The porin and the permeating antibiotic: a selective diffusion barrier in Gram-negative bacteria

Molecular Basis of Bacterial Outer Membrane Permeability Revisited

Nikaido, H. (2003) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.67.4.593-656.2003 · Cited by 4,316

A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics

Kohanski, M. A., Dwyer, D. J., Hayete, B., Lawrence, C. A., & Collins, J. J. (2007) · Cell · doi:10.1016/j.cell.2007.06.049 · Cited by 2,982

Multidrug-resistance efflux pumps ? not just for resistance

Piddock, L. J. V. (2006) · Nature Reviews Microbiology · doi:10.1038/nrmicro1464 · Cited by 1,523

Crystal structures explain functional properties of two E. coli porins

Cowan, S. W., Schirmer, T., Rummel, G., Steiert, M., Ghosh, R., Pauptit, R. A., Jansonius, J. N., & Rosenbusch, J. P. (1992) · Nature · doi:10.1038/358727a0 · Cited by 1,521

Structure and function of bacterial outer membrane proteins: barrels in a nutshell

Koebnik, R., Locher, K. P., & Gelder, P. V. (2000) · Molecular Microbiology · doi:10.1046/j.1365-2958.2000.01983.x · Cited by 1,206

Efflux-mediated antimicrobial resistance

Poole, K. (2005) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dki171 · Cited by 1,082

Efflux-Mediated Drug Resistance in Bacteria

Li, X.-Z., & Nikaido, H. (2004) · Drugs · doi:10.2165/00003495-200464020-00004 · Cited by 803

Lack of development of new antimicrobial drugs: a potential serious threat to public health

Norrby, S. R., Nord, C. E., & Finch, R. (2005) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(05)01283-1 · Cited by 500

The structure of bacterial outer membrane proteins

Schulz, G. E. (2002) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(02)00577-1 · Cited by 488

Outer membrane barrier as a mechanism of antimicrobial resistance

Nikaido, H. (1989) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.33.11.1831 · Cited by 464

A hydrogel-based in vitro assay for the fast prediction of antibiotic accumulation in Gram-negative bacteria

Richter, R., Kamal, M. A. M., García-Rivera, M. A., Kaspar, J., Junk, M., Elgaher, W. A. M., Srikakulam, S. K., Greß, A., Beckmann, A., Grißmer, A., et al. (2020) · Materials Today Bio · doi:10.1016/j.mtbio.2020.100084 · Cited by 14

Modern vaccine development via reverse vaccinology to combat antimicrobial resistance

Tobuse, A. J., Wei, A. C., & Yeong, K. Y. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120660 · Cited by 16

Synergistic Antibacterial Effect and Mechanism of Allicin and an Enterobacter cloacae Bacteriophage

Tao, Z., Geng, D., Tao, J., Wang, J., Liu, S., Wang, Q., Xu, F. F., Xiao, S., & Wang, R. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.03155-22 · Cited by 14

Permeability of Bacteria to Antibacterial Agents

Nichols, W. W. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1400-1_26 · Cited by 14

Rational design of inhibitors of the bacterial cell wall synthetic enzyme GlmU using virtual screening and lead-hopping

Doig, P. C., Boriack‐Sjodin, P. A., Dumas, J., Hu, J., Itoh, K., Johnson, K., Kazmirski, S. L., Kinoshita, T., Kuroda, S., Sato, T., et al. (2014) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2014.08.017 · Cited by 14

Directional Porin Binding of Intrinsically Disordered Protein Sequences Promotes Colicin Epitope Display in the Bacterial Periplasm

Housden, N. G., Rassam, P., Lee, S., Samsudin, F., Kaminska, R., Sharp, C., Goult, J. D., Francis, M.-L. R., Khalid, S., Bayley, H., et al. (2018) · Biochemistry · doi:10.1021/acs.biochem.8b00621 · Cited by 14

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Chen, L., Wang, X., Fu, C.-M., & Wang, G. (2019) · BioMed Research International · doi:10.1155/2019/7851251 · Cited by 14

Applications of neutron reflectometry in biology

Gerelli, Y. (2020) · EPJ Web of Conferences · doi:10.1051/epjconf/202023604002 · Cited by 14

