MYC: connecting selective transcriptional control to global RNA production

Molecular Cell Biology

Lodish, H. F. (1986) · Cited by 5,650

Identification of c- MYC as a Target of the APC Pathway

He, T.-C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., & Kinzler, K. W. (1998) · Science · doi:10.1126/science.281.5382.1509 · Cited by 4,566

MYC on the Path to Cancer

Dang, C. V. (2012) · Cell · doi:10.1016/j.cell.2012.03.003 · Cited by 3,390

CpG islands and the regulation of transcription

Deaton, A. M., & Bird, A. (2011) · Genes & Development · doi:10.1101/gad.2037511 · Cited by 3,187

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Land, H., Parada, L. F., & Weinberg, R. A. (1983) · Nature · doi:10.1038/304596a0 · Cited by 2,804

Stat3 as an Oncogene

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The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

Gao, P., Tchernyshyov, I., Chang, T.-C., Lee, Y.-S., Kita, K., Ochi, T., Zeller, K. I., De Marzo, A. M., Van Eyk, J. E., Mendell, J. T., et al. (2009) · Nature · doi:10.1038/nature07823 · Cited by 2,124

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Wise, D. R., DeBerardinis, R. J., Mancuso, A., Sayed, N., Zhang, X.-Y., Pfeiffer, H. K., Nissim, I., Daikhin, E., Yudkoff, M., McMahon, S. B., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810199105 · Cited by 2,001

Oncogenic Pathways in Neurodegenerative Diseases

Varela, L., & García-Rendueles, M. E. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063223 · Cited by 30

N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly

Schweitzer, C. J., Zhang, F., Boyer, A., Valdez, K., Cam, M., & Liang, T. J. (2017) · Journal of Virology · doi:10.1128/jvi.01166-17 · Cited by 28

The transcriptional regulator FUBP1 influences disease outcome in murine and human myeloid leukemia

Hoang, V. T., Verma, D., Godavarthy, P. S., Llavona, P., Steiner, M., Gerlach, K., Michels, B. E., Bohnenberger, H., Wachter, A., Oellerich, T., et al. (2019) · Leukemia · doi:10.1038/s41375-018-0358-8 · Cited by 27

Crosstalk Between MYC and lncRNAs in Hematological Malignancies

Arman, K., & Möröy, T. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.579940 · Cited by 27

c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2

Su, M., Xu, Y., Jiang, X., Huang, M., Zhang, L., Yuan, L., Xu, X.-H., Zhu, Q., Gao, J., Lu, J., et al. (2021) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2021.09.014 · Cited by 28

Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase

Qi, Y., Rezaeian, A.-H., Wang, J., Huang, D., Chen, H., Inuzuka, H., & Wei, W. (2024) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2024.189140 · Cited by 27

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer

Zhao, R., Liu, Y., Wu, C., Li, M., Wei, Y., Niu, W., Yang, J., Fan, S., Xie, Y., Li, H., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.659392 · Cited by 26

L-type amino acid transporter 1 as a target for inflammatory disease and cancer immunotherapy

Hayashi, K., & Anzai, N. (2021) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2021.09.006 · Cited by 29

Characterization of pancreatic glucagon-producing tumors and pituitary gland tumors in transgenic mice overexpressingMYCNinhGFAP-positive cells

Fielitz, K., Althoff, K., Preter, K. D., Nonnekens, J., Ohli, J., Elges, S., Hartmann, W., Klöppel, G., Knösel, T., Schulte, M., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.12766 · Cited by 26

Cancer neuroscience: signaling pathways and new therapeutic strategies for cancer

Zhang, S., Yuan, L., Lin, P., Yang, G., Zhou, X., Jinfu, X., Wu, M., & Huang, Y. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02364-y · Cited by 29

Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw

Loriè, E. P., Stricker, N., Plitta-Michalak, B. P., Chen, I.-P., Volkmer, B., Greinert, R., Jauch, A. S., Boukamp, P., & Rapp, A. W. (2020) · Scientific Reports · doi:10.1038/s41598-020-71315-0 · Cited by 25

A natural product targets BRD4 to inhibit phase separation and gene transcription

