Cited by 415Williams Syndrome ResearchGenetics and Neurodevelopmental DisordersNeuroendocrine regulation and behavior

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Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour

Meyer-Lindenberg, Andreas, Mervis, Carolyn B., Faith Berman, Karen·2006·Nature Reviews Neuroscience

DOI 10.1038/nrn1906

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Abstract

Williams syndrome, a rare disorder caused by hemizygous microdeletion of about 28 genes on chromosome 7q11.23, has long intrigued neuroscientists with its unique combination of striking behavioural abnormalities, such as hypersociability, and characteristic neurocognitive profile. Williams syndrome, therefore, raises fundamental questions about the neural mechanisms of social behaviour, the modularity of mind and brain development, and provides a privileged setting to understand genetic influences on complex brain functions in a 'bottom-up' way. We review recent advances in uncovering the functional and structural neural substrates of Williams syndrome that provide an emerging understanding of how these are related to dissociable genetic contributions characterized both in special participant populations and animal models.

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Fodor, J. A. (1983) · doi:10.7551/mitpress/4737.001.0001 · Cited by 7,734
Analysis of visual behavior
Ingle, D., Goodale, M. A., & Mansfield, R. J. W. (1982) · The MIT Press eBooks · Cited by 4,118
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
Egan, M. F., Kojima, M., Callicott, J. H., Goldberg, T. E., Kolachana, B. S., Bertolino, A., Zaitsev, E., Gold, B., Goldman, D., Dean, M., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00035-7 · Cited by 3,888
Beyond modularity: a developmental perspective on cognitive science
Karmiloff‐Smith, A. (1993) · Choice Reviews Online · doi:10.5860/choice.30-5872 · Cited by 2,594
The modularity of mind: An essay on faculty psychology. By Jerry A. Fodor. Cambridge, MA: MIT Press, 1983. Pp. ix, 145. Cloth $17.50, paper $8.50.
Matthei, E. H. (1984) · Language · doi:10.2307/413815 · Cited by 2,189
Beyond Modularity
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The functional neuroanatomy of the human orbitofrontal cortex: Evidence from neuroimaging and neuropsychology
KRINGELBACH, M. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.03.006 · Cited by 1,977
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A tension-based theory of morphogenesis and compact wiring in the central nervous system
Essen, D. C. V. (1997) · Nature · doi:10.1038/385313a0 · Cited by 1,668
Cognitive neuroscience of human social behaviour
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Marenco, S. et al. Preliminary diffusion tensor imaging (DTI) observations in 5 individuals with Williams syndrome (WS). Neuroimage 22 (Suppl. 1), M0363 (2004).
Olsen, R. K. et al. Retinotopic mapping of early visual areas in Williams syndrome. Presented at the Human Brain Mapping Meeting 2003 (New York, USA). Neuroimage 19 (Suppl. 1), 1550 (2003).
Nardini, M., Breckenridge, K. E., Eastwood, R. L., Atkinson, J. & Braddick, O. J. Distinct developmental trajectories in three systems for spatial encoding between the ages of 3 and 6 years. Perception S33, 28b (2004).
Lukács, A., Racsmány, M. & Pléh, C. Vocabulary and morphological patterns in Hungarian children with Williams syndrome: a preliminary report. Acta Linguistica Hungarica 48, 243–269 (2001).
Mons, A. W., Wilmowski, W. A. & Detweiler, C. Williams Syndrome: a Highly Musical Species (EO Productions International, 1996).
Gordon, F. E. in Musical Aptitude Profile (Houghton Mifflin, Boston, 1995).
Gordon, F. E. Primary Measures of Music Audiation (G. I. A. Publications, Chicago, 1980).

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Self-citation
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Self-citation
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Authors: Meyer-Lindenberg, A., Mervis, C. B., & Faith Berman, K.
Venue: Nature Reviews Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2006-05
Volume: 7
Issue: 5
Pages: 380-393
ISSN: 1471-003X (ISSN-L)
1471-0048
DOI: 10.1038/nrn1906
OpenAlex: W2074408785
Cited by: 411
References: 184
Citations by year: 2026: 3 · 2025: 5 · 2024: 10 · 2023: 11 · 2022: 10 · 2021: 36 · 2020: 11 · 2019: 12 · 2018: 22 · 2017: 22 · 2016: 16 · 2015: 17 · 2014: 21 · 2013: 21 · 2012: 35
FWCI: 2.23
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature reviews. Neuroscience (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Neurological Disorders and Stroke (R01NS035102)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Williams Syndrome Research
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
Keywords: Williams syndrome, chromosome 7q11.23 microdeletion, neurodevelopmental disorders, hypersociability, social behavior, cognitive profile, neural correlates, brain structure, animal models, modularity of mind, brain development
MeSH terms: Animals, Behavior, Brain, Cognition, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Social Behavior, Williams Syndrome

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Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour

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