Antimicrobial resistance: Mechanism, causes, prevention and societal impact

Baweja, R. B., Singh, M., Shukla, S., Ravi, R., Ahmad, R., & Mishra, A. (2025) · The Microbe · doi:10.1016/j.microb.2025.100617 · Cited by 18

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Liang, S., Chen, H., Chen, Y., Ali, A. M. I., & Yao, S. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133094 · Cited by 13

Assessment of Antibiogram of Multidrug-Resistant Isolates of Enterobacter aerogenes after Biofield Energy Treatment

Trivedi, M. K., & Branton, A. (2015) · Journal of Pharmaceutical Care & Health Systems · doi:10.4172/2376-0419.1000145 · Cited by 13

Antimicrobial activity, toxicity and phytochemical screening of selected medicinal plants of Losho, Narok County, Kenya

Chalo, D. M., Lukhoba, C. W., Dossaji, S. F., & Nguta, J. M. (2017) · Biofarmasi Journal of Natural Product Biochemistry · doi:10.13057/biofar/f150106 · Cited by 13

Crystal structure of theAcinetobacter baumanniiouter membrane protein Omp33

Abellón‐Ruiz, J., Zahn, M., Baslé, A., & van den Berg, B. (2018) · Acta Crystallographica Section D Structural Biology · doi:10.1107/s205979831800904x · Cited by 13

High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB

Bartsch, A., Llabrés, S., Pein, F., Kattner, C., Schön, M., Diehn, M., Tanabe, M., Munk, A., Zachariae, U., & Steinem, C. (2019) · Scientific Reports · doi:10.1038/s41598-018-37066-9 · Cited by 13

Antibiotic‐dependent perturbations of extended spectrum beta‐lactamase producing Klebsiella pneumoniae proteome

Suh, M., Keasey, S. L., Brueggemann, E. E., & Ulrich, R. G. (2017) · PROTEOMICS · doi:10.1002/pmic.201700003 · Cited by 13

BaeR participates in cephalosporins susceptibility by regulating the expression level of outer membrane proteins in Escherichia coli

Wang, S., You, C., Memon, F. U., Zhang, G., Sun, Y., & Si, H. (2020) · The Journal of Biochemistry · doi:10.1093/jb/mvaa100 · Cited by 13

Comparative Phenotypic Analysis of Anabaena sp. PCC 7120 Mutants of Porinlike Genes

Schätzle, H., Brouwer, E., Liebhart, E., Stevanovic, M., & Schleiff, E. (2021) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2103.03009 · Cited by 13

The host outer membrane proteins OmpA and OmpC are associated with the Shigella phage Sf6 virion

Zhao, H., Sequeira, R. D., Galeva, N. A., & Tang, L. (2010) · Virology · doi:10.1016/j.virol.2010.10.030 · Cited by 13

Cpx-signalling in Yersinia pseudotuberculosis modulates Lipid-A remodelling and resistance to last-resort antimicrobials

Gahlot, D. K., Patkowski, J. B., de Santaella, J. F., Allsopp, L. P., Pan, Z., Filloux, A., Larrouy-Maumus, G. J., Francis, M. S., & Costa, T. R. D. (2024) · npj Antimicrobials and Resistance · doi:10.1038/s44259-024-00059-y · Cited by 12

Atmosphere-controlled high-voltage electrospray for improving conductivity, flexibility, and antibacterial properties of chitosan films

Yang, Q., Hu, Y., Wang, Y., Xu, B., Zhou, C., Adhikari, B., Liu, J., Xu, T., & Wang, B. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115450 · Cited by 12

Efflux Pumps and Porins Enhance Bacterial Tolerance to Phenolic Compounds by Inhibiting Hydroxyl Radical Generation

Sui, X., Guo, L., Bao, Z., Xian, M., & Zhao, G. (2025) · Microorganisms · doi:10.3390/microorganisms13010202 · Cited by 12

Biopolymeric self-assembled nanoparticles for enhanced antibacterial activity of Ag-based compounds

Dhanya, D., Scrivano, L., Parisi, O. I., Sinicropi, M. S., Fazio, A., Saturnino, C., Plutino, M. R., Cristo, F. D., Puoci, F., Cappello, A. R., et al. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.12.039 · Cited by 12

