The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Transcription as a source of genome instability
Open accessAbstract
Alterations in genome sequence and structure contribute to somatic disease, affect the fitness of subsequent generations and drive evolutionary processes. The crucial roles of highly accurate replication and efficient repair in maintaining overall genome integrity are well-known, but the more localized stability costs that are associated with transcribing DNA into RNA molecules are less appreciated. Here we review the diverse ways in which the essential process of transcription alters the underlying DNA template and thereby modifies the genetic landscape.
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Cites
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“In addition, ChIP–chip analysis has uncovered sequences that have G4-DNA-forming potential as preferential sites of yeast Pif1 association and as sites of replication slowin”
BackgroundMutagenic Processing of Ribonucleotides in DNA by Yeast Topoisomerase I
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Cited by
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
Crosetto, N., Mitra, A., Silva, M. J., Bienko, M., Dojer, N., Wang, Q., Karaca, E., Chiarle, R., Skrzypczak, M., Ginalski, K., et al. (2013) · Nature Methods · doi:10.1038/nmeth.2408 · Cited by 465
RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity
Pefanis, E., Wang, J., Rothschild, G., Lim, J., Kazadi, D., Sun, J., Federation, A., Chao, J., Elliott, O., Liu, Z.-P., et al. (2015) · Cell · doi:10.1016/j.cell.2015.04.034 · Cited by 464
The genomics of oxidative DNA damage, repair, and resulting mutagenesis
Poetsch, A. R. (2020) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2019.12.013 · Cited by 420
New Mechanistic and Functional Insights into DNA Topoisomerases
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Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells
Wei, P.-C., Chang, A. N., Kao, J., Du, Z., Meyers, R. M., Alt, F. W., & Schwer, B. (2016) · Cell · doi:10.1016/j.cell.2015.12.039 · Cited by 280
Metadata
- Authors
- Kim, N., & Jinks-Robertson, S.
- Venue
- Nature Reviews Genetics
- Published
- 2012-02-14
- Volume
- 13
- Issue
- 3
- Pages
- 204-214
- ISSN
- 1471-0056 (ISSN-L)
- 1471-0064
- OpenAlex
- W1978189157
- Cited by
- 305
- References
- 10
- FWCI
- 1.96
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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