Trends in the exploitation of novel drug targets

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Items 301–400 of 872

1. Transcriptome Profiling of Dysregulated GPCRs Reveals Overlapping Patterns across Psychiatric Disorders and Age-Disease Interactions
   Roudabeh Vakil Monfared, Wedad Alhassen, Tri Minh Truong, Michael Angelo Maglalang Gonzales, Vincent Vachirakorntong, Siwei Chen, Pierre Baldi, Olivier Civelli, Amal Alachkar · 2021 · Cells
2. NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer
   Raksha R. Bhat, Hariprasad Thangavel, Noor Mazin Abdulkareem, Suhas V. Vasaikar, Carmine De Angelis, Leon Bae, Maria Letizia Cataldo, Sarmistha Nanda, Xiaoyong Fu, Bing Zhang et al. · 2022 · Scientific Reports
3. Prediction of enzyme inhibition and mode of inhibitory action based on calculation of distances between hydrogen bond donor/acceptor groups of the molecule and docking analysis: An application on the discovery of novel effective PTP1B inhibitors
   Phaedra T. Eleftheriou, Anthi Petrou, Athina A. Geronikaki, Κωνσταντίνος Λιάρας, Stavroula Dirnali, M C Maan Anna · 2015 · SAR and QSAR in environmental research
4. Oxytocin receptor behavioral effects and cell types in the bed nucleus of the stria terminalis
   Luo, Pei X., Zakharenkov, Hannah Cortez, Torres, Lisette Y., Rios, Roberto A., Gegenhuber, Bruno, Black, Alexis M., Xu, Christine K., Minie, Vanessa A., Tran, Amy M., Tollkuhn, Jessica et al. · 2022 · Hormones and Behavior
5. Computational Approaches and Resources in Single Amino Acid Substitutions Analysis Toward Clinical Research
   C. George Priya Doss, Chiranjib Chakraborty, Vaishnavi Narayan, D. Thirumal Kumar · 2014 · Advances in protein chemistry and structural biology
6. Signaling through non-membrane nuclear phosphoinositide binding proteins in human health and disease
   Jamal M. Bryant, Raymond D. Blind · 2018 · Journal of Lipid Research
7. Structural Perturbations due to Mutation (H1047R) in Phosphoinositide-3-kinase (PI3Kα) and Its Involvement in Oncogenesis: An in Silico Insight
   Jatin Sharma, Vijay Kumar Bhardwaj, Rituraj Purohit · 2019 · ACS Omega
8. Activatable imaging probes for cancer-linked NAD(P)H:quinone oxidoreductase-1 (NQO1): Advances and future prospects
   Dongdong Su, Xueqian Chen, Yong Zhang, Xueyun Gao · 2020 · TrAC Trends in Analytical Chemistry
9. Beyond traditional pharmacology: new tools and approaches
   Eugenia V. Gurevich, Vsevolod V. Gurevich · 2015 · British Journal of Pharmacology
10. Allosteric modulation of G protein‐coupled receptors by amiloride and its derivatives. Perspectives for drug discovery?
