TREMs in the immune system and beyond

Dendritic cells and the control of immunity

Banchereau, J., & Steinman, R. M. (1998) · Nature · doi:10.1038/32588 · Cited by 14,486

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science · doi:10.1126/science.282.5396.2085 · Cited by 7,631

The Acute Respiratory Distress Syndrome

Matthay, M. A. (1996) · New England Journal of Medicine · doi:10.1056/nejm199605303342209 · Cited by 4,924

Toll-like receptors: critical proteins linking innate and acquired immunity

Akira, S., Takeda, K., & Kaisho, T. (2001) · Nature Immunology · doi:10.1038/90609 · Cited by 4,777

The Acute Respiratory Distress Syndrome

Ware, L. B., & Matthay, M. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421806 · Cited by 4,666

Microglia: a sensor for pathological events in the CNS

Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396

Toll-like receptors and innate immunity

Medzhitov, R. (2001) · Nature Reviews Immunology · doi:10.1038/35100529 · Cited by 4,308

Bone Resorption by Osteoclasts

Teitelbaum, S. L. (2000) · Science · doi:10.1126/science.289.5484.1504 · Cited by 3,962

HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

Wang, H., Bloom, O., Zhang, M., Vishnubhakat, J. M., Ombrellino, M., Che, J., Frazier, A., Yang, H., Ivanova, S., Borovikova, L. V., et al. (1999) · Science · doi:10.1126/science.285.5425.248 · Cited by 3,386

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA.

Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J., Lanier, L., & Spies, T. (1999) · Science · doi:10.1126/science.285.5428.727 · Cited by 3,272

Nicotinic acid modulates microglial TREM-2 gene in Phytohaemagglutinin-Induced in vitro model of Alzheimer’s disease like pathology

Amir, A., Shahid, M., Khan, S. F., Nisar, U., Faizi, S., & Sımjee, S. U. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148686 · Cited by 1

Cyclosporine A Modulates Neuroinflammation-Related Gene Expression Associated with Alzheimer’s Disease in SH-SY5Y Neuronal Cell Line: Is Cyclosporine A Beneficial/Detrimental?

Pashaei, S., Morozova‐Roche, L. A., Rahimi, Z., Mohammadi, S., Barzegari, E., Shabani, S., Salari, N., & Khodarahmi‬, R. (2025) · Biochemical Genetics · doi:10.1007/s10528-025-11210-3 · Cited by 1

Is TREM2 a Stretch: Implications of TREM2 Along Spinal Cord Circuits in Health, Aging, Injury, and Disease

Pottorf, T. S., Lane, E. L., & Álvarez, F. J. (2025) · Cells · doi:10.3390/cells14191520 · Cited by 1

Gingival crevicular fluid levels of soluble triggering receptor expressed on myeloid cells 1 in chronic periodontitis: A systematic review and meta-analysis

Kong, J., Jin, W., Wang, M., Yan, F., & Li, Y. (2025) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2025.106440 · Cited by 1

The Protective Effects of the Triggering Receptor Expressed on Myeloid Cells-1 Inhibitor LP17 on Experimental Acute Brain Injury: A Systematic Review and Meta-Analysis Based on Animal Models

Huang, L. H., Zhang, S., Wang, C., & Wang, F. (2025) · Journal of Neurotrauma · doi:10.1177/08977151251392582 · Cited by 1

TREM ‐1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights on the Role of TREM ‐1 and Syk in Monosodium Urate Crystal‐Induced Inflammation

Molad, Y., Lagovsky, I., & Kliminski, V. (2026) · Immunology · doi:10.1111/imm.70108 · Cited by 1

TREM2 as a possible link between Alzheimer's disease and diabetes mellitus

Chen, W., Huang, N., Huang, W., Wang, M., Luo, Y., & Huang, J. (2026) · Experimental Neurology · doi:10.1016/j.expneurol.2026.115739 · Cited by 3

Dietary silver nanoparticle supplementation induces Alzheimer-like lesions through Bifidobacterium deficiency-dominated gut microbiota dysbiosis and neuroinflammation