Wang, C., Lu, H., Liu, X., Gao, X., Tian, W., Chen, H., Xue, Y., & Zhou, Q. (2021) · iScience · doi:10.1016/j.isci.2021.103719 · Cited by 27

Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response

Xu, M., Lin, L., Ram, B. M., Shriwas, O., Chuang, K., Dai, S., Su, K., Tang, Z., & Dai, C. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.112557 · Cited by 24

E-box binding transcription factors in cancer

Pan, Y., van der Watt, P. J., & Kay, S. A. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1223208 · Cited by 24

E3 Ubiquitin Ligase RLIM Negatively Regulates c-Myc Transcriptional Activity and Restrains Cell Proliferation

Gao, R., Wang, L., Cai, H., Zhu, J., & Yu, L. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164086 · Cited by 25

IBTK contributes to B-cell lymphomagenesis in Eμ-myc transgenic mice conferring resistance to apoptosis

Vecchio, E., Golino, G., Pisano, A., Albano, F., Falcone, C., Ceglia, S., Iaccino, E., Mimmi, S., Fiume, G., Giurato, G., et al. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-1557-6 · Cited by 23

c-Myc downregulation is required for preacinar to acinar maturation and pancreatic homeostasis

Lobo, V. J. S.-A., Fernández, L. C., Pau, E. C. D. S., Richart, L., Cobo, I., Cendrowski, J., Moreno‐Celis, U., del Pozo, N., Megı́as, D., Bréant, B., et al. (2017) · Gut · doi:10.1136/gutjnl-2016-312306 · Cited by 24

A Driver Never Works Alone—Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human Cancer

Grzes, M., Oroń, M., Staszczak, Z., Jaiswar, A., Nowak-Niezgoda, M., & Walerych, D. (2020) · Cancers · doi:10.3390/cancers12061532 · Cited by 24

The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis

Carroll, P. A., Freie, B. W., Cheng, P. F., Kasinathan, S., Gu, H., Hedrich, T., Dowdle, J. A., Venkataramani, V., Ramani, V., Wu, X., et al. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001085 · Cited by 24

c-Myc plays a key role in IFN-γ-induced persistence of Chlamydia trachomatis

Vollmuth, N., Schlicker, L., Guo, Y., Hovhannisyan, P., Janaki‐Raman, S., Kurmasheva, N., Schmitz, W., Schulze, A., Stelzner, K., Rajeeve, K., et al. (2022) · eLife · doi:10.7554/elife.76721 · Cited by 29

RNA cytosine methyltransferase NSUN5 promotes protein synthesis and tumorigenic phenotypes in glioblastoma

Zhou, J., Kong, Y. S., Vincent, K. M., Dieters‐Castator, D. Z., Bukhari, A. B., Glubrecht, D. D., Liu, R., Quilty, D., Findlay, S. D., Huang, X., et al. (2023) · Molecular Oncology · doi:10.1002/1878-0261.13434 · Cited by 25

MYC and AMPK–Save Energy or Die!

Haikala, H. M., Anttila, J. M., & Klefström, J. T. (2017) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2017.00038 · Cited by 25

Functional interplay between c‐Myc and Max in B lymphocyte differentiation

Pérez‐Olivares, M., Trento, A., Rodríguez‐Acebes, S., González‐Acosta, D., Fernández‐Antorán, D., Román‐García, S., Martínez, D., López‐Briones, T., Torroja, C., Carrasco, Y. R., et al. (2018) · EMBO Reports · doi:10.15252/embr.201845770 · Cited by 24

Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway

Fang, X., Xian, X., Jie, T., Mu, H., Shaojun, Z., Ling, Q., Liu, Y., & Xuqun, S. (2021) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2021.04.007 · Cited by 23

Upregulation of KIN17 is associated with non-small cell lung cancer invasiveness

Zhang, Y., Huang, S., Gao, H.-Y., Wu, K., Ouyang, X., Zhu, Z. G., Yu, X., & Zeng, T. (2017) · Oncology Letters · doi:10.3892/ol.2017.5707 · Cited by 23

Oxidative stress enhances the therapeutic action of a respiratory inhibitor in MYC‐driven lymphoma

