Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

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Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

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Biallelic Inactivation of BRCA2 in Fanconi Anemia

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PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

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BRCA2 Is Required for Homology-Directed Repair of Chromosomal Breaks

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Control of BRCA2 Cellular and Clinical Functions by a Nuclear Partner, PALB2

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Interaction of Human DNA Polymerase η with Monoubiquitinated PCNA

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BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure

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Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair

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Insights into DNA recombination from the structure of a RAD51–BRCA2 complex

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RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites

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Abraxas and RAP80 Form a BRCA1 Protein Complex Required for the DNA Damage Response

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Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer

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Cloning of cDNAs for Fanconi's anaemia by functional complementation

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The Deubiquitinating Enzyme USP1 Regulates the Fanconi Anemia Pathway

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Regulation of monoubiquitinated PCNA by DUB autocleavage

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A novel ubiquitin ligase is deficient in Fanconi anemia

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The emerging genetic and molecular basis of Fanconi anaemia

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Repair of DNA interstrand cross-links

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Ubiquitin-Binding Protein RAP80 Mediates BRCA1-Dependent DNA Damage Response

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Disruption of the Fanconi anemia–BRCA pathway in cisplatin-sensitive ovarian tumors

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The Fanconi Anemia/BRCA pathway: new faces in the crowdPreprint

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Fanconi anemia is associated with a defect in the BRCA2 partner PALB2

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A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

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S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51

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Convergence of the Fanconi Anemia and Ataxia Telangiectasia Signaling Pathways

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The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J

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ATR couples FANCD2 monoubiquitination to the DNA-damage responsePreprint

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BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo.

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Positional Cloning of a Novel Fanconi Anemia Gene, FANCD2

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Expression cloning of a cDNA for the major Fanconi anaemia gene, FAA

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BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ

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Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

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The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia

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A Multiprotein Nuclear Complex Connects Fanconi Anemia and Bloom Syndrome

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Functional Interaction of Monoubiquitinated FANCD2 and BRCA2/FANCD1 in Chromatin

Wang, X., Andreassen, P. R., & D’Andrea, A. D. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.13.5850-5862.2004 · Cited by 337

Identification of FAAP24, a Fanconi Anemia Core Complex Protein that Interacts with FANCM

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The Fanconi anaemia group G gene FANCG is identical with XRCC9

de Winter, J. P., Waisfisz, Q., Rooimans, M. A., van Berkel, C. G. M., Bosnoyan-Collins, L., Alon, N., Carreau, M., Bender, O., Demuth, I., Schindler, D., et al. (1998) · Nature Genetics · doi:10.1038/3093 · Cited by 333

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1

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X-linked inheritance of Fanconi anemia complementation group B

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The Fanconi Anaemia Gene FANCC Promotes Homologous Recombination and Error-Prone DNA Repair

Niedźwiedź, W., Mosedale, G., Johnson, M. A., Ong, C. Y., Pace, P., & Patel, K. J. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.08.009 · Cited by 310

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes

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Fanconi Anemia (Cross)linked to DNA Repair

Niedernhofer, L. J., Lalai, A. S., & Hoeijmakers, J. H. J. (2005) · Cell · doi:10.1016/j.cell.2005.12.009 · Cited by 298

UBE2T Is the E2 in the Fanconi Anemia Pathway and Undergoes Negative Autoregulation

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The structure‐specific endonuclease Mus81–Eme1 promotes conversion of interstrand DNA crosslinks into double‐strands breaks

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Evidence for at least four Fanconi anaemia genes including FACC on chromosome 9

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FANCI is a second monoubiquitinated member of the Fanconi anemia pathway

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Repair of an Interstrand DNA Cross-link Initiated by ERCC1-XPF Repair/Recombination Nuclease

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Positional cloning of the Fanconi anaemia group A gene

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Interaction of FANCD2 and NBS1 in the DNA damage response

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Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout micePreprint

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The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM

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Fanconi anemia gene mutations in young-onset pancreatic cancer.

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The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations

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The DNA crosslink‐induced S‐phase checkpoint depends on ATR–CHK1 and ATR–NBS1–FANCD2 pathways

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Fanconi Anemia Proteins FANCA, FANCC, and FANCG/XRCC9 Interact in a Functional Nuclear Complex

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Isolation of a cDNA Representing the Fanconi Anemia Complementation Group E Gene

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POLQ (Pol ), a DNA polymerase and DNA-dependent ATPase in human cells

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The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair

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Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway

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Tracing the network connecting brca and fanconi anaemia proteins

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The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

de Winter, J. P. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.18.2665 · Cited by 194

The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

Mosedale, G., Niedźwiedź, W., Alpi, A. F., Perrina, F., Pereira‐Leal, J. B., Johnson, M. A., Langevin, F., Pace, P., & Patel, K. J. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb981 · Cited by 191

Multiple Repair Pathways Mediate Tolerance to Chemotherapeutic Cross-linking Agents in Vertebrate Cells

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The Fanconi anaemia proteins, FAA and FAC interact to form a nuclear complex

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The FANCJ/MutLα interaction is required for correction of the cross‐link response in FA‐J cells

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BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

Yin, J., Sobeck, A., Xu, C., Meetei, A. R., Hoatlin, M. E., Li, L., & Wang, W. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600622 · Cited by 180

Nbs1 is required for ATR‐dependent phosphorylation events

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FANCE: the link between Fanconi anaemia complex assembly and activity

Pace, P., Johnson, M., Tan, W. M., Mosedale, G., Sng, C. C. A., Hoatlin, M., de Winter, J. P., Joenje, H., Gergely, F. V., & Patel, K. J. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf355 · Cited by 172

FAAP100 is essential for activation of the Fanconi anemia‐associated DNA damage response pathway

Ling, C., Ishiai, M., Ali, A. M., Medhurst, A. L., Neveling, K., Kalb, R., Yan, Z., Xue, Y., Oostra, A. B., Auerbach, A. D., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601666 · Cited by 170

Direct interactions of the five known Fanconi anaemia proteins suggest a common functional pathway

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Fanconi Anemia FANCG Protein in Mitigating Radiation- and Enzyme-Induced DNA Double-Strand Breaks by Homologous Recombination in Vertebrate Cells

Yamamoto, K., Ishiai, M., Matsushita, N., Arakawa, H., Lamerdin, J. E., Buerstedde, J.-M., Tanimoto, M., Harada, M., Thompson, L. H., & Takata, M. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5421-5430.2003 · Cited by 151

Chk1-Mediated Phosphorylation of FANCE Is Required for the Fanconi Anemia/BRCA Pathway

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The Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm

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A FancD2-Monoubiquitin Fusion Reveals Hidden Functions of Fanconi Anemia Core Complex in DNA Repair

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Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance

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Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein, FANCD2, Sustain a Significant Group of FA-D2 Patients with Severe Phenotype

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Identification of the Fanconi Anemia Complementation Group I Gene, FANCI

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The Fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation

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Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability

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Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM

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