Cited by 729Thyroid Disorders and TreatmentsHormonal and reproductive studiesThyroid and Parathyroid Surgery

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Thyroid hormones and cardiovascular disease

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Jabbar, Avais, Pingitore, Alessandro, Pearce, Simon H. S., Zaman, Azfar, Iervasi, Giorgio, Razvi, Salman·2017·Nature Reviews Cardiology

DOI 10.1038/nrcardio.2016.174

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Abstract

Myocardial and vascular endothelial tissues have receptors for thyroid hormones and are sensitive to changes in the concentrations of circulating thyroid hormones. The importance of thyroid hormones in maintaining cardiovascular homeostasis can be deduced from clinical and experimental data showing that even subtle changes in thyroid hormone concentrations - such as those observed in subclinical hypothyroidism or hyperthyroidism, and low triiodothyronine syndrome - adversely influence the cardiovascular system. Some potential mechanisms linking the two conditions are dyslipidaemia, endothelial dysfunction, blood pressure changes, and direct effects of thyroid hormones on the myocardium. Several interventional trials showed that treatment of subclinical thyroid diseases improves cardiovascular risk factors, which implies potential benefits for reducing cardiovascular events. Over the past 2 decades, accumulating evidence supports the association between abnormal thyroid function at the time of an acute myocardial infarction (MI) and subsequent adverse cardiovascular outcomes. Furthermore, experimental studies showed that thyroid hormones can have an important therapeutic role in reducing infarct size and improving myocardial function after acute MI. In this Review, we summarize the literature on thyroid function in cardiovascular diseases, both as a risk factor as well as in the setting of cardiovascular diseases such as heart failure or acute MI, and outline the effect of thyroid hormone replacement therapy for reducing the risk of cardiovascular disease.

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Heart Disease and Stroke Statistics—2015 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., de Ferranti, S., Després, J.-P., Fullerton, H. J., Howard, V. J., et al. (2015) · Circulation · doi:10.1161/cir.0000000000000152 · Cited by 5,797
Serum TSH, T 4 , and Thyroid Antibodies in the United States Population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III)
Hollowell, J. G., Staehling, N. W., Flanders, W. D., Hannon, W. H., Gunter, E. W., Spencer, C. A., & Braverman, L. E. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.2.489 · Cited by 4,279
Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients
Laurent, S., Boutouyrie, P., Asmar, R., Gautier, I., Laloux, B., Guize, L., Ducimetiere, P., & Benetos, A. (2001) · Hypertension · doi:10.1161/01.hyp.37.5.1236 · Cited by 3,856
The Colorado Thyroid Disease Prevalence Study
Canaris, G. J., Manowitz, N. R., Mayor, G., & Ridgway, E. C. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.4.526 · Cited by 2,824
THE SPECTRUM OF THYROID DISEASE IN A COMMUNITY: THE WHICKHAM SURVEY
Tunbridge, W. M. G., Evered, D. C., Hall, R., Appleton, D. R., BREWIS, M., CLARK, F., Evans, J. G., Young, E. T., Bird, T., & Smith, P. (1977) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1977.tb01340.x · Cited by 2,665
Thyroid hormone and the cardiovascular system.
Klein, I., & Ojamaa, K. (2001) · New England Journal of Medicine · doi:10.1056/nejm200102153440707 · Cited by 2,300
Subclinical Thyroid Disease: Scientific Review and Guidelines for Diagnosis and Management
Surks, M. I., Ortiz, E., Daniels, G. H., Sawin, C. T., Col, N. F., Cobin, R. H., Franklyn, J. A., Hershman, J. M., Burman, K. D., Denke, M. A., et al. (2004) · JAMA · doi:10.1001/jama.291.2.228 · Cited by 1,800
Negative Inotropic Effects of Cytokines on the Heart Mediated by Nitric Oxide
Finkel, M. S., Oddis, C. V., Jacob, T. D., Watkins, S. C., Hattler, B. G. J., & Simmons, R. L. (1992) · Science · doi:10.1126/science.1631560 · Cited by 1,626
The Clinical Significance of Subclinical Thyroid Dysfunction
Biondi, B., & Cooper, D. S. (2008) · Endocrine Reviews · doi:10.1210/er.2006-0043 · Cited by 1,418
Molecular Aspects of Thyroid Hormone Actions
Cheng, S.-Y., Leonard, J. L., & Davis, P. J. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0007 · Cited by 1,384

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Kocher, T. Ueber Kropfexstirpation und ihre Folgen. Arch. Klin. Chir. 29, 254–337 (in German) (1883).

