The biogenesis and emerging roles of circular RNAs

Circular RNAs are a large class of animal RNAs with regulatory potency

Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature · doi:10.1038/nature11928 · Cited by 7,990

Natural RNA circles function as efficient microRNA sponges

Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K., & Kjems, J. (2013) · Nature · doi:10.1038/nature11993 · Cited by 7,985

Circular RNAs are abundant, conserved, and associated with ALU repeats

Jeck, W. R., Sorrentino, J. A., Wang, K., Slevin, M. K., Burd, C. E., Liu, J., Marzluff, W. F., & Sharpless, N. E. (2013) · RNA · doi:10.1261/rna.035667.112 · Cited by 4,388

circRNA biogenesis competes with pre-mRNA splicing

Ashwal-Fluss, R., Meyer, M., Pamudurti, N. R., Ivanov, A., Bartok, O., Hanan, M., Evantal, N., Memczak, S., Rajewsky, N., & Kadener, S. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.08.019 · Cited by 3,083

Exon-intron circular RNAs regulate transcription in the nucleus

Li, Z., Huang, C., Bao, C., Chen, L., Lin, M., Wang, X., Zhong, G., Yu, B., Hu, W., Dai, L., et al. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2959 · Cited by 2,905

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

Rybak-Wolf, A., Stottmeister, C., Glažar, P., Jens, M., Pino, N., Giusti, S., Hanan, M., Behm, M., Bartok, O., Ashwal-Fluss, R., et al. (2015) · Molecular Cell · doi:10.1016/j.molcel.2015.03.027 · Cited by 2,423

Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures

Sanger, H. L., Klotz, G., Riesner, D., Gross, H. J., & Kleinschmidt, A. K. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.11.3852 · Cited by 2,296

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

Salzman, J., Gawad, C., Wang, P. L., Lacayo, N., & Brown, P. O. (2012) · PLoS ONE · doi:10.1371/journal.pone.0030733 · Cited by 2,239

Circular intronic long noncoding RNAs

Zhang, Y., Zhang, X.-O., Chen, T., Xiang, J.-F., Yin, Q.-F., Xing, Y.-H., Zhu, S., Yang, L., & Chen, L.-L. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.08.017 · Cited by 2,221

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

Li, Y., Zheng, Q., Bao, C., Li, S., Guo, W., Zhao, J., Chen, D., Gu, J., He, X., & Huang, S. (2015) · Cell Research · doi:10.1038/cr.2015.82 · Cited by 2,210

Regulator Non-coding RNAs: miRNA, siRNA, piRNA, lncRNA, circRNA

Altaylı, E. (2020) · Journal of Clinical Medicine of Kazakhstan · doi:10.23950/jcmk/9258 · Cited by 16

Lactate Metabolic Reprogramming Mediated by CircRNA–LDHA Complex Facilitates Innate Immune Evasion of Liver Cancer

Shen, H., Liu, B., He, J., Zhao, W., Li, W., Ma, L., Hou, L., Wáng, Y., Jin, C., Chang, Y., et al. (2025) · Advanced Science · doi:10.1002/advs.202509989 · Cited by 16

Correlation between the expressions of circular RNAs in peripheral venous blood and clinicopathological features in hepatocellular carcinoma

Wang, P., Xu, L., Zheng, X., Hu, Y.-T., Zhang, J., Ren, S., Hao, X., Li, L., Zhang, M., & Xu, M. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.02.134 · Cited by 16

The Role of Long Non-coding RNAs in Sepsis-Induced Cardiac Dysfunction

Li, J., Zhang, Y., Zhang, D., & Li, Y. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.684348 · Cited by 16

Circ_0000215 Exerts Oncogenic Function in Nasopharyngeal Carcinoma by Targeting miR-512-5p

Chen, X., Xu, W., Ma, Z., Zhu, J. L., Hu, J., Li, X., & Fu, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.688873 · Cited by 16

Circular RNA CDR1as Alleviates Cisplatin-Based Chemoresistance by Suppressing MiR-1299 in Ovarian Cancer

Wu, H., Zhao, X., Wang, J., Jiang, X., Cheng, Y., He, Y., Sun, L., & Zhang, G. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2021.815448 · Cited by 16

CircRNAs in hepatocellular carcinoma: characteristic, functions and clinical significance

Zhou, Y., Mao, X., Peng, R., & Bai, D. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.74713 · Cited by 16

Curcumin as a therapeutic agent in cancer therapy: Focusing on its modulatory effects on circular RNAs

