Moffatt, Miriam F.

Genetic studies of body mass index yield new insights for obesity biology

Study, T. L. C., Locke, A. E., The ADIPOGen Consortium, The AGEN-BMI Working Group, The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The, G. L. G. C., The, I. C. B. P., The MAGIC Investigators, The MuTHER Consortium, et al. (2015) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 4,534

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Salter, S. J., Cox, M. J., Turek, E. M., Calus, S. T., Cookson, W. O., Moffatt, M. F., Turner, P., Parkhill, J., Loman, N. J., & Walker, A. W. (2014) · BMC Biology

Genomics and Phylogenetic StudiesGut microbiota and health

Cited by 3,463

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

MAGIC, Speliotes, E. K., on behalf of Procardis Consortium, Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,912

New genetic loci link adipose and insulin biology to body fat distribution

The ADIPOGen Consortium, Shungin, D., The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The GEFOS Consortium, The GENIE Consortium, The, G. L. G. C., The, I. C. B. P., The International Endogene Consortium, Study, T. L. C., et al. (2015) · Nature

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,580

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

MAGIC, Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 931

Mapping complex disease traits with global gene expression

Cookson, W., Liang, L., Abecasis, G., Moffatt, M., & Lathrop, M. (2009) · Nature Reviews Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 849

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis

Fingerlin, T. E., Murphy, E., Zhang, W., Peljto, A. L., Brown, K. K., Steele, M. P., Loyd, J. E., Cosgrove, G. P., Lynch, D., Groshong, S., et al. (2013) · Nature Genetics

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisGenetic Associations and Epidemiology

Cited by 809

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Berndt, S. I., Gustafsson, S., Mägi, R., Ganna, A., Wheeler, E., Feitosa, M. F., Justice, A. E., Monda, K. L., Croteau-Chonka, D. C., Day, F. R., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 646

The role of bacteria in the pathogenesis and progression of idiopathic pulmonary fibrosis

Molyneaux, P. L., Cox, M. J., Willis-Owen, S. A. G., Mallia, P., Russell, K. E., Russell, A.-M., Murphy, E., Johnston, S. L., Schwartz, D. A., Wells, A. U., et al. (2014) · American Journal of Respiratory and Critical Care Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 567

Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease

Molyneaux, P. L., Mallia, P., Cox, M. J., Footitt, J., Willis-Owen, S. A. G., Homola, D., Trujillo-Torralbo, M.-B., Elkin, S., Kon, O. M., Cookson, W. O. C., et al. (2013) · American Journal of Respiratory and Critical Care Medicine

Chronic Obstructive Pulmonary Disease (COPD) ResearchOral microbiology and periodontitis research

Cited by 390

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Respiratory disease following viral lung infection alters the murine gut microbiota

Groves, H. T., Cuthbertson, L., James, P., Moffatt, M. F., Cox, M. J., & Tregoning, J. S. (2018) · Frontiers in Immunology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 258

Dysbiosis anticipating necrotizing enterocolitis in very premature infants

Sim, K., Shaw, A. G., Randell, P., Cox, M. J., McClure, Z. E., Li, M.-S., Haddad, M., Langford, P. R., Cookson, W. O. C. M., Moffatt, M. F., et al. (2015) · Clinical Infectious Diseases

Infant Nutrition and HealthGut microbiota and health

Cited by 224

An epigenome-wide association study of total serum immunoglobulin E concentration

Liang, L., Willis-Owen, S. A. G., Laprise, C., Wong, K. C. C., Davies, G. A., Hudson, T. J., Binia, A., Hopkin, J. M., Yang, I. V., Grundberg, E., et al. (2015) · Nature

Epigenetics and DNA MethylationAsthma and respiratory diseases

Cited by 213

Validation of a 52-gene risk profile for outcome prediction in patients with idiopathic pulmonary fibrosis: an international, multicentre, cohort study

Herazo-Maya, J. D., Sun, J., Molyneaux, P. L., Li, Q., Villalba, J. A., Tzouvelekis, A., Lynn, H., Juan-Guardela, B. M., Risquez, C., Osorio, J. C., et al. (2017) · The Lancet Respiratory Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisOccupational and environmental lung diseases

