The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Causes and consequences of microRNA dysregulation in cancer
Open accessAbstract
Over the past several years it has become clear that alterations in the expression of microRNA (miRNA) genes contribute to the pathogenesis of most — if not all — human malignancies. These alterations can be caused by various mechanisms, including deletions, amplifications or mutations involving miRNA loci, epigenetic silencing or the dysregulation of transcription factors that target specific miRNAs. Because malignant cells show dependence on the dysregulated expression of miRNA genes, which in turn control or are controlled by the dysregulation of multiple protein-coding oncogenes or tumour suppressor genes, these small RNAs provide important opportunities for the development of future miRNA-based therapies.
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Cites
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Self-citationIdentification of Novel Genes Coding for Small Expressed RNAs
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Cited by
Non-coding RNAs in human disease
Esteller, M. (2011) · Nature Reviews Genetics · doi:10.1038/nrg3074 · Cited by 4,825
Immune checkpoint inhibitors: recent progress and potential biomarkers
Darvin, P., Toor, S. M., Sasidharan Nair, V., & Elkord, E. (2018) · Experimental & Molecular Medicine · doi:10.1038/s12276-018-0191-1 · Cited by 2,035
Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells
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MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response
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Self-citationCirculating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis
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Metadata
- Authors
- Croce, C. M.
- Venue
- Nature Reviews Genetics
- Published
- 2009-10
- Volume
- 10
- Issue
- 10
- Pages
- 704-714
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W2008945738
- Cited by
- 2,998
- References
- 13
- FWCI
- 8.58
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.