Cited by 746Sleep and related disordersObstructive Sleep Apnea ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

The DOI matches its Crossref record; 192 of the 192 references it cites were found in a registry or an index.

Insomnia disorder

Morin, Charles M., Drake, Christopher L., Harvey, Allison G., Krystal, Andrew D., Manber, Rachel, Riemann, Dieter, Spiegelhalder, Kai·2015·Nature Reviews Disease Primers

DOI 10.1038/nrdp.2015.26

Open this paper in CoChat — free account

Abstract

Insomnia disorder affects a large proportion of the population on a situational, recurrent or chronic basis and is among the most common complaints in medical practice. The disorder is predominantly characterized by dissatisfaction with sleep duration or quality and difficulties initiating or maintaining sleep, along with substantial distress and impairments of daytime functioning. It can present as the chief complaint or, more often, co-occurs with other medical or psychiatric disorders, such as pain and depression. Persistent insomnia has been linked with adverse long-term health outcomes, including diminished quality of life and physical and psychological morbidity. Despite its high prevalence and burden, the aetiology and pathophysiology of insomnia is poorly understood. In the past decade, important changes in classification and diagnostic paradigms have instigated a move from a purely symptom-based conceptualization to the recognition of insomnia as a disorder in its own right. These changes have been paralleled by key advances in therapy, with generic pharmacological and psychological interventions being increasingly replaced by approaches that have sleep-specific and insomnia-specific therapeutic targets. Psychological and pharmacological therapies effectively reduce the time it takes to fall asleep and the time spent awake after sleep onset, and produce a modest increase in total sleep time; these are outcomes that correlate with improvements in daytime functioning. Despite this progress, several challenges remain, including the need to improve our knowledge of the mechanisms that underlie insomnia and to develop more cost-effective, efficient and accessible therapies.

Integrity signals

Registry

Crossref · 10.1038/nrdp.2015.26

Cites

192 of 192 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
Validation of the Insomnia Severity Index as an outcome measure for insomnia research
Bastien, C. (2001) · Sleep Medicine · doi:10.1016/s1389-9457(00)00065-4 · Cited by 8,067
Mindfulness: A proposed operational definition.
Bishop, S. R., Lau, M., Shapiro, S., Carlson, L., Anderson, N. D., Carmody, J., Segal, Z. V., Abbey, S., Speca, M., Velting, D., et al. (2004) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.bph077 · Cited by 7,234
Principles and Practice of Sleep Medicine
Kryger, M. H., Roth, T. G., & Dement, W. C. (2011) · Elsevier eBooks · doi:10.1016/c2009-0-59875-3 · Cited by 5,118
The Insomnia Severity Index: Psychometric Indicators to Detect Insomnia Cases and Evaluate Treatment Response
Morin, C. M., Belleville, G., Bélanger, L., & Ivers, H. (2011) · Sleep · doi:10.1093/sleep/34.5.601 · Cited by 4,620
Self-citation
Epidemiology of insomnia: what we know and what we still need to learn
Ohayon, M. M. (2002) · Sleep Medicine Reviews · doi:10.1053/smrv.2002.0186 · Cited by 3,743
Meta-Analysis of Quantitative Sleep Parameters From Childhood to Old Age in Healthy Individuals: Developing Normative Sleep Values Across the Human Lifespan
Ohayon, M. M., Carskadon, M. A., Guilleminault, C., & Vitiello, M. V. (2004) · Sleep · doi:10.1093/sleep/27.7.1255 · Cited by 3,349
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804
Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies
Baglioni, C., Battagliese, G., Feige, B., Spiegelhalder, K., Nissen, C., Voderholzer, U., Lombardo, C., & Riemann, D. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.01.011 · Cited by 2,779
Self-citation

Flagged first, then by citations

Show all 191 references

Research works printed but not linked: 5

Riemann, D. et al. REM sleep instability — a new pathway for insomnia? Pharmacopsychiatry 45, 167–176 (2012).
Hayes, S. C., Strosahl, K. D. & Wilson, K. G. Acceptance and Commitment Therapy, Second Edition: The Process and Practice of Mindful Change (Guilford Press, 2011).
Spielman, A. J., Saskin, P. & Thorpy, M. J. Treatment of chronic insomnia by restriction of time in bed. Sleep 10, 45–56 (1987).
Léger, D., Massuel, M.-A. & Metlaine, A. Professional correlates of insomnia. Sleep 29, 171–178 (2006).
Katz, D. A. & McHorney, C. A. The relationship between insomnia and health-related quality of life in patients with chronic illness. J. Fam. Pract. 51, 229–235 (2002).

