TREMs in the immune system and beyond

Colonna, Marco·2003·Nature Reviews Immunology

DOI 10.1038/nri1106

Cited by (700)

Items 201–300 of 700

Induction of triggering receptor expressed on myeloid cells 1 in murine resident peritoneal macrophages by monosodium urate monohydrate crystals
Yousuke Murakami, Tohru Akahoshi, Izumi Hayashi, Hirahito Endo, Shinichi Kawai, Matsuhisa Inoue, Hirobumi Kondo, Hidero Kitasato · 2006 · Arthritis & Rheumatism
Trem-Like Transcript 2 Is Expressed on Cells of the Myeloid/Granuloid and B Lymphoid Lineage and Is Up-Regulated in Response to Inflammation
Rodney Glenn King, Brantley R. Herrin, Louis B. Justement · 2006 · The Journal of Immunology
A genetic basis for the “Adonis” phenotype of low adiposity and strong bones
Geoffrey Bates Johnson, B. Lawrence Riggs, Jeffrey L. Platt · 2004 · The FASEB Journal
TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis
Sheng-Lan Zhou, Chen‐Chen Tan, Xiao‐He Hou, Xi‐Peng Cao, Lan Tan, Jin‐Tai Yu · 2019 · Journal of Alzheimer s Disease
Tuning of macrophage responses by Stat3-inducing cytokines: molecular mechanisms and consequences in infection
Roland Lang · 2005 · Immunobiology
Nasu–Hakola disease and primary microglial dysfunction
Bianchin, Marino M., Martin, Kelin C., de Souza, Ana C., de Oliveira, Marina A., de Mello Rieder, Carlos R. · 2010 · Nature Reviews Neurology
Lipopolysaccharide-Induced Up-Regulation of Triggering Receptor Expressed on Myeloid Cells-1 Expression on Macrophages Is Regulated by Endogenous Prostaglandin E2
Yousuke Murakami, Hitoshi Kohsaka, Hidero Kitasato, Tohru Akahoshi · 2007 · The Journal of Immunology
Diagnostic value of urine sTREM-1 for sepsis and relevant acute kidney injuries: a prospective study
Longxiang Su, Lin Feng, Jie Zhang, Yongjiu Xiao, Yanhong Jia, Peng Yan, Dan Feng, Lixin Xie · 2011 · Critical Care
Tumor necrosis factor-α regulates triggering receptor expressed on myeloid cells-1-dependent matrix metalloproteinases in the carotid plaques of symptomatic patients with carotid stenosis
Velidi H. Rao, Vikrant Rai, Samantha Stoupa, Saravanan Subramanian, Devendra K. Agrawal · 2016 · Atherosclerosis
Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells
Kaori Endo‐Umeda, Makoto Makishima · 2019 · International Journal of Molecular Sciences
Review: The genetics of A lzheimer's disease; putting flesh on the bones
Christopher Medway, Kevin Morgan · 2013 · Neuropathology and Applied Neurobiology
Porphyromonas gingivalis Regulates TREM-1 in Human Polymorphonuclear Neutrophils via Its Gingipains
Nagihan Bostancı, Thomas Thurnheer, Joseph Aduse‐Opoku, Michael A. Curtis, Annelies Sophie Zinkernagel, Georgios N. Belibasakis · 2013 · PLoS ONE
The Structure of the Extracellular Domain of Triggering Receptor Expressed on Myeloid Cells Like Transcript-1 and Evidence for a Naturally Occurring Soluble Fragment*
James L. Gattis, A. Washington, M. Chisholm, L. Quigley, A. Szyk, D. McVicar, J. Lubkowski · 2006 · Journal of Biological Chemistry
TREM-2 Promotes Host Resistance Against Pseudomonas aeruginosa Infection by Suppressing Corneal Inflammation via a PI3K/Akt Signaling Pathway
Mingxia Sun, Min Zhu, Kang Chen, Xinxin Nie, Qiuchan Deng, Linda D. Hazlett, Yongjian Wu, Meiyu Li, Minhao Wu, Xi Huang · 2013 · Investigative Ophthalmology & Visual Science
Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation
Toshihiro Matsukawa, Kumi Izawa, Masamichi Isobe, Mariko Takahashi, Akie Maehara, Yoshinori Yamanishi, Ayako Kaitani, Ko Okumura, Takanori Teshima, Toshio Kitamura et al. · 2015 · Gut
New Insight in LPS Antagonist
Angela Ianaro, Mariaroberta Tersigni, Fulvio D’Acquisto · 2009 · Mini-Reviews in Medicinal Chemistry
MYD88‐dependent and ‐independent activation of TREM‐1 via specific TLR ligands
Heng Zheng, Caitlin A. Heiderscheidt, Myung Joo, Xeipei Gao, Nebojša Nick Knežević, Dolly Mehta, Ruxana T. Sadikot · 2009 · European Journal of Immunology
Lack of Genetic Association Between TREM2 and Late-Onset Alzheimer's Disease in a Japanese Population
Miyashita, Akinori, Wen, Yanan, Kitamura, Nobutaka, Matsubara, Etsuro, Kawarabayashi, Takeshi, Shoji, Mikio, Tomita, Naoki, Furukawa, Katsutoshi, Arai, Hiroyuki, Asada, Takashi et al. · 2014 · Journal of Alzheimer’s Disease
Recent advances in crystal-induced acute inflammation
Tohru Akahoshi, Yousuke Murakami, Hidero Kitasato · 2007 · Current Opinion in Rheumatology
Divergent Neuroinflammatory Regulation of Microglial TREM Expression and Involvement of NF-κB
Rosie Owens, Kathleen Grabert, Claire Linzi Davies, Alessio Alfieri, Jack Perry Antel, Luke M. Healy, Barry W. McColl · 2017 · Frontiers in Cellular Neuroscience
Molecular Characterization of a Novel Immune Receptor Restricted to the Monocytic Lineage
Helena Aguilar, Damiana Álvarez‐Errico, Andrés C. García‐Montero, Alberto Órfão, Joan Sayós, Miguel López‐Botet · 2004 · The Journal of Immunology
Transcriptome analysis of airborne PM 2.5-induced detrimental effects on human keratinocytes
Kim, Hyoung-June, Bae, Il-Hong, Son, Eui Dong, Park, Juyearl, Cha, Nari, Na, Hye-Won, Jung, Changjo, Go, You-Seak, Kim, Dae-Yong, Lee, Tae Ryong et al. · 2017 · Toxicology Letters
Innate sensing of mechanical properties of brain tissue by microglia
Pinar Ayata, Anne Schaefer · 2020 · Current Opinion in Immunology
Functional Analysis of Activating Receptor LMIR4 as a Counterpart of Inhibitory Receptor LMIR3
Kumi Izawa, Jiro Kitaura, Yoshinori Yamanishi, Takayuki Matsuoka, Toshihiko Oki, Fumi Shibata, Hidetoshi Kumagai, Hideaki Nakajima, Mari Maeda‐Yamamoto, Jeffrey P. Hauchins et al. · 2007 · Journal of Biological Chemistry
Crystal Structure of Human Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.47Å
Matthew S. Kelker, Theodore R. Foss, Wolfgang Peti, Luc Teyton, Jeffery W. Kelly, Kurt Wüthrich A, Ian A. Wilson · 2004 · Journal of Molecular Biology
Surface and soluble triggering receptor expressed on myeloid cells-1: Expression patterns in murine sepsis
Sébastien Gibot, Frédéric Massin, Pol‐Edern Le Renard, Marie C. Béné, Gilbert Charles Faure, Pierre‐Édouard Bollaert, Bruno Lévy · 2005 · Critical Care Medicine
Crystal Structure of Mouse Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) at 1.76Å
Matthew S. Kelker, Erik Debler, Ian A. Wilson · 2004 · Journal of Molecular Biology
Translational molecular imaging and drug development in Parkinson’s disease
Ahmed Haider, Nehal H. Elghazawy, Alyaa Dawoud, Cathérine Gebhard, Thomas Wichmann, Wolfgang Sippl, Marius Christian Hoener, Ernest Arenas, Steven H. Liang · 2023 · Molecular Neurodegeneration
Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure
The Dominantly Inherited Alzheimer Network (DIAN), Li, Zeran, Del-Aguila, Jorge L., Dube, Umber, Budde, John, Martinez, Rita, Black, Kathleen, Xiao, Qingli, Cairns, Nigel J., Dougherty, Joseph D. et al. · 2018 · Genome Medicine
TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models
Edward N. Wilson, Congcong Wang, Michelle S. Swarovski, Kristy A. Zera, Hannah E. Ennerfelt, Qian Wang, Aisling M. Chaney, Esha Gauba, Javier A. Ramos Benitez, Yann Le Guen et al. · 2024 · Nature Neuroscience
CD200:CD200R-Mediated Regulation of Immunity
Reginald M. Gorczynski · 2012 · ISRN Immunology
An Activating and Inhibitory Signal from an Inhibitory Receptor LMIR3/CLM-1: LMIR3 Augments Lipopolysaccharide Response through Association with FcRγ in Mast Cells
Kumi Izawa, Jiro Kitaura, Yoshinori Yamanishi, Takayuki Matsuoka, Ayako Kaitani, Masahiro Sugiuchi, Mariko Takahashi, Akie Maehara, Yutaka Enomoto, Toshihiko Oki et al. · 2009 · The Journal of Immunology
The IREM-1 (CD300f) Inhibitory Receptor Associates with the p85α Subunit of Phosphoinositide 3-Kinase
Damiana Álvarez‐Errico, Joan Sayós, Miguel López‐Botet · 2007 · The Journal of Immunology
Evidence for TLR4 and FcRγ–CARD9 activation by cholera toxin B subunit and its direct bindings to TREM2 and LMIR5 receptors
Vongsavanh Phongsisay, Ei’ichi Iizasa, Hiromitsu Hara, Hiroki Yoshida · 2015 · Molecular Immunology
Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray study
Marcel G. M. Wolfs, Sander S. Rensen, Elinda van Dijk, Froukje Jantina Verdam, Jan-Willem M. Greve, Bahram Sanjabi, Marcel Bruinenberg, Cisca Wijmenga, Timon W. van Haeften, Wim A. Buurman et al. · 2010 · BMC Medical Genomics
Higher Peripheral TREM2 mRNA Levels Relate to Cognitive Deficits and Hippocampal Atrophy in Alzheimer’s Disease and Amnestic Mild Cognitive Impairment
Yi Jayne Tan, Adeline SL Ng, Ashwati Vipin, Joseph K.W. Lim, Russell Jude Chander, Fang Ji, Yingwei Qiu, Simon K. S. Ting, Shahul Hameed, Tih-Shih W. Lee et al. · 2017 · Journal of Alzheimer s Disease
FOXM1 network in association with TREM1 suppression regulates NET formation in diabetic foot ulcers
Andrew Phillip Sawaya, Rivka C. Stone, Spencer Mehdizadeh, Irena Pastar, Stephen D. Worrell, Nathan C. Balukoff, Mariana J. Kaplan, Marjana Tomic‐Canic, María I. Morasso · 2022 · EMBO Reports
TREM1: Activation, signaling, cancer and therapy
Chenyang Li, Chujun Cai, Dafeng Xu, Xiaoping Chen, Jia Song · 2024 · Pharmacological Research
Dual role of microglia in neuroinflammation and neurodegenerative diseases
Amir Ajoolabady, Bonglee Kim, Altaf A. Abdulkhaliq, Jun Tao Ren, Suhad Bahijri, Jaakko O. Tuomilehto, Anwar Borai, Johra Khan, Domenico Praticò · 2025 · Neurobiology of Disease
Soluble TREM-1 as a diagnostic and prognostic biomarker in patients with septic shock: an observational clinical study
Thorsten Brenner, Florian Uhle, Thomas Fleming, Matthias Josef Wieland, Thomas Schmoch, Felix C. F. Schmitt, Karsten Schmidt, Aleksandar R. Zivkovic, Thomas M. Bruckner, Markus A. Weigand et al. · 2016 · Biomarkers
Gene Expression Profiling in Blood Provides Reproducible Molecular Insights into Asthma Control
Damien C. Croteau‐Chonka, Weiliang Qiu, Fernando D. Martínez, Robert C. Strunk, Robert F. Lemanske, Andrew H. Liu, Frank D. Gilliland, Joshua Millstein, W. James Gauderman, Carole Ober et al. · 2016 · American Journal of Respiratory and Critical Care Medicine
Inflammation: major denominator of obesity, Type 2 diabetes and Alzheimer’s disease-like pathology?
