Transcriptional control of human p53-regulated genes

p53, the cellular gatekeeper for growth and division

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Surfing the p53 network

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Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain

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Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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Maximum Entropy Modeling of Short Sequence Motifs with Applications to RNA Splicing Signals

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Drosophila p53 controls Notch expression and balances apoptosis and proliferation

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Negative regulation of p53 by Ras superfamily protein RBEL1A

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p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis

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Self-aggregation and coaggregation of the p53 core fragment with its aggregation gatekeeper variant

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Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process

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Apoptotic mechanism behind the testicular atrophy in photorefractory and scotosensitive quail: Involvement of GnIH induced p-53 dependent Bax-Caspase-3 mediated pathway

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Functional Analysis of Differentially Expressed Acetylated Spermatozoal Proteins in Infertile Men with Unilateral and Bilateral Varicocele

Selvam, M. K. P., Samanta, L., & Agarwal, A. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21093155 · Cited by 27

Transgelin induces apoptosis of human prostate LNCaP cells through its interaction with p53

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Autophagy induction by low-dose cisplatin: The role of p53 in autophagy

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Polychlorinated biphenyl quinone induces oxidative DNA damage and repair responses: The activations of NHEJ, BER and NER via ATM-p53 signaling axis

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MdmX Is Required for p53 Interaction with and Full Induction of the Mdm2 Promoter after Cellular Stress

Biderman, L., Poyurovsky, M. V., Assia, Y., Manley, J. L., & Prives, C. L. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.06150-11 · Cited by 27

TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1) stable silencing increases late apoptosis by upregulation of caspase 9 and APAF1 in RPMI8226 multiple myeloma cell line

Alves, V. L. F., de Oliveira, M. B., Zanatta, D. B., Strauss, B. E., & Colleoni, G. W. B. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.03.011 · Cited by 25

Regenerative repair of Pifithrin-α in cerebral ischemia via VEGF dependent manner

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Low-Dose Methylmercury-Induced Genes Regulate Mitochondrial Biogenesis via miR-25 in Immortalized Human Embryonic Neural Progenitor Cells

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Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response

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Multifunctional Compounds for Activation of the p53‐Y220C Mutant in Cancer

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Prognostic Effect of Long Noncoding RNA NEAT1 Expression Depends on p53 Mutation Status in Cancer

Idogawa, M., Nakase, H., Sasaki, Y., & Tokino, T. (2019) · Journal of Oncology · doi:10.1155/2019/4368068 · Cited by 27

NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

Haider, N., Dutt, P., van de Kooij, B., Ho, J., Palomero, L., Pujana, M. Á., Yaffe, M. B., & Stambolic, V. (2020) · Oncogene · doi:10.1038/s41388-020-1361-x · Cited by 26

The guardian's choice: how p53 enables context‐specific decision‐making in individual cells

Friedel, L., & Loewer, A. (2021) · FEBS Journal · doi:10.1111/febs.15767 · Cited by 27

The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney

Higgins, C. E., Tang, J., Higgins, S. P., Gifford, C. C., Mian, B. M., Jones, D., Zhang, W., Costello, A., Conti, D. J., Samarakoon, R., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.678524 · Cited by 25

Alternative polyadenylation determines the functional landscape of inverted Alu repeats

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Infliximab restores the balance between pro- and anti-apoptotic proteins in regressing psoriatic lesions

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The Coordinated P53 and Estrogen Receptor Cis-Regulation at an FLT1 Promoter SNP Is Specific to Genotoxic Stress and Estrogenic Compound

Ciribilli, Y., Andreotti, V., Menéndez, D., Langen, J.-S., Schönfelder, G., Resnick, M. A., & Inga, A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010236 · Cited by 26

Biosemiotic Entropy of the Genome: Mutations and Epigenetic Imbalances Resulting in Cancer

Gryder, B. E., Nelson, C. W., & Shepard, S. S. (2013) · Entropy · doi:10.3390/e15010234 · Cited by 27

Molecular imaging of p53 signal pathway in lung cancer cell cycle arrest induced by cisplatin

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Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor

Adikesavan, A. K., Karmakar, S., Pardo, P. S., Wang, L., Liu, S., Li, W., & Smith, C. S. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.01216-13 · Cited by 26

p53-Dependent repression of focal adhesion kinase in response to estradiol in breast cancer cell-lines