Sorted by citations

Items 401–500 of 744

Association of Gut Microbiota With Objective Sleep Measures in Women With and Without Human Immunodeficiency Virus Infection: The IDOze Study
Zhang, Y., Lin, C. L., Weber, K. M., Xing, J., Peters, B. A., Sollecito, C. C., Grassi, E., Wiek, F., Xue, X., Seaberg, E. C., et al. (2023) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiad371 · Cited by 6
Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials of the efficacy of lemborexant
Lenderking, W. R., Savva, Y., Atkinson, M. J., Campbell, R., Chabot, I., Moline, M. L., Meier, G., & Morin, C. M. (2024) · Journal of Patient-Reported Outcomes · doi:10.1186/s41687-024-00744-6 · Cited by 6
Self-citation
Smartphone application‐delivered cognitive behavioural therapy for insomnia with telephone support for insomnia disorder compared to a waitlist control: a randomised clinical trial
Jansson‐Fröjmark, M., & Sunnhed, R. (2024) · Journal of Sleep Research · doi:10.1111/jsr.14363 · Cited by 6
Insomnia and its treatments—trend analysis and publication profile of randomized clinical trials
Kakazu, V. A., Assis, M., Bacelar, A., Bezerra, A. G., Ciutti, G. L. R., Conway, S. G., Galduróz, J. C. F., Drager, L. F., Khoury, M. P., Leite, I. P. A., et al. (2024) · npj Biological Timing and Sleep · doi:10.1038/s44323-024-00014-0 · Cited by 6
Gene expression is associated with brain function of insomnia disorder, rather than brain structure
Zhang, H., Sun, H., Li, J., Lv, Z., Tian, Y., & Lei, X. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111209 · Cited by 6
Association between household air pollution due to solid fuel use and sleep problems among older adults in India
Rani, R., Selvamani, Y., & Perianayagam, A. (2025) · Journal of Biosocial Science · doi:10.1017/s0021932024000403 · Cited by 6
Chronic insomnia – beyond the symptom of insufficient sleep
Georgiev, T., Draganova, A. I., Avramov, K., & Terziyski, K. V. (2025) · Folia Medica · doi:10.3897/folmed.67.e151493 · Cited by 9
Effectiveness and safety of fire-needle moxibustion on insomnia
Liu, C., Chen, Z., Li, T., Yang, Z., Zhang, Q., Yin, J., Zhou, P., Fu, W., & Chen, B. (2019) · Medicine · doi:10.1097/md.0000000000014509 · Cited by 6
KEJADIAN INSOMNIA DI MASA PEMBATASAN SOSIAL SKALA BESAR (PSBB) JAKARTA AKIBAT PANDEMIK COVID-19
Firmansyah, Y., Ernawati, E., Hendsun, H., & Buntara, I. (2021) · HEARTY · doi:10.32832/hearty.v8i2.4567 · Cited by 6
Orofacial Pain and Snoring/Obstructive Sleep Apnea in Individuals with Head and Neck Cancer: A Critical Review
Fabbro, C. D., Harris, P., Dufresne, E., Babiloni, A. H., Mayer, P., Bahig, H., Filion, É., Nguyen, F., Ghannoum, J., Schmittbuhl, M., et al. (2022) · Journal of Oral & Facial Pain and Headache · doi:10.11607/ofph.3176 · Cited by 6
Real-World-Evidenz für den Einsatz von digitaler kognitiver Verhaltenstherapie bei Insomnie in der Regelversorgung
Maurer, L., Aust, F., & Lorenz, N. (2023) · Somnologie - Schlafforschung und Schlafmedizin · doi:10.1007/s11818-023-00422-7 · Cited by 6
The role of benzodiazepines in common conditions: a narrative review focusing on lormetazepam
Pallanti, S. (2024) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000529 · Cited by 7
Latent profile of the insomnia severity index: A longitudinal study
Wang, S., Jülich, S. T., & Lei, X. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.02.027 · Cited by 8
Static and temporal dynamic alterations of local functional connectivity in chronic insomnia
Li, J., Li, S., Zeng, S., Wang, X., Liu, M., Xu, G., & Ma, X. (2024) · Brain Imaging and Behavior · doi:10.1007/s11682-024-00928-0 · Cited by 6
Sleep Pharmacogenetics: The Promise of Precision Medicine.
Krystal, A., & Prather, A. (2019) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2019.05.003 · Cited by 6
Self-citation
Age-Related Differences in Mood, Diabetes-Related Distress, and Functional Outcomes in Adults With Type 2 Diabetes Mellitus and Comorbid Obstructive Sleep Apnea and Insomnia
Jeon, B., Sereika, S. M., Callan, J. A., Luyster, F. S., DiNardo, M. M., & Chasens, E. R. (2020) · The Science of Diabetes Self-Management and Care · doi:10.1177/0145721720958396 · Cited by 8
Effects of Tai Chi and cognitive behavioral therapy for insomnia on improving sleep in older adults: Study protocol for a non-inferiority trial
Yu, D. J., Yu, A. P., Li, S. X., Chan, R. N. Y., Fong, D., Chan, D. K. C., Hui, S. S., Chung, K., Woo, J., Wang, C., et al. (2022) · Journal of Exercise Science & Fitness · doi:10.1016/j.jesf.2022.10.012 · Cited by 7