    Arnault Massink, Tasia Amelia, Alex Karamychev, Adriaan P. IJzerman · 2019 · Medicinal Research Reviews
11. Power of Rare Diseases: Found in Translation
    Mark C. Fishman · 2013 · Science Translational Medicine
12. Pilot the pulse: controlling the multiplicity of receptor dynamics
    Andreas Böck, Evi Kostenis, Christian Tränkle, Martin J. Lohse, Klaus Mohr · 2014 · Trends in Pharmacological Sciences
13. An integrative somatic mutation analysis to identify pathways linked with survival outcomes across 19 cancer types
    Sunho Park, Seung-Jun Kim, Donghyeon Yu, Samuel Peña‐Llopis, Jianjiong Gao, Jin Suk Park, Hao Tang, Beibei Chen, Jiwoong Kim, Jessie Norris et al. · 2015 · Bioinformatics
14. Non-canonical modulators of nuclear receptors
    Colin M. Tice, Ya‐Jun Zheng · 2016 · Bioorganic & Medicinal Chemistry Letters
15. Systematic Analysis of Drug Targets Confirms Expression in Disease-Relevant Tissues
    Vinod D. Kumar, Philippe Sanséau, Daniel F. Simola, Mark R. Hurle, Pankaj Agarwal · 2016 · Scientific Reports
16. A novel role of ADGRF1 (GPR110) in promoting cellular quiescence and chemoresistance in human epidermal growth factor receptor 2‐positive breast cancer
    Noor Mazin Abdulkareem, Raksha R. Bhat, Lanfang Qin, Suhas V. Vasaikar, Ambily Gopinathan, Tamika Mitchell, Martin J. Shea, Sarmistha Nanda, Hariprasad Thangavel, Bing Zhang et al. · 2021 · The FASEB Journal
17. Drug Discovery at the Single Molecule Level: Inhibition-in-Solution Assay of Membrane-Reconstituted β-Secretase Using Single-Molecule Imaging
    Anders Gunnarsson, Arjan Snijder, Jennifer Hicks, Jenny Gunnarsson, Fredrik Höök, Stefan Geschwindner · 2015 · Analytical Chemistry
18. Open reading frames associated with cancer in the dark matter of the human genome.
    Ana Paula Delgado, Pamela Brandao, Maria Julia Chapado, Sheilin Hamid, Ramaswamy Narayanan · 2014 · PubMed
19. Advantages and shortcomings of cell-based electrical impedance measurements as a GPCR drug discovery tool
    Jordi Doijen, Tom Van Loy, Bart Landuyt, Walter H. M. L. Luyten, Dominique Schols, Liliane Schoofs · 2019 · Biosensors and Bioelectronics
20. Polypharmacology profiles and phylogenetic analysis of three-finger toxins from mamba venom: Case of aminergic toxins
    Guillaume Blanchet, Guillaume Collet, Gilles Mourier, Nicolas Gilles, Carole Fruchart‐Gaillard, Elodie Marcon, Denis Servent · 2014 · Biochimie
21. Pharmacological characterization of dopamine receptors in the rice striped stem borer, Chilo suppressalis
    Gang Xu, Shun‐Fan Wu, Gui‐Xiang Gu, Ziwen Teng, Gōngyín Yè, Jia Huang · 2017 · Insect Biochemistry and Molecular Biology
22. Direct cell extraction of membrane proteins for structure–function analysis
    Ieva Drulyte, Aspen Rene Gutgsell, Pilar Lloris-Garcerá, Michael Andre Liss, Stefan Geschwindner, Mazdak Radjainia, Jens Frauenfeld, Robin Löving · 2023 · Scientific Reports
23. Molecular drug targets and therapies for Alzheimer’s disease
    Dev Bukhsh Singh, Manish Gupta, Rajesh Kumar Kesharwani, Mamta Sagar, Seema Dwivedi, Krishna Misra · 2014 · Translational Neuroscience
24. G protein-coupled receptors in cardiac biology: old and new receptors
    Simon Richard Foster, Eugeni Roura, Peter Molenaar, Walter G. Thomas · 2015 · Biophysical Reviews
25. Hydrogen Exchange Mass Spectrometry of Proteins at Langmuir Monolayers