Anaganti, S., Fernandez‐Cuesta, L., Langerød, A., Hainaut, P. L., & Olivier, M. (2010) · Cancer Letters · doi:10.1016/j.canlet.2010.10.008 · Cited by 26

Alterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 Mutants

Giorgi, C., Bonora, M., Missiroli, S., Morganti, C., Morciano, G., Wieckowski, M. R., & Pinton, P. (2016) · Frontiers in Oncology · doi:10.3389/fonc.2016.00042 · Cited by 26

Wasabi 6‐(methylsulfinyl)hexyl isothiocyanate induces apoptosis in human colorectal cancer cells through p53‐independent mitochondrial dysfunction pathway

Yano, S., Wu, S., Sakao, K., & Hou, D. (2018) · BioFactors · doi:10.1002/biof.1431 · Cited by 26

DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites

Yan, Q., Ding, J., Khan, S. J., Lawton, L. N., & Shipp, M. A. (2023) · iScience · doi:10.1016/j.isci.2023.106444 · Cited by 25

Tumor Suppressor RASSF1A Promoter: p53 Binding and Methylation

Tian, Y., Hou, Y., Zhou, X., Cheng, H., & Zhou, R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017017 · Cited by 25

Conformations of p53 response elements in solution deduced using site-directed spin labeling and Monte Carlo sampling

Zhang, X., Machado, A. C. D., Ding, Y. C., Chen, Y., Lü, Y., Duan, Y., Tham, K. W., Chen, L., Rohs, R., & Qin, P. Z. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1219 · Cited by 25

Discovery of novel polycyclic spiro-fused carbocyclicoxindole-based anticancer agents

Zhang, L., Ren, W. T., Wang, X., Zhang, J., Liu, J., Zhao, L., & Zhang, X. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.12.021 · Cited by 25

Heterogeneous nuclear ribonucleoprotein (hnRNP) L promotes DNA damage-induced cell apoptosis by enhancing the translation of p53

Seo, J., Kim, D., Kim, S., Kim, H.-J., Ryu, H. G., Lee, J., Lee, K., & Kim, K. (2017) · Oncotarget · doi:10.18632/oncotarget.17003 · Cited by 27

TSPAN 31 is a critical regulator on transduction of survival and apoptotic signals in hepatocellular carcinoma cells

Wang, J., Zhou, Y., Li, D., Sun, X., Deng, Y., & Zhao, Q. (2017) · FEBS Letters · doi:10.1002/1873-3468.12737 · Cited by 25

Peptide Hormone Regulation of DNA Damage Responses

Chesnokova, V., & Melmed, S. K. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa009 · Cited by 27

The complex architecture of p53 binding sites

Senitzki, A., Safieh, J., Sharma, V., Golovenko, D., Danin‐Poleg, Y., Inga, A., & Haran, T. E. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa1283 · Cited by 25

Entosis is induced by ultraviolet radiation

Chen, R., Ram, A. R., Albeck, J. G., & Overholtzer, M. (2021) · iScience · doi:10.1016/j.isci.2021.102902 · Cited by 26

Current Prognostic and Predictive Biomarkers for Endometrial Cancer in Clinical Practice: Recommendations/Proposal from the Italian Study Group

Zannoni, G. F., Bragantini, E., Castiglione, F., Fassan, M., Troncone, G., Inzani, F. S., Pesci, A., Santoro, A., & Fraggetta, F. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.805613 · Cited by 25

Road to the crossroads of life and death: Linking sister chromatid cohesion and separation to aneuploidy, apoptosis and cancer

Panigrahi, A. K., & Pati, D. (2009) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2008.12.002 · Cited by 26

Phospho-ΔNp63α/SREBF1 protein interactions: Bridging cell metabolism and cisplatin chemoresistance

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Waking up the sleepers: shared transcriptional pathways in axonal regeneration and neurogenesis

Quadrato, G., & Giovanni, S. D. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1099-x · Cited by 25

Expression of p53 in the Effects of Artesunate on Induction of Apoptosis and Inhibition of Proliferation in Rat Primary Hepatic Stellate Cells

Longxi, P., Bu-wu, F., Yuan, W., & Gao, S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026500 · Cited by 25