The benefit and neural mechanisms of computerized inhibitory control training for insomnia with short sleep duration phenotype: a rs-fMRI study
Zhang, H., Lv, Z., Chen, H., Tang, Z., & Lei, X. (2025) · Behaviour Research and Therapy · doi:10.1016/j.brat.2025.104776 · Cited by 5
Redefining insomnia: from neural dysregulation to personalized therapeutics
Arias-Carrión, Ó. (2025) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2025.2564709 · Cited by 5
The efficacy and safety of repetitive transcranial magnetic stimulation for comorbid chronic low back pain and insomnia: A randomized, double-blind, sham-controlled pilot trial
Chang, J. R., Sun, E. R., Jin, M., Lin, L. G., Li, S. X., Lee, J. L., Huang, F. F., Kwan, R. L., Zheng, D. K. Y., Samartzis, D., et al. (2025) · Journal of Pain · doi:10.1016/j.jpain.2025.106180 · Cited by 7
The association between periodontal disease, dementia, and mild cognitive Impairment: Assessing the contribution of sleep disturbances and sleep disorders
Babiloni, A. H., Baril, A., Sangalli, L., Lavigne, G. J., Kabir, R., Gargouri, N., & Fabbro, C. D. (2025) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2025.102112 · Cited by 6
Clinical efficacy of modified suanzaoren decoction compared to esazolam tablets in the treatment of chronic insomnia disorder
Yao, P., Guo, X., Guo, Z., Lin, W., Liu, M., Chen, M., Li, J., Cui, L., & Lv, D. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1533652 · Cited by 5
UK Medical Cannabis Registry: A clinical outcomes analysis for insomnia
Aggarwal, A., Erridge, S., Cowley, I., Evans, L., Varadpande, M., Clarke, E., McLachlan, K., Coomber, R., Rucker, J., Weatherall, M. W., et al. (2025) · PLOS mental health. · doi:10.1371/journal.pmen.0000390 · Cited by 5
Molecular modeling technology studies of novel pyrazoylethylbenzamide derivatives as selective orexin receptor 1 antagonists
Li, Q., Zhang, C., & Ren, Y. (2019) · Journal of the Taiwan Institute of Chemical Engineers · doi:10.1016/j.jtice.2019.03.018 · Cited by 5
Associations Between Sleep and Personality Factors Among Patients Living With Coronary Artery Disease
Kjellsdotter, A., Edéll‐Gustafsson, U., & Yngman‐Uhlin, P. (2020) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000691 · Cited by 5
Insomnia is frequent in amyotrophic lateral sclerosis at the time of diagnosis
Choquer, M., Blasco, H., Plantier, L., Beltran, S., Bakkouche, S. E., Corcia, P., & Limousin, N. (2020) · Sleep and Biological Rhythms · doi:10.1007/s41105-020-00296-4 · Cited by 5
Evidence of Genetic Overlap Between Circadian Preference and Brain White Matter Microstructure
García‐Marín, L. M., Alcauter, S., Campos, A. I., Mulcahy, A., Kho, P. F., Cuéllar-Partida, G., & Rentería, M. E. (2021) · Twin Research and Human Genetics · doi:10.1017/thg.2021.4 · Cited by 5
Daridorexant for insomnia disorder
Spiegelhalder, K., Feige, B., Riemann, D., & Kyle, S. D. (2022) · The Lancet Neurology · doi:10.1016/s1474-4422(22)00007-2 · Cited by 5
Self-citation
Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia
Alsehli, A. M., Rukh, G., Clemensson, L. E., Ciuculete, D. M., Tan, X. W., Al-Sabri, M. H., Williams, M. J., Benedict, C., & Schiöth, H. B. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/5039 · Cited by 5
Can You Sleep? – Effect of Retrospective Recall of Child Maltreatment on Sleep Parameters and the Mediating Role of Psychological Distress Among Students of Two German Universities
Jarczok, M., Lange, S., Domhardt, M., Baumeister, H., & Jud, A. (2022) · Nature and Science of Sleep · doi:10.2147/nss.s360610 · Cited by 5
Factors Associated with Prescriptions for an Orexin Receptor Antagonist Among Japanese Patients with Insomnia: Analysis of a Nationwide Japanese Claims Database
Okuda, S., Qureshi, Z. P., Yanagida, Y., Ito, C., Homma, Y., & Tokita, S. (2023) · Drugs - Real World Outcomes · doi:10.1007/s40801-023-00356-4 · Cited by 5
Prevalence and influencing factors of sleep disturbance among medical students under the COVID-19 pandemic
Wang, S., Luo, G.-S., Zhang, X., Jing, Y.-F., Zaimina, Yao, C., Li, M.-J., Chen, H.-L., & Li, J. (2023) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-023-01707-6 · Cited by 4
Effect of Centella asiatica ethanol extract on zebrafish larvae (Danio rerio) insomnia model through inhibition of Orexin, ERK, Akt and p38
Afif, Z., Santoso, M. I. E., Nurdiana, N., Khotimah, H., Satriotomo, I., Kurniawan, S. N., Sujuti, H., Iskandar, D. S., & Hakimah, A. (2024) · F1000Research · doi:10.12688/f1000research.141064.1 · Cited by 5