    Gregory F. Pirrone, Briana C. Vernon, Michael S. Kent, John R. Engen · 2015 · Analytical Chemistry
26. Effect of Substitution on the Aniline Moiety of the GPR88 Agonist 2-PCCA: Synthesis, Structure–Activity Relationships, and Molecular Modeling Studies
    Chunyang Jin, Ann M. Decker, Danni L. Harris, Bruce E. Blough · 2016 · ACS Chemical Neuroscience
27. Highly Coarse-Grained Representations of Transmembrane Proteins
    Jesper J. Madsen, Anton V. Sinitskiy, Jianing Li, Gregory A. Voth · 2017 · Journal of Chemical Theory and Computation
28. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation
    Daniel O. Kechele, R. Eric Blue, Bailey Zwarycz, Scott T. Espenschied, Amanda T. Mah, Marni B. Siegel, Charles M. Perou, Shengli Ding, Scott T. Magness, P. Kay Lund et al. · 2017 · Journal of Clinical Investigation
29. Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin Receptors
    Cody J. Lensing, Katie T. Freeman, Sathya M. Schnell, Robert Charles Speth, Adam T. Zarth, Carrie Haskell‐Luevano · 2018 · Journal of Medicinal Chemistry
30. Cell penetrating, mitochondria targeting multiply charged DABCO-cyanine dyes
    Atanas Kurutos, Iva Orehovec, Dijana Saftić, Lucija Lulić Horvat, Ivo Crnolatac, Ivo Piantanida, Todor G Deligeorgiev · 2018 · Dyes and Pigments
31. Dynamic genome and transcriptional network‐based biomarkers and drugs: precision in breast cancer therapy
    Ioannis D Kyrochristos, Dimosthenis E. Ziogas, Dimitrios H Roukos · 2018 · Medicinal Research Reviews
32. AlphaFold Meets De Novo Drug Design: Leveraging Structural Protein Information in Multitarget Molecular Generative Models
    Andrius Bernatavicius, Martin Šícho, Antonius P. A. Janssen, Alan Kai Hassen, Mike Preuß, Gerard J. P. van Westen · 2024 · Journal of Chemical Information and Modeling
33. Avenues for the Development of Therapeutics That Target Trace Amine Associated Receptor 1 (TAAR1)
    Gregory M. Miller · 2012 · Journal of Medicinal Chemistry
34. Coordinate-based co-localization-mediated analysis of arrestin clustering upon stimulation of the C–C chemokine receptor 5 with RANTES/CCL5 analogues
    Laura Tarancón‐Díez, Claudia Bönsch, Sebastian Malkusch, Zinnia Truan, Mihaela Munteanu, Mike Heilemann, Oliver Hartley, Ulrike Endesfelder, Alexandre Fürstenberg · 2014 · Histochemistry and Cell Biology
35. Clustered Distribution of Natural Product Leads of Drugs in the Chemical Space as Influenced by the Privileged Target-Sites
    Lin Tao, Feng Zhu, Qin Chu, Cheng Zhang, Shangying Chen, Peng Zhang, Cunlong Zhang, Chunyan Tan, Chunmei Gao, Zhe Chen et al. · 2015 · Scientific Reports
36. Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction
    Jalal Taneera, Israa Mohammed, Abdul Khader Mohammed, Mahmood Yaseen Hachim, Sarah Dhaiban, Abdullah Imadeddin Malek, Pontus Dunér, Noha Mousaad Elemam, Nabil D. Sulaiman, Mawieh A. Hamad et al. · 2019 · Molecular and Cellular Endocrinology
37. Bulk and Single-Cell Next-Generation Sequencing: Individualizing Treatment for Colorectal Cancer
    Ioannis D Kyrochristos, Dimosthenis E. Ziogas, ANNA C. GOUSSIA, Georgios K. Glantzounis, Dimitrios H Roukos · 2019 · Cancers
38. The role of G protein-coupled receptor in neutrophil dysfunction during sepsis-induced acute respiratory distress syndrome
    Yi Wang, Cheng‐long Zhu, Peng Li, Qiang Liu, Hui-ru Li, Chang-meng Yu, Xiaoming Deng, Jiafeng Wang · 2023 · Frontiers in Immunology