Crystal Structures of the DNA-binding Domain Tetramer of the p53 Tumor Suppressor Family Member p73 Bound to Different Full-site Response Elements

Ethayathulla, A. S., Nguyen, H. T., & Viadiu, H. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.408039 · Cited by 25

The Presence of p53 Influences the Expression of Multiple Human Cytomegalovirus Genes at Early Times Postinfection

Hannemann, H., Rosenke, K., O’Dowd, J. M., & Fortunato, E. A. (2009) · Journal of Virology · doi:10.1128/jvi.02075-08 · Cited by 25

Ku80 Deletion Suppresses Spontaneous Tumors and Induces a p53-Mediated DNA Damage Response

Holcomb, V. B., Rodier, F., Choi, Y., Busuttil, R. A., Vogel, H. S., Vijg, J., Campisi, J., & Hasty, P. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-2085 · Cited by 25

uc.338 targets p21 and cyclin D1 via PI3K/AKT pathway activation to promote cell proliferation in colorectal cancer

Zhang, Y., Wang, S., Qian, W., Ji, D., Wang, Q., Zhang, Z., Wang, S., Ji, B., Fu, Z., & Sun, Y. (2018) · Oncology Reports · doi:10.3892/or.2018.6480 · Cited by 25

Age-related p53 SUMOylation accelerates senescence and tau pathology in Alzheimer’s disease

Wan, L., Yang, F., Yin, A., Luo, Y., Yi, L. I. U., Liu, F., Wang, J., Liu, R., & Wang, X. (2025) · Cell Death and Differentiation · doi:10.1038/s41418-025-01448-0 · Cited by 26

The Energy Costs of Insulators in Biochemical Networks

Barton, J. P., & Sontag, E. D. (2013) · Biophysical Journal · doi:10.1016/j.bpj.2013.01.056 · Cited by 26

Context is key: Understanding the regulation, functional control, and activities of the p53 tumour suppressor

Moxley, A. H., & Reisman, D. (2020) · Cell Biochemistry and Function · doi:10.1002/cbf.3590 · Cited by 25

Angiogenic factor AGGF1 acts as a tumor suppressor by modulating p53 post-transcriptional modifications and stability via MDM2

Si, W., Zhou, B., Xie, W. F., Li, H., Li, K., Li, S., Deng, W., Shi, P., Yuan, C., Ke, T., et al. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.10.014 · Cited by 26

The Common Germline TP53-R337H Mutation Is Hypomorphic and Confers Incomplete Penetrance and Late Tumor Onset in a Mouse Model

Jeffers, J. R., Pinto, E. M., Rehg, J. E., Clay, M. R., Wang, J., Neale, G. A. M., Heath, R. J., Lozano, G., Lalli, E., de Figueiredo, B. C., et al. (2021) · Cancer Research · doi:10.1158/0008-5472.can-20-1750 · Cited by 22

Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

Butturini, E., Butera, G., Pacchiana, R., de Prati, A. C., Mariotto, S., & Donadelli, M. (2021) · Cells · doi:10.3390/cells10113149 · Cited by 25

Transcriptional Dynamics of DNA Damage Responsive Genes in Circulating Leukocytes during Radiotherapy

Cruz-Garcia, L., Nasser, F., O’Brien, G., Grepl, J., Vinnikov, V. A., Starenkiy, V., Artiukh, S. V., Gramatiuk, S. M., & Badie, C. (2022) · Cancers · doi:10.3390/cancers14112649 · Cited by 27

Expression of Apoptosis-Related Biomarkers in Inflamed Nasal Sinus Epithelium of Patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP)—Evaluation at mRNA and miRNA Levels

Morawska–Kochman, M., Śmieszek, A., Marcinkowska, K. A., Marycz, K., Nelke, K., Zub, K., Zatoński, T., & Bochnia, M. (2022) · Biomedicines · doi:10.3390/biomedicines10061400 · Cited by 28

Dynamic regulation of cancer stem cells and clinical challenges

Ni, C., & Huang, J. (2012) · Clinical & Translational Oncology · doi:10.1007/s12094-012-0927-7 · Cited by 24

Sensitive single‐molecule protein quantification and protein complex detection in a microarray format

