Mapping complex disease traits with global gene expression

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature · doi:10.1038/nature05911 · Cited by 9,442

Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities

Faith, M. S., Carnell, S., & Kral, T. V. E. (2013) · Human Heredity · doi:10.1159/000353879 · Cited by 7,633

A General Framework for Weighted Gene Co-Expression Network Analysis

Zhang, B., & Horvath, S. (2005) · Statistical Applications in Genetics and Molecular Biology · doi:10.2202/1544-6115.1128 · Cited by 5,684

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature · doi:10.1038/35079107 · Cited by 5,591

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Lamb, J., Crawford, E. D., Peck, D., Modell, J. W., Blat, I. C., Wrobel, M. J., Lerner, J., Brunet, J.-P., Subramanian, A., Ross, K. N., et al. (2006) · Science · doi:10.1126/science.1132939 · Cited by 5,257

The human disease network

Goh, K.-I., Cusick, M. E., Valle, D., Childs, B., Vidal, M., & Barabási, A.-L. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701361104 · Cited by 3,242

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Palmer, C. N. A., Irvine, A. D., Terron-Kwiatkowski, A., Zhao, Y., Liao, H., Lee, S. P., Goudie, D. R., Sandilands, A., Campbell, L. E., Smith, F. J. D., et al. (2006) · Nature Genetics · doi:10.1038/ng1767 · Cited by 2,978

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

the NIDDK IBD Genetics Consortium, Barrett, J. C., the Belgian-French IBD Consortium, the Wellcome Trust Case Control Consortium, Hansoul, S., Nicolae, D. L., Cho, J. H., Duerr, R. H., Rioux, J. D., Brant, S. R., et al. (2008) · Nature Genetics · doi:10.1038/ng.175 · Cited by 2,593

Heritability in the genomics era — concepts and misconceptions

Visscher, P. M., Hill, W. G., & Wray, N. R. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2322 · Cited by 1,921

An Oncogene-Induced DNA Damage Model for Cancer Development

Halazonetis, T. D., Gorgoulis, V. G., & Bartek, J. (2008) · Science · doi:10.1126/science.1140735 · Cited by 1,851

Genetic Dissection of Nutrition-Induced Plasticity in Insulin/Insulin-Like Growth Factor Signaling and Median Life Span in aDrosophilaMultiparent Population

Stanley, P. D., Ng’oma, E., O’Day, S., & King, E. G. (2017) · Genetics · doi:10.1534/genetics.116.197780 · Cited by 30

Genetics of canine myxomatous mitral valve disease

O’Brien, M. J., Beijerink, N., & Wade, C. M. (2021) · Animal Genetics · doi:10.1111/age.13082 · Cited by 29

The molecular basis, genetic control and pleiotropic effects of local gene co-expression

Ribeiro, D. M., Rubinacci, S., Ramisch, A., Hofmeister, R. J., Dermitzakis, E. T., & Delaneau, O. (2021) · Nature Communications · doi:10.1038/s41467-021-25129-x · Cited by 31

Understanding Gene Expression and Transcriptome Profiling of COVID-19: An Initiative Towards the Mapping of Protective Immunity Genes Against SARS-CoV-2 Infection

Chakraborty, C., Sharma, A. R., Bhattacharya, M., Zayed, H., & Lee, S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.724936 · Cited by 29

Modification of starch content and its management strategies in plants in response to drought and salinity: current status and future prospects

Hasan, M. M., Alabdallah, N. M., Salih, A. M., Al-Shammari, A. S., AlZahrani, S. S., Lawati, A. H. A., Jahan, M. S., Rahman, M. A., & Fang, X. (2022) · Journal of soil science and plant nutrition · doi:10.1007/s42729-022-01057-7 · Cited by 29

Statistical Approaches for Identifying eQTLs (Expression Quantitative Trait Loci) in Plant and Human Genomes