Cited by 175

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

Esparza-Gordillo, J., Schaarschmidt, H., Liang, L., Cookson, W., Bauerfeind, A., Lee-Kirsch, M.-A., Nemat, K., Henderson, J., Paternoster, L., Harper, J. I., et al. (2013) · Journal of Allergy and Clinical Immunology

Dermatology and Skin DiseasesAsthma and respiratory diseases

Cited by 107

Late-onset bloodstream infection and perturbed maturation of the gastrointestinal microbiota in premature infants

Shaw, A. G., Sim, K., Randell, P., Cox, M. J., McClure, Z. E., Li, M.-S., Donaldson, H., Langford, P. R., Cookson, W. O. C. M., Moffatt, M. F., et al. (2015) · PLoS ONE

Neonatal and Maternal InfectionsGut microbiota and health

Cited by 96

Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators

Edwards, M. R., Saglani, S., Schwarze, J., Skevaki, C., Smith, J. A., Ainsworth, B., Almond, M., Andreakos, E., Belvisi, M. G., Chung, K. F., et al. (2017) · European Respiratory Journal

Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 55

Novel childhood asthma genes interact with in utero and early-life tobacco smoke exposure

Scholtens, S., Postma, D. S., Moffatt, M. F., Panasevich, S., Granell, R., Henderson, A. J., Melén, E., Nyberg, F., Pershagen, G., Jarvis, D., et al. (2014) · Journal of Allergy and Clinical Immunology

Asthma and respiratory diseasesGenetic Associations and Epidemiology

Cited by 51

COPD Is Accompanied by Co-Ordinated Transcriptional Perturbation in the Quadriceps Affecting the Mitochondria and Extracellular Matrix

Willis-Owen, S. A. G., Thompson, A., Kemp, P. R., Polkey, M. I., Cookson, W. O. C. M., Moffatt, M. F., & Natanek, S. A. (2018) · Scientific Reports

Muscle Physiology and DisordersChronic Obstructive Pulmonary Disease (COPD) Research

Cited by 42

Metabolomic, transcriptomic and genetic integrative analysis reveals important roles of adenosine diphosphate in haemostasis and platelet activation in non‐small‐cell lung cancer

Hoang, L. T., Domingo‐Sabugo, C., Starren, E. S., Willis‐Owen, S. A. G., Morris‐Rosendahl, D. J., Nicholson, A. G., Cookson, W. O. C. M., & Moffatt, M. F. (2019) · Molecular Oncology

Cancer, Hypoxia, and MetabolismBioinformatics and Genomic Networks

Cited by 39

DNA methylation within melatonin receptor 1A (MTNR1A) mediates paternally transmitted genetic variant effect on asthma plus rhinitis

Sarnowski, C., Laprise, C., Malerba, G., Moffatt, M. F., Dizier, M.-H., Morin, A., Vincent, Q. B., Rohde, K., Esparza-Gordillo, J., Margaritte-Jeannin, P., et al. (2016) · Journal of Allergy and Clinical Immunology

Asthma and respiratory diseasesGenetic Associations and Epidemiology

Cited by 35

A Polymorphism Affecting MYB Binding within the Promoter of the PDCD4 Gene is Associated with Severe Asthma in Children

Binia, A., Van Stiphout, N., Liang, L., Michel, S., Bhavsar, P. K., Fan Chung, K., Brightling, C. E., Barnes, P. J., Kabesch, M., Bush, A., et al. (2013) · Human Mutation

Asthma and respiratory diseasesGenetic Associations and Epidemiology

Cited by 24

Manipulation of dipeptidylpeptidase 10 in mouse and human in vivo and in vitro models indicates a protective role in asthma

Zhang, Y., Poobalasingam, T., Yates, L. L., Walker, S. A., Taylor, M. S., Chessum, L., Harrison, J., Tsaprouni, L., Adcock, I. M., Lloyd, C. M., et al. (2018) · Disease Models & Mechanisms

Asthma and respiratory diseasesOccupational exposure and asthma

Cited by 15