Permeation von kleinen Molekülen durch Membrankanäle: Chemische Modifikation zur Quantifizierung des Transports über OmpF

Wang, J., Bafna, J. A., Bhamidimarri, S. P., & Winterhalter, M. (2019) · Angewandte Chemie · doi:10.1002/ange.201814489 · Cited by 12

Surface-exposed loops L7 and L8 of Haemophilus (Glaesserella) parasuis OmpP2 contribute to the expression of proinflammatory cytokines in porcine alveolar macrophages

Zhou, Y., Feng, S., He, X., Zhou, Q., Wang, Y., Yue, H., Tang, C., & Zhang, B. (2019) · Veterinary Research · doi:10.1186/s13567-019-0721-4 · Cited by 12

Within-host evolution of a Klebsiella pneumoniae clone: selected mutations associated with the alteration of outer membrane protein expression conferred multidrug resistance

Aihara, M., Nishida, R., Akimoto, M., Gotoh, Y., Kiyosuke, M., Uchiumi, T., Nishioka, M., Matsushima, Y., Hayashi, T., & Kang, D. (2020) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkaa439 · Cited by 13

Proteomics profiling of ertapenem challenged major porin deficient carbapenem-resistant Klebsiella pneumoniae

Yuan, P., Ling, J.-H., Zhu, J.-H., Chen, P., Chen, E., Zhong, Y.-X., Liu, W.-T., Wang, L., Yang, L., & Chen, D. (2022) · Journal of Proteomics · doi:10.1016/j.jprot.2022.104715 · Cited by 12

Novel antimony-based antimicrobial drug targets membranes of Gram-positive and Gram-negative bacterial pathogens

Salpadoru, T., Pinks, K. E., Lieberman, J. A., Cotton, K., Wozniak, K. L., Gerasimchuk, N., & Patrauchan, M. A. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.04234-23 · Cited by 12

Discrimination of single‐porin Escherichia (E.) coli mutants by ATR and transmission mode FTIR spectroscopy

Saraiva, R. G., Lopes, J. A., Machado, J., Gameiro, P., & Feio, M. J. (2012) · Journal of Biophotonics · doi:10.1002/jbio.201200131 · Cited by 12

Mechanisms of carbapenem resistance among a collection of Enterobacteriaceae clinical isolates in a Texas city

Bennett, J. W., Mende, K., Herrera, M., Yu, X., Lewis, J. S., Wickes, B. L., Jorgensen, J. H., & Murray, C. K. (2010) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2009.11.013 · Cited by 12

Permeation through nanochannels: revealing fast kinetics

Mahendran, K. R., Singh, P. R., Arning, J., Stolte, S., Kleinekathöfer, U., & Winterhalter, M. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/45/454131 · Cited by 12

Metal Resistance in Bacteria from Contaminated Arctic Sediment is Driven by Metal Local Inputs

Caputo, S., Papale, M., Rizzo, C., Giannarelli, S., Conte, A., Moscheo, F., Graziano, M., Aspholm, P. E., Onor, M., Domenico, E. D., et al. (2019) · Archives of Environmental Contamination and Toxicology · doi:10.1007/s00244-019-00628-7 · Cited by 12

Glucose transport via the pseudomonad porin OprB: implications for the design of Trojan Horse anti-infectives

Coines, J., Acosta‐Gutiérrez, S., Bodrenko, I. V., Rovira, C., & Ceccarelli, M. (2019) · Physical Chemistry Chemical Physics · doi:10.1039/c9cp00778d · Cited by 12

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Zhao, D. W., & Lohans, C. T. (2025) · Antibiotics · doi:10.3390/antibiotics14050526 · Cited by 11

Porin-Mediated Carbapenem Resistance in Klebsiella pneumoniae: an Alarming Threat to Global Health

Gogoi, I., Puzari, M., & Chetia, P. (2023) · Current Clinical Microbiology Reports · doi:10.1007/s40588-023-00211-8 · Cited by 11

Nonlethal Molecular Nanomachines Potentiate Antibiotic Activity Against Gram-Negative Bacteria by Increasing Cell Permeability and Attenuating Efflux

