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Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism

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Neuroligins and neurexins link synaptic function to cognitive disease

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Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

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Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice

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A comparison of machine learning methods for quantifying self-grooming behavior in mice

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Gestational hypothyroxinemia induces ASD-like phenotypes in behavior, proinflammatory markers, and glutamatergic protein expression in mouse offspring of both sexes

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Sex differences in the social motivation of rats: Insights from social operant conditioning, behavioural economics, and video tracking

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Targeting S100A9 attenuates social dysfunction by modulating neuroinflammation and myelination in a mouse model of autism

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Methodological considerations in the use of Noldus EthoVision XT video tracking of children with autism in multi-site studies

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Chronic consumption of a high linoleic acid diet during pregnancy, lactation and post-weaning period increases depression-like behavior in male, but not female offspring

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Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

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Autophosphorylation of αCaMKII affects social interactions in mice

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BK channel blocker paxilline attenuates thalidomide-caused synaptic and cognitive dysfunctions in mice

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Cyclin D2-knock-out mice with attenuated dentate gyrus neurogenesis have robust deficits in long-term memory formation

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The clock gene Period1 regulates innate routine behaviour in mice

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Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice

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Mice with Dab1 or Vldlr insufficiency exhibit abnormal neonatal vocalization patterns

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New approaches to quantify social development in rhesus macaques (Macaca mulatta): Integrating eye tracking with traditional assessments of social behavior

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Connecting Genotype with Behavioral Phenotype in Mouse Models of Autism Associated with PTEN MutationsPreprint

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Sex Differences in Mouse Models of Autism Spectrum Disorders: Their Potential to Uncover the Impact of Brain Sexual Differentiation on Gender Bias

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Developmental exposure to the Fox River PCB mixture modulates behavior in juvenile mice

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The Role of Thioredoxin System in Shank3 Mouse Model of Autism

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Hyperexcitability and translational phenotypes in a preclinical mouse model of SYNGAP1-related intellectual disability

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A blueprint for research on Shankopathies: A view from research on autism spectrum disorder

Carbonetto, S. (2013) · Developmental Neurobiology · doi:10.1002/dneu.22150 · Cited by 13

Oxytocin in the regulation of social behaviours in medial amygdala‐lesioned mice via the inhibition of the extracellular signal‐regulated kinase signalling pathway

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Construct Validity and Cross Validity of a Test Battery Modeling Autism Spectrum Disorder (ASD) in Mice

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Inhibition of striatal-enriched protein tyrosine phosphatase (STEP) activity reverses behavioral deficits in a rodent model of autism

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Functional MHCI deficiency induces ADHD-like symptoms with increased dopamine D1 receptor expression

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Neuroligins in neurodevelopmental conditions: how mouse models ofde novomutations can help us link synaptic function to social behavior

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Genomic Strategies for Understanding the Pathophysiology of Autism Spectrum Disorder

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Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder

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Acute Stress Modulates Social Approach and Social Maintenance in Adult Zebrafish

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Animal models of autism with a particular focus on the neural basis of changes in social behaviour: An update article

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Brain enhancer activities at the gene-poor 5p14.1 autism-associated locus

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ErbB signaling antagonist ameliorates behavioral deficit induced by phencyclidine (PCP) in mice, without affecting metabolic syndrome markers

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Behavioral Assays in the Study of Olfaction: A Practical Guide

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Sex-Dependent Motor Deficit and Increased Anxiety-Like States in Mice Lacking Autism-Associated Gene Slit3

Park, S. M., Plachez, C., & Huang, S. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00261 · Cited by 13

Behavioral impairments in infant and adult mouse offspring exposed to 2,3,7,8-tetrabromodibenzofuran in utero and via lactation

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Juvenile high–fat diet–induced senescent glial cells in the medial prefrontal cortex drives neuropsychiatric behavioral abnormalities in mice

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Proximity as a predictor of social behavior in rats

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Rubber tail illusion is weakened in Ca2+-dependent activator protein for secretion 2 (Caps2)-knockout mice

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Single cell 3’UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autismPreprint

Göpferich, M., George, N. O., Domingo-Muelas, A., Bizyn, A., Pascual, R., Fijałkowska, D., Kalamakis, G., Müller, U., Krijgsveld, J., Méndez, R., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.08.12.247627 · Cited by 13

Zmiz1 is a novel regulator of brain development associated with autism and intellectual disability

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Prenatal immune activation in mice induces long-term alterations in brain mitochondrial function

Gasser, E. M. S., Schaer, R., Mueller, F. S., Bernhardt, A. C., Lin, H.-Y., Arias‐Reyes, C., & Weber‐Stadlbauer, U. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03010-x · Cited by 12

S-ketamine exposure in early postnatal period induces social deficit mediated by excessive microglial synaptic pruning

Zhong, H., Xue, R., Han, Y., Liu, L., Zhao, J., Cai, M., Wang, S., Wei, P., Zhao, G., & Dong, H. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-02949-7 · Cited by 12