Si, L., Zhang, L., Xing, S., Fang, P., Tian, X., Liu, X., & Xv, X. (2023) · Phytotherapy Research · doi:10.1002/ptr.7863 · Cited by 16

Novel insights regarding the role of noncoding RNAs in diabetes

Mačvanin, M., Gluvic, Z. M., Bajić, V., & Isenović, E. R. (2023) · World Journal of Diabetes · doi:10.4239/wjd.v14.i7.958 · Cited by 16

Circular RNA HIPK2 Promotes A1 Astrocyte Activation after Spinal Cord Injury through Autophagy and Endoplasmic Reticulum Stress by Modulating miR-124-3p-Mediated Smad2 Repression

Yang, J., Dong, J., Li, H., Gong, Z., Wang, B., Du, K., Zhang, C., Bi, H., Wang, J., Tian, X., et al. (2023) · ACS Omega · doi:10.1021/acsomega.3c06679 · Cited by 16

A Novel Circular RNA circITGa9 Predominantly Generated in Human Heart Disease Induces Cardiac Remodeling and Fibrosis

Li, F., Du, W. W., Li, X., Xu, J., Wu, N., Awan, F. M., Yang, Y., Alashti, F. A., Wang, S., & Yang, B. B. (2023) · Research · doi:10.34133/research.0303 · Cited by 16

CircSI-SSL: circRNA-binding site identification based on self-supervised learning

Cao, C., Wang, C.-Y., Yang, S., & Zou, Q. (2024) · Bioinform. · doi:10.1093/bioinformatics/btae004 · Cited by 14

Overcoming cancer drug-resistance calls for novel strategies targeting abnormal alternative splicing

Zhang, J., Xu, X., Deng, H., Liu, L., Xiang, Y., & Feng, J. (2024) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2024.108697 · Cited by 18

Environmental Epigenetics and Its Impacts on Disease Susceptibility: A Comprehensive Review

Ogunjobi, T. T., Gbayisomore, T. J., Nneji, P. O., Olofin, O. O., Olowe, E. N., Gigam-Ozuzu, C. D., Afolabi, J. I., Okwuokei, N. B., Boluwaji, V. A., Ojeniran, T. P., et al. (2024) · Medinformatics · doi:10.47852/bonviewmedin42022945 · Cited by 16

The Role of Non-Coding RNAs in Mitochondrial Dysfunction of Alzheimer’s Disease

Abed, S., Ebrahimi, A., Fattahi, F., Kouchakali, G., Khaniani, M. S., & Derakhshan, S. M. (2024) · Journal of Molecular Neuroscience · doi:10.1007/s12031-024-02262-y · Cited by 16

Non-Coding RNAs as Potential Diagnostic/Prognostic Markers for Hepatocellular Carcinoma

Tonon, F., Grassi, C., Tierno, D., Biasin, A., Grassi, M., Grassi, G., & Dapas, B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252212235 · Cited by 16

Differential circular RNA expression profiles of invasive and non-invasive non-functioning pituitary adenomas

Hu, Y. X., Zhang, N., Zhang, S., Zhou, P., Lv, L., Richard, S. A., Ma, W., Chen, C., Wang, X., Huang, S., et al. (2019) · Medicine · doi:10.1097/md.0000000000016148 · Cited by 16

Circular RNAs in β-cell function and type 2 diabetes-related complications: a potential diagnostic and therapeutic approach

Ghasemi, H., Sabati, Z., Ghaedi, H., Salehi, Z., & Alipoor, B. (2019) · Molecular Biology Reports · doi:10.1007/s11033-019-04937-x · Cited by 16

The Emerging Link between the Hippo Pathway and Non-coding RNA

Shimoda, M., & Moroishi, T. (2019) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b19-00795 · Cited by 16

Identification and characterization of circular RNAs in atrial appendage of patients with atrial fibrillation

Zhang, Y., Shen, H. M., Wang, P., Min, J., Yu, Y., Wang, Q., Wang, S., Wang, X., Nguyen, Q. M., Xiao, J., et al. (2020) · Experimental Cell Research · doi:10.1016/j.yexcr.2020.111821 · Cited by 16

Multifaceted regulation of translation by the epitranscriptomic modification N6-methyladenosine

Liu, X., & Zhou, J. L. (2021) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409238.2020.1869174 · Cited by 16

Circ_0008305‐mediated miR‐660/BAG5 axis contributes to hepatocellular carcinoma tumorigenesis