Santos, A. L., Liu, D., van Venrooy, A. R., Beckham, J. L., Oliver, A., Tegos, G. P., & Tour, J. M. (2024) · ACS Nano · doi:10.1021/acsnano.3c08041 · Cited by 11

Inosine reverses multidrug resistance in Gram-negative bacteria carrying mobilized RND-type efflux pump gene cluster tmexCD-toprJ

Li, F., Xu, T., Fang, D., Wang, Z., & Liu, Y. (2024) · mSystems · doi:10.1128/msystems.00797-24 · Cited by 11

Fighting bacterial resistance: approaches, challenges, and opportunities in the search for new antibiotics.Part 1. Antibiotics used in clinical practice: mechanisms of action and the development of bacterial resistance

ZHIVICH, A. B. (2017) · Microbiology Independent Research Journal (MIR Journal) · doi:10.18527/2500-2236-2017-4-1-31-51 · Cited by 12

OmpC regulation differs between ST131 and non-ST131 Escherichia coli clinical isolates and involves differential expression of the small RNA MicC

Suelter, C. S., & Hanson, N. D. (2020) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkz566 · Cited by 10

Antibiotic-resistant bacteria in municipal sewage water joining river Ganga, at Prayagraj (India)

Kumar, A., Kumar, A., & Prasad, K. S. (2021) · Gene Reports · doi:10.1016/j.genrep.2021.101175 · Cited by 13

Exploiting neutron scattering contrast variation in biological membrane studies

Lakey, J. H., Paracini, N., & Clifton, L. A. (2022) · Biophysics Reviews · doi:10.1063/5.0091372 · Cited by 11

TurboID Screening of the OmpP2 Protein Reveals Host Proteins Involved in Recognition and Phagocytosis of Glaesserella parasuis by iPAM Cells

Jiang, C., Ma, N., Cao, H., Zeng, W., Ren, J., Hu, Y., Zhou, J., Zhang, M., Li, C., Lang, Y., et al. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.02307-22 · Cited by 11

Evasion of Antimicrobial Activity in Acinetobacter baumannii by Target Site Modifications: An Effective Resistance Mechanism

Martínez-Trejo, A., Ruiz-Ruiz, J. M., Gonzalez-Avila, L. U., Saldaña-Padilla, A., Hernández‐Cortez, C., Loyola-Cruz, M. Á., Bello–López, J. M., & Castro‐Escarpulli, G. (2022) · Vide Leaf, Hyderabad eBooks · doi:10.37247/pamol3ed.3.22.32 · Cited by 11

Optimization of the Antibacterial Spectrum and the Developability Profile of the Novel-Class Natural Product Corramycin

Renard, S., Versluys, S., Taillier, T., Dubarry, N., Leroi‐Geissler, C., Rey, A., Cornaire, É., Sordello, S., Carry, J., Angouillant-Boniface, O., et al. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c01564 · Cited by 10

Antibacterial and Anti-Quorum Sensing Activities of Selected Italian Honeys against Antibiotic-Resistant Pathogens

Fidaleo, M., Lavecchia, R., & Zuorro, A. (2015) · OnLine Journal of Biological Sciences · doi:10.3844/ojbsci.2015.236.243 · Cited by 11

Transport across the outer membrane porin of mycolic acid containing actinomycetales: Nocardia farcinica

Singh, P. R., Bajaj, H., Benz, R., Winterhalter, M., & Mahendran, K. R. (2014) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2014.11.020 · Cited by 11

Genome-Wide Analysis of the Pho Regulon in a pstCA Mutant of Citrobacter rodentium

Cheng, C., Wakefield, M. J., Yang, J. W., Tauschek, M., & Robins-Browne, R. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0050682 · Cited by 11

Antibacterial and Antifungal Plant Metabolites from the Tropical Medicinal Plants

da Silva, L. E., Confortin, C., & Swamy, M. K. (2020) · Advanced structured materials · doi:10.1007/978-3-030-54027-2_7 · Cited by 11

Hydrodynamic couplings of colloidal ellipsoids diffusing in channels

Zheng, Z., Xu, X., Wang, Y., & Han, Y. (2021) · Journal of Fluid Mechanics · doi:10.1017/jfm.2021.1062 · Cited by 11

Plant Secondary Metabolites for Tackling Antimicrobial Resistance: A Pharmacological Perspective

