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The molecular logic of endocannabinoid signalling
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“Fatty acid amide hydrolase (FAAH) catalyzes the intracellular hydrolysis of the endocannabinoid anandamide.”
From Enhancement of anandamide-mediated endocannabinoid signaling corrects autism-related social impairment (2016) · cites this paper as [11]
In the citing paper
“This view is consistent with the presence of CB1 receptors on presynaptic terminals of both glutamatergic projection neurons and GABAergic interneurons.11”
From Enhancement of anandamide-mediated endocannabinoid signaling corrects autism-related social impairment (2016) · cites this paper as [11]
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“In contrast, CB 2 receptors are primarily expressed in immune cells, including myeloid, macrophage, microglia, lymphoid, and mast cells (Piomelli, 2003).”
From The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain (2018) · cites this paper as Piomelli, 2003
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Metadata
- Authors
- Piomelli, D.
- Affiliations
- University of California, Irvine (US)
- Corresponding author
- Piomelli, Daniele
- ORCID
- Piomelli, Daniele
- Venue
- Nature Reviews Neuroscience
- Published
- 2003-11
- Volume
- 4
- Issue
- 11
- Pages
- 873-884
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2080649553
- Cited by
- 1,957
- References
- 152
- Citations by year
- 2026: 39 · 2025: 42 · 2024: 43 · 2023: 50 · 2022: 76 · 2021: 77 · 2020: 81 · 2019: 71 · 2018: 67 · 2017: 79 · 2016: 81 · 2015: 100 · 2014: 100 · 2013: 95 · 2012: 108
- FWCI
- 9.35
- Type
- journal article
- Language
- en
- Open access
- green
- escholarship.org
- Licence
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cannabis and Cannabinoid Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Keywords
- endocannabinoids, endocannabinoid signaling, CB1 receptor, delta-9-tetrahydrocannabinol, cannabinoid receptors, neurotransmitter release, ion channel modulation, synaptic plasticity, axon terminals
- MeSH terms
- Animals, Cannabis, gamma-Aminobutyric Acid, Hallucinogens, Humans, Synaptic Transmission, Dronabinol, Signal Transduction, Neurotransmitter Agents, Glutamic Acid, Receptor, Cannabinoid, CB1, Cannabinoid Receptor Modulators, Endocannabinoids
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