Miroslava Kacířová, Anna Zmeškalová, Lucia Kořínková, Blanka Železná, Jaroslav Kuneš, Lenka Maletı́nská · 2020 · Clinical Science
Paired immunoglobulin-like receptor B regulates platelet activation
Xuemei Fan, Panlai Shi, Jing Dai, Yeling Lu, Xue Chen, Xiaoye Liu, Kandi Zhang, Xiaolin Wu, Yueping Sun, Kemin Wang et al. · 2014 · Blood
Blocking TREM-1 signaling prolongs survival of mice with Pseudomonas aeruginosa induced sepsis
Feng Wang, Shuanglin Liu, Shiji Wu, Qin Zhu, Guoping Ou, Cailin Liu, Yue Wang, Yalong Liao, Sun Ziyong · 2011 · Cellular Immunology
TREM-2 binds to lipooligosaccharides of Neisseria gonorrhoeae and is expressed on reproductive tract epithelial cells
D N Quan, M D Cooper, J L Potter, M H Roberts, H Cheng, Gary A. Jarvis · 2008 · Mucosal Immunology
Structural and Functional Heterogeneity in the CD200R Family of Immunoregulatory Molecules and their Expression at the Feto‐maternal Interface
Reginald M. Gorczynski, Zhiqi Chen, David A. Clark, Kai Yu, Lydia Lee, Joseph Nachman, Simon Y. C. Wong, Philip A. Marsden · 2004 · American Journal of Reproductive Immunology
Tea polyphenols inhibit the activation of NF-κB and the secretion of cytokines and matrix metalloproteinases by macrophages stimulated with Fusobacterium nucleatum
Amel Ben Lagha, Daniel Grenier · 2016 · Scientific Reports
Mapping and kinetics of microglia/neuron cell-to-cell contacts in the 6-OHDA murine model of Parkinson's disease
Angélique Virgone‐Carlotta, Josselin Uhlrich, Muhammad Numan Akram, Denis Ressnikoff, Fabrice Chrétien, Chantal Domenget, Romain Kroum Gherardi, Geneviève Despars, Pierre Jurdic, Jérôme Honnorat et al. · 2013 · Glia
Microglia Are Mediators of Borrelia burgdorferi–Induced Apoptosis in SH-SY5Y Neuronal Cells
Tereance Alixandre Myers, Deepak Kaushal, Mario T. Philipp · 2009 · PLoS Pathogens
Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE ε4
Margeta, Milica A., Letcher, Sophia M., Igo, Robert P., Cooke Bailey, Jessica N., Pasquale, Louis R., Haines, Jonathan L., Butovsky, Oleg, Wiggs, Janey L., for the NEIGHBORHOOD consortium · 2020 · Investigative Opthalmology & Visual Science
Role of Microglia in Modulating Adult Neurogenesis in Health and Neurodegeneration
Mohammed Al‐Onaizi, Alaa Al-Khalifah, Dalal Qasem, Ayman ElAli · 2020 · International Journal of Molecular Sciences
DIgR2, dendritic cell-derived immunoglobulin receptor 2, is one representative of a family of IgSF inhibitory receptors and mediates negative regulation of dendritic cell-initiated antigen-specific T-cell responses
Liyun Shi, Kun Luo, Dajing Xia, Taoyong Chen, Guoyou Chen, Yingming Jiang, Nan Li, Xuetao Cao · 2006 · Blood
TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
Ankita Dabla, Yi Chu Liang, Nusrah Rajabalee, Courtney L. Irwin, Carolyn G. J. Moonen, Jessie V. Willis, Stefania Berton, Jim Sun · 2022 · mBio
Chicken Ig-Like Receptor B2, a Member of a Multigene Family, Is Mainly Expressed on B Lymphocytes, Recruits Both Src Homology 2 Domain Containing Protein Tyrosine Phosphatase (SHP)-1 and SHP-2, and Inhibits Proliferation
Birgit C. Viertlboeck, Richard P. M. A. Crooijmans, Martien A. M. Groenen, Thomas Göbel · 2004 · The Journal of Immunology
The characteristics and pivotal roles of triggering receptor expressed on myeloid cells-1 in autoimmune diseases