39. Can medical genetics and evolutionary biology inspire drug target identification?
    Zhongyi Wang, Liang-Yu Fu, Hongyu Zhang · 2011 · Trends in Molecular Medicine
40. Biosensor‐based affinities and binding kinetics of small molecule antagonists to the adenosine A2Areceptor reconstituted in HDL like particles
    Elena Segala, James C. Errey, Cédric Fiez-Vandal, Andrei Zhukov, Robert M. Cooke · 2015 · FEBS Letters
41. Structure‐function studies with G protein‐coupled receptors as a paradigm for improving drug discovery and development of therapeutics
    Patrick M. McNeely, Andrea N. Naranjo, Anne Skaja Robinson · 2012 · Biotechnology Journal
42. Evidence-Based Precision Oncology with the Cancer Targetome
    Aurora Blucher, Gabrielle Choonoo, Molly F Kulesz-Martin, Guanming Wu, Shannon K. McWeeney · 2017 · Trends in Pharmacological Sciences
43. GPCRs profiling and identification of GPR110 as a potential new target in HER2+ breast cancer
    Raksha R. Bhat, Puja Yadav, Debashish Sahay, Dharmendra K. Bhargava, Chad J. Creighton, Sahar Yazdanfard, Ahmed Al-Rawi, Vikas Yadav, Lanfang Qin, Sarmistha Nanda et al. · 2018 · Breast Cancer Research and Treatment
44. Ellagic acid and human cancers: a systems pharmacology and docking study to identify principal hub genes and main mechanisms of action
    Hamid Cheshomi, Ahmad Reza Bahrami, Maryam Moghaddam Matin · 2020 · Molecular Diversity
45. GPCRs in context: sexual dimorphism in the cardiovascular system
    Margaret A. Mouat, James L. J. Coleman, Nicola J. Smith · 2018 · British Journal of Pharmacology
46. Assessing the public landscape of clinical-stage pharmaceuticals through freely available online databases
    Rebekah H. Griesenauer, Constantino Schillebeeckx, Michael S. Kinch · 2019 · Drug Discovery Today
47. Identification of Active Compounds of Mahuang Fuzi Xixin Decoction and Their Mechanisms of Action by LC‐MS/MS and Network Pharmacology
    Xiao Liang, Chang‐Shun Liu, Ting Xia, Qingfa Tang, Xiaomei Tan · 2020 · Evidence-based Complementary and Alternative Medicine
48. Using GPCRs as Molecular Beacons to Target Ovarian Cancer with Nanomedicines
    Riya Khetan, Cintya Dharmayanti, Todd A. Gillam, Eric Kübler, Manuela Klingler‐Hoffmann, Carmela Ricciardelli, Martin Klaus Oehler, Anton Blencowe, Sanjay Garg, Hugo Albrecht · 2022 · Cancers
49. Combinatorial synthesis enables scalable designer detergents for membrane protein studies
    Leonhard Hagen Urner, Armin Ariamajd, Alex Weikum · 2022 · Chemical Science
50. Mining the Potential of Label-Free Biosensors for Seven-Transmembrane Receptor Drug Discovery
    Magalie Rocheville, Julio J. Martin, Jeff C. Jerman, Evi Kostenis · 2013 · Progress in molecular biology and translational science
51. The expanding role of immunopharmacology: IUPHAR Review 16
    Ekaterini Tiligada, Masaru Ishii, Carlo Riccardi, Michael Spedding, Hans‐Uwe Simon, Mauro Martins Teixeira, Mario Landys Chovel Cuervo, Stephen T. Holgate, Francesca Levi‐Schaffer · 2015 · British Journal of Pharmacology
52. Systems biology‐embedded target validation: improving efficacy in drug discovery
    Drieke Vandamme, Benedikt Minke, William Fitzmaurice, Boris Ν. Kholodenko, Walter Kölch · 2013 · WIREs Systems Biology and Medicine