Shou, R., Wang, Z., Han, Z., Li, A., Shang, J., Lou, H., Zhang, X., Zhan, Y., Shen, G., Lu, X., et al. (2026) · npj Science of Food · doi:10.1038/s41538-026-00820-9 · Cited by 1

TREM-1-Associated Neutrophil Extracellular Trap Formation is Linked to IVIG Resistance in Kawasaki Disease: A Convergent Transcriptomic and Prospective Validation Study

Wang, S., Luo, G., Ji, Z., & Pan, S. (2026) · Journal of Clinical Immunology · doi:10.1007/s10875-026-02025-x · Cited by 1

TREM2 restrains myeloid inflammasome activation to protect against photoreceptor degeneration

wang, T., Su, L., Szczepan, M., Wang, X., Gregg, A. T., Guo, J., Smith, L. E. H., & Sun, Y. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03903-2 · Cited by 1

Glial Cells in Brain Defense Mechanisms

Noda, M. (2010) · Neuroimmune biology · doi:10.1016/s1567-7443(10)70019-3 · Cited by 1

The CNS Innate Immune System and the Emerging Roles of the Neuroimmune Regulators (NIRegs) in Response to Infection, Neoplasia and Neurodegeneration

W., J., Denizot, M., J., J., & Gasque, P. (2012) · InTech eBooks · doi:10.5772/37824 · Cited by 1

Mononuclear Phagocytes in Rheumatic Diseases

Gordon, S. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4377-1738-9.00010-4 · Cited by 1

Role of triggering receptor expressed on myeloid cells 2 in neuroinflammation and neurodegeneration of the central nervous system

Takahashi, K. (2018) · Clinical and Experimental Neuroimmunology · doi:10.1111/cen3.12479 · Cited by 1

Neurotropic murine coronavirus mediated demyelination: Factors dampening pathogenesis

Hwang, M., & Bergmann, C. C. (2024) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2024.578382 · Cited by 1

Identification of UVB-induced TREM-1–positive tolerogenic dendritic cells and TREM-1 signaling as a target in the prevention of UVB-induced immune suppression and skin carcinogenesis

Mier-Aguilar, C. A., Sherwani, M. A., Tsuruta, Y., Abdelsamad, N., Crossman, D. K., Bae, S., Slominski, A. T., Elmets, C. A., Yusuf, N., & Xu, H. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2025.10.602 · Cited by 1

NF-κB Signaling in Osteoclastogenesis

Taguchi, Y., Gohda, J., & Inoue, J. (2015) · Springer eBooks · doi:10.1007/978-4-431-55561-2_13 · Cited by 1

Microglial Biology and Physiology

Butovsky, O., Madore, C., & Weiner, H. L. (2016) · Springer eBooks · doi:10.1007/978-3-319-44022-4_13 · Cited by 1

Contribution of Neuroinflammation in the Pathogenesis of Alzheimer’s Disease

Farooqui, A. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809937-7.00006-9 · Cited by 1

Contribution of protein-derived bioactive molecules (cytokines and chemokines) in neuroinflammation, resolution, and neuroprotection

Farooqui, A. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-88460-0.00001-1 · Cited by 1

A role for altered TLR gene expression in association with increased expression of CD200R in the induction of mucosal tissue CD4+ Treg in aged mice following gavage with a liver extract along with intramuscular monophosphoryl lipid A (MPLA) injection

Khatri, I. A., Alexander, C., Brandenburg, K., Fournier, K., Lee, L., Mach, J. P., Rietschel, E., Ulmer, A. J., Waelli, T., & Gorczynski, R. M. (2008) · Experimental Gerontology · doi:10.1016/j.exger.2008.05.001 · Cited by 1

sTREM-1 as a predictor of severity and outcome in acute pancreatitis: The magic bullet or just another inflammatory mediator?*

Coimbra, R. S. M. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31817c08e0 · Cited by 1

