The DOI matches its Crossref record; 126 of the 126 references it cites were found in a registry or an index.
The evolution of cell types in animals: emerging principles from molecular studies
Abstract
Cell types are fundamental units of multicellular life but their evolution is obscure. How did the first cell types emerge and become distinct in animal evolution? What were the sets of cell types that existed at important evolutionary nodes that represent eumetazoan or bilaterian ancestors? How did these ancient cell types diversify further during the evolution of organ systems in the descending evolutionary lines? The recent advent of cell type molecular fingerprinting has yielded initial insights into the evolutionary interrelationships of cell types between remote animal phyla and has allowed us to define some first principles of cell type diversification in animal evolution.
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“Studies over the past century have revealed that cells within an organism can be grouped into types – cells within a type exhibit similar structure and function that are distinct from cells in other types (Arendt, 2008).”
From What is a cell type and how to define it? (2022) · cites this paper as Arendt, 2008
Citations
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Huerta‐Cepas, J., Szklarczyk, D., Heller, D., Hernández-Plaza, A., Forslund, S. K., Cook, H., Mende, D. R., Letunić, I., Rattei, T., Jensen, L. J., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky1085 · Cited by 4,934
A census of human transcription factors: function, expression and evolution
Vaquerizas, J. M., Kummerfeld, S. K., Teichmann, S. A., & Luscombe, N. M. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2538 · Cited by 1,573
Single-cell sequencing-based technologies will revolutionize whole-organism science
Shapiro, E., Biezuner, T., & Linnarsson, S. (2013) · Nature Reviews Genetics · doi:10.1038/nrg3542 · Cited by 1,177
The origin and evolution of cell types
Arendt, D., Musser, J. M., Baker, C. V. H., Bergman, A., Cepko, C., Erwin, D. H., Pavlicev, M., Schlosser, G., Widder, S., Laubichler, M. D., et al. (2016) · Nature Reviews Genetics · doi:10.1038/nrg.2016.127 · Cited by 764
Self-citationTissue biology perspective on macrophages
Okabe, Y., & Medzhitov, R. M. (2015) · Nature Immunology · doi:10.1038/ni.3320 · Cited by 651
Metadata
- Authors
- Arendt, D.
- Affiliations
- European Molecular Biology Laboratory (DE)
- Corresponding author
- Arendt, Detlev
- ORCID
- Arendt, Detlev
- Venue
- Nature Reviews Genetics
- Published
- 2008-11
- Volume
- 9
- Issue
- 11
- Pages
- 868-882
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2072977772
- Cited by
- 525
- References
- 126
- Citations by year
- 2026: 25 · 2025: 33 · 2024: 44 · 2023: 50 · 2022: 30 · 2021: 33 · 2020: 37 · 2019: 27 · 2018: 26 · 2017: 28 · 2016: 24 · 2015: 45 · 2014: 31 · 2013: 19 · 2012: 17
- FWCI
- 1.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature Reviews Genetics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Marine Invertebrate Physiology and Ecology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Keywords
- cell type evolution, animal evolution, multicellularity
- MeSH terms
- Animals, Cell Differentiation, Endocrine System, Biological Evolution, Immune System, Nervous System, Phylogeny, DNA Fingerprinting, Cell Lineage
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