Maran, S., Yeo, W. W. Y., Lim, S. E., & Lai, K. (2022) · Springer eBooks · doi:10.1007/978-981-16-3120-7_6 · Cited by 12

The Outer Membrane Protein VhOmp of Vibrio harveyi: Pore-Forming Properties in Black Lipid Membranes

Schulte, A., Ruamchan, S., Khunkaewla, P., & Suginta, W. (2009) · The Journal of Membrane Biology · doi:10.1007/s00232-009-9194-0 · Cited by 11

Molecular analysis of porin gene transcription in heterogenotypic multidrug-resistant Escherichia coli isolates from scouring calves

Vinson, H. M., Gautam, A., Olet, S., Gibbs, P. S., & Barigye, R. (2010) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq246 · Cited by 11

Selection of KPC-2–producing Providencia stuartii during treatment for septicemia

Aires, C. A. M., Almeida, A. C. S., Vilela, M. A., de Morais, M. A., & de Morais, M. M. C. (2015) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2015.09.013 · Cited by 11

Porin flexibility in Providencia stuartii: cell-surface-exposed loops L5 and L7 are markers of Providencia porin OmpPst1

Tran, Q., Maigre, L., D’Agostino, T., Ceccarelli, M., Winterhalter, M., Pagès, J., & Davin‐Regli, A. (2017) · Research in Microbiology · doi:10.1016/j.resmic.2017.05.003 · Cited by 11

The Hybrid Antibiotic Thiomarinol A Overcomes Intrinsic Resistance in Escherichia coli Using a Privileged Dithiolopyrrolone Moiety

Johnson, R. M., Li, K., Chen, X., Morgan, G. L., Aubé, J., & Ли, Б. (2024) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.3c00504 · Cited by 10

Antimicrobials: An update on new strategies to diversify treatment for bacterial infections

Hibbert, T. M., Krpetić, Ž., Latimer, J., Leighton, H. J., McHugh, R. E., Pottenger, S., Wragg, C., & James, C. E. (2024) · Advances in microbial physiology/Advances in Microbial Physiology · doi:10.1016/bs.ampbs.2023.12.002 · Cited by 10

Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa

Scorciapino, M. A., Malloci, G., Serra, I., Milenkovic, S., Moynié, L., Naismith, J. H., Desarbre, E., Page, M. G. P., & Ceccarelli, M. (2019) · BioMetals · doi:10.1007/s10534-018-00166-0 · Cited by 10

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Paracini, N., Clifton, L. A., & Lakey, J. H. (2020) · Biochemical Society Transactions · doi:10.1042/bst20200320 · Cited by 10

Millisecond-Long Simulations of Antibiotics Transport through Outer Membrane Channels

Golla, V. K., Prajapati, J. D., & Kleinekathöfer, U. (2020) · Journal of Chemical Theory and Computation · doi:10.1021/acs.jctc.0c01088 · Cited by 10

Yersinia pseudotuberculosis doxycycline tolerance strategies include modulating expression of genes involved in cell permeability and tRNA modifications

Álvarez-Manzo, H. S., Davidson, R. K., de Wyels, J. V. C., Cotten, K. L., Nguyen, B. H., Xiao, M., Zhu, Z., Anthony, J. S., van Opijnen, T., & Davis, K. M. (2022) · PLoS Pathogens · doi:10.1371/journal.ppat.1010556 · Cited by 9

Monograph: In vitro efficacy of 30 ethnomedicinal plants used by Indian aborigines against 6 multidrug resistant Gram-positive pathogenic bacteria

Sahu, M. C., Dubey, D., Rath, S., Panda, T., & Padhy, R. N. (2014) · Asian Pacific Journal of Tropical Disease · doi:10.1016/s2222-1808(14)60641-1 · Cited by 10

Tunable accessibility of dye-doped liposomes towards gold nanoparticles for fluorescence sensing of lipopolysaccharide

Gao, J., Li, Z., Zhang, O., Wu, C., & Zhao, Y. (2017) · The Analyst · doi:10.1039/c7an00019g · Cited by 10

Optimization of the biotechnological production of a novel class of anti-MRSA antibiotics from Chitinophaga sancti

