The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Specialized pro-resolving mediators: endogenous regulators of infection and inflammation
Open accessAbstract
Specialized pro-resolving mediators (SPMs) are enzymatically derived from essential fatty acids and have important roles in orchestrating the resolution of tissue inflammation — that is, catabasis. Host responses to tissue infection elicit acute inflammation in an attempt to control invading pathogens. SPMs are lipid mediators that are part of a larger family of pro-resolving molecules, which includes proteins and gases, that together restrain inflammation and resolve the infection. These immunoresolvents are distinct from immunosuppressive molecules as they not only dampen inflammation but also promote host defence. Here, we focus primarily on SPMs and their roles in lung infection and inflammation to illustrate the potent actions these mediators play in restoring tissue homeostasis after an infection.
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Cites
Pro-resolving lipid mediators are leads for resolution physiology
Serhan, C. N. (2014) · Nature · doi:10.1038/nature13479 · Cited by 3,041
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Lipid mediator class switching during acute inflammation: signals in resolution
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Self-citationInnate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
Monticelli (2011) · PubMed · doi:10.1031/ni.2131 · Cited by 1,286
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Resolvins and protectins in inflammation resolution
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Maresins: Novel macrophage mediators with potent antiinflammatory and proresolving actions
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Cited by
Calder, P., Carr, A., Gombart, A., & Eggersdorfer, M. (2020) · Nutrients · doi:10.3390/nu12041181 · Cited by 972
Serhan, C. N. (2017) · The FASEB Journal · doi:10.1096/fj.201601222r · Cited by 555
López-Otín, C., & Kroemer, G. (2021) · Cell · doi:10.1016/j.cell.2020.11.034 · Cited by 499
Lipids and Alzheimer’s Disease
Kao, Y.-C., Ho, P.-C., Tu, Y.-K., Jou, I.-M., & Tsai, K.-J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21041505 · Cited by 485
Yin, F. (2023) · The FEBS Journal · doi:10.1111/febs.16344 · Cited by 441
Metadata
- Authors
- Basil, M. C., & Levy, B. D.
- Venue
- Nature Reviews Immunology
- Published
- 2015-12-21
- Volume
- 16
- Issue
- 1
- Pages
- 51-67
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2198808464
- Cited by
- 791
- References
- 23
- FWCI
- 5.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