Insomnia among college students: A bibliometric analysis from 2003 to 2022
Yang, M., & Li, L. (2024) · Medicine · doi:10.1097/md.0000000000038227 · Cited by 8
Exercise therapy in the application of sleep disorders
Zhao, Y., Dai, Q., Li, Y., & Li, C. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1324112 · Cited by 8
Conceptual overlap of negative thought processes in insomnia: A focus on catastrophizing, worry, and rumination in a student sample
Jansson‐Fröjmark, M., Sunnhed, R., Carney, C. E., & Rosendahl, I. K. (2024) · Behavioral Sleep Medicine · doi:10.1080/15402002.2024.2374264 · Cited by 5
Uncovering the symptom relationship among sleep quality, anxiety, and depression in Chinese patients with breast cancer: multidimensional data validation using PSQI versus actigraphy
Tao, Y., Liu, Q., Ye, X., Feng, J., Liu, H., Wu, J., Zhang, J., Qian, L., Lu, J., & Liu, R. (2024) · Journal of Cancer Survivorship · doi:10.1007/s11764-024-01649-5 · Cited by 7
Sleep Disorders in Women: What Should a Gynecologist Know?
Aksan, A., & Dilbaz, B. (2024) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-2371-0763 · Cited by 5
Sleep Health and White Matter Integrity in the UK Biobank
Petri, R., Holub, F., Schiel, J. E., Feige, B., Rutter, M. K., Tamm, S., Riemann, D. W., Kyle, S. D., & Spiegelhalder, K. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70034 · Cited by 5
Self-citation
Is sleep compression therapy non-inferior to sleep restriction therapy? A single-blind randomized controlled non-inferiority trial comparing sleep compression therapy to sleep restriction therapy as treatment for insomnia
Jernelöv, S., Rosén, A., Forsell, E., Blom, K., Ivanova, E., Maurex, L., Jansson‐Fröjmark, M., Åkerstedt, T., & Kaldo, V. (2025) · SLEEP · doi:10.1093/sleep/zsaf093 · Cited by 5
IoT-Powered Mental Healthcare: Sleep State Analyzing and Monitoring Based on EEG Signals
Thuan, C., Khai, N. D., Nguyen, T. D., Thanh, N. T., Chau, P. H. M., Le, A. N., Nguyễn, V. Đ., & Chien, T. V. (2025) · IEEE Access · doi:10.1109/access.2025.3559932 · Cited by 7
A Digital Sleep Restriction System for Insomnia Therapy Based on Sleep Window Shift Negotiation
Uyumaz, B. E., Overeem, S., Feijs, L. M. G., Rama, M. D., & Hu, J. (2018) · International Conference on PErvasive Technologies Related to Assistive Environments (PETRA) · doi:10.1145/3197768.3201531 · Cited by 5
Cognitive Behavioural Therapy in Children and Adolescents
Suganya, M., Prabakar, S., & Rao, U. M. (2022) · Research Journal of Pharmacy and Technology · doi:10.52711/0974-360x.2022.00222 · Cited by 7
Unclear Insomnia Concept in Randomized Controlled Trials and Systematic Reviews: A Meta-Epidemiological Study
Banno, M., Tsujimoto, Y., Kohmura, K., Dohi, E., Taito, S., Someko, H., & Kataoka, Y. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191912261 · Cited by 4
Sedative–hypnotic effects of Boropinol-B on mice via activation of GABAA receptors
Mu, K., Zhang, J., Feng, X., Zhang, D., Li, K., Li, R., Yang, P., & Mao, S. (2022) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgac077 · Cited by 5
Individuals with clinically significant insomnia symptoms are characterised by a negative sleep-related expectancy bias: Results from a cognitive-experimental assessment
Courtauld, H. M., Notebaert, L., Milkins, D. B., Kyle, S. D., & Clarke, P. (2017) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.05.010 · Cited by 5
Self-reported sleeplessness in 12,655 persons living in the north of Norway: The Tromsø Study
Fetveit, A., Straand, J., Bjorvatn, B., & Kristoffersen, E. S. (2019) · Sleep Science · doi:10.5935/1984-0063.20190070 · Cited by 5
Zebrafish screen of high-confidence effector genes at insomnia GWAS loci implicates conserved regulators of sleep-wake behaviorsPreprint
Zimmerman, A. J., Doldur-Balli, F., Keenan, B. T., Shetty, Z. Y., Palermo, J., Chesi, A., Sonti, S., Pahl, M. C., Brown, E., Pippin, J. A., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.05.511011 · Cited by 5
Differences in Treatment Effects of Cognitive-behavioral Therapy for Insomnia Based on Sleep Reactivity: A Preliminary Study
Park, K., Kim, G., Lee, J., & Suh, S. (2023) · Behavioral Sleep Medicine · doi:10.1080/15402002.2022.2093880 · Cited by 7
Brain function assessment of acupuncture for chronic insomnia disorder with mild cognitive dysfunction based on fNIRS: protocol for a randomized controlled trial
Wang, T., Li, Z., Ma, T., Zhu, F., Bin, Y., Kim, S., Miao, R., & Wu, J. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1403785 · Cited by 4