Beckmann, A., Hüttel, S., Schmitt, V., Müller, R., & Stadler, M. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0756-z · Cited by 11

Free energy calculations and molecular properties of substrate translocation through OccAB porins

Benkerrou, D., & Ceccarelli, M. (2018) · Physical Chemistry Chemical Physics · doi:10.1039/c7cp08299a · Cited by 10

Targeted lipopolysaccharide biosynthetic intermediate analysis with normal-phase liquid chromatography mass spectrometry

Sawyer, W. S., Wang, L., Uehara, T., Tamrakar, P., Prathapam, R., Mostafavi, M., Metzger, L. E., Feng, B. Y., & Rath, C. M. B. (2019) · PLoS ONE · doi:10.1371/journal.pone.0211803 · Cited by 9

Effects of Polyethyelene Glycol-Desferrioxamine:Gallium Conjugates on Pseudomonas aeruginosa Outer Membrane Permeability and Vancomycin Potentiation

Qiao, J., Purro, M., Liu, Z., & Xiong, M. P. (2020) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.0c00820 · Cited by 10

Development of the computational antibiotic screening platform (CLASP) to aid in the discovery of new antibiotics

Dai, Y., Ma, H., Wu, M., Welsch, T. A., Vora, S. R., Ren, D., & Nangia, S. (2021) · Soft Matter · doi:10.1039/d0sm02035d · Cited by 8

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Sato, J., Kusano, H., Aoki, T., Shibuya, S., Yokoo, K., Komano, K., Oguma, T., Matsumoto, S., Nakamura, R., Sato, T., et al. (2022) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.1c00549 · Cited by 10

Liquid Chromatography-Tandem Mass Spectrometry Analysis Demonstrates a Decrease in Porins and Increase in CMY-2 β-Lactamases in Escherichia coli Exposed to Increasing Concentrations of Meropenem

Foudraine, D. E., Aarents, C. N. M., Wattel, A. A., van Boxtel, R., Strepis, N., ten Kate, M. T., Verbon, A., Luider, T. M., Klaassen, C. H. W., Hays, J. P., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.793738 · Cited by 10

Profiling of bacterial transcriptome from ultra‐low input with MiniBac ‐seq

Wang, T., Shen, P., Chai, R., He, Y., & Liu, J. (2022) · Environmental Microbiology · doi:10.1111/1462-2920.16169 · Cited by 10

Cefovecin: A New Long-acting Cephalosporin

Wernick, M. B., & Müntener, C. R. (2010) · Journal of Exotic Pet Medicine · doi:10.1053/j.jepm.2010.10.002 · Cited by 10

Structural and Kinetic Insights into the “Ceftazidimase” Behavior of the Extended-Spectrum β-Lactamase CTX-M-96

Ghiglione, B., Rodríguez, M. M., Herman, R., Curto, L. M., Dropa, M., Bouillenne, F., Kerff, F., Galleni, M., Charlier, P., Gutkind, G., et al. (2015) · Biochemistry · doi:10.1021/acs.biochem.5b00313 · Cited by 10

Switchable Control of Antibiotic Activity: A Shape-Shifting “Tail” Strategy

Chang, J., Chen, Y., Xu, Z., Wang, Z. J., Zeng, Q., & Fan, H. (2017) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.7b00599 · Cited by 10

Medicinal Chemistry of β‐Lactam Antibiotics

Testero, S. A., Llarrull, L. I., Fisher, J. F., & Mobashery, S. (2021) · Wiley eBooks · doi:10.1002/0471266949.bmc226.pub2 · Cited by 11

Proline-Hinged α-Helical Peptides Sensitize Gram-Positive Antibiotics, Expanding Their Physicochemical Properties to Be Used as Gram-Negative Antibiotics

Choi, Y., Choe, H. W., Kook, M., Choo, S., Park, T. W., Bae, S., Kim, H., Yang, J.-H., Jeong, W.-S., Yu, J., et al. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c01473 · Cited by 9

Evaluation of immunogenicity and protective efficacy of the outer membrane porin F (OprF) against Pseudomonas plecoglossicida in large yellow croaker (Larimichthys crocea)

He, L., Kang, J., Chen, X., Qin, P., & Chen, X. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109427 · Cited by 9