Sheng Gao, Yongdong Yi, Guojun Xia, Chengyang Yu, Chenmin Ye, Fuyang Tu, Leibin Shen, Wenqian Wang, Chunyan Hua · 2018 · Autoimmunity Reviews
A Novel Recognition System for MHC Class I Molecules Constituted by PIR
Toshiyuki Takai · 2005 · Advances in immunology
Analysis of mouse LMIR5/CLM-7 as an activating receptor: differential regulation of LMIR5/CLM-7 in mouse versus human cells
Yoshinori Yamanishi, Jiro Kitaura, Kumi Izawa, Takayuki Matsuoka, Toshihiko Oki, Lu Yang, Fumi Shibata, Satoshi Yamazaki, Hidetoshi Kumagai, Hideaki Nakajima et al. · 2007 · Blood
Development and maintenance of the brain’s immune toolkit: microglia and non-parenchymal brain macrophages
Lopez‐Atalaya, Jose P., Askew, Katharine E., Sierra, Amanda, Gomez‐Nicola, Diego · 2018 · Developmental Neurobiology
The Triggering Receptor Expressed on Myeloid Cells 2: “TREM-ming” the Inflammatory Component Associated with Alzheimer's Disease
Troy T. Rohn · 2013 · Oxidative Medicine and Cellular Longevity
Triggering receptor expressed in myeloid cells 2 (TREM2) trafficking in microglial cells: Continuous shuttling to and from the plasma membrane regulated by cell stimulation
Ilaria Prada, Gabriela Naum-Onganı́a, Cecilia Buonsanti, Paola Panina‐Bordignon, Jacopo Meldolesi · 2006 · Neuroscience
TREM-2 serves as a negative immune regulator through Syk pathway in an IL-10 dependent manner in lung cancer
Yinan Yao, Hequan Li, Junjun Chen, Weiyi Xu, Guangdie Yang, Zhang Bao, Dajing Xia, Guohua Lu, Shuwen Hu, Jianying Zhou · 2016 · Oncotarget
Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease
Sylvia E. Perez, Muhammad Nadeem, Bin He, Jennifer C. Miguel, Michael H. Malek‐Ahmadi, Kewei Chen, Elliott Jay Mufson · 2017 · Neurobiology of Aging
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage
Sanna H. Loppi, Natalia Kołosowska, Olli K. Kärkkäinen, Paula Korhonen, Mikko T. Huuskonen, Alexandra Grubman, Hiramani Dhungana, Sara Wojciechowski, Yuriy Pomeshchik, M. Giordano et al. · 2018 · Brain Behavior and Immunity
Profiles of structural heterogeneity in native lipooligosaccharides of Neisseria and cytokine induction
Constance M. John, Mingfeng Liu, Gary A. Jarvis · 2008 · Journal of Lipid Research
Ligation of the FcRγ Chain-Associated Human Osteoclast-Associated Receptor Enhances the Proinflammatory Responses of Human Monocytes and Neutrophils
Estelle Merck, Claude Gaillard, Mathieu Scuiller, Patrizia Scapini, Marco Antonio Cassatella, Giorgio Trinchieri, Elizabeth E. M. Bates · 2006 · The Journal of Immunology
The Functions and Phenotypes of Microglia in Alzheimer’s Disease
Risako Fujikawa, Makoto Tsuda · 2023 · Cells
CD85j (Leukocyte Ig-Like Receptor-1/Ig-Like Transcript 2) Inhibits Human Osteoclast-Associated Receptor-Mediated Activation of Human Dendritic Cells
Claudya Tenca, Andrea Carlo Merlo, Estelle Merck, Elizabeth E. M. Bates, Danièle Saverino, Rita Simone, Daniela Zarcone, Giorgio Trinchieri, Carlo Enrico Grossi, Ermanno Ciccone · 2005 · The Journal of Immunology
Differential Modulation of TREM2 Protein during Postnatal Brain Development in Mice
Mariela Chertoff, Kalpana Shrivastava, Berta González, Laia Acarín, Lydia Giménez‐Llort · 2013 · PLoS ONE
TREM-1 Expression Is Increased in Human Placentas From Severe Early-Onset Preeclamptic Pregnancies Where It May Be Involved in Syncytialization
Ratana Lim, Gillian Barker, Martha Lappas · 2013 · Reproductive Sciences
