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Cited by 366

The DOI matches its Crossref record; 133 of the 133 references it cites were found in a registry or an index.

Temporal fate specification and neural progenitor competence during development

Open access
Kohwi, Minoree, Doe, Chris Q.·2013·Nature Reviews Neuroscience

Abstract

The vast diversity of neurons and glia of the CNS is generated from a small, heterogeneous population of progenitors that undergo transcriptional changes during development to sequentially specify distinct cell fates. Guided by cell-intrinsic and -extrinsic cues, invertebrate and mammalian neural progenitors carefully regulate when and how many of each cell type is produced, enabling the formation of functional neural circuits. Emerging evidence indicates that neural progenitors also undergo changes in global chromatin architecture, thereby restricting when a particular cell type can be generated. Studies of temporal-identity specification and progenitor competence can provide insight into how we could use neural progenitors to more effectively generate specific cell types for brain repair.

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Metadata

Authors
Kohwi, M., & Doe, C. Q.
Venue
Nature Reviews Neuroscience
Published
2013-11-20
Volume
14
Issue
12
Pages
823-838
ISSN
  • 1471-003X (ISSN-L)
  • 1471-0048
OpenAlex
W2615767183
Cited by
366
References
133
FWCI
1.95
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Temporal fate specification and neural progenitor competence during development. https://app.cochat.ai/papers/10.1038/nrn3618
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Kohwi, M., & Doe, C. Q. (2013). Temporal fate specification and neural progenitor competence during development. Nature Reviews Neuroscience. https://doi.org/10.1038/nrn3618

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.