Mahama, T. (2023) · International Journal of Science and Research Archive · doi:10.30574/ijsra.2023.10.2.0998 · Cited by 28

Computational Analysis of Whole-Genome Differential Allelic Expression Data in Human

Wagner, J. R., Ge, B., Pokholok, D., Gunderson, K. L., Pastinen, T., & Blanchette, M. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000849 · Cited by 28

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

Andiappan, A. K., Melchiotti, R., Poh, T. Y., Nah, M., Puan, K. J., Viganò, E., Haase, D., Yusof, N., Luis, B. S., Lum, J., et al. (2015) · Nature Communications · doi:10.1038/ncomms8971 · Cited by 28

Extended Bayesian information criterion in the Cox model with a high-dimensional feature space

Luo, S., Xu, J., & Chen, Z. (2014) · Annals of the Institute of Statistical Mathematics · doi:10.1007/s10463-014-0448-y · Cited by 28

Identification of Critical Elements for Regulation of Inorganic Pyrophosphatase (PPA1) in MCF7 Breast Cancer Cells

Mishra, D. R., Chaudhary, S., Krishna, B. M., & Mishra, S. K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124864 · Cited by 28

Association Weight Matrix: A Network-Based Approach Towards Functional Genome-Wide Association Studies

Reverter, A., & Fortes, M. R. S. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-447-0_20 · Cited by 28

Integrative omics of the genetic basis for wheat WUE and drought resilience reveal the function of TaMYB7-A1

Zhou, Y., Wang, D., Wang, H. M., Qiao, Y., Zhao, P., Cao, Y., Liu, X., Yang, Y., Lin, X., Xu, S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63642-5 · Cited by 30

The BDNF Val66Met variant affects gene expression through miR-146b

Hsu, P.-K., Xu, B., Mukai, J., Karayiorgou, M., & Gogos, J. A. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.03.004 · Cited by 30

Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis

Guan, J., Yang, E., Yang, J., Zeng, Y., Ji, G., & Cai, J. J. (2016) · Human Genetics · doi:10.1007/s00439-016-1673-7 · Cited by 28

Influence of sex and genetic variability on expression of X-linked genes in human monocytes

Castagné, R., Zeller, T., Rotival, M., Szymczak, S., Trương, V., Schillert, A., Trégouët, D., Münzel, T. F., Ziegler, A., Cambien, F., et al. (2011) · Genomics · doi:10.1016/j.ygeno.2011.06.009 · Cited by 27

Genetic variability of transcript abundance in pig peri-mortem skeletal muscle: eQTL localized genes involved in stress response, cell death, muscle disorders and metabolism

Liaubet, L., Lobjois, V., Faraut, T., Tircazes, A., Benne, F., Iannuccelli, N., Pires, J., Glénisson, J., Robic, A., Roy, P. L., et al. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-548 · Cited by 31

Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor

Lü, Y., Liu, P., James, M. A., Vikis, H. G., Liu, H., Wu, W., Franklin, A. D., & You, M. (2009) · Oncogene · doi:10.1038/onc.2009.396 · Cited by 27

Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma

Hulur, I., Skol, A. D., Gamazon, E. R., Cox, N. J., & Onel, K. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185730 · Cited by 26

Roles of mitochondrial genetics in cancer metastasis

Welch, D. R., Foster, C., & Rigoutsos, I. (2022) · Trends in cancer · doi:10.1016/j.trecan.2022.07.004 · Cited by 26

A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies

Shi, X., Chai, X., Yang, Y., Cheng, Q., Jiao, Y., Chen, H., Huang, J., Yang, C., & Liu, J. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa767 · Cited by 26

Functional genomics of human brain development and implications for autism spectrum disorders

Ziats, M. N., Grosvenor, L. P., & Rennert, O. M. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.153 · Cited by 27

I-GSEA4GWAS v2: a web server for functional analysis of SNPs in trait-associated pathways identified from genome-wide association study