53. Integral membrane pyrophosphatases: a novel drug target for human pathogens?
    Nita R. Shah, Keni Vidilaseris, Henri Xhaard, Adrian Goldman · 2016 · AIMS Biophysics
54. Docking analysis targeted to the whole enzyme: an application to the prediction of inhibition of PTP1B by thiomorpholine and thiazolyl derivatives
    C. A. Ganou, Phaedra T. Eleftheriou, Panagiotis Theodosis‐Nobelos, M. Fesatidou, Athina A. Geronikaki, Theodore S. Lialiaris, Eleni A. Rekka · 2018 · SAR and QSAR in environmental research
55. Brain Cancer Drug Discovery: Clinical Trials, Drug Classes, Targets, and Combinatorial Therapies
    Aleksandr V. Sokolov, Samira A. Dostdar, Misty M. Attwood, Aleksandra A. Krasilnikova, Anastasia A. Ilina, Amina Sh. Nabieva, Anna A. Lisitsyna, Vladimir N. Chubarev, Vadim V. Tarasov, Helgi B. Schiöth · 2021 · Pharmacological Reviews
56. Ayurveda – Opportunities for Developing Safe and Effective Treatment Choices for the Future
    Pratip Kumar Debnath, Subhadip Banerjee, Parikshit Debnath, Achintya Mitra, Pulok Kumar Mukherjee · 2015 · Elsevier eBooks
57. Deciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin Action
    Jingchun Sun, Min Zhao, Peilin Jia, Wang Lily, Yonghui Wu, Iverson Carissa, Yubo Zhou, Erica Bowton, Dan M. Roden, Joshua C. Denny et al. · 2015 · PLoS Computational Biology
58. GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17
    Subbroto Kumar Saha, Hye Yeon Choi, Gwang‐Mo Yang, Polash Kumar Biswas, Kyeongseok Kim, Geun‐Ho Kang, Minchan Gil, Ssang‐Goo Cho · 2020 · Molecular Therapy — Oncolytics
59. Withaferin A Promotes White Adipose Browning and Prevents Obesity Through Sympathetic Nerve–Activated Prdm16-FATP1 Axis
    Bingbing Guo, Jiarui Liu, Bingwei Wang, Chenyu Zhang, Zhijie Su, Miao Zhao, Lihua Qin, Weiguang Zhang, Ruimao Zheng · 2021 · Diabetes
60. The Effects of Statins on Cognitive Performance Are Mediated by Low-Density Lipoprotein, C-Reactive Protein, and Blood Glucose Concentrations
    Mélissa Gentreau, Gull Rukh, Maud Miguet, Laura E. Clemensson, Ahmed M. Alsehli, Olga E. Titova, Helgi B. Schiöth · 2023 · The Journals of Gerontology Series A
61. A Decade of the Human Genome Sequence—How Does the Medicinal Chemist Benefit?
    Andreas Brunschweiger, Jonathan Hall · 2011 · ChemMedChem
62. Circulating Tumor DNA: New Horizons for Improving Cancer Treatment
    Georgios D. Lianos, Alberto Mangano, William Chi Shing Cho, Gianlorenzo Dionigi, Dimitrios H Roukos · 2015 · Future Oncology
63. Cross-saturation and transferred cross-saturation experiments
    Takumi Ueda, Koh Takeuchi, N. Nishida, Pavlos Stampoulis, Yutaka Kofuku, Masanori Osawa, Ichio Shimada · 2014 · Quarterly Reviews of Biophysics
64. Signal transduction mechanism of biased ligands at histamine H2 receptors
    Natalia Alonso, Federico Monczor, Emiliana Echeverría, Carlos Alberto Davio, Carina Shayo, Natalia Fernández · 2014 · Biochemical Journal
65. Technological advances for interrogating the human kinome
    Akanksha Baharani, Brett Trost, ANTHONY J. KUSALIK, Scott Napper · 2017 · Biochemical Society Transactions
66. Quantification of Pharmaceutical Related Biological Activity in Effluents from Wastewater Treatment Plants in UK and Japan
    Han Zhang, Masaru Ihara, Seiya Hanamoto, Norihide Nakada, Monika D. Jürgens, Andrew C. Johnson, Hiroaki Tanaka · 2018 · Environmental Science & Technology
67. Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy
    Patricio Iturriaga‐Vásquez, Jans H. Alzate‐Morales, Isabel Bermúdez, Rodrigo Varas, Miguel Iván Reyes-Parada · 2015 · Pharmacological Research
