The DOI matches its Crossref record; 120 of the 120 references it cites were found in a registry or an index.
Pain and emotion interactions in subregions of the cingulate gyrus
Open accessAbstract
Acute pain and emotion are processed in two forebrain networks, and the cingulate cortex is involved in both. Although Brodmann's cingulate gyrus had two divisions and was not based on any functional criteria, functional imaging studies still use this model. However, recent cytoarchitectural studies of the cingulate gyrus support a four-region model, with subregions, that is based on connections and qualitatively unique functions. Although the activity evoked by pain and emotion has been widely reported, some view them as emergent products of the brain rather than of small aggregates of neurons. Here, we assess pain and emotion in each cingulate subregion, and assess whether pain is co-localized with negative affect. Amazingly, these activation patterns do not simply overlap.
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“The pACC and sACC have known affective function and are thought to instantiate the visceromotor responses observed during classical conditioning, pain, and affective behaviors (Devinksy et al. 1995; Vogt 2005).”
From The brain basis of emotion: a meta-analytic review (2012) · cites this paper as Vogt 2005
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“Finally, pACC is implicated in pain, perhaps because it supports the feeling of “suffering” (cf. Vogt 2005).”
From The brain basis of emotion: a meta-analytic review (2012) · cites this paper as Vogt 2005
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“which are involved in negative affect (Vogt, 2005)”
From Oxytocin Facilitates Pavlovian Fear Learning in Males (2016) · cites this paper as Vogt, 2005
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“the hypothesized role of this region in 'orienting the body toward innocuous and noxious somatosensory stimuli' (Vogt, 2005).”
From Oxytocin Facilitates Pavlovian Fear Learning in Males (2016) · cites this paper as Vogt, 2005
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“Pain intensity ratings were additionally associated with activation in contralateral precentral gyrus, and in dorsal posterior cingulate gyrus in a region involved in visuo-spatial attention [32].”
From What are you feeling? Using functional magnetic resonance imaging to assess the modulation of sensory and affective responses during empathy for pain (2007) · cites this paper as [32]
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Cites
Selective Cortical Undercutting As a Means of Modifying and Studying Frontal Lobe Function in Man
Scoville, W. B. (1949) · Journal of neurosurgery · doi:10.3171/jns.1949.6.1.0065 · Cited by 7,374
Handbook of Affective Sciences
(2002) · doi:10.1093/oso/9780195126013.001.0001 · Cited by 5,113
Handbook of Chemical Neuroanatomy
Stern, C. D. (1986) · Neurochemistry International · doi:10.1016/0197-0186(86)90021-5 · Cited by 4,160
Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI
Phan, K. L., Wager, T., Taylor, S. F., & Liberzon, I. (2002) · NeuroImage · doi:10.1006/nimg.2002.1087 · Cited by 3,502
Pain Affect Encoded in Human Anterior Cingulate But Not Somatosensory Cortex
Rainville, P., Duncan, G. H., Price, D. D., Carrier, B., & Bushnell, M. C. (1997) · Science · doi:10.1126/science.277.5328.968 · Cited by 2,629
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416
Whalen, P. J., Rauch, S. L., Etcoff, N. L., McInerney, S. C., Lee, M. B., & Jenike, M. A. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-01-00411.1998 · Cited by 2,205
Functional imaging of brain responses to pain. A review and meta-analysis (2000)
Peyron, R., Laurent, B., & García-Larrea, L. (2000) · Neurophysiologie Clinique/Clinical Neurophysiology · doi:10.1016/s0987-7053(00)00227-6 · Cited by 2,171
Subcortical and cortical brain activity during the feeling of self-generated emotions
Damasio, A. R., Grabowski, T. J., Bechara, A., Damasio, H., Ponto, L. L. B., Parvizi, J., & Hichwa, R. D. (2000) · Nature Neuroscience · doi:10.1038/79871 · Cited by 2,117
A differential neural response in the human amygdala to fearful and happy facial expressions
Morris, J. S., Frith, C. D., Perrett, D. I., Rowland, D., Young, A. W., Calder, A. J., & Dolan, R. J. (1996) · Nature · doi:10.1038/383812a0 · Cited by 2,013
Research works printed but not linked: 1
- Aggleton, J. P. The Amygdala (Oxford Univ. Press, New York, USA, 2001).
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De Pascalis, V., Varriale, V., & Cacace, I. (2015) · PLOS ONE · doi:10.1371/journal.pone.0128474 · Cited by 20
Multidisciplinary treatment for hypermobile adolescents with chronic musculoskeletal pain
Meulenbroek, T., Conijn, A., Huijnen, I., Engelbert, R., & Verbunt, J. (2020) · Journal of Rehabilitation Medicine – Clinical Communications · doi:10.2340/20030711-1000033 · Cited by 16
Performance monitoring during a minimal group manipulation
Pfabigan, D. M., Holzner, M.-T., & Lamm, C. (2016) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsw071 · Cited by 9
Metadata
- Authors
- Vogt, B. A.
- Affiliations
- SUNY Upstate Medical University (US)
- Corresponding author
- Vogt, Brent A.
- ORCID
- Vogt, Brent A.
- Venue
- Nature Reviews Neuroscience
- Published
- 2005-07
- Volume
- 6
- Issue
- 7
- Pages
- 533-544
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- PMC
- PMC2659949
- OpenAlex
- W2028850601
- Cited by
- 1,810
- References
- 118
- Citations by year
- 2026: 69 · 2025: 77 · 2024: 60 · 2023: 83 · 2022: 78 · 2021: 101 · 2020: 87 · 2019: 88 · 2018: 75 · 2017: 108 · 2016: 100 · 2015: 93 · 2014: 98 · 2013: 109 · 2012: 108
- FWCI
- 7.91
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (R01NS044222)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Keywords
- cingulate gyrus, pain, emotions, negative affect, Brodmann areas, brain networks, cytoarchitecture
- MeSH terms
- Animals, Brain Mapping, Emotions, Gyrus Cinguli, Humans, Models, Biological, Neurons, Afferent, Nociceptors, Pain
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