Intracellular amyloid-β in Alzheimer's disease

LaFerla, Frank M., Green, Kim N., Oddo, Salvatore·2007·Nature Reviews Neuroscience

DOI 10.1038/nrn2168

Cited by (1,005)

Items 201–300 of 1,005

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Anthony Markham, Rasneer Sonia Bains, P Franklin, Michael Spedding · 2013 · British Journal of Pharmacology
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Choi, Bo-Ryoung, Cho, Woo-Hyun, Kim, Jiyoung, Lee, Hyong Joo, Chung, ChiHye, Jeon, Won Kyung, Han, Jung-Soo · 2014 · Experimental & Molecular Medicine
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Herman Moreno, Eunah Yu, Gustavo F. Pigino, Alejandro Ivan Hernandez, Natalia Kim, Jorge E. Moreira, Mutsuyuki Sugimori, Rodolfó R. Llinás · 2009 · Proceedings of the National Academy of Sciences
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