Zhang, K., Chang, S., Guo, L., & Wang, J. (2014) · Protein & Cell · doi:10.1007/s13238-014-0114-4 · Cited by 26

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

Li, H., Achour, I., Bastarache, L. A., Berghout, J., Gardeux, V., Li, J., Lee, Y., Pesce, L. L., Yang, X. H., Ramos, K. S., et al. (2016) · npj Genomic Medicine · doi:10.1038/npjgenmed.2016.6 · Cited by 27

OpenMendel: a cooperative programming project for statistical genetics

Zhou, H., Sinsheimer, J. S., Bates, D. M., Chu, B. B., German, C., Ji, S. S., Keys, K. L., Kim, J., Ko, S., Mosher, G., et al. (2019) · Human Genetics · doi:10.1007/s00439-019-02001-z · Cited by 28

An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6

Fairfax, B. P., Vannberg, F. O., Radhakrishnan, J., Hakonarson, H. H., Keating, B. J., Hill, A. V. S., & Knight, J. C. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp530 · Cited by 26

Genetics of Atopic Dermatitis

Weidinger, S., & Irvine, A. D. (2011) · Wiley eBooks · doi:10.1002/9781444345384.ch23 · Cited by 26

Evidence for a common evolutionary rate in metazoan transcriptional networks

Carvunis, A., Wang, T., Skola, D., Yu, A., Chen, J., Kreisberg, J. F., & Ideker, T. (2015) · eLife · doi:10.7554/elife.11615 · Cited by 26

The Length of the Expressed 3′ UTR Is an Intermediate Molecular Phenotype Linking Genetic Variants to Complex Diseases

Mariella, E., Marotta, F., Grassi, E., Gilotto, S., & Provero, P. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00714 · Cited by 25

Genomics meets proteomics: identifying the culprits in disease

Stunnenberg, H. G., & Hubner, N. C. (2013) · Human Genetics · doi:10.1007/s00439-013-1376-2 · Cited by 26

Novel Insights into the Regulatory Architecture of CD4+ T Cells in Rheumatoid Arthritis

Aterido, A., Palacio, C., Marsal, S., Avila-Pedretti, G., & Julià, A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0100690 · Cited by 26

Genome-wide association study of bronchial asthma in the Volga-Urals region of Russia

Karunas, A. S., Yunusbayev, B., Fedorova, Y. Y., Gimalova, G. F., Рамазанова, Н. Н., Гурьева, Л. Л., Мухтарова, Л. А., Загидуллин, Ш. З., Etkina, E. I., & Хуснутдинова, Э. К. (2011) · Molecular Biology · doi:10.1134/s0026893311060057 · Cited by 26

Post genome-wide association studies functional characterization of prostate cancer risk loci

Jiang, J., Cui, W., Vongsangnak, W., Hu, G., & Shen, B. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-s8-s9 · Cited by 25

Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

Gupta, S., Radhakrishnan, A., Raharja-Liu, P., Lin, G., Steinmetz, L. M., Gagneur, J., & Sinha, H. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005195 · Cited by 27

Genetics of primary hypertension: The clinical impact of adducin polymorphisms

Citterio, L., Lanzani, C. L., Manunta, P., & Bianchi, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.03.014 · Cited by 25

Risks and Function of Breast Cancer Susceptibility Alleles

Dalivandan, S. T., Plummer, J., & Gayther, S. A. (2021) · Cancers · doi:10.3390/cancers13163953 · Cited by 26

Parameters in Dynamic Models of Complex Traits are Containers of Missing Heritability

Wang, Y., Gjuvsland, A. B., Vik, J. O., Smith, N. P., Hunter, P. J., & Omholt, S. W. (2012) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1002459 · Cited by 25

Genetic determinants of HSP70 gene expression following heat shock

Maugeri, N., Radhakrishnan, J., & Knight, J. C. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq418 · Cited by 25