Donati, G., Nicoli, P., Verrecchia, A., Vallelonga, V., Croci, O., Rodighiero, S., Audano, M., Cassina, L., Ghsein, A., Binelli, G., et al. (2023) · EMBO Molecular Medicine · doi:10.15252/emmm.202216910 · Cited by 21

Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer

Dehno, M. N., Li, Y., Weiher, H., & Schmidt‐Wolf, I. G. H. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093078 · Cited by 22

TIPE3 promotes non-small cell lung cancer progression via the protein kinase B/extracellular signal-regulated kinase 1/2-glycogen synthase kinase 3β-β-catenin/Snail axis

Li, Q., Yu, D., Yu, Z., Gao, Q., Chen, R., Zhou, L., Wang, R., Li, Y., Qian, Y., Zhao, J., et al. (2021) · Translational Lung Cancer Research · doi:10.21037/tlcr-21-147 · Cited by 21

c-Myc deregulation induces mRNA capping enzyme dependency

Lombardi, O., Varshney, D., Phillips, N. M., & Cowling, V. H. (2016) · Oncotarget · doi:10.18632/oncotarget.12701 · Cited by 22

Genomic basis for RNA alterations revealed by whole-genome analyses of 27 cancer typesPreprint

PCAWG Transcriptome Core Group, Calabrese, C., Davidson, N. R., Fonseca, N. A., He, Y., Kahles, A., Lehmann, K.-V., Liu, F., Shiraishi, Y., Soulette, C. M., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/183889 · Cited by 25

Targeting oncogenic transcriptional factor c-myc by oligonucleotide PROTAC for the treatment of hepatocellular carcinoma

Ai, M., Ma, H., He, J., Xu, F., Ming, Y., Ye, Z., Zheng, Q., Luo, D., Yang, K., Li, J., et al. (2024) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2024.116978 · Cited by 23

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

Castell, A., Yan, Q., Fawkner, K., Bazzar, W., Zhang, F., Wickström, M., Alzrigat, M., Franco, M., Krona, C. C., Cameron, D. P., et al. (2022) · Cancer Research Communications · doi:10.1158/2767-9764.crc-21-0019 · Cited by 21

Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation

Zielke, N., Vähärautio, A., Liu, J., Kivioja, T., & Taipale, J. (2022) · Developmental Cell · doi:10.1016/j.devcel.2022.03.018 · Cited by 21

The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex

Papadopoulos, D., Ha, S. A., Fleischhauer, D., Uhl, L., Russell, T. J., Mikičić, I., Schneider, K., Brem, A., Valanju, O. R., Cossa, G., et al. (2024) · Molecular Cell · doi:10.1016/j.molcel.2024.04.007 · Cited by 23

MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21

Liu, L., Xu, F., Chang, C., He, Q., Wu, L., Zhang, Z., & Li, X. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.526 · Cited by 21

Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc

Wang, Y., Ruan, D., Wang, Z., Yu, K., Rong, D., Liu, Z., Wang, F., Hu, J., Jin, Y., Wu, Q., et al. (2022) · Oncogene · doi:10.1038/s41388-022-02515-3 · Cited by 20

Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity

Hepburn, L. A., McHugh, A. T., Fernandes, K., Boag, G., Proby, C. M., Leigh, I. M., & Saville, M. K. (2018) · Oncotarget · doi:10.18632/oncotarget.25196 · Cited by 20

A novel isoform of ATOH8 promotes the metastasis of breast cancer by regulating RhoC

Xu, M., HUANG, S. H., Dong, X., Chen, Y., Li, M., Shi, W., Wang, G., Huang, C., Wang, Q., Liu, Y., et al. (2020) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjaa050 · Cited by 20

WT1-AS/IGF2BP2 Axis Is a Potential Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma According to ceRNA Network Comprehensive Analysis Combined with Experiments

Jia, M., Shi, Y., Xie, Y., Li, W., Deng, J., Fu, D., Bai, J., Ma, Y., Zuberi, Z., Li, J., et al. (2021) · Cells · doi:10.3390/cells11010025 · Cited by 20

