The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
The spatial and temporal organization of ubiquitin networks
Open accessAbstract
In the past decade, the diversity of signals generated by the ubiquitin system has emerged as a dominant regulator of biological processes and propagation of information in the eukaryotic cell. A wealth of information has been gained about the crucial role of spatial and temporal regulation of ubiquitin species of different lengths and linkages in the nuclear factor-κB (NF-κB) pathway, endocytic trafficking, protein degradation and DNA repair. This spatiotemporal regulation is achieved through sophisticated mechanisms of compartmentalization and sequential series of ubiquitylation events and signal decoding, which control diverse biological processes not only in the cell but also during the development of tissues and entire organisms.
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Cites
Mdm2 promotes the rapid degradation of p53
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Identification of ubiquitin ligases required for skeletal muscle atrophy.
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RING Domain E3 Ubiquitin Ligases
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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
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Regulation of autophagy by cytoplasmic p53
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Linear ubiquitination prevents inflammation and regulates immune signalling
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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
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Cited by
Allosteric post-translational modification codes
Nussinov, R., Tsai, C.-J., Xin, F., & Radivojac, P. (2012) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2012.07.001 · Cited by 211
Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection
Fiskin, E., Bionda, T., Dikic, I., & Behrends, C. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.04.015 · Cited by 114
The Design of Covalent Allosteric Drugs
Nussinov, R., & Tsai, C.-J. (2015) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010814-124401 · Cited by 112
Recognising the signals for endosomal trafficking
Weeratunga, S., Paul, B., & Collins, B. M. (2020) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2020.02.005 · Cited by 83
The ubiquitin E3 ligase NOSIP modulates protein phosphatase 2A activity in craniofacial development
Hoffmeister, M., Prelle, C., Küchler, P., Kovacevic, I., Moser, M., Müller-Esterl, W., & Oess, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0116150 · Cited by 21
Metadata
- Authors
- Grabbe, C., Husnjak, K., & Dikic, I.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2011-03-30
- Volume
- 12
- Issue
- 5
- Pages
- 295-307
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2155304845
- Cited by
- 365
- References
- 13
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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