NK Cells and Autoimmunity

Brauner, H., & Höglund, P. (2009) · Springer eBooks · doi:10.1007/978-3-642-02309-5_8 · Cited by 1

CSF sTREM2 correlates with CSF tau in advancing Parkinson’s diseasePreprint

Wilson, E. N., Swarovski, M. S., Linortner, P., Shahid, M., Zuckerman, A. J., Wang, Q., Channappa, D., Minhas, P. S., Mhatre, S. D., Plowey, E. D., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/687269 · Cited by 1

Inflammation

Steinhoff, M. S., Groves, R. W., LeBoit, P. E., & Luger, T. A. (2010) · Wiley eBooks · doi:10.1002/9781444317633.ch12 · Cited by 1

BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD MicePreprint

Lee, C. Y. D., Rocha, A. J. D. L., Inouye, K., Langfelder, P., Daggett, A., Gu, X., Jiang, L.-L., Pamonag, Z., Vaca, R., Richman, J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.03.551881 · Cited by 1

Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T cell-mediated cytotoxicityPreprint

Raza, S. A., Enose‐Akahata, Y., Blazier, A. S., Guerra, L., Beck, E., Gaitán, M. I., Ngouth, N., Drijvers, J. M., Dammer, E. B., Moodley, D., et al. (2025) · Research Square · doi:10.1101/2025.06.09.658729 · Cited by 1

Airway Macrophages: Sentinels of Health

Hussell, T., Bell, T. J., & Fujimori, T. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1311-4_8

DC-STAMP: :Localization and Function in Dendritic Cells

Eleveld-Trancikova, D. (2009) · Radboud Repository (Radboud University)

Estudo dos mecanismos genéticos e celulares durante a fase inflamatória do processo de regeneração tecidual em animais selecionados geneticamente para a máxima resposta inflamatória aguda homozigotos para os alelos R ou S do gene Slc11a1.

Gasparelo, T. A. C. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.42.2009.tde-03022010-093331

MECHANISMS BY WHICH INTERLEUKIN-4 SUPPRESSES INFLAMMATORY CYTOKINE PRODUCTION BY ACTIVATED HUMAN MONOCYTES

Woodward, E. (2011) · Murdoch University Research Portal

Estudo comparativo da ativação de macrófagos de linhagens de camundongos geneticamente selecionados para a reatividade inflamatória aguda.

de Arruda, A. G. F. (2008) · doi:10.11606/d.42.2008.tde-17112008-164429

The chicken signaling lymphocytic activation molecule (SLAM) family

Straub, C. (2014) · Elektronische Hochschulschriften der LMU München (Ludwig-Maximilians-Universität München) · doi:10.5282/edoc.16614

Dissecting the Role of Cytosolic Nucleic Acid Sensors in the Type I Interferon Response to Herpes Simplex Virus-1 and other Ligands: A Dissertation

Thompson, M. (2014) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/m20w37

- studies of DAP12-associated receptors in immune synapse formation and in responses to cytomegalovirus infection

Sjolin-Goodfellow, H. E. (2006) · Figshare

Cloning and characterization of a novel inhibitory receptor expressed by myeloid cells

Errico, D. Á. (2006) · Repositori digital de la UPF (Universitat Pompeu Fabra)

Virulence of Salmonella enterica serovar typhimurium and innate antibacterial host responses

Bjur, E. (2006) · Figshare

Genomics and immunology

Hayday, A., Giuggio, V. M., & Pennington, D. J. (2003) · Seminars in Immunology · doi:10.1016/s1044-5323(03)00045-9

Regulation of transplantation tolerance by antigen-presenting cells

Gorczynski, R. M. (2005) · Transplantation Reviews · doi:10.1016/j.trre.2005.09.001

Global transcriptional effects of PEG-IFN-α and ribavirin on peripheral blood cells obtained from patients with chronic hepatitis C

Balan, V., Aravind, L., Grill, D. E., Therneau, T. M., Sulkowski, M., Nelson, D. R., Præstgaard, J., Rosati, M. J., Birse, C. E., & Moore, P. A. (2006) · Hepatology Research · doi:10.1016/j.hepres.2006.08.007

A role of triggering receptor expressed on myeloid cells-1 expression during monosodium urate monohydrate crystal-induced acute inflammation

Murakami, Y., Akahoshi, T., & Kitasato, H. (2005) · Inflammation and Regeneration · doi:10.2492/jsir.25.160

Pathogenic mechanisms of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL)

Kiialainen, A. (2007) · STM:n Hallinnonalan avoin julkaisuarkisto (Julkari)

Implicações do polimorfismo Y402H de fator H para a concentração plasmática de proteinas do sistema complemento e do perfil lipídico em pacientes com degeneração da mácula relacionada a idade.

da Silva, A. S. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2009.tde-03022010-092312

Diabetes Pathogenesis - Role of Natural Killer Cells, T Cells and a Novel Neuropeptide

Brauner, H. (2010) · Figshare

Studies on Plasmodium falciparum asexual blood stage antigens: RAP-2/RSP-2 and Pf332 in focus

Awah, N. W. (2011) · DiVA (Stockholm University)

Functional characterization of the CD300e leukocyte receptor

Brckalo, T. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

ESTUDO DOS MECANISMOS GENÉTICOS E CELULARES DURANTE A FASE INFLAMATÓRIA DO PROCESSO DE REGENERAÇÃO TECIDUAL EM ANIMAIS SELECIONADOS GENETICAMENTE PARA A MÁXIMA RESPOSTA INFLAMATÓRIA AGUDA HOMOZIGOTOS PARA OS ALELOS R OU S DO GENE Slc11a1

Paulo, S. (2009)

On the role of treml6 in B-1a B cell development And ICOS co-stimulation in adaptive immune responses against M. tuberculosis

Nouailles, G. (2010) · DepositOnce · doi:10.14279/depositonce-2397

- studies of DAP12-associated receptors in immune synapse formation and in responses to cytomegalovirus infection

Sjolin-Goodfellow, H. E. (2006)

Amniotic Fluid-Soluble Form of Triggering Receptors Expressed on Myeloid Cells: A Physiologic Constituent at Term

Moço, N. P., Martin, L. F., Ramos, B. R. D. A., de Camargo, R. P. S., Sarmento, S. G. P., Fernandes, K. G., Filho, D. C., Miot, H. A., & da Silva, M. G. (2016) · Gynecologic and Obstetric Investigation · doi:10.1159/000446943

“Personal Training”

Tsolaki, A. (2015) · Advances in psychology, mental health, and behavioral studies (APMHBS) book series · doi:10.4018/978-1-4666-8234-4.ch002

Regulation of Toll-like Receptor Signal Transduction Pathways

Lu, Y. (2009) · TSpace (University of Toronto)

The mechanisms by which apoptotic neurons are cleared in developing dorsal root ganglia

Scheib, J. L. (2012)

Predicting the time to death following sepsis in Uganda: a biomarker-based approach

Clark, D. V. (2014)

Influência de Loci reguladores de inflamação aguda na determinação de cicatrização ou regeneração tissular em camundongos geneticamente selecionados para máxima ou mínima resposta inflamatória aguda.

Gasparelo, T. A. C. (2015) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2015.tde-10062015-140608

Identification and Characterization of the Receptor for the Soluble Fibrinogen Like Protein 2 (FGL2)

Liu, H. (2010) · TSpace (University of Toronto)

A Selected Reaction Monitoring Protocol for the Measurement of sTREM2 in Cerebrospinal Fluid

Heslegrave, A., Heywood, W., Mills, K. A., & Zetterberg, H. (2018) · Neuromethods · doi:10.1007/978-1-4939-7674-4_11

Μελέτη γενετικών πολυμορφισμών σε ασθενείς με εστιακή δυστονία

Σιώκας, Β. (2019) · doi:10.12681/eadd/45437

Genetic Aspects of Early-Onset Alzheimer’s Disease

Boggula, V. R. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821974-4.00013-3

Transcriptional Profiling of Macrophages in situ in Metastatic Melanoma Reveals Localization-Dependent Phenotypes and FunctionPreprint

Martínek, J., Lin, J., Kim, K. I., Wang, V. G., Wu, T.-C., Chiorazzi, M., Boruchov, H., Gulati, A., Seeniraj, S., Marches, F., et al. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3903548

Triggering receptor expressing on myeloid cells (TREM)-1 and acute myocardial infarction: An association vs. causality conundrum

Chalikias, G. K., & Tziakas, D. N. (2021) · International Journal of Cardiology · doi:10.1016/j.ijcard.2021.10.002

Nrf2 Regulates Microglia-Mediated Phagocytosis and Neuroinflammation Following Intracerebral HemorrhagePreprint

Liu, L., Bao, S., Yao, Z., Bai, Q., Liang, C., Zhang, J. H., Fu, P., & Wang, G. (2021) · Research Square · doi:10.21203/rs.3.rs-961639/v1

Role of Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in COVID-19 and Other Viral Pneumonias: A Systematic Review and Meta-Analysis of Clinical StudiesPreprint

de Oliveira, Y. L. M., Resende, A. D. S., de Moura, T. R., & Martins‐Filho, P. R. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4019296

Nrf2 Regulates Microglia-mediated Phagocytosis and Neuroinflammation After Intracerebral HemorrhagePreprint

Liu, L., Bao, S., Yao, Z., Bai, Q., Liang, C., Fu, P., & Wang, G. (2022) · Research Square · doi:10.21203/rs.3.rs-1373100/v1

Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.11655v0.1/reviews/1

Peer Review #2 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.1)"

(2021) · PeerJ · doi:10.7287/peerj.11655v0.1/reviews/2

Peer Review #1 of "Accuracy of triggering receptor expressed on myeloid cells 1 in diagnosis and prognosis of acute myocardial infarction: a prospective cohort study (v0.2)"

(2021) · PeerJ · doi:10.7287/peerj.11655v0.2/reviews/1

Nrf2 regulates microglia-mediated phagocytosis and neuroinflammation after intracerebral hemorrhagePreprint

Liu, L., Bao, S., Yao, Z., Bai, Q., Liang, C., Fu, P., Liu, X., Zhang, J. H., & Wang, G. (2022) · Research Square · doi:10.21203/rs.3.rs-1373100/v2

Faculty Opinions recommendation of HMGB1 regulates RANKL-induced osteoclastogenesis in a manner dependent on RAGE.

Bidwell, J. P. (2008) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1103237.559243

Mononuclear Phagocytes in Rheumatic Diseases

Gordon, S. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-3285-4.10008-7

High expression of Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) predicted poor prognosis in Glioblastoma multiformePreprint

Ma, K., Li, Y., Zhang, X., & Guo, Q. (2022) · Research Square · doi:10.21203/rs.3.rs-1655537/v1

Emerging Roles of TREM2 in Neurodegenerative Diseases

Kabir, M. T. (2022) · Springer eBooks · doi:10.1007/978-981-16-7606-2_7

WITHDRAWN: Nrf2 Regulates Microglia-Mediated Phagocytosis and Neuroinflammation after Intracerebral HemorrhagePreprint

Listed, N. A. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4181141

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer’s disease modelsPreprint

Wilson, E. N., Wang, C., Swarovski, M. S., Zera, K. A., Ennerfelt, H. E., Wang, Q., Chaney, A. M., Gauba, E., Benitez, J. A. R., Guen, Y. L., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.05.583562

A Review: Metabolism of Lipid Via TREM-2A

Otitoju, O., Iruka, A., & Danjuma, J. (2024) · Kwaghe International Journal of Sciences and Technology · doi:10.58578/kijst.v1i1.3398

Endogenous γ-Secretase Is Linked to Phagocytic Activity in Microglial Cells

Williams, E. M., Houser, M. C., Torres, S., Wieckiewicz, N., Sadek, M., Yokomizo, M., & Maesako, M. (2025) · Sensors · doi:10.3390/s25113298

Hsp70 Peptides Induce TREM-1-Dependent and TREM-1-Independent Activation of Cytotoxic Lymphocytes

Yurkina, D. M., Romanova, E. A., Чернов, А. С., Gogleva, I. S., Tvorogova, A. V., Feoktistov, A. V., Ziganshin, R., Yashin, D. V., & Sashchenko, L. P. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199750

Effects of rs2234246 with microRNA-138-5p on TREM1 mRNA expression and right hippocampal atrophy in Alzheimer’s diseasePreprint

Iga, J., Yoshino, Y., Kumon, H., Funahashi, Y., Ozaki, T., Yoshida, T., Tachibana, A., Furuta, Y., Tatewaki, Y., Taki, Y., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7694633/v1

Nasu-Hakola Disease Presenting as Rapidly Progressive Dementia With Seizures: A TREM2 Mutation Case Without Skeletal Involvement

Sarkar, Z., Alam, M. R., & Chaudhari, A. (2025) · Cureus · doi:10.7759/cureus.98664

Alzheimer’s Disease Risk Variants Interact with Amyloid-Beta to Modulate Monocyte Function

Chatila, Z. K., & Bradshaw, E. M. (2025) · Cells · doi:10.3390/cells14241990

Trem2 R47H and reduced TREM2 expression both mimic human Alzheimer’s disease signatures in micePreprint

Abel, T., Pandey, R. S., Haber, A., Garceau, D. T., Sasner, M., Kotredes, K. P., Cary, G. A., Oblak, A. L., Howell, G. R., Lamb, B. T., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.17.694758

The TREMS: A Multifaceted Family of Immunoreceptors

Gibot, S., & Lévy, B. (2005) · Springer eBooks · doi:10.1007/0-387-26272-5_33

Malarial anaemia: the potential involvement of Plasmodium falciparum rhoptry proteins

Awah, N. W. (2009) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

Additional file 1 of Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer

Wang, Q., Wu, Y., Jiang, G., & Huang, X. (2024) · Figshare · doi:10.6084/m9.figshare.26549361

Additional file 3 of Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease

Claes, C., Danhash, E., Hasselmann, J., Chadarevian, J. P., Shabestari, S. K., England, W., Lim, T. E., Hidalgo, J. L. S., Spitale, R. C., Davtyan, H., et al. (2021) · Figshare · doi:10.6084/m9.figshare.15047551

Contrôle de l'activation microgliale par les lymphocytes T dans un modèle murin de neurodégénérescence induite par la 6-OHDA

Uhlrich, J. (2014) · theses.fr (ABES) · doi:10.70675/a6a8c526zbc17z4d58za205z11fd3c99adf0

Etude génotypique et phénotypique des polymorphismes du récepteur du complément de type 1 (CR1,CD35) dans la maladie d’Alzheimer

Mahmoudi, A.-E.-R. (2015) · theses.fr (ABES) · doi:10.70675/5f05520ez1713z4991za6c8z055ab117e2bb

Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie

Vautheny, A. (2019) · theses.fr (ABES) · doi:10.70675/1812d71aze8d9z48d6z87d1z5a23a4e81953

Cellular signatures of melanocortin pathway genes across the locus coeruleus

Basak, A., Erol, F. M. B., Rosa, M. C. D., Dong, Z., Ogbolu, V. C., Glover, H. J., Rausch, R., Hargus, G., Creus‐Muncunill, J., Buchanan, H., et al. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-026-02287-x

Activation of the osmo-sensitive LRRC8 anion channel in macrophages is critical for micro-crystalline joint inflammation

Chirayath, T. W. (2023) · theses.fr (ABES) · doi:10.70675/5dbfa9f5zf8d1z4e51zaf01z277a9548aeeb

Temporal upregulation of TREM2 parallel to M2 macrophage marker expression in tuberculosis: implications for macrophage polarization regulation

Shang, X., Maimaiti, N., Tian, F., 廖春波, Sun, H., Zhou, X., Kong, W., Sun, Q., Wang, L., & Ma, X. F. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1835965

Integration of TSPO PET and fluid biomarkers to assess neuroinflammation in Parkinson’s disease

Yeh, S. H., Yu, T.-H., Liu, C.-J., Fan, S., Chen, P., Li, C., Cheng, M., & Lin, C. (2026) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-026-07971-7

Measurement of Serum Parameters Attributes the Therapeutic Effects of Music Therapy to Augmented Stress‐Coping Ability and Diminished Systemic Inflammation

Lu, Y., Yao, J., Ke-sheng, G., Wu, A., Yang, X., Wu, H., Xiao, L., & Zhang, J. (2026) · Depression and Anxiety · doi:10.1155/da/4189470

TREM1 unleashes immunosuppression in glioma: targeting macrophage polarization as a new therapeutic vulnerability

Zhang, C., Teng, D., Wang, C., Feng, R., Huang, X., Hu, B., Wang, Y., Lin, N., & Zhang, C. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1871988

Immune Regulation of Inflammation: Molecular Signaling, Resolution Mechanisms, and Therapeutic Implications

Patil, S. S., Dere, V. V., Kale, A. Y., & Otari, K. V. (2026) · Biosciences Biotechnology Research Asia · doi:10.13005/bbra/3516

The diagnostic value and pathological application of TREM2 in patients with osteoarthritis

Bao, H., Wei, W., Xu, C., Huang, Y., Zhang, W., & Ma, J. J. (2026) · Clinical Rheumatology · doi:10.1007/s10067-026-08316-3

Monocyte-Derived Macrophages Exhibit Differences in Inflammatory Gene Expression Based on Sex and Cannabis Use Pattern of the Donor: A Post-Hoc AnalysisPreprint

Avalos, B., Searson, E. G., Walter, K. C., Mastropietro, K. F., Ford, M. K., Funk, G., Spencer, M. R., Melcher, J., Shu, L., Crescini, M., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-10658020/v1

Analysis of Soluble Triggering Receptor Expressed on Myeloid Cells-1 and -2 and Fractalkine in Depression and Childhood Adversity: An Exploratory Study

Cho, A. B., Otte, C., Spitzer, C., Üsekes, B., Kuehl, L. K., Hellmann‐Regen, J., & Wingenfeld, K. (2026) · Neuropsychobiology · doi:10.1159/nps/adyag002

TREM2: A Potential Target for the Targeted Therapy of Metabolic Diseases

Li, Y., Liu, S. Q., Chu, C., & Yang, J. (2026) · Mediators of Inflammation · doi:10.1155/mi/6210178

TREM2 Attenuates Microglial Pyroptosis in Sepsis-Associated Encephalopathy Through Modulation of the mtDNA-cGAS-STING Pathway

Wang, P., Zhuang, H., Li, J., Song, X., Wu, S., He, Y., Jing, H., Qiu, X., & Lin, F. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06230-y

The biology of TREM receptors

Colonna, M. (2023) · Nature Reviews Immunology · doi:10.1038/s41577-023-00837-1 · Cited by 394

TREM and TREM-like receptors in inflammation and disease

Ford, J. W., & McVicar, D. W. (2009) · Current Opinion in Immunology · doi:10.1016/j.coi.2009.01.009 · Cited by 434

From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection

Sharif, O., & Knapp, S. (2008) · Immunobiology · doi:10.1016/j.imbio.2008.07.008 · Cited by 199

Current understanding on TREM-2 molecular biology and physiopathological functions

Bharadwaj, S., Groza, Y., Mierzwicka, J. M., & Malý, P. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112042 · Cited by 23

Cutting Edge: TREM-2 Attenuates Macrophage Activation

Turnbull, I. R., Gilfillan, S., Cella, M., Aoshi, T., Miller, M., Piccio, L., Hernandez, M., & Colonna, M. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.6.3520 · Cited by 688