Yan, F., Fan, B., Wang, J., Wang, W., Tang, Q., Lu, L., Luo, Z., Pu, J., & Yang, S. (2021) · Cancer Medicine · doi:10.1002/cam4.3657 · Cited by 16

RNA sequencing reveals the expression profiles of circRNA and identifies a four-circRNA signature acts as a prognostic marker in esophageal squamous cell carcinoma

Wang, W., Zhu, D., Zhao, Z., Sun, M., Wang, F., Li, W., Zhang, J., & Jiang, G. (2021) · Cancer Cell International · doi:10.1186/s12935-021-01852-9 · Cited by 16

Identification of candidate targets for the diagnosis and treatment of atherosclerosis by bioinformatics analysis.

Gu, Y., Ma, X., Li, J., Ma, Y., & Zhang, Y. (2021) · PubMed Central · Cited by 16

Non-coding genome in small cell lung cancer between theoretical view and clinical applications

Yin, X., Yang, J., Wang, H., Luo, Y., Qin, Z., Deng, L., & Ma, X. (2022) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2022.03.024 · Cited by 16

Circ_0026218 ameliorates oxidized low-density lipoprotein-induced vascular endothelial cell dysfunction by regulating miR-188-3p/TLR4/NF-κB pathway

Liu, J., Zhang, X., Yu, Z., & Zhang, T. (2022) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-022-07416-x · Cited by 16

Circular RNAs and hereditary bone diseases

Zhai, N., Lu, Y., Wang, Y., Ren, X., & Han, J. (2018) · Intractable & Rare Diseases Research · doi:10.5582/irdr.2018.01013 · Cited by 16

Circular RNAs in Brain Physiology and Disease

Gokul, S., & Rajanikant, G. K. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-1426-1_18 · Cited by 16

Advances in mRNA vaccine therapy for breast cancer research

Li, J., Jiang, R., Wang, J., & Wang, X. (2025) · Discover Oncology · doi:10.1007/s12672-025-02542-y · Cited by 16

Star Circular RNAs In Human Cancer: Progress And Perspectives

Cheng, Y., Sun, H., Wang, H., Jiang, W., Tang, W., Chen, L., Zhang, W., Chen, Z., & Lv, C. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s215390 · Cited by 15

Circ_ 0115744 acts as miR-144 sponge to promote and predict the metastasis of colorectal cancer

Ma, X., Lv, L., & Xing, C. (2021) · Aging · doi:10.18632/aging.202513 · Cited by 15

Comprehensive Profile Analysis of Differentially Expressed circRNAs in Glucose Deprivation‐Induced Human Nucleus Pulposus Cell Degeneration

Chang, H., Wang, H., Yang, X., You, K., Jiang, M., Cai, F., Zhang, Y., Liu, L., Liu, H., & Liu, X. (2021) · BioMed Research International · doi:10.1155/2021/4770792 · Cited by 15

Circular RNAs exhibit limited evidence for translation, or translation regulation of the mRNA counterpart in terminal hematopoiesis

Nicolet, B. P., Jansen, S. B. G., Heideveld, E., Ouwehand, W. H., van den Akker, E., Lindern, M. V., & Wolkers, M. C. (2021) · RNA · doi:10.1261/rna.078754.121 · Cited by 17

Emerging roles of circular RNAs in stem cells

Wang, M., Wu, J., Wu, P., & Li, Y. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.05.015 · Cited by 15

JLCRB: A unified multi-view-based joint representation learning for CircRNA binding sites prediction

Du, X., & Xue, Z. (2022) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2022.104231 · Cited by 15

From Heterochromatin to Long Noncoding RNAs in Drosophila: Expanding the Arena of Gene Function and Regulation

Lakhotia, S. C. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-981-10-5203-3_3 · Cited by 15

Transcriptomics Analysis of Circular RNAs Differentially Expressed in Apoptotic HeLa Cells

Yaylak, B., Erdoğan, İ., & Akgül, B. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00176 · Cited by 15

Networks of mRNA Processing and Alternative Splicing Regulation in Health and Disease

Jordan, P., Gonçalves, V., Fernandes, S., Marques, T. M., Pereira, M. H. N., & Gama‐Carvalho, M. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-19966-1_1 · Cited by 16

Expression profile of circular RNA s in TMJ osteoarthritis synovial tissues and potential functions of hsa_circ_0000448 with specific back-spliced junction.

Hu, Y., Zhu, H., Bu, L., & He, D. (2019) · PubMed Central · Cited by 15

Circular RNA circEIF3I promotes papillary thyroid carcinoma progression through competitively binding to miR-149 and upregulating KIF2A expression.