Real-world evidence for the use of digital cognitive behavioural therapy for insomnia within primary care
Maurer, L., Aust, F., & Lorenz, N. (2025) · Somnologie - Schlafforschung und Schlafmedizin · doi:10.1007/s11818-025-00502-w · Cited by 4
The Interplay Between the Sleep Slow Oscillation and Cerebrospinal Fluid: New Vistas for Insomnia Research
Aquino, G., Palagini, L., Alfì, G., Feige, B., Spiegelhalder, K., Piarulli, A., & Gemignani, A. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70069 · Cited by 5
Self-citation
Novel insight into prediction model for sleep quality among college students: a LASSO-derived sleep evaluation
Yao, L., Chen, Q., Yang, K., Zheng, Z., Chen, Z., Wang, D., Xia, Y., Chen, D., & Chen, L. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1585732 · Cited by 5
Within-Person Bidirectional Relations Between Sleep Problems and Alcohol, Cannabis, and Co-Use Problems in a Representative U.S. Sample
Drazdowski, T. K., Kelly, L. M., Livingston, N. R., Sheidow, A. J., & McCart, M. R. (2025) · Substance Use & Misuse · doi:10.1080/10826084.2025.2523458 · Cited by 4
Habitual breakfast skipping and night eating associated with unfavorable changes in lipid profiles in Chinese adults: a longitudinal analysis
Gao, W., Zhe, H., Ba, D. M., Jigeer, G., Liu, Y., Chen, S., Li, Y., Sun, L., Wu, S., & Gao, X. (2025) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2025.08.007 · Cited by 4
Efficacy and safety of Shugan Jieyu capsules in combination with zolpidem for insomnia disorder with depressive symptoms: a double-blind randomized controlled trial
Xin, Q., Paudel, D., Zhang, J., Wei, H., Cheng, Y., Xu, Y., Fang, R., Jiang, J., Wang, Y., & Zhang, B. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-05142-z · Cited by 4
Neuroimaging findings in sleep disorders: A review article
Kavehee, A., Kashaninasab, F., Ghalebandi, M. F., & Khoozan, M. (2025) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2025.100137 · Cited by 4
Sleep disturbances and Alzheimer’s disease: a multiscale approach from exposome to neurobiology and precision medicine
Tahmasian, M., Elberse, J. D., Ahmadi, R., Wen, L., Rosenzweig, I., Genon, S., Eickhoff, S. B., & Mander, B. A. (2026) · GeroScience · doi:10.1007/s11357-026-02152-8 · Cited by 8
Cognitive behavioural therapy for insomnia (CBT-I) in schizophrenia and schizoaffective disorder: protocol for a randomised controlled trial
Tanskanen, T. E., Wegelius, A., Härkönen, T., Gummerus, E.-M., Stenberg, J., Selinheimo, S., Alakuijala, A., Tenhunen, M. L., Paajanen, T. I., Järnefelt, H., et al. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-076129 · Cited by 4
Role of metabolic characteristics in the co-occurrence of insomnia, Alzheimer’s disease, and Parkinson’s disease: a Mendelian randomization study
Liu, C., Wang, C., Jiang, J., Yang, B. K., Nan, L., Zhang, Y., Zhu, K., Wang, X., Feng, X., Lian, X., et al. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1436171 · Cited by 4
One Single Session to Sleep Them All? The Potential of Single‐Session Interventions for Insomnia
Carpi, M., Szkody, E. M., & Marques, D. R. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70134 · Cited by 6
Safety profile of ramelteon from the perspective of physicians and pharmacists: a 20-year real-world pharmacovigilance analysis based on the FAERS database
Wu, J., Zhou, Y., Qiu, L., Liu, L., Wang, F., Zhen, L., & Li, N. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07127-1 · Cited by 4
Esketamine Optimized the Efficacy of Dexmedetomidine in Treating Sleep Disorders with Comorbid Depression
Ding, Y., Wang, Z., Huang, J., Yi, Y., & Wu, Z. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s530265 · Cited by 4
The relationship between perceived organizational support and insomnia in psychiatric nurses in China: the mediating role of psychological capital
Zhang, J.-Y., Du, R.-N., Wang, Z., Chen, J.-X., Chen, N., Zhao, J., Wang, S.-F., & Cai, H. (2025) · BMC Nursing · doi:10.1186/s12912-025-03554-3 · Cited by 4
The use of the odds ratio product and self-reported data to detect comorbid insomnia and sleep apnea
Hanif, U., Guadagni, V., Lambing, K. A., Gimenez, U., Jennum, P., Sweetman, A., & Mysliwiec, V. (2025) · SLEEP · doi:10.1093/sleep/zsaf198 · Cited by 4
About the Other Side of Sleep Disorders: Improving Daytime Problems, Fatigue, Sleepiness, Cognitive Functioning and More
Jernelöv, S., & Blom, K. (2025) · Journal of Sleep Research · doi:10.1111/jsr.70164 · Cited by 4
