The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Open accessAbstract
Histone deacetylases (HDACs) are part of a vast family of enzymes that have crucial roles in numerous biological processes, largely through their repressive influence on transcription. The expression of many HDAC isoforms in eukaryotic cells raises questions about their possible specificity or redundancy, and whether they control global or specific programmes of gene expression. Recent analyses of HDAC knockout mice have revealed highly specific functions of individual HDACs in development and disease. Mutant mice lacking individual HDACs are a powerful tool for defining the functions of HDACs in vivo and the molecular targets of HDAC inhibitors in disease.
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Cites
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Metadata
- Authors
- Haberland, M., Montgomery, R. L., & Olson, E. N.
- Venue
- Nature Reviews Genetics
- Published
- 2009-01
- Volume
- 10
- Issue
- 1
- Pages
- 32-42
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2108017291
- Cited by
- 2,526
- References
- 17
- FWCI
- 5.31
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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