Alterations in the ultrasonic vocalization sequences in pups of an autism spectrum disorder mouse model: A longitudinal study over age and sex

Agarwalla, S., Yuvarani, M., & Bandyopadhyay, S. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111372 · Cited by 12

Oxytocin signaling regulates maternally directed behavior during early life

Zelmanoff, D. D., Bornstein, R., Kaufman, M., Dine, J., Wietek, J., Litvin, A., Abraham, S., Cohen, S., Atzmon, A., Porat, I., et al. (2025) · Science · doi:10.1126/science.ado5609 · Cited by 13

NGL-1/LRRC4C-Mutant Mice Display Hyperactivity and Anxiolytic-Like Behavior Associated With Widespread Suppression of Neuronal Activity

Choi, Y., Park, H., Kang, S., Jung, H., Kweon, H., Kim, S., Choi, I., Lee, S. Y., Choi, Y., Lee, S., et al. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00250 · Cited by 12

3-Aminobenzamide alleviates elevated DNA damage and DNA methylation in a BTBR T+Itpr3/J mouse model of autism by enhancing repair gene expression

Attia, S. M., Ahmad, S. F., Nadeem, A., Attia, M. S. M., Ansari, M. A., Sobeai, H. M. A., Al‐Mazroua, H. A., Alasmari, A. F., & Bakheet, S. A. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173057 · Cited by 12

Sex-Specific Social Behavior and Amygdala Proteomic Deficits in Foxp2+/− Mutant Mice

Herrero, M. J., Wang, L., Hernandez‐Pineda, D., Banerjee, P., Matos, H. Y., Goodrich, M., Panigrahi, A. K., Smith, N., & Corbin, J. G. (2021) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.706079 · Cited by 12

Size anomaly and alteration of GABAergic enzymes expressions in cerebellum of a valproic acid mouse model of autism

Ma, S. Y., & Kwan, K. M. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.113896 · Cited by 12

Reversibility and therapeutic development for neurodevelopmental disorders, insights from genetic animal models

Megagiannis, P., Suresh, R., Rouleau, G. A., & Zhou, Y. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114562 · Cited by 12

Genetic ablation of metabotropic glutamate receptor 5 in rats results in an autism-like behavioral phenotype

Eshraghi, A. A., Memis, I., Wang, F., White, I., Furar, E., Mittal, J., Moosa, M., Atkins, C. M., & Mittal, R. (2022) · PLoS ONE · doi:10.1371/journal.pone.0275937 · Cited by 12

Auts2 regulated autism-like behavior, glucose metabolism and oxidative stress in mice

Liu, M., Chen, Y., Sun, M., Du, Y., Bai, Y., Lei, G., Zhang, C., Zhang, M., Zhang, Y., Xi, C., et al. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114298 · Cited by 12

Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1-KO mouse models

Sharghi, S., Flunkert, S., Daurer, M., Rabl, R., Chagnaud, B. P., Leopoldo, M., Lacivita, E., Hutter‐Paier, B., & Prokesch, M. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1087788 · Cited by 12

microRNA as a Maternal Marker for Prenatal Stress-Associated ASD, Evidence from a Murine Model

Woo, T., King, C., Ahmed, N. I., Cordes, M., Nistala, S., Will, M. J., Bloomer, C., Kibiryeva, N., Rivera, R. M., Talebizadeh, Z., et al. (2023) · Journal of Personalized Medicine · doi:10.3390/jpm13091412 · Cited by 12

Unweaving the Autism Spectrum

Lord, C. (2011) · Cell · doi:10.1016/j.cell.2011.09.017 · Cited by 12

Mouse Behavior and Models for Autism Spectrum Disorders

Ricceri, L., Michetti, C., & Scattoni, M. L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800109-7.00017-0 · Cited by 13

Heterozygous mutation of sonic hedgehog receptor (Ptch1) drives cerebellar overgrowth and sex-specifically alters hippocampal and cortical layer structure, activity, and social behavior in female mice

Jackson, T. W., Bendfeldt, G. A., Beam, K. A., Rock, K. D., & Belcher, S. M. (2020) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2020.106866 · Cited by 12

Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice

Martin‐Kenny, N., & Bérubé, N. G. (2020) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-020-09319-0 · Cited by 12

Examining the effect of chronic intranasal oxytocin administration on the neuroanatomy and behavior of three autism-related mouse models

Lindenmaier, Z., Ellegood, J., Stuive, M., Easson, K., Yee, Y., Fernandes, D., Foster, J. A., Anagnostou, E. A., & Lerch, J. P. (2022) · NeuroImage · doi:10.1016/j.neuroimage.2022.119243 · Cited by 12

Blocking the ErbB pathway during adolescence affects the induction of anxiety-like behavior in young adult maternal immune activation offspring

Abu-Ata, S., Shukha, O. N., Awad-Igbaria, Y., Ginat, K., Palzur, E., Golani, I., & Shamir, A. (2022) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2022.173497 · Cited by 12

Variable behavior and repeated learning in two mouse strains: Developmental and genetic contributions