The Impact of Vp-Porin, an Outer Membrane Protein, on the Biological Characteristics and Virulence of Vibrio Parahaemolyticus

Che, J., Fang, Q., Hu, S., Liu, B., Wang, L., Fang, X., Li, L., Luo, T., & Bao, B. (2024) · Biology · doi:10.3390/biology13070485 · Cited by 9

Enterobacter hormaechei replaces virulence with carbapenem resistance via porin loss

Perault, A. I., John, A. S., Dumont, A., Shopsin, B., Pironti, A., & Torres, V. J. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2414315122 · Cited by 9

Click-based determination of accumulation of molecules in Escherichia coli

Ongwae, G. M., Liu, Z., Feng, S., Chordia, M. D., Dash, R., He, Y., Gh., M. S., Dalesandro, B. E., Guo, T., Sharpless, K. B., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-68717-5 · Cited by 9

Assessment of combination therapy in BALB/c mice injected with carbapenem-resistant Enterobacteriaceae strains

Salloum, N. A., Kissoyan, K. A. B., Fadlallah, S. M., Cheaito, K. A., Araj, G. F., Wakim, R. H., Kanj, S. S., Kanafani, Z. A., Dbaibo, G. S., & Matar, G. M. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00999 · Cited by 9

Preparation of functionalised monobactams from pyridones

Adamo, M. F. A., Disetti, P., & Piras, L. (2009) · Tetrahedron Letters · doi:10.1016/j.tetlet.2009.03.045 · Cited by 9

Permeation of β-Lactamase Inhibitors through the General Porins of Gram-Negative Bacteria

Pira, A., Scorciapino, M. A., Bodrenko, I. V., Bosin, A., Acosta‐Gutiérrez, S., & Ceccarelli, M. (2020) · Molecules · doi:10.3390/molecules25235747 · Cited by 9

Total Synthesis and Antibiotic Properties of Amino‐Functionalized Aromatic Terpenoids Related to Erogorgiaene and the Pseudopterosins

Schumacher, C. E., Rausch, M. D., Greven, T., Neudörfl, J., Schneider, T., & Schmalz, H. (2022) · European Journal of Organic Chemistry · doi:10.1002/ejoc.202200058 · Cited by 9

Modified Outer Membrane Protein-G Nanopores with Expanded and Truncated β-Hairpins for Recognition of Double-Stranded DNA

Tosaka, T., & Kamiya, K. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c04417 · Cited by 9

Purine metabolism regulates Vibrio splendidus persistence associated with protein aggresome formation and intracellular tetracycline efflux

Li, Y., Wood, T. K., Zhang, W., & Li, C. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1127018 · Cited by 9

The synergistic antibacterial activity and mechanism of colistin-oxethazaine combination against gram-negative pathogens

Li, J., Han, N., Li, Y., Zhao, F., Xiong, W., & Zeng, Z. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1363441 · Cited by 9

Transcriptomic analysis displays the effect of (-)-roemerine on the motility and nutrient uptake in Escherichia coli

Ayyildiz, D., Arğa, K. Y., Avcı, F. G., Kaya, F. E. A., Ünsal, Ç., Toplan, G. G., Kazan, D., Wozny, K., Brügger, B., Mertoğlu, B., et al. (2016) · Current Genetics · doi:10.1007/s00294-016-0673-4 · Cited by 9

Comparative subproteomic analysis of clinically acquired fluoroquinolone resistance and ciprofloxacin stress in Salmonella Typhimurium DT104B

Correia, S., Hébraud, M., Chafsey, I., Chambon, C., Viala, D., Sáenz, Y., Capelo, J. L., Poeta, P. A. C. Q. D., & Igrejas, G. (2017) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201600107 · Cited by 9

A Novel Regulatory Cascade Involving BluR, YcgZ, and Lon Controls the Expression of Escherichia coli OmpF Porin

Duval, V., Foster, K. A., Brewster, J., & Levy, S. B. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01148 · Cited by 9

Manipulation of charge distribution in the arginine and glutamate clusters of the OmpG pore alters sugar specificity and ion selectivity

Schmitt, C., Bafna, J. A., Schmid, B., Klingl, S., Baier, S., Hemmis, B., Wagner, R., Winterhalter, M., & Voll, L. M. (2019) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2019.07.009 · Cited by 9