Exonuclease 1 (EXO1) gene variation and melanoma risk

Song, F., Qureshi, A. A., Zhan, J., Amos, C. I., Lee, J. E., Wei, Q., & Han, J. (2012) · DNA repair · doi:10.1016/j.dnarep.2011.12.005 · Cited by 24

Systems genetics in “-omics” era: current and future development

Li, H. (2012) · Theory in Biosciences · doi:10.1007/s12064-012-0168-x · Cited by 24

eQTL Epistasis – Challenges and Computational Approaches

Huang, Y., Wuchty, S., & Przytycka, T. M. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00051 · Cited by 24

Advances in the Genetics of Anti-Glomerular Basement Membrane Disease

Zhou, S., Lv, J., Zhao, M., & Zhang, H. (2010) · American Journal of Nephrology · doi:10.1159/000321324 · Cited by 24

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors

Gao, C., Tignor, N. L., Salit, J., Strulovici‐Barel, Y., Hackett, N. R., Crystal, R. G., & Mezey, J. G. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt690 · Cited by 24

Correlation of the Osteoarthritis Susceptibility Variants That Map to Chromosome 20q13 With an Expression Quantitative Trait Locus Operating on NCOA3 and With Functional Variation at the Polymorphism rs116855380

Gee, F., Rushton, M. D., Loughlin, J. A., & Reynard, L. N. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39278 · Cited by 24

Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study

Nymberg, C., Jia, T., Ruggeri, B., & Schumann, G. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12088 · Cited by 25

Allelic imbalance of multiple sclerosis susceptibility genes IKZF3 and IQGAP1 in human peripheral blood

Keshari, P., Harbo, H. F., Myhr, K., Aarseth, J. H., Bos, S. D., & Berge, T. (2016) · BMC Genetics · doi:10.1186/s12863-016-0367-4 · Cited by 25

Interactome-transcriptome analysis discovers signatures complementary to GWAS Loci of Type 2 Diabetes

Li, J., Lee, H. M., Wang, Y., Tong, A. H.-Y., Yip, K. Y.-L., Tsui, S. K., Lok, S., Ozaki, R., Luk, A. O. Y., Kong, A. P. S., et al. (2016) · Scientific Reports · doi:10.1038/srep35228 · Cited by 24

Therapeutic Approaches and Role of ncRNAs in Cardiovascular Disorders and Insulin Resistance

Liyanage, K. I. P., & Ganegoda, G. U. (2017) · BioMed Research International · doi:10.1155/2017/4078346 · Cited by 23

The Future of Neuroepigenetics in the Human Brain

Mitchell, A., Roussos, P., Peter, C. J., Tsankova, N. M., & Akbarian, S. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-800977-2.00008-5 · Cited by 24

Genome-wide search for exonic variants affecting translational efficiency

Li, Q., Makri, A., Lu, Y. Z., Marchand, L., Grabs, R., Rousseau, M., Ounissi‐Benkalha, H., Pelletier, J., Robert, F., Harmsen, E., et al. (2013) · Nature Communications · doi:10.1038/ncomms3260 · Cited by 23

Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation

Martin, M. V., Rollins, B. L., Sequeira, A., Mesén, A., Byerley, W., Stein, R., Moon, E. A., Akil, H., Jones, E. G., Watson, S. J., et al. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-62 · Cited by 23

Genome-wide association studies in bladder cancer: first results and potential relevance

Kiemeney, L. A. L. M., Grotenhuis, A. J., Vermeulen, S. H. H. M., & Wu, X. (2009) · Current Opinion in Urology · doi:10.1097/mou.0b013e32832eb336 · Cited by 23

Functional annotation of HOT regions in the human genome: implications for human disease and cancer

Li, H., Chen, H., Liu, F., Ren, C., Wang, S., Bo, X., & Shu, W. (2015) · Scientific Reports · doi:10.1038/srep11633 · Cited by 23

Lack of association of vitamin D receptor gene 3′‐haplotypes with psoriasis in Croatian patients