Tessler, L. A., & Mitra, R. D. (2011) · PROTEOMICS · doi:10.1002/pmic.201100361 · Cited by 24

Specific and effective gene knock-down in early chick embryos using morpholinos but not pRFPRNAi vectors

Mende, M., Christophorou, N., & Streit, A. (2008) · Mechanisms of Development · doi:10.1016/j.mod.2008.08.005 · Cited by 24

Role of Rho-Kinase Gene Polymorphisms and Protein Expressions in Colorectal Cancer Development

Sarı, İ., Berberoğlu, B., Özkara, E., Öztuzcu, S., Camcı, C., & Demiryürek, A. T. (2013) · Pathobiology · doi:10.1159/000341395 · Cited by 24

Nutlin-3a Efficacy in Sarcoma Predicted by Transcriptomic and Epigenetic Profiling

Pishas, K. I., Neuhaus, S. J., Clayer, M., SCHREIBER, A. W., Lawrence, D., Perugini, M., Whitfield, R. J., Farshid, G., Manavis, J., Chryssidis, S., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-13-2424 · Cited by 24

Loss of p53-inducible long non-coding RNA LINC01021 increases chemosensitivity

Kaller, M., Götz, U., & Hermeking, H. (2017) · Oncotarget · doi:10.18632/oncotarget.22245 · Cited by 24

Survivin expression modulates the sensitivity of A549 lung cancer cells resistance to vincristine

Zhou, C., Zhu, Y., Lu, B., Zhao, W., & Zhao, X. (2018) · Oncology Letters · doi:10.3892/ol.2018.9277 · Cited by 24

A Well-Controlled BioID Design for Endogenous Bait Proteins

Vandemoortele, G., Sutter, D. D., Moliere, A., Pauwels, J., Gevaert, K., & Eyckerman, S. (2018) · Journal of Proteome Research · doi:10.1021/acs.jproteome.8b00367 · Cited by 22

p53, stem cell biology and childhood blastomas

Oh, L., Hafsi, H., Hainaut, P. L., & Ariffin, H. (2019) · Current Opinion in Oncology · doi:10.1097/cco.0000000000000504 · Cited by 23

TP53 Polymorphisms in Sporadic North Indian Breast Cancer Patients

Sharma, S., Sambyal, V., Guleria, K., Manjari, M., Sudan, M., Uppal, M. S., Singh, N. R., Bansal, D., & Gupta, A. K. (2014) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2014.15.16.6871 · Cited by 23

Calliandra portoricensis ameliorates ovarian and uterine oxido-inflammatory responses in N -methyl- N -nitrosourea and benzo[a]pyrene-treated rats

Adefisan, A. O., Madu, J. C., Owumi, S. E., & Adaramoye, O. A. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220947387 · Cited by 23

p53 alters intracellular Ca2+ signaling through regulation of TRPM4

Kappel, S., Ross‐Kaschitza, D., Hauert, B., Rother, K., & Peinelt, C. (2022) · Cell Calcium · doi:10.1016/j.ceca.2022.102591 · Cited by 23

CDC20: a novel therapeutic target in cancer.

He, W., & Meng, J. (2023) · PubMed Central · Cited by 23

Cell Context Dependent p53 Genome-Wide Binding Patterns and Enrichment at Repeats

Botcheva, K., & McCorkle, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113492 · Cited by 23

Induction and activation of the p53 pathway: a role for the protein kinase CK2?

Meek, D. W., & Cox, M. L. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-0966-3 · Cited by 26

Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis

Chander, H., Brien, C. D., Truesdell, P. F., Watt, K., Meens, J., Schick, C., Germain, D., & Craig, A. W. (2014) · Breast Cancer Research · doi:10.1186/s13058-014-0503-x · Cited by 23

Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation

Malčíková, J., Tichý, B., Damborský, J., Kabáthová, J., Trbušek, M., Mayer, J., & Pospı́šilová, Š. (2010) · Biological Chemistry · doi:10.1515/bc.2010.027 · Cited by 23

NIR, an inhibitor of histone acetyltransferases, regulates transcription factor TAp63 and is controlled by the cell cycle

Heyne, K., Willnecker, V., Schneider, J., Conrad, M., Raulf, N., Schüle, R., & Roemer, K. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq016 · Cited by 23

