The DOI matches its Crossref record; 150 of the 150 references it cites were found in a registry or an index.
Transcriptional regulation of innate lymphoid cell fate
Open accessAbstract
Innate lymphoid cells (ILCs) are a recently described family of lymphoid effector cells that have important roles in immune defence, inflammation and tissue remodelling. It has been proposed that ILCs represent 'innate' homologues of differentiated effector T cells, and they have been categorized into three groups — namely, ILC1s, ILC2s and ILC3s — on the basis of their expression of cytokines and transcription factors that are typically associated with T helper 1 (TH1)-, TH2- and TH17-type immune responses, respectively. Indeed, remarkable similarity is seen between the specific transcription factors required for the development and diversification of different ILC groups and those that drive effector T cell differentiation. The recent identification of dedicated ILC precursors has provided a view of the mechanisms that control this first essential stage of ILC development. Here, we discuss the transcriptional mechanisms that regulate ILC development and diversification into distinct effector subsets with key roles in immunity and tissue homeostasis. We further caution against the current distinction between 'helper' versus 'killer' subsets in the evolving area of ILC nomenclature.
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1 retracted
RETRACTED: TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver
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Self-citationInnate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
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Gury-BenAri, M., Thaiss, C. A., Serafini, N., Winter, D. R., Giladi, A., Lara-Astiaso, D., Levy, M., Salame, T. M., Weiner, A., David, E., et al. (2016) · Cell · doi:10.1016/j.cell.2016.07.043 · Cited by 587
Self-citationThe Enteric Network: Interactions between the Immune and Nervous Systems of the Gut
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Flip the coin: IL-7 and IL-7R in health and disease
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Metadata
- Authors
- Serafini, N., Vosshenrich, C. A. J., & Di Santo, J. P.
- Venue
- Nature Reviews Immunology
- Published
- 2015-06-12
- Volume
- 15
- Issue
- 7
- Pages
- 415-428
- ISSN
- 1474-1733 (ISSN-L)
- 1474-1741
- OpenAlex
- W1511974199
- Cited by
- 292
- References
- 150
- FWCI
- 3.01
- Type
- journal article
- Language
- en
- Open access
- green
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