Piomelli, Daniele

The molecular logic of endocannabinoid signalling

Piomelli, D. (2003) · Nature Reviews Neuroscience

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,957

A second endogenous cannabinoid that modulates long-term potentiation

Stella, N., Schweitzer, P., & Piomelli, D. (1997) · Nature

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,496

Identification and Functional Characterization of Brainstem Cannabinoid CB2Receptors

Van Sickle, M. D., Duncan, M., Kingsley, P. J., Mouihate, A., Urbani, P., Mackie, K., Stella, N., Makriyannis, A., Piomelli, D., Davison, J. S., et al. (2005) · Science

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,470

Brain monoglyceride lipase participating in endocannabinoid inactivation

Dinh, T. P., Carpenter, D., Leslie, F. M., Freund, T. F., Katona, I., Sensi, S. L., Kathuria, S., & Piomelli, D. (2002) · Proceedings of the National Academy of Sciences

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,373

Modulation of anxiety through blockade of anandamide hydrolysis

Kathuria, S., Gaetani, S., Fegley, D., Valiño, F., Duranti, A., Tontini, A., Mor, M., Tarzia, G., Rana, G. L., Calignano, A., et al. (2003) · Nature Medicine

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 1,293

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

Leweke, F. M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C. W., Hoyer, C., Klosterkötter, J., Hellmich, M., & Koethe, D. (2012) · Translational Psychiatry

Cannabis and Cannabinoid ResearchSchizophrenia research and treatment

Cited by 1,059

The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide

Lo Verme, J., Fu, J., Astarita, G., La Rana, G., Russo, R., Calignano, A., & Piomelli, D. (2005) · Molecular Pharmacology

Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health

Cited by 882

Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition

Beltramo, M., Stella, N., Calignano, A., Lin, S. Y., Makriyannis, A., & Piomelli, D. (1997) · Science

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 813

An endocannabinoid mechanism for stress-induced analgesia

Hohmann, A. G., Suplita, R. L., Bolton, N. M., Neely, M. H., Fegley, D., Mangieri, R., Krey, J. F., Michael Walker, J., Holmes, P. V., Crystal, J. D., et al. (2005) · Nature

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 778

Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala

Gulyas, A. I., Cravatt, B. F., Bracey, M. H., Dinh, T. P., Piomelli, D., Boscia, F., & Freund, T. F. (2004) · European Journal of Neuroscience

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 561

Molecular Composition of the Endocannabinoid System at Glutamatergic Synapses

Katona, I., Urbán, G. M., Wallace, M., Ledent, C., Jung, K.-M., Piomelli, D., Mackie, K., & Freund, T. F. (2006) · The Journal of Neuroscience

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 511

PER2 controls lipid metabolism by direct regulation of PPARγ

Grimaldi, B., Bellet, M. M., Katada, S., Astarita, G., Hirayama, J., Amin, R. H., Granneman, J. G., Piomelli, D., Leff, T., & Sassone-Corsi, P. (2010) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsCircadian rhythm and melatonin

Cited by 489

Characterization of the Fatty Acid Amide Hydrolase Inhibitor Cyclohexyl Carbamic Acid 3′-Carbamoyl-biphenyl-3-yl Ester (URB597): Effects on Anandamide and Oleoylethanolamide Deactivation

Fegley, D., Gaetani, S., Duranti, A., Tontini, A., Mor, M., Tarzia, G., & Piomelli, D. (2005) · The Journal of Pharmacology and Experimental Therapeutics

Cannabis and Cannabinoid ResearchEicosanoids and Hypertension Pharmacology

Cited by 427

The endocannabinoid system as a target for therapeutic drugs

Piomelli, D., Giuffrida, A., Calignano, A., & Rodrı́guez de Fonseca, F. (2000) · Trends in Pharmacological Sciences

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 421

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: A positron emission tomography study

Neumeister, A., Normandin, M. D., Pietrzak, R. H., Piomelli, D., Zheng, M. Q., Gujarro-Anton, A., Potenza, M. N., Bailey, C. R., Lin, S. F., Najafzadeh, S., et al. (2013) · Molecular Psychiatry

Cannabis and Cannabinoid ResearchPosttraumatic Stress Disorder Research

Cited by 361

Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress

Bortolato, M., Mangieri, R. A., Fu, J., Kim, J. H., Arguello, O., Duranti, A., Tontini, A., Mor, M., Tarzia, G., & Piomelli, D. (2007) · Biological Psychiatry

Cannabis and Cannabinoid ResearchTreatment of Major Depression

Cited by 347

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism

Clapper, J. R., Moreno-Sanz, G., Russo, R., Guijarro, A., Vacondio, F., Duranti, A., Tontini, A., Sanchini, S., Sciolino, N. R., Spradley, J. M., et al. (2010) · Nature Neuroscience

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 346

Anandamide Amidohydrolase Activity in Rat Brain Microsomes

Desarnaud, F., Cadas, H., & Piomelli, D. (1995) · Journal of Biological Chemistry

Cannabis and Cannabinoid ResearchEicosanoids and Hypertension Pharmacology

Cited by 336

Oleoylethanolamide Stimulates Lipolysis by Activating the Nuclear Receptor Peroxisome Proliferator-activated Receptor α (PPAR-α)

Guzmán, M., Lo Verme, J., Fu, J., Oveisi, F., Blázquez, C., & Piomelli, D. (2004) · Journal of Biological Chemistry

Peroxisome Proliferator-Activated ReceptorsFatty Acid Research and Health

Cited by 328

Rapid Broad-Spectrum Analgesia through Activation of Peroxisome Proliferator-Activated Receptor-α

LoVerme, J., Russo, R., La Rana, G., Fu, J., Farthing, J., Mattace-Raso, G., Meli, R., Hohmann, A., Calignano, A., & Piomelli, D. (2006) · The Journal of Pharmacology and Experimental Therapeutics

Pain Mechanisms and TreatmentsPeroxisome Proliferator-Activated Receptors

Cited by 316

Exercise activates the endocannabinoid system

Sparling, P. B., Giuffrida, A., Piomelli, D., Rosskopf, L., & Dietrich, A. (2003) · Neuroreport

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 313

Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models

Jayamanne, A., Greenwood, R., Mitchell, V. A., Aslan, S., Piomelli, D., & Vaughan, C. W. (2006) · British Journal of Pharmacology

Cannabis and Cannabinoid ResearchPain Mechanisms and Treatments

Cited by 287

Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172

Fegley, D., Kathuria, S., Mercier, R., Li, C., Goutopoulos, A., Makriyannis, A., & Piomelli, D. (2004) · Proceedings of the National Academy of Sciences

Cannabis and Cannabinoid ResearchNeuroscience and Neuropharmacology Research

Cited by 230

Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

Astarita, G., Jung, K.-M., Berchtold, N. C., Nguyen, V. Q., Gillen, D. L., Head, E., Cotman, C. W., & Piomelli, D. (2010) · PLoS ONE

Fatty Acid Research and HealthAlzheimer's disease research and treatments

Cited by 218