Molecular Regulation of Cellular Senescence by MicroRNAs: Implications in Cancer and Age-Related Diseases

Neault, M., Couteau, F., Bonneau, É., Guire, V. D., & Mallette, F. A. (2017) · International review of cytology · doi:10.1016/bs.ircmb.2017.04.001 · Cited by 23

Delay in development and behavioural abnormalities in the absence of p53 in zebrafish

Elabd, S., Jabeen, N. A., Gerber, V., Peravali, R., Bourdon, J., Kancherla, S., Vallone, D., & Blattner, C. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220069 · Cited by 20

Crosstalk Between Vitamin D and p53 Signaling in Cancer: An Update

Reichrath, J., Reichrath, S., VOGT, T. M., & Römer, K. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-46227-7_15 · Cited by 23

Protective effect of hesperidin against N,N′‐dimethylhydrazine induced oxidative stress, inflammation, and apoptotic response in the colon of Wistar rats

Afzal, S. M., Vafa, A., Rashid, S., Barnwal, P., Shahid, A., Shree, A., Islam, J., Ali, N., & Sultana, S. (2020) · Environmental Toxicology · doi:10.1002/tox.23068 · Cited by 23

Non-Small Cell Lung Cancer Harboring Concurrent EGFR Genomic Alterations: A Systematic Review and Critical Appraisal of the Double Dilemma

Gristina, V., Mantia, M. L., Galvano, A., Cutaia, S., Barraco, N., Castiglia, M., Perez, A., Bono, M., Iacono, F., Greco, M., et al. (2021) · Journal of Molecular Pathology · doi:10.3390/jmp2020016 · Cited by 24

p53 mRNA Metabolism Links with the DNA Damage Response

Gnanasundram, S. V., Bonczek, O., Wang, L., Chen, S., & Fåhræus, R. (2021) · Genes · doi:10.3390/genes12091446 · Cited by 27

EBV-positive Hodgkin lymphoma is associated with suppression of p21cip1/waf1 and a worse prognosis

Liu, T., Wu, S., Huang, M.-H., Lo, F., Tsai, M., Tsai, C.-H. A., Hsu, S.-M., & Lin, C. (2010) · Molecular Cancer · doi:10.1186/1476-4598-9-32 · Cited by 23

The can and can’t dos of p53 RNA

Candeias, M. M. (2011) · Biochimie · doi:10.1016/j.biochi.2011.06.010 · Cited by 23

Apoptosis for prediction of radiotherapy late toxicity: lymphocyte subset sensitivity and potential effect of TP53 Arg72Pro polymorphism

Fuentes-Raspall, M. J., Caragol, I., Alonso, C., y Cajal, T. R., Fisas, D., Seoane, A., Carvajal, N., Bonache, S., Dı́ez, O., & Gutiérrez‐Enríquez, S. (2014) · APOPTOSIS · doi:10.1007/s10495-014-1056-2 · Cited by 23

TP53 genetic polymorphisms, interactions with lifestyle factors and lung cancer risk: a case control study in a Chinese population

Li, Y., Chang, S., Niu, R., Liu, L., Crabtree-Ide, C. R., Zhao, B., Shi, J., Han, X., Li, J., Su, J., et al. (2013) · BMC Cancer · doi:10.1186/1471-2407-13-607 · Cited by 23

Peptide Activators of the p53 Tumor Suppressor

Zhan, C., & Lu, W. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211795222577 · Cited by 23

Recent progress and open challenges in modeling p53 dynamics in single cells

Batchelor, E., & Loewer, A. (2017) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2017.04.007 · Cited by 23

p53: from understanding its structure to advances in therapeutic targeting

Wang, W., Liu, X., Liu, H., Abolhassani, H., Yan, H., Zhang, H., & Wang, X. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02549-5 · Cited by 29

TP53 mutations in head and neck cancer cells determine the Warburg phenotypic switch creating metabolic vulnerabilities and therapeutic opportunities for stratified therapies

Wilkie, M. D., Anaam, E. A., Lau, A., Rubbi, C. P., Jones, T. M., Boyd, M. T., & Vlatković, N. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.02.032 · Cited by 23

The p53 pathway in vasculature revisited: A therapeutic target for pathological vascular remodeling?

