The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
ppGpp: magic beyond RNA polymerase
Open accessAbstract
During stress, bacteria undergo extensive physiological transformations, many of which are coordinated by ppGpp. Although ppGpp is best known for enhancing cellular resilience by redirecting the RNA polymerase (RNAP) to certain genes, it also acts as a signal in many other cellular processes in bacteria. After a brief overview of ppGpp biosynthesis and its impact on promoter selection by RNAP, we discuss how bacteria exploit ppGpp to modulate the synthesis, stability or activity of proteins or regulatory RNAs that are crucial in challenging environments, using mechanisms beyond the direct regulation of RNAP activity.
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Cites
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Cited by
Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence
Moradali, M. F., Ghods, S., & Rehm, B. H. A. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00039 · Cited by 1,537
Biofilm infections, their resilience to therapy and innovative treatment strategies
Römling, U., & Balsalobre, C. (2012) · Journal of Internal Medicine · doi:10.1111/joim.12004 · Cited by 865
Castelle, C. J., Wrighton, K. C., Thomas, B. C., Hug, L. A., Brown, C. T., Wilkins, M. J., Frischkorn, K. R., Tringe, S. G., Singh, A., Markillie, L. M., et al. (2015) · Current Biology · doi:10.1016/j.cub.2015.01.014 · Cited by 536
Polymyxin: Alternative Mechanisms of Action and Resistance
Trimble, M. J., Mlynárčik, P., Kolář, M., & Hancock, R. E. W. (2016) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025288 · Cited by 454
The stringent response and physiological roles of (pp)pGpp in bacteria.
Irving, S. E., Choudhury, N. R., & Corrigan, R. M. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-00470-y · Cited by 413
Metadata
- Authors
- Dalebroux, Z. D., & Swanson, M. S.
- Venue
- Nature Reviews Microbiology
- Published
- 2012-02-16
- Volume
- 10
- Issue
- 3
- Pages
- 203-212
- ISSN
- 1740-1526 (ISSN-L)
- 1740-1534
- OpenAlex
- W1986842298
- Cited by
- 433
- References
- 84
- FWCI
- 3.74
- Type
- journal article
- Language
- en
- Open access
- green
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