Wang, Y., Li, M., Tang, Y., Jia, M., Liu, Z., & Li, H. (2020) · PubMed Central · Cited by 15

Synergistic effects of miR-708-5p and miR-708-3p accelerate the progression of osteoporosis

Wang, R., Feng, Y., Xu, H. K., Huang, H., Zhao, S., Wang, Y., Li, H., Cao, J., Xu, G., & Huang, S. (2020) · Journal of International Medical Research · doi:10.1177/0300060520978015 · Cited by 15

CircPVT1 attenuates negative regulation of NRAS by let-7 and drives cancer cells towards oncogenicity

Danac, J. M. C., & Garcia, R. L. (2021) · Scientific Reports · doi:10.1038/s41598-021-88539-3 · Cited by 15

circSLC6A6 Sponges miR-497-5p to Promote Endometrial Cancer Progression via the PI4KB/Hedgehog Axis

Hu, J., Peng, X., Du, W., Huang, Y., Zhang, C., & Zhang, X. (2021) · Journal of Immunology Research · doi:10.1155/2021/5512391 · Cited by 15

Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in oral squamous cell carcinoma

Li, Y., Gong, L., Qin, N., Wei, X., Miao, L., Yuan, H., Wang, C., & Ma, H. (2021) · Oral Oncology · doi:10.1016/j.oraloncology.2021.105437 · Cited by 15

Circ_0027089 regulates NACC1 by targeting miR-136-5p to aggravate the development of hepatitis B virus-related hepatocellular carcinoma

He, W., Zhu, X., Tang, X., Xiang, X., Yu, J., & Sun, H. (2021) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000001211 · Cited by 15

Understanding Competitive Endogenous RNA Network Mechanism in Type 1 Diabetes Mellitus Using Computational and Bioinformatics Approaches

Yi, X., & Xu, C. (2021) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s315488 · Cited by 15

Hsa_circ_0031608: A Potential Modulator of VSMC Phenotype in the Rupture of Intracranial Aneurysms

Wang, C., Luo, Y., Tang, H., Yan, Y., Chang, X., Zhao, R., Li, Q., Yang, P., Hong, B., Xu, Y., et al. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.842865 · Cited by 15

Triptolide attenuates inhibition of ankylosing spondylitis-derived mesenchymal stem cells on the osteoclastogenesis through modulating exosomal transfer of circ-0110634

Ji, W., Lu, Y., Ma, Z., Ke, G., Liu, Y., Cheng, Y., Xu, J., Liu, S., Guo, Y., Han, S., et al. (2022) · Journal of Orthopaedic Translation · doi:10.1016/j.jot.2022.05.007 · Cited by 15

Hsa_circ_0000851 promotes PDK1/p-AKT-mediated cell proliferation and migration by regulating miR-1183 in triple-negative breast cancer

Ji, C., Zhu, L., & Fang, L. (2022) · Cellular Signalling · doi:10.1016/j.cellsig.2022.110494 · Cited by 15

Circ-ABCC4 contributes to prostate cancer progression and radioresistance by mediating miR-1253/SOX4 cascade

Yu, T., Du, H., & Sun, C. (2022) · Anti-Cancer Drugs · doi:10.1097/cad.0000000000001361 · Cited by 15

Are Circular RNAs New Kids on the Block?

Lee, S., Kong, H. G., & Ryu, C. (2017) · Trends in Plant Science · doi:10.1016/j.tplants.2017.03.007 · Cited by 15

Circular RNA: From non-coding regulators to functional protein encoders

Zhang, X., Wu, H., Hong, X., Xiao, Y., & Zeng, X. (2025) · Pharmaceutical Science Advances · doi:10.1016/j.pscia.2025.100085 · Cited by 14

Circular RNA circDOCK1 contributes to osteosarcoma progression by acting as a ceRNA for miR-936 to regulate LEF1

Xu, G., Zhang, H., Shi, Y., & Yang, F. (2022) · Journal of bone oncology · doi:10.1016/j.jbo.2022.100453 · Cited by 14

Identification of human placenta-derived circular RNAs and autophagy related circRNA-miRNA-mRNA regulatory network in gestational diabetes mellitus

Bao, Y., Zhang, J., Liu, Y., Wu, L., & Yang, H. J. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.1050906 · Cited by 14