Ručević, I., Štefanić, M., Tokić, S., Vukšić, M., Glavaš‐Obrovac, L., & Barišić-Druško, V. (2011) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2011.01296.x · Cited by 23

Celiac disease: moving from genetic associations to causal variants

Hrdličková, B., Westra, H.-J., Franke, L., & Wijmenga, C. (2011) · Clinical Genetics · doi:10.1111/j.1399-0004.2011.01707.x · Cited by 24

Expression quantitative trait analyses to identify causal genetic variants for type 2 diabetes susceptibility

Das, S. K., & Sharma, N. (2014) · World Journal of Diabetes · doi:10.4239/wjd.v5.i2.97 · Cited by 22

Applying multi-omics data to study the genetic background of bovine respiratory disease infection in feedlot crossbred cattle

Li, J., Mukiibi, R., Jiminez, J. A., Wang, Z., Akanno, E. C., Timsit, E., & Plastow, G. S. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.1046192 · Cited by 22

DNA methylation modulated genetic variant effect on gene transcriptional regulation

Zeng, Y., Jain, R., Lam, M., Ahmed, M., Guo, H., Xu, W., Zhong, Y., Xu, W., Xu, W., & He, H. H. (2023) · Genome biology · doi:10.1186/s13059-023-03130-5 · Cited by 22

Characterization of Expression Quantitative Trait Loci in the Human Colon

Singh, T., Levine, A. P., Smith, P. J., Smith, A. M., Segal, A. W., & Barrett, J. C. (2015) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000265 · Cited by 23

Genome-wide expression quantitative trait loci analysis in asthma

Bossé, Y. (2013) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e328364e951 · Cited by 22

Gene-Gene Interaction and Functional Impact of Polymorphisms on Innate Immune Genes in Controlling Plasmodium falciparum Blood Infection Level

Basu, M., Das, T., Ghosh, A., Majumder, S., Maji, A. K., Kanjilal, S. D., Mukhopadhyay, I., Roychowdhury, S., Banerjee, S., & Sengupta, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046441 · Cited by 22

Genetics of human gene expression

Stranger, B. E., & Raj, T. (2013) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2013.10.004 · Cited by 23

The Genetics of Sudden Cardiac Death

Arking, D. E., & Sotoodehnia, N. (2012) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-090711-163841 · Cited by 22

Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis

Yau, A. C. Y., Tuncel, J., Haag, S., Norin, U., Houtman, M., Padyukov, L., & Holmdahl, R. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1600567113 · Cited by 22

Genetic variation contributes to gene expression response in ischemic stroke: an eQTL study

Amini, H., Shroff, N., Stamova, B. S., Ferino, E., Carmona-Mora, P., Zhan, X., Sitorus, P., Hull, H., Jickling, G. C., Sharp, F. R., et al. (2020) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51154 · Cited by 22

Gene Set Analysis and Network Analysis for Genome-Wide Association StudiesPreprint

Pedroso, I., & Breen, G. D. (2011) · Cold Spring Harbor Protocols · doi:10.1101/pdb.top065581 · Cited by 22

Computational Tools for Discovery and Interpretation of Expression Quantitative Trait Loci

Wright, F. A., Shabalin, A. A., & Rusyn, I. (2012) · Pharmacogenomics · doi:10.2217/pgs.11.185 · Cited by 22

Application of genetic/genomic approaches to allergic disorders

Baye, T. M., Martin, L. J., & Hershey, G. K. K. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.05.025 · Cited by 22

Genetics of Complex Airway Disease

Cookson, W., & Moffatt, M. F. (2011) · Proceedings of the American Thoracic Society · doi:10.1513/pats.201101-003ms · Cited by 21

A genome‐wide association study in Caucasian women suggests the involvement of HLA genes in the severity of facial solar lentigines