LncRNA MNX1-AS1: A novel oncogenic propellant in cancers

Li, T., Zhou, S., Yang, Y. C., Xu, Y., Gong, X., Cheng, Y., & Wang, Y. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.112801 · Cited by 20

Myc inhibition tips the immune balance to promote antitumor immunity

Yang, C., Liu, Y., Hu, Y., Fang, L., Huang, Z., Cui, H., Xie, J., Hong, Y., Chen, W., Xiao, N., et al. (2022) · Cellular and Molecular Immunology · doi:10.1038/s41423-022-00898-7 · Cited by 20

Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling

Zaytseva, O., & Quinn, L. M. (2017) · Genes · doi:10.3390/genes8040118 · Cited by 20

Metabolism in Immune Cell Differentiation and Function

Chapman, N. M., Shrestha, S., & Chi, H. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-94-024-1170-6_1 · Cited by 22

Germinal Centre B Cell Functions and Lymphomagenesis: Circuits Involving MYC and MicroRNAs

Robaina, M. C., Mazzoccoli, L., & Klumb, C. E. (2019) · Cells · doi:10.3390/cells8111365 · Cited by 19

TXNDC9 promotes hepatocellular carcinoma progression by positive regulation of MYC-mediated transcriptional network

Chen, D., Zou, J., Zhao, Z., Tang, X., Deng, Z., Jia, J., & Liu, S. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-1150-4 · Cited by 20

Oncogenic KRAS and the EGFR loop in pancreatic carcinogenesis—A connection to licensing nodes

Schneeweis, C., Wirth, M., Saur, D., Reichert, M., & Schneider, G. (2016) · Small GTPases · doi:10.1080/21541248.2016.1262935 · Cited by 20

HECTD3 promotes gastric cancer progression by mediating the polyubiquitination of c-MYC

Zhang, G., Zhu, Q., Yan, X., Ci, M., Zhao, E., Hou, J., Wan, S., Lü, M., & Cui, H. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-01001-9 · Cited by 19

Epigenetic Mechanisms Underlying Melanoma Resistance to Immune and Targeted Therapies

Rubanov, A., Berico, P., & Hernando, E. (2022) · Cancers · doi:10.3390/cancers14235858 · Cited by 23

MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer

Cichon, M. A., Moruzzi, M. E., Shqau, T. A., Miller, E. E., Mehner, C., Ethier, S. P., Copland, J. A., Radisky, E. S., & Radisky, D. C. (2016) · Cancer Research · doi:10.1158/0008-5472.can-15-3465 · Cited by 19

SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells

Murakami‐Tonami, Y., Ikeda, H., Yamagishi, R., Inayoshi, M., Inagaki, S., Kishida, S., Komata, Y., Köster, J., Takeuchi, I., Kondo, Y., et al. (2016) · Scientific Reports · doi:10.1038/srep31615 · Cited by 19

Zebrafish models of leukemia

He, S., Jing, C., & Look, A. T. (2017) · Methods in cell biology · doi:10.1016/bs.mcb.2016.11.013 · Cited by 20

Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction

Xiong, J., González-Pecchi, V., Qui, M., Ivanov, A. A., Mo, X., Niu, Q., Chen, X. '., Fu, H., & Du, Y. (2018) · Assay and Drug Development Technologies · doi:10.1089/adt.2017.835 · Cited by 19

Exploring MYC relevance to cancer biology from the perspective of cell competition

Paglia, S., Sollazzo, M., Giacomo, S. D., Strocchi, S., & Grifoni, D. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.05.009 · Cited by 18

Insights about MYC and Apoptosis in B-Lymphomagenesis: An Update from Murine Models

Vecchio, E., Fiume, G., Correnti, S., Romano, S., Iaccino, E., Mimmi, S., Maisano, D., Nisticò, N., & Quinto, I. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21124265 · Cited by 19

Focal adhesion kinase activation limits efficacy of Dasatinib in c‐Myc driven hepatocellular carcinoma

Liu, X., Song, X., Zhang, J., Xu, Z., Che, L., Qiao, Y., Pedraza, Y. O., Cigliano, A., Pascale, R. M., Calvisi, D. F., et al. (2018) · Cancer Medicine · doi:10.1002/cam4.1777 · Cited by 18

Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality

Shao, Y., Zielinski, E., Childress, P., Adaway, M., Misra, J., Klunk, A. J., Burr, D. B., Wek, R. C., Mosley, A. L., Liu, Y., et al. (2019) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00343.2018 · Cited by 20

Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model

Huang, L.-Y., Hsieh, Y.-P., Wang, Y., Hwang, D., Jiang, S. S., Huang, W.-T., Chiang, W.-F., Liu, K., & Huang, T. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218171 · Cited by 18

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

Mygland, L., Brinch, S. A., Strand, M. F., Olsen, P. A., Aizenshtadt, A., Lund, K., Solberg, N. T., Lycke, M., Thorvaldsen, T. E., Espada, S., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102807 · Cited by 20

C-Myc-activated long non-coding RNA LINC01050 promotes gastric cancer growth and metastasis by sponging miR-7161-3p to regulate SPZ1 expression

Ji, Z., Tang, T., Chen, M., Dong, B., Sun, W., Wu, N., Chen, H., Feng, Q., Yang, X., Jin, R., et al. (2021) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-021-02155-7 · Cited by 18

The Functional Interaction Between Epstein–Barr Virus and MYC in the Pathogenesis of Burkitt Lymphoma

Solares, S., León, J., & García-Gutiérrez, L. (2024) · Cancers · doi:10.3390/cancers16244212 · Cited by 18

The cohesin complex prevents Myc-induced replication stress

Rohban, S., Cerutti, A., Morelli, M. J., di Fagagna, F. D., & Campaner, S. (2017) · Cell Death and Disease · doi:10.1038/cddis.2017.345 · Cited by 17

MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts

Zhang, F., Zakaria, S. M., Tabor, V., Singh, M., Tronnersjö, S., Goodwin, J., Selivanova, G., Bártek, J., Castell, A., & Larsson, L. (2018) · Cell Cycle · doi:10.1080/15384101.2018.1553339 · Cited by 18

Potential effect of spliceosome inhibition in small cell lung cancer irrespective of the MYC status

Suda, K., Rozeboom, L. M., Yu, H., Ellison, K. E., Rivard, C. J., Mitsudomi, T., & Hirsch, F. R. (2017) · PLoS ONE · doi:10.1371/journal.pone.0172209 · Cited by 17

Differential impacts of charcoal-stripped fetal bovine serum on c-Myc among distinct subtypes of breast cancer cell lines

Liang, Z., Qu, L., & Ma, L. (2020) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2020.03.049 · Cited by 17

Targeted anti-tumor synergistic effects of Myc decoy oligodeoxynucleotides-loaded selenium nanostructure combined with chemoradiotherapy on LNCaP prostate cancer cells

Ghorbani, R., Gharbavi, M., Sharafi, A., Rismani, E., Rezaeejam, H., Mortazavi, Y., & Johari, B. (2023) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.32604/or.2023.044741 · Cited by 17

Brain Plasticity and Cell Competition: Immediate Early Genes Are the Focus

Tregub, P. P., Komleva, Y. K., Kukla, M. V., Сергеевич, А. А., Vetchinova, A. S., Rozanova, N. A., Illarioshkin, S. N., & Salmina, A. B. (2025) · Cells · doi:10.3390/cells14020143 · Cited by 22

MYC Amplification as a Predictive Factor of Complete Pathologic Response to Docetaxel-based Neoadjuvant Chemotherapy for Breast Cancer

Pereira, C. B. L., Leal, M. F., Abdelhay, E. S. F. W., Demachki, S., de Assumpção, P. P., de Souza, M. C., Moreira-Nunes, C. A., Tanaka, A. M. D. S., Smith, M. D. A. C., & Burbano, R. M. R. (2016) · Clinical Breast Cancer · doi:10.1016/j.clbc.2016.12.005 · Cited by 17

Gastric Cancer Cell Lines Have DifferentMYC-Regulated Expression Patterns but Share a Common Core of Altered Genes