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Shang, J., Zheng, Y., Zhang, M., Li, M., Qiang, W., Sui, J., Guo, H., Shi, B., & He, M. (2024) · Biomedicines · doi:10.3390/biomedicines12102370 · Cited by 2
Impaired sensitivity to thyroid hormones is associated with all-cause and cause-specific mortality among chronic kidney disease patients: results from National Health and Nutrition Examination Survey (NHANES) 2007–2012
Liu, C., Zhu, X., Wang, D., Huang, N., & Chen, W. (2024) · Renal Failure · doi:10.1080/0886022x.2024.2433178 · Cited by 2
Application of Mendelian randomization in thyroid diseases: a review
Li, Z., Wang, R., Liu, L., Jia, Z., Zhou, P., & He, Q. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1472009 · Cited by 2
Effect of thyroid stimulating hormone on the prognosis of coronary heart disease
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Elevated frontal QRS-T angle as a predictor of cardiovascular risk in graves' disease: A comparative study
Wang, Z., Xu, J., Fan, T., Gong, A. J., Li, M., Zhu, N.-J., & Wang, X. (2025) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2025.154040 · Cited by 2
Impaired sensitivity to thyroid hormone was associated with increased continuous metabolic syndrome score
Li, Z., Hu, F., Han, Y., Yao, Y., & Lu, Y. (2025) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2025.104203 · Cited by 2
Elevated mitochondrial DNA copy number in euthyroid individuals with impaired peripheral sensitivity to thyroid hormones
Li, Q., Huang, T., Zhang, D., Li, G., Wei, L., & Liu, J. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1635820 · Cited by 2
Patients with Toxic Nodular Goiter and Graves’ Disease Are at Increased Risk for All-Cause and Cardiovascular Mortality
Pearce, E. N. (2017) · Clinical Thyroidology · doi:10.1089/ct.2017;29.218-220 · Cited by 2
Cardiomegalia associada ao hipotireoidismo clínico
Martinelli, T. C., Braga, R. C., Magalhães, B. A. B. D. M., Musso, S. V., Tonini, R. C., Sasso, R. T., & Brandão, C. D. G. (2019) · Revista de Medicina · doi:10.11606/issn.1679-9836.v98i1p82-86 · Cited by 3
Effects of treatment with haloperidol and clozapine on the plasma concentrations of thyroid hormones in rats
Samadi, A., Ziaee, M., Işıkhan, S. Y., Ulusu, N. N., & Samadi, M. (2020) · Endocrine Regulations · doi:10.2478/enr-2020-0009 · Cited by 2
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Radzhabkadiev, R. М., Vybornaya, K. V., Lavrinenko, C., & Vasil’ev, A. V. (2020) · Human Sport Medicine · doi:10.14529/hsm20s101 · Cited by 2
Pericardial Tamponade and Elevated Serum CA-125 Level in Inadequately Treated Hypothyroidism
Baghal, M., Amrutiya, V., Patel, B., Patel, R., Hernandez, J., Ahmed, M. F., Lo, A., & Gabelman, M. (2021) · Case Reports in Cardiology · doi:10.1155/2021/2666601 · Cited by 2
Alteraciones cardíacas en los pacientes con enfermedad tiroidea
Velandia-Rátiva, A. N., Zarta-Rengifo, L. V., Guerrero-Peña, J. D., Rangel-Castellanos, K. T., Rodríguez, L. J. V., & Ortiz, E. J. R. (2022) · Revista Colombiana de Cardiología · doi:10.24875/rccar.m22000122 · Cited by 2
High triiodothyronine levels induce myocardial hypertrophy via BAFF overexpression
Li, G., Liu, X., Liu, B., Zhong, Y., Gu, Q., Miao, J., Wang, J., Liu, S., & Mao, X. (2022) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17470 · Cited by 2
Ability of the Right Ventricle to Serve as a Systemic Ventricle in Response to the Volume Overload at the Neonatal Stage
Zhou, C., Li, D., Cui, Q., Sun, Q., Hu, Y., Xiao, Y., Jiang, C., Qiu, L., Zhang, H., Ye, L., et al. (2022) · Biology · doi:10.3390/biology11121831 · Cited by 2
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Unexpected Grave’s-induced acute myocardial infarction in a young female, a literature review based on a case report
Naderi, F., Naderi, N., Mousavinezhad, S. M., & Zadeh, A. Z. (2024) · International Journal of Emergency Medicine · doi:10.1186/s12245-024-00695-1 · Cited by 2
Diagnosis, Treatment and Follow up of Primary Hypothyroidism in the Adult. Position Statement of the Portuguese Society of Endocrinology, Diabetes and Metabolism (SPEDM) and the Thyroid Study Group (GET).
Freitas, C., Rodrigues, F., Rocha, G., Simões, H., Miguel, M., & Azevedo, T. (1999) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.26497/na190056 · Cited by 2
Cardiovascular Responses to 5-hydroxytryptamine in Methimazole-induced Hypothyroid Pithed Rats
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Li, H., Zeng, R., Liao, Y.-F., Fu, M., Zhang, H., Wang, L., & Li, Y. (2021) · Current Medical Science · doi:10.1007/s11596-021-2354-x · Cited by 2
Causal relationship between hypothyroidism and the risk of hearing loss: A bidirectional two-sample Mendelian randomization studyPreprint
Zhengxin, Z., & Liu, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-2798037/v1 · Cited by 2
Thyroid Dysfunction and Cardiovascular Disease in Chronic Kidney Disease
Zoccali, C., & Mallamaci, F. (2020) · Springer eBooks · doi:10.1007/978-3-030-36871-5_24 · Cited by 1
Influence of thyroid-stimulating hormone on the recurrence after radiofrequency ablation for atrial fibrillation
Сергіївна, Б. М., Bogun, N., & Shmidt, O. Y. (2021) · EMERGENCY MEDICINE · doi:10.22141/2224-0586.17.4.2021.237735 · Cited by 1
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Kapfhammer, H. (2022) · Springer eBooks · doi:10.1007/978-3-662-65873-4_2 · Cited by 1
Thyroid gland and heart: a cardiologist’s view on an endocrinological pathology. Review
Кondratiuk, V. Y., & Стахова, А. (2023) · Clinical endocrinology and endocrine surgery · doi:10.30978/cees-2023-3-41 · Cited by 1
Subclinical Thyroid Dysfunction and Cardiovascular Disease
Lourenço, I., Correia-Chaves, J., Leite, A. R., Borges‐Canha, M., von Hafe, M., Vale, C., Leite-Moreira, A. F., & Neves, J. S. (2023) · Revista Portuguesa de Endocrinologia Diabetes e Metabolismo · doi:10.26497/ar230029 · Cited by 1
Predictors of High Cardiovascular Risk Among Nonobese Patients with Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease in a Chinese Population [Letter]
Lu, Q., Lin, Y., & Li, Z. (2024) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s464017 · Cited by 1
Ghrelin Hormone Mediates the Ameliorative Effects of Intermittent Fasting on Cardiac Dysfunctions in Experimentally Induced Thyrotoxicosis in Rats
ElSayed, M. H., Shady, E. A. A., Francis, M. M., & Hamid, M. S. A. E. (2024) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093024010137 · Cited by 1
Investigation on thyroid gene network of aged macaques subjected to bone marrow mesenchymal stem cells treatment: Revealed from genic transcriptome analysis
Deng, Y., Li, T., Zheng, H., Zhang, H.-B., Xie, F., Chen, L., & Zhu, G. (2024) · New cell · doi:10.61958/ncgb9882 · Cited by 1
Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat
Rastegar-Moghaddam, S. H., Akbarian, M., Rajabian, A., Alipour, F., Shargh, A. H., Masoomi, R., Ebrahimzadeh‐Bideskan, A., & Hosseini, M. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03593-8 · Cited by 1