Laville, V., Clerc, S. L., Ezzedine, K., Jdid, R., Taing, L., Labib, T., Coulonges, C., Ulveling, D., Carpentier, W., Galan, P., et al. (2016) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12502 · Cited by 21

Post-operative atrial fibrillation examined using whole-genome RNA sequencing in human left atrial tissue

Sigurdsson, M. I., Saddic, L., Heydarpour, M., Chang, T.-W., Shekar, P., Aranki, S. F., Couper, G. S., Shernan, S. K., Muehlschlegel, J. D., & Body, S. C. (2017) · BMC Medical Genomics · doi:10.1186/s12920-017-0270-5 · Cited by 21

Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation

Li, Y., McGrail, D. J., Xu, J., Mills, G. B., Sahni, N., & Yi, S. S. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.05.002 · Cited by 21

The second genome: Effects of the mitochondrial genome on cancer progression

Scheid, A. D., Beadnell, T. C., & Welch, D. R. (2019) · Advances in cancer research · doi:10.1016/bs.acr.2019.01.001 · Cited by 21

A 16q22.1 variant confers susceptibility to colorectal cancer as a distal regulator of ZFP90

Yu, C., Han, J., Zhang, J., Jiang, P., Shen, C., Guo, F., Tang, J., Yan, T., Tian, X., Zhu, X., et al. (2019) · Oncogene · doi:10.1038/s41388-019-1055-4 · Cited by 21

Evolution of approaches to identify melanoma missing heritability

Dalmasso, B., & Ghiorzo, P. (2020) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2020.1738221 · Cited by 21

Variation in the Untranslated Genome and Susceptibility to Infections

Ramsuran, V., Ewy, R., Nguyen, H., & Kulkarni, S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02046 · Cited by 21

Annotating individual human genomes

Torkamani, A., Zeeland, A. A. S., Topol, E. J., & Schork, N. J. (2011) · Genomics · doi:10.1016/j.ygeno.2011.07.006 · Cited by 21

Genetics of Psychiatric Disorders Methods: Molecular Approaches

Avramopoulos, D. (2010) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2009.12.006 · Cited by 21

Differential regulation enrichment analysis via the integration of transcriptional regulatory network and gene expression data

Ma, S., Jiang, T., & Jiang, R. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu672 · Cited by 20

Systems genetics reveals key genetic elements of drought induced gene regulation in diploid potato

van Muijen, D., Anithakumari, A. M., Maliepaard, C. A., Visser, R. G. F., & van der Linden, C. G. (2016) · Plant Cell & Environment · doi:10.1111/pce.12744 · Cited by 24

Personalized approach to childhood obesity: Lessons from gut microbiota and omics studies. Narrative review and insights from the 29th European childhood obesity congress

Gawlik, A., Salonen, A., Jian, C., Yanover, C., Antosz, A., Shmoish, M., Wasniewska, M. G., Bereket, A., Wudy, S. A., Hartmann, M. F., et al. (2021) · Pediatric Obesity · doi:10.1111/ijpo.12835 · Cited by 20

Behçet's: A Disease or a Syndrome? Answer from an Expression Profiling Study

Oğuz, A. K., Yılmaz, S. T., Oygür, Ç. Ş., Çandar, T., Sayın, İ., Kılıçoğlu, B., Ergün, İ., Ateş, A., Özdağ, H., & Akar, N. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149052 · Cited by 20

SPINK6 inhibits human airway serine proteases and restricts influenza virus activation

Wang, D., Li, C., Chiu, M. C., Yu, Y., Liu, X., Zhao, X., Huang, J., Cheng, Z., Yuan, S., Poon, V. K., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202114485 · Cited by 19

A tool for RNA sequencing sample identity check

Huang, J., Chen, J., Lathrop, M. G., & Liang, L. (2013) · Bioinformatics · doi:10.1093/bioinformatics/btt155 · Cited by 19

Genetic indicators and susceptibility to osteoarthritis: Figure 1

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Human neuronal changes in brain edema and increased intracranial pressure

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