Cui, X., Pan, G., Chen, Y., Guo, X., Liu, T., Zhang, J., Yang, X., Cheng, M., Gao, H., & Jiang, F. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105683 · Cited by 21

The Cell Cycle

Yang, V. W. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-809954-4.00008-6 · Cited by 24

Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program

Gencel‐Augusto, J., Su, X., Qi, Y., Whitley, E. M., Pant, V., Xiong, S., Shah, V. V., Lin, J., Perez, E., Fiorotto, M. L., et al. (2023) · Cancer Discovery · doi:10.1158/2159-8290.cd-22-0872 · Cited by 22

Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells

Li, H.-Y., Choi, Y. J., Hanes, M. A., Marple, T. C., Vogel, H. S., & Hasty, P. (2009) · Oncogene · doi:10.1038/onc.2009.57 · Cited by 22

Cooperativity Dominates the Genomic Organization of p53-Response Elements: A Mechanistic View

Pan, Y., & Nussinov, R. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000448 · Cited by 22

Efficient motif search in ranked lists and applications to variable gap motifs

Leibovich, L., & Zohar Yakhini, B. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks206 · Cited by 22

Basal and copper-induced expression of metallothionein isoform 1,2 and 3 genes in epithelial cancer cells: The role of tumor suppressor p53

Ostrakhovitch, E. A., Song, Y., & Cherian, M. G. (2016) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2016.01.008 · Cited by 23

p53 targets TSPAN8 to prevent invasion in melanoma cells

Agaësse, G., Barbollat‐Boutrand, L., Kharbili, M. E., Berthier‐Vergnes, O., & Masse, I. (2017) · Oncogenesis · doi:10.1038/oncsis.2017.11 · Cited by 22

Synthesis of dispirooxindoles containing N-unsubstituted heterocyclic moieties and study of their anticancer activity

Beloglazkina, A. A., Karpov, N. A., Mefedova, S., Polyakov, V. S., Skvortsov, D. A., Kalinina, M., Тафеенко, В. А., Majouga, A. G., Zyk, N. V., & Beloglazkina, E. K. (2019) · Russian Chemical Bulletin · doi:10.1007/s11172-019-2511-6 · Cited by 22

Genipin increases oxaliplatin-induced cell death through autophagy in gastric cancer

Kim, B. R., Jeong, Y. A., Kim, D. Y., Kim, J. L., Jeong, S., Na, Y. J., Yun, H. K., Park, S. H., Jo, M. J., Ashktorab, H., et al. (2019) · Journal of Cancer · doi:10.7150/jca.34773 · Cited by 24

Targeted modulation of E3 ligases using engineered ubiquitin variants

LeBlanc, N., Mallette, E., & Zhang, W. (2020) · FEBS Journal · doi:10.1111/febs.15536 · Cited by 22

Modifying effect of MDM4 variants on risk of HPV16‐associated squamous cell carcinoma of oropharynx

Yu, H., Sturgis, E. M., Liu, Z., Wang, L., Wei, Q., & Li, G. (2011) · Cancer · doi:10.1002/cncr.26423 · Cited by 22

Soluble Guanylyl Cyclase α1 and p53 Cytoplasmic Sequestration and Down-Regulation in Prostate Cancer

Cai, C., Hsieh, C.-L., Gao, S., Kannan, A., Bhansali, M., Govardhan, K., Dutta, R. N., & Shemshedini, L. (2011) · Molecular Endocrinology · doi:10.1210/me.2010-0394 · Cited by 24

Analysis Transcriptional control of human p53-regulated genes

Riley, T., Sontag, E. D., Chen, P., & Levine, A. (2008)

Transcriptional repression mediated by the p53 tumour suppressor

Ho, J., & Benchimol, S. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401191 · Cited by 203

p53 Function and Dysfunction in Human Health and Diseases

D’Orazi, G. (2023) · Biomolecules · doi:10.3390/biom13030506 · Cited by 19

The Regulation of p53 Protein Function by Phosphorylation

MacLaine, N. J., & Hupp, T. (2010) · Molecular biology intelligence unit · doi:10.1007/978-1-4419-8231-5_4 · Cited by 2

Transcriptional regulation by p53: one protein, many possibilities

Laptenko, O., & Prives, C. L. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401916 · Cited by 515