68. Three-Dimensional Biologically Relevant Spectrum (BRS-3D): Shape Similarity Profile Based on PDB Ligands as Molecular Descriptors
    Ben Hu, Zhengkun Kuang, Shiyu Feng, Dong Wang, Song-Bing He, Kong De · 2016 · Molecules
69. Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin
    Xiao‐Chen Yuan, Ya‐Xiong Tao · 2022 · Biomolecules
70. Determining the Secondary Structure of Membrane Proteins and Peptides Via Electron Spin Echo Envelope Modulation (ESEEM) Spectroscopy
    Lishan Liu, Daniel J. Mayo, Indra D. Sahu, Andy Zhou, Rongfu Zhang, Robert M. McCarrick, Gary A. Lorigan · 2015 · Methods in enzymology on CD-ROM/Methods in enzymology
71. Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery
    Fang Ye · 2015 · Expert Opinion on Drug Discovery
72. Insights into the molecular mechanisms of action of bioportides: a strategy to target protein-protein interactions
    John Howl, Sarah Jones · 2015 · Expert Reviews in Molecular Medicine
73. Allosteric Modulation of Chemoattractant Receptors
    Marcello Allegretti, Maria Candida Cesta, Massimo Locati · 2016 · Frontiers in Immunology
74. An Alternative Thiol-Reactive Dye to Analyze Ligand Interactions with the Chemokine Receptor CXCR2 Using a New Thermal Shift Assay Format
    Christian Bergsdorf, Cédric Fiez-Vandal, David A. Sykes, Pascal Bernet, Sonia Aussenac, Steven J. Charlton, Ulrich Schopfer, Johannes Ottl, Myriam Duckely · 2015 · SLAS DISCOVERY
75. Protection of Primary Dopaminergic Midbrain Neurons by GPR139 Agonists Supports Different Mechanisms of MPP+ and Rotenone Toxicity
    Kirsten Bayer Andersen, Jens Leander Johansen, Morten Hentzer, Garrick Paul Smith, Gunnar P.H. Dietz · 2016 · Frontiers in Cellular Neuroscience
76. Nanoyeast and Other Cell Envelope Compositions for Protein Studies and Biosensor Applications
    Yadveer S. Grewal, Muhammad J. A. Shiddiky, Stephen M. Mahler, Gerard A. Cangelosi, Matt Trau · 2016 · ACS Applied Materials & Interfaces
77. Fluorescent Inhibitors as Tools To Characterize Enzymes: Case Study of the Lipid Kinase Phosphatidylinositol 4-Kinase IIIβ (PI4KB)
    Jana Humpolíčková, Ivana Mejdrová, Marika Matoušová, Radim Nencka, Evžen Bouřa · 2016 · Journal of Medicinal Chemistry
78. Quantitative image cytometry for analyzing intracellular trafficking of G protein-coupled receptors on a chemical-trapping single cell array
    Modong Tan, Satoshi Yamaguchi, Shinya Yamahira, Motonao Nakamura, Teruyuki Nagamune · 2017 · Lab on a Chip
79. ALLO : A tool to discriminate and prioritize allosteric pockets
    Rahmad Akbar, Volkhard Helms · 2017 · Chemical Biology & Drug Design
80. Innovative Computer-Aided Methods for the Discovery of New Kinase Ligands
    Areej Abuhammad, Mutasem O. Taha · 2016 · Future Medicinal Chemistry
81. Structural heterogeneity of the μ-opioid receptor’s conformational ensemble in the apo state
    D.M. Sena, Xiaojing Cong, Alejandro Giorgetti, Achim Kless, Paolo Carloni · 2017 · Scientific Reports
82. Deciphering complexity of GPCR signaling and modulation: implications and perspectives for drug discovery
    Cláudio M. Costa-Neto, Lucas T. Parreiras‐e‐Silva · 2025 · Clinical Science
83. Genomic variant annotation workflow for clinical applications
    Thomas Thurnherr, Franziska Singer, Daniel Johannes Stekhoven, Niko Beerenwinkel · 2016 · F1000Research
84. NF-κB and EGFR participate in S1PR3-mediated human renal cell carcinomas progression
