sarah T. Diepstraten, Gemma L. Kelly, Ramón Salazar et al. · 2021 · Blood
Construction and validation of a novel gene signature for predicting the prognosis of osteosarcoma
Jinpo Yang, Anran Zhang, Huan Luo, Chao Ma · 2022 · Scientific Reports
A moving target: structure and disorder in pursuit of Myc inhibitors
Richard W. Bayliss, Selena G. Burgess, Eoin N. Leen, Mark W. Richards · 2017 · Biochemical Society Transactions
MYC-Targeting Inhibitors Generated from a Stereodiversified Bicyclic Peptide Library
Z. Li, Yi Huang, Ta I Hung, Jianan Sun, Desiree Aispuro, Boxi Chen, Nathan Guevara, Fei Ji, Cong Xu, Lingchao Zhu et al. · 2024 · Journal of the American Chemical Society
Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1
Shengqing Stan Gu, Wayne W. Chan, Golam Mohi, Joel Rosenbaum, Azin Sayad, Zhibin Lu, Carl Virtanen, Shaoguang Li, Benjamin G. Neel, Richard A. Van Etten · 2016 · Blood
C-Myc Signaling Pathway in Treatment and Prevention of Brain Tumors
Milad Ashrafizadeh, Ali Zarabi, Kiavash Hushmandi, Ebrahim Rahmani Moghadam, Farid Hashemi, Salman Daneshi, Fardin Hashemi, Shima Tavakol, Reza Mohammadinejad, Masoud Najafi et al. · 2020 · Current Cancer Drug Targets
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors
Ernesto Guccione, Megan Catherine Schwarz, Federico Di Tullio, Slim Mzoughi · 2021 · Current Opinion in Pharmacology