White matter alterations in heart-kidney imbalance insomnia and Jiao-Tai-Wan treatment: A diffusion-tensor imaging study
Chen, J., Li, Y., Xia, N., Wen, C., Xia, T., Zhuang, Y., Jiang, M., Xiang, Y., Zhang, M., Zhan, C., et al. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-022-00653-6 · Cited by 5
Sub‐types of insomnia in adolescents: Insights from a quantitative/molecular twin study
Madrid‐Valero, J. J., Rijsdijk, F. V., Selzam, S., Zavos, H. M. S., Schneider, M. N., Ronald, A., & Gregory, A. M. (2023) · JCPP Advances · doi:10.1002/jcv2.12167 · Cited by 3
Identifying emerging trends and hot topics through intelligent data mining: the case of clinical psychology and psychotherapy
Соколова, А., Лобанова, П., & Kuzminov, I. (2023) · foresight · doi:10.1108/fs-02-2023-0026 · Cited by 5
Insomnia medications: History, characteristics, and guidelines for optimal use in clinical practice
Krystal, A. D. (2023) · Journal of Sleep Research · doi:10.1111/jsr.14084 · Cited by 5
Self-citation
Who benefits from indirect prevention and treatment of depression using an online intervention for insomnia? Results from an individual-participant data meta-analysis
Thielecke, J., Kuper, P. R., Lehr, D., Schuurmans, L., Harrer, M., Ebert, D. D., Cuijpers, P. J., Behrendt, D., Brückner, H., Horvath, H., et al. (2024) · Psychological Medicine · doi:10.1017/s0033291724000527 · Cited by 4
Sleep fragmentation despite intact rest-activity patterns in premanifest Huntington's disease: An actigraphy study
Fitzgerald, E. S., Manousakis, J. E., Glikmann‐Johnston, Y., Rankin, M., Anderson, C., Stout, J. C., & Jackson, M. L. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.08.026 · Cited by 4
Daily Associations Between Sleep Parameters and Depressive Symptoms in Individuals with Insomnia: Investigating Emotional Reactivity and Regulation as Mediators
Tsui, H. T. C., & Chan, W. S. (2024) · Behavioral Sleep Medicine · doi:10.1080/15402002.2024.2399620 · Cited by 4
Insomnia and stress: the mediating roles of frontoparietal network
He, M., Li, Y., Chen, M., Li, H., Liang, C., Chen, Y., Long, C., Yang, Y., Ye, J., Mao, Y., et al. (2024) · Brain Imaging and Behavior · doi:10.1007/s11682-024-00922-6 · Cited by 5
Effectiveness of digital cognitive behavioral therapy for insomnia on professional activity: A systematic review and meta-analysis of randomized controlled trials
Zettor, D., Endomba, F. T., Pierandrei, A., Pinoit, J., Chauvet‐Gélinier, J., Forestier, N., & Hussami, A. (2024) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2024.102024 · Cited by 4
A cross-tissue transcriptome-wide association study identifies new susceptibility genes for insomnia
Li, L., Wu, D., Zhang, C., Lai, X., Zhang, R., Hu, S., & Ye, Y. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00490.2024 · Cited by 4
A systematic review and narrative synthesis of the complex interplay between psychological flexibility and sleep health
Ryan, E. C., O'Neill, D., & Smyth, S. (2025) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2025.100871 · Cited by 6
Preclinical models of insomnia: advances, limitations, and future directions for drug discovery
Arias-Carrión, Ó. (2025) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2025.2528135 · Cited by 4
Preface for the 3rd Clinical Update Sleep, 23rd February 2018, Royal College of Physicians, London, UK: year in review
Ratneswaran, C., Sagoo, M. K., & Steier, J. S. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.10.162 · Cited by 6
Personality Processes and Sleep: An Overview and a Leitmotif for a Research Agenda
Duggan, K. A., & Križan, Z. (2019) · Springer eBooks · doi:10.1007/978-3-030-30628-1_12 · Cited by 4
Identifying insomnia-related chemicals through integrative analysis of genome-wide association studies and chemical–genes interaction information
Kafle, O. P., Cheng, S., Ma, M., Li, P., Cheng, B., Zhang, P., Wen, Y. F., Liang, C., Qi, X., & Zhang, F. (2020) · SLEEP · doi:10.1093/sleep/zsaa042 · Cited by 4
Gegenseitige Beeinflussung von Insomnie im Alter und assoziierten Erkrankungen
Schiel, J. E., & Spiegelhalder, K. (2020) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-020-01694-6 · Cited by 4
Self-citation
Analysis of GABRB3 gene mRNA expression and motor coordination after administration of valerian extracts (Valeriana officinalis) in BALB/c mice
Mulyawan, E., Ahmad, M. R., Islam, A. A., Massi, M. N., Hatta, M., & Arif, S. K. (2020) · F1000Research · doi:10.12688/f1000research.24386.1 · Cited by 4
