The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Converging roles of caspases in inflammasome activation, cell death and innate immunity
Open accessAbstract
Inflammatory and apoptotic caspases are central players in inflammation and apoptosis, respectively. However, recent studies have revealed that these caspases have functions beyond their established roles. In addition to mediating cleavage of the inflammasome-associated cytokines interleukin-1β (IL-1β) and IL-18, inflammatory caspases modulate distinct forms of programmed cell death and coordinate cell-autonomous immunity and other fundamental cellular processes. Certain apoptotic caspases assemble structurally diverse and dynamic complexes that direct inflammasome and interferon responses to fine-tune inflammation. In this Review, we discuss the expanding and interconnected roles of caspases that highlight new aspects of this family of cysteine proteases in innate immunity.
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Cited by
Mitochondrial DNA in innate immune responses and inflammatory pathology
West, A. P., & Shadel, G. S. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.21 · Cited by 1,115
Kuriakose, T., Man, S. M., Subbarao Malireddi, R. K., Karki, R., Kesavardhana, S., Place, D. E., Neale, G., Vogel, P., & Kanneganti, T.-D. (2016) · Science Immunology · doi:10.1126/sciimmunol.aag2045 · Cited by 818
Self-citationRole of pyroptosis in inflammation and cancer
Wei, X., Xie, F., Zhou, X., Wu, Y., Yan, H., Liu, T., Huang, J., Wang, F., Zhou, F., & Zhang, L. (2022) · Cellular & Molecular Immunology · doi:10.1038/s41423-022-00905-x · Cited by 699
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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
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Metadata
- Authors
- Man, S. M., & Kanneganti, T.-D.
- Venue
- Nature Reviews Immunology
- Published
- 2015-12-14
- Volume
- 16
- Issue
- 1
- Pages
- 7-21
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2201316930
- Cited by
- 701
- References
- 40
- FWCI
- 3.78
- Type
- journal article
- Language
- en
- Open access
- green
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