    Yali Yan, Gegentuya Bao, Jingyuan Pei, Ying Cao, Chen‐Yu Zhang, Pengfei Zhao, Yantao Zhang, Alatangaole Damirin · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
85. Predicting GPCR Promiscuity Using Binding Site Features
    Anat Levit, Thijs Beuming, Goran Krilov, Woody Sherman, Masha Y. Niv · 2013 · Journal of Chemical Information and Modeling
86. Photoaffinity Labeling of the Human A 2A Adenosine Receptor and Cross-link Position Analysis by Mass Spectrometry
    Hideyuki Muranaka, Takaki Momose, Chiaki Handa, Tomonaga Ozawa · 2017 · ACS Medicinal Chemistry Letters
87. Auto-induction of Pichia pastoris AOX1 promoter for membrane protein expression
    Jonas Y. Lee, Hao Chen, Alan Liu, Benjamin M. Alba, Ai Ching Lim · 2017 · Protein Expression and Purification
88. Impedance-Based Assays Along the Life Span of Adherent Mammalian Cells In Vitro: From Initial Adhesion to Cell Death
    Judith A. Stolwijk, Joachim Wegener · 2019 · Bioanalytical reviews
89. DirectMX – One-Step Reconstitution of Membrane Proteins From Crude Cell Membranes Into Salipro Nanoparticles
    Pilar Lloris-Garcerá, Stefan Klinter, Liuhong Chen, Michael J. Skynner, Robin Löving, Jens Frauenfeld · 2020 · Frontiers in Bioengineering and Biotechnology
90. Bioinformatics and Biomedical Engineering
    Francisco Manuel Ortuño, Ignacio Rojas · 2015 · Lecture notes in computer science
91. Drug reprofiling history and potential therapies against Parkinson’s disease
    Komal Latif, Aman Ullah, Anastasiia D. Shkodina, Dmytro I. Boiko, Zakia Rafique, Badrah Saeed Ali Alghamdi, Mohamed A. Alfaleh, Ghulam Md Ashraf · 2022 · Frontiers in Pharmacology
92. Unbundling the impact of current and future competition on cooperation in coopetition projects for innovation
    Mohammad Saleh Farazi, Paul Chiambaretto, Anne‐Sophie Fernandez, Shanthi Gopalakrishnan · 2024 · Research Policy
93. Fitting the complexity of GPCRs modulation into simple hypotheses of ligand design
    Chiara Custodi, Roberto Nuti, Tudor Ionel Oprea, Antonio Macchiarulo · 2012 · Journal of Molecular Graphics and Modelling
94. Forward Chemical Genetics in Yeast for Discovery of Chemical Probes Targeting Metabolism
    Robert St.Onge, Ulrich Schlecht, Curt Scharfe, Marie Evangelista · 2012 · Molecules
95. Chemosensorische Ensembles zur Echtzeitdetektion von Transportprozessen durch Biomembranen
    Garima Ghale, Adrienne Gallant Lanctôt, Hannah T. Kreissl, Maik H. Jacob, Helge Weingart, Mathias Winterhalter, Werner M. Nau · 2014 · Angewandte Chemie
96. Conserved disulfide bond is not essential for the adenosine A2A receptor: Extracellular cysteines influence receptor distribution within the cell and ligand-binding recognition
    Andrea N. Naranjo, Amy Chevalier, Gregory D. Cousins, Esther Ayettey, Emily C. McCusker, Carola Wenk, Anne Skaja Robinson · 2014 · Biochimica et Biophysica Acta (BBA) - Biomembranes
97. Identification of a Potential Target of Capsaicin by Computational Target Fishing
    Xuan-Yi Ye, Qing‐Zhi Ling, Chen Shao-jun · 2015 · Evidence-based Complementary and Alternative Medicine
98. Allosteric sodium binding cavity in GPR3: a novel player in modulation of Aβ production
    Stefano Capaldi, Eda Suku, Martina Antolini, Mattia Di Giacobbe, Alejandro Giorgetti, Mario Buffelli · 2018 · Scientific Reports
99. Drug Discovery and Development: An Insight into Pharmacovigilance
    Prashansa Agrawal · 2016 · Journal of Pharmacovigilance
100. Antiviral Effects of Inhibiting Host Gene Expression
     Ralph A. Tripp, Mark Tompkins · 2014 · Current topics in microbiology and immunology