Authors: Jabbar, A., Pingitore, A., Pearce, S. H. S., Zaman, A., Iervasi, G., & Razvi, S.
Affiliations: Freeman Hospital (GB)
Istituto di Fisiologia Clinica (IT)
Royal Victoria Infirmary (GB)
Gateshead Health NHS Foundation Trust (GB)
Corresponding author: Razvi, Salman
ORCID: Pingitore, Alessandro
Pearce, Simon H. S.
Zaman, Azfar
Iervasi, Giorgio
Razvi, Salman
Venue: Nature Reviews Cardiology
Publisher: Springer Science and Business Media LLC
Published: 2016-11-04
Volume: 14
Issue: 1
Pages: 39-55
ISSN: 1759-5002 (ISSN-L)
1759-5010
DOI: 10.1038/nrcardio.2016.174
OpenAlex: W2548036931
Cited by: 729
References: 253
Citations by year: 2026: 65 · 2025: 78 · 2024: 89 · 2023: 95 · 2022: 107 · 2021: 87 · 2020: 88 · 2019: 47 · 2018: 42 · 2017: 25
FWCI: 5.53
Type: journal article
Language: en
Open access: green
doi.org
Licence: www.springer.com/tdm (tdm)
Locations: Nature Reviews Cardiology (publishedVersion)
PubMed (publishedVersion)
Newcastle University ePrints (Newcastle Univesity)
Funders: National Institute for Health and Care Research (PB-PG-0610-22139, CDF-2012-05-231)
Medical Research Council (G0500783)
NIHR Academy
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
Keywords: thyroid hormones, cardiovascular disease, heart failure, acute myocardial infarction, subclinical hypothyroidism, hyperthyroidism, low triiodothyronine syndrome, thyroid hormone receptor, endothelial dysfunction, dyslipidemia, blood pressure, thyroid hormone replacement, cardiovascular risk factors, infarct size
MeSH terms: Cardiovascular Diseases, Cardiovascular System, Humans, Hyperthyroidism, Hypothyroidism, Thyroid Hormones, Hormone Replacement Therapy

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