Arnold, M. A., & Newland, M. C. (2018) · Behavioural Processes · doi:10.1016/j.beproc.2018.06.007 · Cited by 12

Deletion of BDNF in Pax2 Lineage-Derived Interneuron Precursors in the Hindbrain Hampers the Proportion of Excitation/Inhibition, Learning, and Behavior

Eckert, P., Marchetta, P., Manthey, M., Walter, M. H., Jovanović, S., Savitska, D., Singer, W., Jacob, M. H., Rüttiger, L., Schimmang, T., et al. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.642679 · Cited by 13

Delayed parenthood and its influence on offspring health: what have we learned from the mouse model

Zacchini, F., Sampino, S., Ziętek, M. M., & Chan, A. B. (2021) · Biology of Reproduction · doi:10.1093/biolre/ioab202 · Cited by 12

Early estradiol exposure masculinizes disease‐relevant behaviors in female mice

Seiffe, A., Ramirez, M. F., Barrios, C. D., Albarrán, M. M., & Depino, A. M. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15130 · Cited by 11

Deficiency of FRMD5 results in neurodevelopmental dysfunction and autistic-like behavior in mice

Lyu, T., Ma, J., Zhang, X.-Y., Xie, G., Liu, C., Du, J., Xu, Y.-N., Yang, D.-C., Cen, C., Wang, M.-Y., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02407-w · Cited by 11

Mapping the Behavioral Signatures of Shank3b Mice in Both Sexes

Liu, J., Ye, J., Ji, C., Ren, W., He, Y., Xu, F., & Wang, L. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01237-8 · Cited by 11

Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters

Pantouli, F., Pujol, C., Derieux, C., Fonteneau, M., Pellissier, L. P., MARSOL, C., Karpenko, J., Bonnet, D., Hibert, M., Bailey, A., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01915-1 · Cited by 11

Deep learning-based scoring method of the three-chamber social behaviour test in a mouse model of alcohol intoxication. A comparative analysis of DeepLabCut, commercial automatic tracking and manual scoring

Zahran, M. A., Mañas-Ojeda, A., Navarro-Sánchez, M., Castillo-Gómez, E., & Olucha-Bordonau, F. E. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e36352 · Cited by 11

Mountable miniature microphones to identify and assign mouse ultrasonic vocalizations

Waidmann, E. N., Yang, V. H. Y., Luo, E., Doyle, W. C., & Jarvis, E. D. (2025) · Cell Reports Methods · doi:10.1016/j.crmeth.2025.101081 · Cited by 11

Autism spectrum disorder model mice: Focus on copy number variation and epigenetics

Nakai, N., Otsuka, S., Myung, J., & Takumi, T. (2015) · Science China Life Sciences · doi:10.1007/s11427-015-4891-7 · Cited by 11

Genetic models of schizophrenia and related psychotic disorders: progress and pitfalls across the methodological “minefield”

O’Tuathaigh, C. M. P., Moran, P. M., & Waddington, J. L. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1652-4 · Cited by 11

Computational Analysis of Neonatal Mouse Ultrasonic Vocalization

Broin, P. Ó., Beckert, M. V., Takahashi, T., Izumi, T., Ye, K. Q., Kang, G., Pouso, P., Topolski, M. A., Peña, J. L., & Hiroi, N. (2018) · Current Protocols in Mouse Biology · doi:10.1002/cpmo.46 · Cited by 11

Role of melatonin in autism spectrum disorders in a male murine transgenic model: Study in the prefrontal cortex

Borsani, E., Bonomini, F., Bonini, S. A., Premoli, M., Maccarinelli, G., Giugno, L., Mastinu, A., Aria, F., Memo, M., & Rezzani, R. (2022) · Journal of Neuroscience Research · doi:10.1002/jnr.24997 · Cited by 12

The CaV1.2 G406R mutation decreases synaptic inhibition and alters L-type Ca2+ channel-dependent LTP at hippocampal synapses in a mouse model of Timothy Syndrome

Sanderson, J. L., Freund, R. K., Castano, A. M., Benke, T. A., & Dell’Acqua, M. L. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109271 · Cited by 11

Deep-Learning-Based Analysis Reveals a Social Behavior Deficit in Mice Exposed Prenatally to Nicotine

Zhou, M., Qiu, W., Ohashi, N., Sun, L., Wronski, M., Kouyama-Suzuki, E., Shirai, Y., Yanagawa, T., Mori, T., & Tabuchi, K. (2024) · Cells · doi:10.3390/cells13030275 · Cited by 11

Contribución genética, ambiental y epigenética en la susceptibilidad a los trastornos del espectro autista

Díaz‐Anzaldúa, A., & Martínez, A. D. (2013) · Revista de Neurología · doi:10.33588/rn.5712.2013072 · Cited by 11

Reduced sulfate plasma concentrations in the BTBR T+tf/J mouse model of autism

Corley, M. J., Meyza, K. Z., Blanchard, D. C., & Blanchard, R. J. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.04.010 · Cited by 11

Genetic influences of autism candidate genes on circuit wiring and olfactory decoding

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