The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Role of innate and adaptive immune mechanisms in cardiac injury and repair
Open accessAbstract
Despite the advances that have been made in developing new therapeutics, cardiovascular disease remains the leading cause of worldwide mortality. Therefore, understanding the mechanisms underlying cardiovascular tissue injury and repair is of prime importance. Following cardiac tissue injury, the immune system has an important and complex role in driving both the acute inflammatory response and the regenerative response. This Review summarizes the role of the immune system in cardiovascular disease — focusing on the idea that the immune system evolved to promote tissue homeostasis following injury and/or infection, and that the inherent cost of this evolutionary development is unwanted inflammatory damage.
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Cited by
Cardioimmunology: the immune system in cardiac homeostasis and disease
Swirski, F. K., & Nahrendorf, M. (2018) · Nature Reviews Immunology · doi:10.1038/s41577-018-0065-8 · Cited by 849
The Science Underlying COVID-19: Implications for the Cardiovascular System
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Self-citationSchultheiss, H.-P., Fairweather, D., Caforio, A. L. P., Escher, F., Hershberger, R. E., Lipshultz, S. E., Liu, P. P., Matsumori, A., Mazzanti, A., McMurray, J., et al. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0084-1 · Cited by 720
Self-citationNeurohormonal activation in heart failure with reduced ejection fraction
Hartupee, J., & Mann, D. L. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.163 · Cited by 709
Self-citationDick, S. A., Wong, A., Hamidzada, H., Nejat, S., Nechanitzky, R., Vohra, S., Mueller, B., Zaman, R., Kantores, C., Aronoff, L., et al. (2022) · Science Immunology · doi:10.1126/sciimmunol.abf7777 · Cited by 538
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Metadata
- Authors
- Epelman, S., Liu, P. P., & Mann, D. L.
- Venue
- Nature Reviews Immunology
- Published
- 2015-01-23
- Volume
- 15
- Issue
- 2
- Pages
- 117-129
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W2093076255
- Cited by
- 634
- References
- 36
- FWCI
- 10.46
- Type
- journal article
- Language
- en
- Open access
- green
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