The Role of TREM2 in Alzheimer’s Disease and Other Neurological Disorders
Faris Yaghmoor · 2014 · Journal of Alzheimer’s Disease & Parkinsonism
The Alzheimer's Disease-Associated R47H Variant of TREM2 Has an Altered Glycosylation Pattern and Protein Stability
Ji‐Seon Park, In Jung Ji, Dong‐Hou Kim, Hyun Joo An, Seung‐Yong Yoon · 2017 · Frontiers in Neuroscience
A critical role for DAP10 and DAP12 in CD8+ T cell–mediated tissue damage in large granular lymphocyte leukemia
Xianghong Chen, Fanqi Bai, Lubomir Sokol, Junmin Zhou, Amy Ren, Jeffrey S. Painter, Jinhong Liu, David Andrew Sallman, Y. Ann Chen, Jeffrey A. Yoder et al. · 2008 · Blood
Two macrophages, osteoclasts and microglia: from development to pleiotropy
Ji‐Won Lee, In‐Hee Lee, Tadahiro Iimura, Sek Won Kong · 2021 · Bone Research
TREM-2 is a sensor and activator of T cell response in SARS-CoV-2 infection
Yongjian Wu, Manni Wang, Huan Yin, Siqi Ming, Xingyu Li, Guanmin Jiang, Ye Liu, Pei‐Hui Wang, Guangde Zhou, Lei Liu et al. · 2021 · Science Advances
CD300 antigen like family member G: A novel Ig receptor like protein exclusively expressed on capillary endothelium
Hiroyuki Takatsu, Koji Hase, Masumi Ohmae, Sayaka Ohshima, Koji Hashimoto, Naoko Taniura, Akitsugu Yamamoto, Hiroshi Ohno · 2006 · Biochemical and Biophysical Research Communications
Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells
Tamara Brckalo, Federica Calzetti, Begoña Pérez‐Cabezas, Francesc Enric Borràs, Marco Antonio Cassatella, Miguel López‐Botet · 2009 · European Journal of Immunology
TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice
Jiang, Teng, Wan, Yu, Zhang, Ying-Dong, Zhou, Jun-Shan, Gao, Qing, Zhu, Xi-Chen, Shi, Jian-Quan, Lu, Huan, Tan, Lan, Yu, Jin-Tai · 2017 · Molecular Neurobiology
Resveratrol attenuates the pathogenic and inflammatory properties of Porphyromonas gingivalis
Amel Ben Lagha, Elisoa Andrian, Daniel Grenier · 2019 · Molecular Oral Microbiology
Channel catfish leukocyte immune-type receptors contain a putative MHC class I binding site
James L. Stafford, Eva Bengtén, Louis Du Pasquier, Norman W. Miller, Melanie Wilson · 2006 · Immunogenetics
Differential Regulation of DAP12 and Molecules Associated with DAP12 during Host Responses to Mycobacterial Infection
Naoko Aoki, Anna Zganiacz, Peter J. Margetts, Zhou Xing · 2004 · Infection and Immunity
Harnessing Immunoproteostasis to Treat Neurodegenerative Disorders
Golde, Todd E. · 2019 · Neuron
TREM2 analysis and increased risk of Alzheimer's disease
Deana Finelli, Sara J. Rollinson, Jenny Harris, Matthew S. Jones, Anna M. T. Richardson, Alexander Gerhard, Julie S. Snowden, David M. A. Mann, Stuart M. Pickering-Brown · 2014 · Neurobiology of Aging
Alzheimer’s Disease: From Genetic Variants to the Distinct Pathological Mechanisms
Qiying Sun, Nina Xie, Beisha Tang, Rena Li, Yong Shen · 2017 · Frontiers in Molecular Neuroscience
The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L
Birgit C. Viertlboeck, Ramona Schmitt, Thomas Göbel · 2006 · Immunogenetics
A Novel Activating Chicken IgY FcR Is Related to Leukocyte Receptor Complex (LRC) Genes but Is Located on a Chromosomal Region Distinct from the LRC and FcR Gene Clusters
Birgit C. Viertlboeck, Ramona Schmitt, Matthias A. Hanczaruk, Richard P. M. A. Crooijmans, Martien A. M. Groenen, Thomas Göbel · 2009 · The Journal of Immunology
Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study
Shahzad Ahmad, Christian A. Bannister, Sven J. van der Lee, Dina Vojinović, Hieab H.H. Adams, Alfredo Ramírez, Valentina Escott‐Price, Rebecca Sims, Emily Ann Baker, Julie H. Williams et al. · 2018 · Alzheimer s & Dementia
Plasma soluble TREM2 is associated with white matter lesions independent of amyloid and tau
Hsin-hsi C Tsai, Ya‐Fang Chen, Ruoh‐Fang Yen, Yen-Ling Lo, Kai‐Chien Yang, Jiann‐Shing Jeng, Li‐Kai Tsai, Che-Feng Chang · 2021 · Brain
Functional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2)
Konstantin Glebov, Patrick Wunderlich, Ilker Karaca, Jochen Walter · 2016 · Journal of Neuroinflammation
Plasma membrane‐focused proteomics: Dramatic changes in surface expression during the maturation of human dendritic cells
Hiroshi Watarai, Atsushi Hinohara, Jun Nagafune, Toshinori Nakayama, Masaru Taniguchi, Yasunori Yamaguchi · 2005 · PROTEOMICS
Mitochondrial DAMPs: Key mediators in neuroinflammation and neurodegenerative disease pathogenesis
Haihan Yu, Kaidi Ren, Yage Jin, Li Zhang, Hui Liu, Zhen Huang, Ziheng Zhang, Xing Chen, Yang Yang, Ziqing Wei · 2024 · Neuropharmacology
Prioritization of candidate disease genes by topological similarity between disease and protein diffusion profiles
Jie Zhu, Yufang Qin, Taigang Liu, Jun Wang, Xiaoqi Zheng · 2013 · BMC Bioinformatics
Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation
Emiko Shiba, Kumi Izawa, Ayako Kaitani, Masamichi Isobe, Akie Maehara, Koichiro Uchida, Keiko Maeda, Nobuhiro Nakano, Hideoki Ogawa, Ko Okumura et al. · 2017 · Journal of Biological Chemistry
MicroRNA-101a regulates microglial morphology and inflammation
Reiko Saika, Hiroshi Sakuma, Daisuke Noto, Shuhei Yamaguchi, Takashi Yamamura, Sachiko Miyake · 2017 · Journal of Neuroinflammation
Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER–Golgi intermediate compartment
Daniel W. Sirkis, Renan E. Aparicio, Randy W. Schekman · 2017 · Molecular Biology of the Cell
Microglia heterogeneity in health and disease
Shilauni Dadwal, Michael Thomas Heneka · 2023 · FEBS Open Bio
Immunomodulation by Transplanted Human Embryonic Stem Cell‐Derived Oligodendroglial Progenitors in Experimental Autoimmune Encephalomyelitis
Heechul Kim, Piotr Walczak, Candace L. Kerr, Chulani Galpoththawela, Assaf A. Gilad, Naser Muja, Jeff W. M. Bulte · 2012 · Stem Cells
Dynamic Changes in Serum Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) and its Gene Polymorphisms are Associated with Sepsis Prognosis
Longxiang Su, Changting Liu, Cong Li, Zhaoxu Jiang, Kun Xiao, Xin Zhang, Ming Li, Peng Yan, Dan Feng, Lixin Xie · 2012 · Inflammation
Microglia TREM2 is required for electroacupuncture to attenuate neuroinflammation in focal cerebral ischemia/reperfusion rats
Hongbei Xu, Song Mu, Wenyi Qin · 2018 · Biochemical and Biophysical Research Communications
Crosstalk among IL-23 and DNAX Activating Protein of 12 kDa–Dependent Pathways Promotes Osteoclastogenesis
Hyun-Seock Shin, Ritu Sarin, Neha Dixit, Jian Wu, Eric M. Gershwin, Edward P. Bowman, Iannis E. Adamopoulos · 2014 · The Journal of Immunology
CD300 Heterocomplexes, a New and Family-restricted Mechanism for Myeloid Cell Signaling Regulation
Águeda Martínez‐Barriocanal, Emma Comas-Casellas, Simó Schwartz, Margarita Martı́n, Joan Sayós · 2010 · Journal of Biological Chemistry