Maués, J. H. D. S., Ribeiro, H. F., Pinto, G. R., Lopes, L. D. O., Lamarão, L. M., Pessoa, C. M. F., Moreira-Nunes, C. A., de Carvalho, R. M., de Assumpção, P. P., REY, J. A., et al. (2018) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/2018/5804376 · Cited by 17

Gene-Specific Intron Retention Serves as Molecular Signature that Distinguishes Melanoma from Non-Melanoma Cancer Cells in Greek Patients

Giannopoulou, A. F., Konstantakou, E. G., Velentzas, A. D., Avgeris, S. N., Avgeris, M., Papandreou, N. C., Zoi, I., Filippa, V., Katarachia, S. A., Lampidonis, A. D., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20040937 · Cited by 16

Mnt modulates Myc-driven lymphomagenesis

Campbell, K. J., Vandenberg, C. J., Anstee, N. S., Hurlin, P. J., & Cory, S. (2017) · Cell Death and Differentiation · doi:10.1038/cdd.2017.131 · Cited by 16

Insights into the Links between MYC and 3D Chromatin Structure and Epigenetics Regulation: Implications for Cancer Therapy

Amjadi‐Moheb, F., Paniri, A., & Akhavan‐Niaki, H. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-3613 · Cited by 16

GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival

Petrusca, D. N., Mulcrone, P. L., Macar, D. A., Bishop, R. T., Berdyshev, E. V., Suvannasankha, A., Anderson, J. L., Sun, Q., Auron, P. E., Galson, D. L., et al. (2022) · Cancers · doi:10.3390/cancers14030772 · Cited by 16

Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanomaPreprint

Fluck, M. F. Z., Massó-Vallés, D., Giuntini, F., González-Larreategui, Í., Kaur, J., Casacuberta‐Serra, S., Jauset, T., Martínez-Martín, S., Martín-Fernández, G., del Pozo, E. S., et al. (2023) · Genes & Development · doi:10.1101/gad.350078.122 · Cited by 16

Phosphorylated Toll-like receptor 3 nuclear translocation in cancer cell promotes metastasis and chemoresistance

Wang, Z., Gu, Y. H., Liu, Y., Wang, Z., Chen, X., Wang, H., Zhang, W., Jin, G., & Cao, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02307-7 · Cited by 15

Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence

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Restoration of Mesenchymal RPE by Transcription Factor-Mediated Reprogramming

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Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells

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c-MYC overexpression induces choroid plexus papillomas through a T-cell mediated inflammatory mechanism

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MYC/MAX-Activated LINC00958 Promotes Lung Adenocarcinoma by Oncogenic Transcriptional Reprogramming Through HOXA1 Activation

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The emerging roles of the interaction between m6A modification and c‐Myc in driving tumorigenesis and development

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PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma

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MYCN drives oncogenesis by cooperating with the histone methyltransferase G9a and the WDR5 adaptor to orchestrate global gene transcription

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Gene therapy as a potential tool for treating neuroblastoma—a focused review

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c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

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Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse

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Targeting c-Myc with a novel Peptide Nuclear Delivery Device

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ADA3 regulates normal and tumor mammary epithelial cell proliferation through c-MYC

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Correspondence: Reply to ‘Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα’

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Nuak kinase signaling in development and disease of the central nervous system

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How Driver Oncogenes Shape and Are Shaped by Alternative Splicing Mechanisms in Tumors

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The IMPDH cytoophidium couples metabolism and fetal development in mice

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Combining luteolin and curcumin synergistically suppresses triple-negative breast cancer by regulating IFN and TGF-β signaling pathways

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TXNIP loss expands Myc-dependent transcriptional programs by increasing Myc genomic binding

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Incongruence between transcriptional and vascular pathophysiological cell states

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Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer

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The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein

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Transforming Growth Factor β-Induced Proliferative Arrest Mediated by TRIM26-Dependent TAF7 Degradation and Its Antagonism by MYC

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MYC binding to nascent RNA suppresses innate immune signaling by R-loop-derived RNA-DNA hybrids

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Recent advances in living cell nucleic acid probes based on nanomaterials for early cancer diagnosis

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Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis

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Fine-tuned amplification in cells

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MYC function and regulation in physiological perspective

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Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles

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Measuring MYC-Mediated Metabolism in Tumorigenesis

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