mRNA vaccines — a new era in vaccinology

Pardi, Norbert, Hogan, Michael J., Porter, Frederick W., Weissman, Drew·2018·Nature Reviews Drug Discovery

DOI 10.1038/nrd.2017.243

Cited by (1,011)

Items 201–300 of 1,011

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Savan K. Patel, Margaret M. Billingsley, C. Pritchett Frazee, Xuexiang Han, Kelsey L. Swingle, Jingya Qin, Mohamad‐Gabriel Alameh, Karin Wang, Drew Weissman, Michael J. Mitchell · 2022 · Journal of Controlled Release
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