CircSCUBE3 Reduces the Anti-gastric Cancer Activity of Anti-PD-L1

Shan, H.-S., Zhang, X., Zhang, X., Wei, Y., Meng, L., Li, J., Zhang, Z., Ma, L., & Xiao, Y. (2023) · Molecular Biotechnology · doi:10.1007/s12033-023-00696-0 · Cited by 14

Exosomal non-coding RNAs in colorectal cancer metastasis

Yu, X., Bu, C., Yang, X., Jiang, W., He, X., Sun, R., Guo, H., Li, S., & Ou, C. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.117849 · Cited by 14

Epigenetic regulation of hepatocellular carcinoma progression: MicroRNAs as therapeutic, diagnostic and prognostic factors

Hashemi, M., Daneii, P., Asadalizadeh, M., Tabari, K., Matinahmadi, A., Bidoki, S. S., Motlagh, Y. S. M., Jafari, A. M., Ghorbani, A., Dehghanpour, A., et al. (2024) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2024.106566 · Cited by 14

circVAPA-rich small extracellular vesicles derived from gastric cancer promote neural invasion by inhibiting SLIT2 expression in neuronal cells

Xia, Y., Jiang, T., Li, Y., Gu, C., Lv, J., Chen, L., Xu, P., Fang, L., Chen, Z., Liu, H., et al. (2024) · Cancer Letters · doi:10.1016/j.canlet.2024.216926 · Cited by 14

Non-coding RNAs in acute ischemic stroke: from brain to periphery

Li, S., Xu, Z., Zhang, S., Sun, H., Qin, X., Zhu, L. D., Jiang, T., Zhou, J., Yan, F., & Deng, Q. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01292 · Cited by 15

Circular RNAs as a novel class of potential therapeutic and diagnostic biomarkers in reproductive biology/diseases

Song, W., Chen, X., Haiying, W., & Rahimian, N. (2024) · European journal of medical research · doi:10.1186/s40001-024-02230-7 · Cited by 14

Tear fluid derived extracellular vesicles for new biomarker discovery

Phan, N., Li, Y., Yang, M., & Liu, F. (2025) · The Ocular Surface · doi:10.1016/j.jtos.2025.05.001 · Cited by 15

circRNA expression analysis in lung adenocarcinoma: comparison of paired fresh frozen and formalin-fixed paraffin-embedded specimens

Zhang, F., Zhao, X., Dong, H., & Xu, J. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.04.145 · Cited by 14

Cross-Talk Between circRNAs and mRNAs Modulates MiRNA-mediated Circuits and Affects Melanoma Plasticity

Fumagalli, M. R., Lionetti, M. C., Zapperi, S., & Porta, C. A. M. L. (2019) · Cancer Microenvironment · doi:10.1007/s12307-019-00230-4 · Cited by 14

Comprehensive analysis of the regulatory network of differentially expressed mRNAs, lncRNAs and circRNAs in gastric cancer

Zhang, Y., Han, T., Li, J., Cai, H., Xu, J., Chen, L., & Zhan, X. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2019.109686 · Cited by 14

circVAR database: genome-wide archive of genetic variants for human circular RNAs

Zhao, M., & Qu, H. (2020) · BMC Genomics · doi:10.1186/s12864-020-07172-y · Cited by 14

CircSmg5 stimulates the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting the miR ‐194‐5p/Fzd6 axis and beta‐catenin signaling

Lü, Y., Liu, Y. K., Wan, F., Shi, S., & Tao, R. (2021) · Environmental Toxicology · doi:10.1002/tox.23425 · Cited by 14

Hsa_circ_0008259 modulates miR-21-5p and PDCD4 expression to restrain osteosarcoma progression

Guan, K., Liu, S., Duan, K., Zhang, X., Liu, H., Xu, B., Wang, X., & Jin, X. (2021) · Aging · doi:10.18632/aging.203769 · Cited by 14

CircCDK17 knockdown inhibits tumor progression and cell glycolysis by downregulaing YWHAZ expression through sponging miR-1294 in cervical cancer

Chen, R., Liang, F., Yan, J., & Wang, Y. (2022) · Journal of Ovarian Research · doi:10.1186/s13048-022-00952-y · Cited by 14

Whole transcriptome analysis of platelet concentrates during storage.

