The DOI matches its Crossref record; 185 of the 185 references it cites were found in a registry or an index.
Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour
Abstract
Williams syndrome, a rare disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, has long intrigued neuroscientists with its unique combination of striking behavioural abnormalities, such as hypersociability, and characteristic neurocognitive profile. Williams syndrome, therefore, raises fundamental questions about the neural mechanisms of social behaviour, the modularity of mind and brain development, and provides a privileged setting to understand genetic influences on complex brain functions in a 'bottom-up' way. We review recent advances in uncovering the functional and structural neural substrates of Williams syndrome that provide an emerging understanding of how these are related to dissociable genetic contributions characterized both in special participant populations and animal models.
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“There are currently three models of social function in WS: 1) heightened drive towards non-specific social interaction (for example, social interactions with strangers) [686,687], 2) heightened emotional responsiveness [685], and 3) social fearlessness [688].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [688]
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Cites
Fodor, J. A. (1983) · doi:10.7551/mitpress/4737.001.0001 · Cited by 7,734
Ingle, D., Goodale, M. A., & Mansfield, R. J. W. (1982) · The MIT Press eBooks · Cited by 4,118
Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00035-7 · Cited by 3,888
Beyond modularity: a developmental perspective on cognitive science
Karmiloff‐Smith, A. (1993) · Choice Reviews Online · doi:10.5860/choice.30-5872 · Cited by 2,594
Matthei, E. H. (1984) · Language · doi:10.2307/413815 · Cited by 2,189
Karmiloff‐Smith, A. (1992) · The MIT Press eBooks · doi:10.7551/mitpress/1579.001.0001 · Cited by 2,078
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977
The Emotional Brain, Fear, and the Amygdala
LeDoux, J. (2003) · Cellular and Molecular Neurobiology · doi:10.1023/a:1025048802629 · Cited by 1,818
A tension-based theory of morphogenesis and compact wiring in the central nervous system
Essen, D. C. V. (1997) · Nature · doi:10.1038/385313a0 · Cited by 1,668
Cognitive neuroscience of human social behaviour
Adolphs, R. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1056 · Cited by 1,657
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Research works printed but not linked: 7
- Marenco, S. et al. Preliminary diffusion tensor imaging (DTI) observations in 5 individuals with Williams syndrome (WS). Neuroimage 22 (Suppl. 1), M0363 (2004).
- Olsen, R. K. et al. Retinotopic mapping of early visual areas in Williams syndrome. Presented at the Human Brain Mapping Meeting 2003 (New York, USA). Neuroimage 19 (Suppl. 1), 1550 (2003).
- Nardini, M., Breckenridge, K. E., Eastwood, R. L., Atkinson, J. & Braddick, O. J. Distinct developmental trajectories in three systems for spatial encoding between the ages of 3 and 6 years. Perception S33, 28b (2004).
- Lukács, A., Racsmány, M. & Pléh, C. Vocabulary and morphological patterns in Hungarian children with Williams syndrome: a preliminary report. Acta Linguistica Hungarica 48, 243–269 (2001).
- Mons, A. W., Wilmowski, W. A. & Detweiler, C. Williams Syndrome: a Highly Musical Species (EO Productions International, 1996).
- Gordon, F. E. in Musical Aptitude Profile (Houghton Mifflin, Boston, 1995).
- Gordon, F. E. Primary Measures of Music Audiation (G. I. A. Publications, Chicago, 1980).
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Zhou, J., Greicius, M. D., Gennatas, E. D., Growdon, M. E., Jang, J. Y., Rabinovici, G. D., Kramer, J. H., Weiner, M., Miller, B. L., & Seeley, W. W. (2010) · Brain · doi:10.1093/brain/awq075 · Cited by 1,016
Pober, B. R. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0903074 · Cited by 848
The social brain in psychiatric and neurological disorders
Kennedy, D. P., & Adolphs, R. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2012.09.006 · Cited by 846
Using developmental trajectories to understand developmental disorders.
Thomas, M., Annaz, D., Ansari, D., Scerif, G., Jarrold, C., & Karmiloff-Smith, A. (2009) · Journal of Speech, Language and Hearing Research · doi:10.1044/1092-4388(2009/07-0144 · Cited by 573
Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
Petrovic, P., Kalisch, R., Singer, T., & Dolan, R. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4572-07.2008 · Cited by 424
“Patients with Williams syndrome show high sociability and empathy (Meyer-Lindenberg et al., 2006), whereas autistic people show impaired social functioning (Hill and Frith, 2003).”
Background
Metadata
- Authors
- Meyer-Lindenberg, A., Mervis, C. B., & Faith Berman, K.
- Venue
- Nature Reviews Neuroscience
- Published
- 2006-05
- Volume
- 7
- Issue
- 5
- Pages
- 380-393
- ISSN
- 1471-003X (ISSN-L)
- 1471-0048
- OpenAlex
- W2074408785
- Cited by
- 411
- References
- 184
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 10 · 2023: 11 · 2022: 10 · 2021: 36 · 2020: 11 · 2019: 12 · 2018: 22 · 2017: 22 · 2016: 16 · 2015: 17 · 2014: 21 · 2013: 21 · 2012: 35
- FWCI
- 2.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature reviews. Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke (R01NS035102)
- Topics
- Life Sciences › Neuroscience › Developmental Neuroscience › Williams Syndrome Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- Williams syndrome, chromosome 7q11.23 microdeletion, neurodevelopmental disorders, hypersociability, social behavior, cognitive profile, neural correlates, brain structure, animal models, modularity of mind, brain development
- MeSH terms
- Animals, Behavior, Brain, Cognition, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Social Behavior, Williams Syndrome
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