Decreased Transition Rate From Situational Insomnia to Chronic Insomnia by One-Week Internet Cognitive Behavioral Treatments for Insomnia During the COVID-19 Pandemic
Feng, F., Zhang, C., Liang, H., Guojian, X., Luo, X., Liu, S., Xu, Y. J., Yang, L., Zhang, L., Lin, L.-H., et al. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.837399 · Cited by 4
Lack of Structural Brain Alterations associated with Insomnia: Findings from the ENIGMA-Sleep working groupPreprint
Weihs, A., Frenzel, S., Bi, H., Schiel, J. E., Afshani, M., Bülow, R., Ewert, R., Fietze, I., Hoffstaedter, F., Jahanshad, N., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2203610/v1 · Cited by 4
Self-citation
Prevalence of Sleep Quality among Academic Staff of a Private University in Malaysia
Thiagarajah, K., Sit, N. W., & Chee, H. P. (2023) · Malaysian Journal of Medicine and Health Sciences · doi:10.47836/mjmhs.19.6.5
Anxiolytic-like effects of the dual orexin receptor antagonist daridorexant in rats
Steiner, M. A., Locher, R., Lecourt, H., & Jenck, F. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104056 · Cited by 3
Negative emotional reactivity and maladaptive emotional regulation strategies mediate the prospective relationship between depressive symptoms and insomnia symptoms in individuals with insomnia
Tsui, H. T. C., & Chan, W. S. (2024) · Journal of Affective Disorders Reports · doi:10.1016/j.jadr.2024.100766 · Cited by 3
Assessment of Intravoxel Incoherent Motion Diffusion‐Weighted Imaging in Insomnia
Tang, W., Debora, A., Miao, S., Lin, B., Huang, Q., Yuan, Z., Yang, Y., & Xia, N. (2025) · Brain and Behavior · doi:10.1002/brb3.70785 · Cited by 3
Positive Childhood Experiences and Insomnia: Psychological Vulnerability and Subjective Vitality as Serial Mediators
Kara, B. C., Dalkılınç, G., Guven, S. N., Kesimalioglu, H., & Satıcı, S. A. (2025) · Psychiatric Quarterly · doi:10.1007/s11126-025-10200-3 · Cited by 3
EEG-Based Multi-Class Sleep Disorder Classification Using Deep Learning, Machine Learning and Neural Tangent Kernel
Madhav, M., Rohit, V., Mohan, N., & Kumar, S. S. (2025) · International Conference on Intelligent Technologies (CONIT) · doi:10.1109/conit65521.2025.11166752 · Cited by 3
Global research dynamics in the Tai Chi and insomnia: a bibliometric study from 2006 to 2025
Liao, M. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1669378 · Cited by 4
Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System
Afroz, M., Hasan, R., Khatun, M. M., Tito, M. H., Shadin, M., Chakma, R., Asiri, M., Altemani, F. H., Altemani, A. H., Bhuia, M. S., et al. (2025) · ChemistryOpen · doi:10.1002/open.202500397 · Cited by 3
The effectiveness of Cognitive behavioral therapy for insomnia on sleep EEG hyperarousal: a multicentric polysomnographic study
Sforza, M., Morin, C., Dang‐Vu, T. T., Pomares, F. B., Perrault, A. A., Gouin, J.-P., Bušková, J., Janků, K., Vgontzas, A. N., Fernández‐Mendoza, J., et al. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-03882-1 · Cited by 6
Self-citation
Digital Cognitive Behavioural Therapy for Insomnia Delivered Within a Crenotherapy Setting: Results from a Multicentre Proof-of-Concept Randomised Controlled Trial
Julie, L., Mengarduque, M., Coelho, J., Geoffroy, P. A., Denechere, E., Aouizerate, B., Jaafari, N., Philip, P., Taillard, J., Dubois, O., et al. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15062176 · Cited by 3
Neural-molecular signatures of insomnia: Insights from signed differential mapping and gene expression analysis
Wang, R., He, Y., Myachykov, A., Leong, C., Gao, W., Zhang, C., He, Y., & Yuan, Z. (2026) · NeuroImage · doi:10.1016/j.neuroimage.2026.121926 · Cited by 3
Schlafstörungen
Pollmächer, T. (2017) · Springer eBooks · doi:10.1007/978-3-662-49295-6_76 · Cited by 3
Unexpected association between ambient ozone and adult insomnia outpatient visits: A large-scale hospital-based study
Li, D., Yang, L., Wang, N., Hu, Y.-G., Zhou, Y., Du, N., Liu, X., Liu, X., Yao, C., Wu, N., et al. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.138484 · Cited by 3
How can we find functional neuroimaging evidence for the hyperarousal theory of insomnia?
Kang, S. (2023) · SLEEP · doi:10.1093/sleep/zsad215 · Cited by 3
Mapping the Neural Basis of Wake Onset Regularity and Its Effects on Sleep Quality and Positive Affect
Negelspach, D., Kennedy, K. E. R., Huskey, A., Cha, J., Alkozei, A., & Killgore, W. D. S. (2025) · Clocks & Sleep · doi:10.3390/clockssleep7010015 · Cited by 3