Antibiotic resistance

Scott, G. M. (2009) · Medicine · doi:10.1016/j.mpmed.2009.07.013 · Cited by 9

Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli

Du, G., Dong, Y., Fan, X., Yin, A., Le, Y.-J., & Yang, X.-Y. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01093-22 · Cited by 8

Mutations in the essential outer membrane protein BamA contribute to Escherichia coli resistance to the antimicrobial peptide TAT-RasGAP317-326

Georgieva, M., Stojceski, F., Wüthrich, F., Sosthène, C., Pérez, L. B., Grasso, G., & Jacquier, N. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.108018 · Cited by 8

Helicobacter pylori outer membrane protein families and related pathogenesis

You, S., Li, J. J., Chua, E. G., Tay, C. Y., Benghezal, M., Marshall, B. J., Hong, T., & Li, H. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107740 · Cited by 8

Prokaryotic and eukaryotic traits support the biological role of the chloroplast outer envelope

Barth, M. A., Soll, J., & Akbaş, Ş. (2022) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2022.119224 · Cited by 8

Submarine Outfalls of Treated Wastewater Effluents are Sources of Extensively- and Multidrug-Resistant KPC- and OXA-48-Producing Enterobacteriaceae in Coastal Marine Environment

Kvesić, M., Šamanić, I., Novak, A., Fredotović, Ž., Dželalija, M., Kamenjarin, J., Goić-Barišić, I., Tonkić, M., & Maravić, A. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.858821 · Cited by 8

Reduced porin expression with EnvZ-OmpR, PhoPQ, BaeSR two-component system down-regulation in carbapenem resistance of Klebsiella Pneumoniae based on proteomic analysis

Zhang, K., Liu, L., Yang, M., Chen, C., Li, X., Tian, J., Luo, C., Wang, X., & Wang, M. (2022) · Microbial Pathogenesis · doi:10.1016/j.micpath.2022.105686 · Cited by 8

Quantum dot-based fluorescence-linked immunosorbent assay for the rapid detection of lomefloxacin in animal-derived foods

Wang, A., Wen, Y., Zhu, X., Zhou, J., Chen, Y., Liu, H., Liang, C., Liu, E., Zhang, Y., Ai, G., et al. (2024) · Food Additives & Contaminants Part A · doi:10.1080/19440049.2023.2267144 · Cited by 8

Impact of Antimicrobial Resistance in Health and Economic Outcomes: A Review

Upaganlawar, A. B. (2024) · Advances in Pharmacology & Clinical Trials · doi:10.23880/apct-16000234 · Cited by 7

Seeking Correlation Among Porin Permeabilities and Minimum Inhibitory Concentrations Through Machine Learning: A Promising Route to the Essential Molecular Descriptors

Boi, S., Puxeddu, S., Delogu, I., Farci, D., Piano, D., Manzin, A., Ceccarelli, M., Angius, F., Scorciapino, M. A., & Milenkovic, S. (2025) · Molecules · doi:10.3390/molecules30061224 · Cited by 8

Mechanisms Determining Bacterial Biofilm Resistance to Antimicrobial Factors

Myszka, K., & Czaczyk, K. (2012) · InTech eBooks · doi:10.5772/33048 · Cited by 8

Exploring bacterial outer membrane barrier to combat bad bugs

Ghai, I., & Ghai, S. (2017) · Infection and Drug Resistance · doi:10.2147/idr.s144299 · Cited by 47

A Barrier to Entry: Examining the Bacterial Outer Membrane and Antibiotic Resistance

Ghai, I. (2023) · Applied Sciences · doi:10.3390/app13074238 · Cited by 54

Bacterial resistance to antibiotics as a function of outer membrane permeability

Nikaido, H. (1988) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/22.supplement_a.17 · Cited by 49

The Possible Role of Porins in Bacterial Antibiotic Resistance

Gutmann, L., Williamson, R., & Collatz, E. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-101-4-554 · Cited by 13

Understanding antibiotic resistance via outer membrane permeability

Ghai, I., & Ghai, S. (2018) · Infection and Drug Resistance · doi:10.2147/idr.s156995 · Cited by 207