Heililahong, H., Jin, P., Lei, H., Gu, H., Qian, B., Wang, X., Dai, J., & Cai, X. (2023) · Blood transfusion · doi:10.2450/2022.0291-21 · Cited by 14

Interplay between circular RNA, microRNA, and human diseases

Kour, B., Gupta, S., Singh, R., Sophiarani, Y., & Paul, P. (2022) · Molecular Genetics and Genomics · doi:10.1007/s00438-022-01856-8 · Cited by 14

Biallelic and gene-wide genomic substitution for endogenous intron and retroelement mutagenesis in human cells

Ohno, T., Akase, T., Kono, S., Kurasawa, H., Takashima, T., Kaneko, S., & Aizawa, Y. (2022) · Nature Communications · doi:10.1038/s41467-022-31982-1 · Cited by 14

circANKRD28 inhibits cisplatin resistance in non‐small‐cell lung cancer through the miR‐221‐3p/SOCS3 axis

Song, S., Shi, Y., Zeng, D., Xu, J., Yang, Y., Guo, W., Ye, Z., & Tang, H. (2023) · The Journal of Gene Medicine · doi:10.1002/jgm.3478 · Cited by 14

Circular RNA EPHA3 suppresses progression and metastasis in prostate cancer through the miR-513a-3p/BMP2 axis

Feng, H., Deng, Z., Peng, W., Wei, X., Liu, J., & Wang, T. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04132-4 · Cited by 14

Differential Expression of miRNAs, lncRNAs, and circRNAs between Ovaries and Testes in Common Carp (Cyprinus carpio)

Hou, M., Wang, Q., Zhang, J., Zhao, R., Cao, Y., Yu, S., Wang, K., Chen, Y., Ma, Z., Sun, X., et al. (2023) · Cells · doi:10.3390/cells12222631 · Cited by 14

Overexpression of circRNA-001175 promotes proliferation and angiogenesis and inhibits apoptosis of the human umbilical vein endothelial cells (HUVECs) induced by high glucose.

Pei, X., Ye, S., Jin, G., & Yu, Y. (2018) · PubMed Central · Cited by 14

Correlation between serum circRNA and thyroid micropapillary carcinoma with cervical lymph node metastasis

Yang, W., Bai, C., Zhang, L., Li, Z., Tian, Y., Yang, Z., Wang, L., & Wu, W. (2020) · Medicine · doi:10.1097/md.0000000000023255 · Cited by 14

The 23S Ribosomal RNA From Pyrococcus furiosus Is Circularly Permuted

Birkedal, U., Beckert, B., Wilson, D. N., & Nielsen, H. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.582022 · Cited by 14

The Roles of circMTO1 in Cancer

Liu, W., Xiong, Y., Wan, R., Shan, R., Li, J., & Wen, W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.656258 · Cited by 14

Circ_0004913 sponges miR-1290 and regulates FOXC1 to inhibit the proliferation of hepatocellular carcinoma

Yu, Y., Han, S., Li, M., Song, Y., & Qi, F. (2020) · Cancer Cell International · doi:10.1186/s12935-020-01521-3 · Cited by 13

Genome-wide circular RNA (circRNA) and mRNA profiling identify a circMET-miR-410-3p regulatory motif for cell growth in colorectal cancer

Liu, Y., Chen, L., Liu, T., Su, X., Peng, L., Chen, J., Tan, F., Xing, P., Wang, Z., Di, J., et al. (2021) · Genomics · doi:10.1016/j.ygeno.2021.11.038 · Cited by 13

Circular RNAs in Diabetic Nephropathy: Updates and Perspectives

Liu, M., & Zhao, J. (2022) · Aging and Disease · doi:10.14336/ad.2022.0203 · Cited by 13

Molecular mechanism of circRNAs in drug resistance in renal cell carcinoma

Qin, S., Wang, Y., Wang, P., & Lv, Q. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02790-w · Cited by 13

Novel circRNA-miRNA-mRNA networks regulated by maternal exercise in fetal hearts of pregestational diabetes

Ye, F., Lu, X., van Neck, R., Jones, D. L., & Feng, Q. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.121308 · Cited by 13

Molecular and Therapeutic Roles of Non-Coding RNAs in Oral Cancer—A Review

Umapathy, V. R., Natarajan, P. M., & Swamikannu, B. (2024) · Molecules · doi:10.3390/molecules29102402 · Cited by 13

Insights into the regulatory role of epigenetics in moyamoya disease: Current advances and future prospectives

Xu, S., Chen, T., Yu, J., Wan, L., Zhang, J., Chen, J., Wei, W., & Li, X. (2024) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2024.102281 · Cited by 13

Autophagy-related lncRNAs and exosomal lncRNAs in colorectal cancer: focusing on lncRNA-targeted strategies

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