Authors: Morin, C. M., Drake, C. L., Harvey, A. G., Krystal, A. D., Manber, R., Riemann, D., & Spiegelhalder, K.
Affiliations: Université Laval (CA)
Henry Ford Hospital (US)
University of California, Berkeley (US)
Duke University (US)
Stanford Medicine (US)
University of Freiburg (DE)
Corresponding author: Morin, Charles M.
ORCID: Morin, Charles M.
Drake, Christopher L.
Harvey, Allison G.
Krystal, Andrew D.
Manber, Rachel
Riemann, Dieter
Spiegelhalder, Kai
Venue: Nature Reviews Disease Primers
Publisher: Springer Science and Business Media LLC
Published: 2015-09-03
Volume: 1
Issue: 1
Pages: 15026-15026
ISSN: 2056-676X (ISSN-L)
DOI: 10.1038/nrdp.2015.26
OpenAlex: W4211107190
Cited by: 746
References: 191
Citations by year: 2026: 72 · 2025: 120 · 2024: 111 · 2023: 119 · 2022: 97 · 2021: 75 · 2020: 65 · 2019: 34 · 2018: 20 · 2017: 23 · 2016: 6 · 2015: 4
FWCI: 2.28
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature Reviews Disease Primers (publishedVersion)
PubMed (publishedVersion)
Corpus Université Laval (Université Laval) (submittedVersion)
Funders: Canadian Institutes of Health Research (MOP42504)
National Institute of Mental Health (R01MH091053, R01MH105513)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: insomnia, sleep onset insomnia, sleep maintenance insomnia, insomnia classification, insomnia pathophysiology, insomnia treatment, pharmacotherapy, psychotherapy, quality of life, comorbid depression, chronic insomnia
MeSH terms: Activities of Daily Living, Depression, Humans, Sleep Initiation and Maintenance Disorders, Pain, Quality of Life, Stress, Psychological

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Insomnia disorder

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks