TH17 cells in development: an updated view of their molecular identity and genetic programming

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

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Transforming growth factor-β induces development of the TH17 lineage

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A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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Dendritic cell interactions withHistoplasmaandParacoccidioides

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Optimal TLR9 signal converts tolerogenic CD4–8– DCs into immunogenic ones capable of stimulating antitumor immunity via activating CD4+ Th1/Th17 and NK cell responses

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MiR-9-5p and miR-106a-5p dysregulated in CD4+ T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation.

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Herpes Simplex Virus Type 1 Engages Toll Like Receptor 2 to Recruit Macrophages During Infection of Enteric Neurons

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Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-β

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Helper T cells in malignant pleural effusion

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Imbalance of T Lymphocyte Subsets in Adult Immune Thrombocytopenia

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RORγt agonist synergizes with CTLA-4 antibody to inhibit tumor growth through inhibition of Treg cells via TGF-β signaling in cancer

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Direct and Indirect Regulatory Mechanisms in TH17 cell Differentiation and Functions

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Differential IL‐10 production by DCs determines the distinct adjuvant effects of LPS and PTX in EAE induction

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Hepatitis C virus infection: A “liaison a trois” amongst the virus, the host, and chronic low-level inflammation for human survival

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In Vivo and In Vitro Studies of Th17 Response to Specific Immunotherapy in House Dust Mite-Induced Allergic Rhinitis Patients

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Cathepsin S Is Involved in Th17 Differentiation Through the Upregulation of IL-6 by Activating PAR-2 after Systemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis

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The Concept of Pathogenic TH2 Cells: Collegium Internationale Allergologicum Update 2021

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Parasites and autoimmunity: The case of fungi

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Sm-p80-based DNA vaccine made in a human use approved vector VR1020 protects against challenge infection withSchistosoma mansoniin mouse

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Elf3 Regulates Allergic Airway Inflammation by Controlling Dendritic Cell-Driven T Cell Differentiation

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Adjuvants in Fish Vaccines

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Correction: 1,25-Dihydroxyvitamin D3Inhibits the Differentiation and Migration of TH17 Cells to Protect against Experimental Autoimmune Encephalomyelitis

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Use of animal models in elucidating disease pathogenesis in IBD

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Isoforskolin Alleviates AECOPD by Improving Pulmonary Function and Attenuating Inflammation Which Involves Downregulation of Th17/IL-17A and NF-κB/NLRP3

Xiao, C., Cheng, S., Li, R., Wang, Y., Zeng, D., Jiang, H., Liang, Y., Huang, R., Pan, H., Wu, X. Y., et al. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.721273 · Cited by 25

A Systematic Review of Interleukin-17 in Oral Lichen Planus: From Etiopathogenesis to Treatment

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Imbalanced Frequencies of Th17 and Treg Cells in Acute Coronary Syndromes Are Mediated by IL-6-STAT3 Signaling

Ma, Y., Yuan, X., Deng, L., Xu, W., Zheng, Y., Yue, C., Zhang, G., Xie, F., Yang, Y. H., Gantier, M. P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0072804 · Cited by 25

Interleukin-17 contributes to cardiovascular diseases

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T cells localized to the androgen‐deprived prostate are TH1 and TH17 biased

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T-cell vaccination leads to suppression of intrapancreatic Th17 cells through Stat3-mediated RORγt inhibition in autoimmune diabetes

Wang, M., Yang, L., Sheng, X., Chen, W., Tang, H., Sheng, H., Xi, B., & Zang, Y. Q. (2011) · Cell Research · doi:10.1038/cr.2011.74 · Cited by 25

Effect of Narrow Band Ultraviolet B Therapy versus Methotrexate on Serum Levels of Interleukin-17 and Interleukin-23 in Egyptian Patients with Severe Psoriasis

Elghandour, T. M., Youssef, S. E. S., Aly, D. G., Elhameed, M. S. A., & Moneim, M. M. A. (2013) · Dermatology Research and Practice · doi:10.1155/2013/618269 · Cited by 25

Novel therapeutic targets along the Th17 pathway

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Megakaryocyte Progenitors Are the Main APCs Inducing Th17 Response to Lupus Autoantigens and Foreign Antigens

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The role of interleukin-21 in HIV infection

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Expression of Th17‐ and Treg‐specific transcription factors in vitiligo patients

Bhardwaj, S., Rani, S., Kumaran, M. S., Bhatia, A., & Parsad, D. (2020) · International Journal of Dermatology · doi:10.1111/ijd.14766 · Cited by 24

The roles of the kynurenine pathway in COVID-19 neuropathogenesis

Dehhaghi, M., Heydari, M., Panahi, H. K. S., Lewin, S. R., Heng, B., Brew, B. J., & Guillemin, G. J. (2024) · Infection · doi:10.1007/s15010-024-02293-y · Cited by 25

Maternal endotoxin exposure attenuates allergic airway disease in infant rats

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Subpopulations of helper T lymphocytes in tuberculous pleurisy

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Generation and immunologic functions of Th17 cells in malignant gliomas

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Therapeutic effects of nonerythropoietic erythropoietin analog ARA290 in experimental autoimmune encephalomyelitis rat

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Reciprocal modulation between TH17 and other helper T cell lineages

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The inflammatory milieu in idiopathic inflammatory myositis

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Nanocapsules Loaded with Iron-Saturated Bovine Lactoferrin have Antimicrobial Therapeutic Potential and Maintain Calcium, Zinc and Iron Metabolism

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Evaluation of transcription factor that regulates T helper 17 and regulatory T cells function in periodontal health and disease

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The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation

Lin, Y.-C., Lin, Y., Wu, C., Huang, M.-Y., Tsai, W., Hung, C., & Kuo, P. (2016) · Oncotarget · doi:10.18632/oncotarget.13791 · Cited by 24

Cryo-thermal therapy inducing MI macrophage polarization created CXCL10 and IL-6-rich pro-inflammatory environment for CD4+T cell-mediated anti-tumor immunity

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Withania somnifera dietary supplementation improves lipid profile, intestinal histomorphology in healthy Nile tilapia (Oreochromis niloticus), and modulates cytokines response to Streptococcus infection

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Differential induction of IL-17, IL-10, and IL-9 in human T helper cells by B7h and B7.1

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Interleukin‐12 family members and type I interferons in Th17‐mediated inflammatory disorders

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Identification of viral-mediated pathogenic mechanisms in neurodegenerative diseases using network-based approaches

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Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation

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CCAAT/Enhancer-Binding Protein α Negatively Regulates IFN-γ Expression in T Cells

Tanaka, S., Tanaka, K., Magnusson, F. C., Chung, Y., Martínez, G., Wang, Y.-H., Nurieva, R., Kurosaki, T., & Dong, C. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1303422 · Cited by 23

Emerging evidence of the molecular landscape specific for hematogenous metastasis from gastric cancer

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A review of nephrotic syndrome and atopic diseases in children

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Maternal plasma cytokines and the subsequent risk of uterine atony and postpartum hemorrhage

Gallo, D. M., Romero, R. J., Bosco, M., Chaiworapongsa, T., Gomez‐Lopez, N., Arenas‐Hernandez, M., Jung, E., Suksai, M., Gotsch, F., Erez, O., et al. (2022) · Journal of Perinatal Medicine · doi:10.1515/jpm-2022-0211 · Cited by 24

Tissue Inhibitor of Metalloproteinase 1 Is Preferentially Expressed in Th1 and Th17 T-Helper Cell Subsets and Is a Direct Stat Target Gene

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Doxycycline Attenuates Peripheral Inflammation in Rat Experimental Autoimmune Neuritis

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RAS P21 Protein Activator 3 (RASA3) Specifically Promotes Pathogenic T Helper 17 Cell Generation by Repressing T-Helper-2-Cell-Biased Programs

Wu, B., Zhang, S., Guo, Z., Wang, G., Zhang, G., Xie, L., Lou, J., Chen, X., Wu, D., Bergmeier, W., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.09.004 · Cited by 28

Regulation of T cell antitumor immune response by tumor induced metabolic stress

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Regulation of T cell differentiation and function by ubiquitin-specific proteases

Wang, A., Zhu, F., Liang, R., Li, D., & Li, B. (2019) · Cellular Immunology · doi:10.1016/j.cellimm.2019.103922 · Cited by 24

Heterogeneity of Treg/Th17 According to Cancer Progression and Modification in Biliary Tract Cancers via Self-Producing Cytokines

Kinoshita, M., Kobayashi, S., Gotoh, K., Kubo, M., Hayashi, K., Iwagami, Y., Yamada, D., Akita, H., Noda, T., Asaoka, T., et al. (2019) · Digestive Diseases and Sciences · doi:10.1007/s10620-019-06011-9 · Cited by 24

Regulation of host immune cells and cytokine production induced byTrichinella spiralisinfection

Song, Y., Xu, J., Wang, X., Yang, Y., Bai, X., Pang, J., Wang, X., Yu, M., Liu, M., Liu, X., et al. (2019) · Parasite · doi:10.1051/parasite/2019074 · Cited by 23

A new approach to the preeclampsia puzzle; MicroRNA-326 in CD4+ lymphocytes might be as a potential suspect

Zolfaghari, M. A., Motavalli, R., Soltani‐Zangbar, M. S., Parhizkar, F., Danaii, S., Maleki, L. A., Noori, M., Dolati, S., Ahmadi, M., Kafil, H. S., et al. (2021) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2021.103317 · Cited by 23

BATF regulates the development and function of IL-17 producing iNKT cells

Jordan-Williams, K. L., Poston, S., & Taparowsky, E. J. (2013) · BMC Immunology · doi:10.1186/1471-2172-14-16 · Cited by 23

Interleukin-22 participates in the inflammatory process of vitiligo

Dong, J., An, X., Zhong, H., Wang, Y., Shang, J., & Zhou, J. (2017) · Oncotarget · doi:10.18632/oncotarget.22644 · Cited by 23

Cytokine profiles affecting the pathogenesis of autoimmune hepatitis in Japanese patients

Kamijo, A., Yoshizawa, K., Joshita, S., Yoneda, S., Umemura, T., Ichijo, T., Matsumoto, A., Ôta, M., & Tanaka, E. (2011) · Hepatology Research · doi:10.1111/j.1872-034x.2011.00773.x · Cited by 22

IL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis

Lee, S.-Y., Jung, Y. O., Kim, D., Kang, C., Moon, Y., Heo, Y., Oh, H., Park, S.-J., Yang, S.-H., Kwok, S. K., et al. (2015) · The Journal of Immunology · doi:10.4049/jimmunol.1500400 · Cited by 22

β2 adrenergic agonist attenuates house dust mite-induced allergic airway inflammation through dendritic cells

Kato, G., Takahashi, K., Tashiro, H., Kurata, K., Shirai, H., Kimura, S. H., & Hayashi, S. (2014) · BMC Immunology · doi:10.1186/s12865-014-0039-y · Cited by 22

Clinical Significance of IL-23 Regulating IL-17A and/or IL-17F Positive Th17 Cells in Chronic Periodontitis

Luo, Z., Wang, H., Wu, Y., Sun, Z., & Wu, Y. (2014) · Mediators of Inflammation · doi:10.1155/2014/627959 · Cited by 23

Inhibition of interleukin‐1β‐mediated interleukin‐1 receptor‐associated kinase 4 phosphorylation by zinc leads to repression of memory T helper type 17 response in humans

Lee, H., Kim, B., Choi, Y. H., Hwang, Y., Kim, D. H., Cho, S., Hong, S. J., & Lee, W. (2015) · Immunology · doi:10.1111/imm.12536 · Cited by 22

Targeting Th17 Cells with Small Molecules and Small Interference RNA

Lin, H., Song, P., Zhao, Y., Xue, L.-J., Liu, Y., & Chu, C. (2015) · Mediators of Inflammation · doi:10.1155/2015/290657 · Cited by 22

Th17/Treg immunoregulation and implications in treatment of sulfur mustard gas-induced lung diseases

Iman, M., Rezaei, R., Jamalkandi, S. A., Shariati, P., Kheradmand, F., & Salimian, J. (2017) · Expert Review of Clinical Immunology · doi:10.1080/1744666x.2017.1389646 · Cited by 22

Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression

Chen, J., Adamiak, W., Huang, G., Atasoy, U., Rostami, A. M., & Yu, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-17371-5 · Cited by 22

Aryl Hydrocarbon Receptor in Health and Disease

Li, H., Fan, Y., Liu, J., Dong, S., Wen, B., Zhang, Y., Wang, X., Duan, X., Hu, Y., Yan, Z., et al. (2025) · MedComm · doi:10.1002/mco2.70426 · Cited by 22

Prognostic significance of interleukin 17 in cancer: a meta-analysis.

Zhang, X., Weng, W., Xu, W., Wang, Y., Yu, W., Tang, X., Ma, L., Pan, Q., Wang, J., & Sun, F. (2014) · PubMed Central · Cited by 21

Persistence of IL‐2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis

Yu, C., Oh, H., Golestaneh, N., Amadi‐Obi, A., Lee, Y. S., Eseonu, A. C., Mahdi, R. M., & Egwuagu, C. E. (2011) · European Journal of Immunology · doi:10.1002/eji.201141654 · Cited by 22

Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock

Shimura, E., Shibui, A., Narushima, S., Nambu, A., Yamaguchi, S., Akitsu, A., Leonard, W. J., Iwakura, Y., Matsumoto, K., Suto, H., et al. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.09.004 · Cited by 22

Differential Effects of Naja naja atra Venom on Immune Activity

Kou, J., Han, R., Xu, Y., Ding, X., Wang, S., Chen, C.-X., Ji, H.-Z., Ding, Z.-H., & Qin, Z. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/287631 · Cited by 21

Primary immunodeficiencies may reveal potential infectious diseases associated with immune-targeting mAb treatments

Maródi, L., & Casanova, J. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.08.009 · Cited by 21

The Clinical Relevance of IL-17-Producing CD4+CD161+ Cell and Its Subpopulations in Primary Sjögren’s Syndrome

Li, L., He, J., Zhu, L., Yang, Y., Jin, Y., Jia, R., Liu, X., Liu, Y., Sun, X., & Li, Z. (2015) · Journal of Immunology Research · doi:10.1155/2015/307453 · Cited by 21

Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis

Min, H. K., Kim, J. K., Lee, S.-Y., Kim, E., Lee, S. H., Lee, J. J., Kwok, S., Cho, M., & Park, S. (2016) · Journal of Translational Medicine · doi:10.1186/s12967-016-0942-5 · Cited by 21

Ethyl Caffeate Ameliorates Collagen-Induced Arthritis by Suppressing Th1 Immune Response

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Mechanisms of Allergic Contact Dermatitis

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