Spreading of pathology in neurodegenerative diseases: a focus on human studies

Brettschneider, Johannes, Tredici, Kelly Del, Lee, Virginia M.-Y., Trojanowski, John Q.·2015·Nature Reviews Neuroscience

DOI 10.1038/nrn3887

Cited by (797)

Items 201–300 of 797

Roles for the adaptive immune system in Parkinson’s and Alzheimer’s diseases
Cecilia S. Lindestam Arlehamn, Francesca Garretti, David L. Sulzer, Alessandro Sette · 2019 · Current Opinion in Immunology
α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome
Xiaohong Wang, Jinghong Chi, Di Huang, Li Ding, Xiaojing Zhao, Lai Jiang, Yang Yu, Feng Gao · 2019 · Experimental and Therapeutic Medicine
3D-visualization of amyloid-β oligomer interactions with lipid membranes by cryo-electron tomography
Yao Tian, Ruina Liang, Amit Kumar, Piotr Szwedziak, John H. Viles · 2021 · Chemical Science
Brain Somatic Mutation in Aging and Alzheimer's Disease
Michael B. Miller, Hannah Reed, Christopher A. Walsh · 2021 · Annual Review of Genomics and Human Genetics
Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease
Jacob W. Vogel, Yasser Iturria‐Medina, Olof T. Strandberg, Ruben A Smith, Alan Charles Evans, Oskar Hansson, for the Alzheimer’s Disease Neuroimaging Initiative, and the Swedish BioFinder Study · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
Transcranial Ultrasound Stimulation Suppresses Neuroinflammation in a Chronic Mouse Model of Parkinson's Disease
Hui Zhou, Long Meng, Xiangxiang Xia, Zhengrong Lin, Wei Zhou, Na Pang, Tianyuan Bian, Tifei Yuan, Lili Niu, Hairong Zheng · 2021 · IEEE Transactions on Biomedical Engineering
Progression of Seed‐Induced A β Deposition within the Limbic Connectome
Lan Ye, Tsuyoshi Hamaguchi, Sarah K. Fritschi, Yvonne S. Eisele, Ulrike Obermüller, Mathias Jucker, Lary C. Walker · 2015 · Brain Pathology
Prion-like p53 Amyloids in Cancer
Ambuja Navalkar, Saikat Ghosh, Satyaprakash Pandey, Ajoy Paul, Debalina Datta, Samir Kumar Maji · 2019 · Biochemistry
Dementia with Lewy bodies: association of Alzheimer pathology with functional connectivity networks
Julia Schumacher, Jeffrey L. Gunter, Scott A. Przybelski, David Thomas Jones, Jonathan Graff‐Radford, Rodolfo Savica, Christopher G. Schwarz, Matthew L. Senjem, Clifford R. Jack, Val J. Lowe et al. · 2021 · Brain
Microglial and Neuronal TDP-43 Pathology in Anti-IgLON5-Related Tauopathy
Annachiara Cagnin, Sara Mariotto, Michele Fiorini, Marina Gaule, Nicola Bonetto, Matteo Tagliapietra, Emanuele Buratti, Gianluigi Zanusso, Sérgio Ferrari, Salvatore Monaco · 2017 · Journal of Alzheimer s Disease
Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases
Natura Myeku, Karen Duff · 2017 · Trends in Molecular Medicine
Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration
James D. Alibhai, Richard A. Blanco, Marcelo A. Barria, Pedro Piccardo, Byron W. Caughey, Victor Hugh Perry, Tom C. Freeman, Jean C. Manson · 2016 · PLoS Biology
MFSC: Multi-voting based feature selection for classification of Golgi proteins by adopting the general form of Chou's PseAAC components
Jamal Ahmad, Maqsood Hayat · 2018 · Journal of Theoretical Biology
Cognitive heterogeneity in Parkinson’s disease: A mechanistic view
Marc Carceles‐Cordon, Dan Weintraub, Alice S. Chen‐Plotkin · 2023 · Neuron
Somatic mutations in neurons during aging and neurodegeneration
Bert M. Verheijen, Marc Vermulst, Fred W. van Leeuwen · 2018 · Acta Neuropathologica
Microorganisms’ Footprint in Neurodegenerative Diseases
Mona Dehhaghi, Hamed Kazemi Shariat Panahi, Gilles J. Guillemin · 2018 · Frontiers in Cellular Neuroscience
Modeling neurodegenerative diseases with cerebral organoids and other three-dimensional culture systems: focus on Alzheimer’s disease
Lalitha Venkataraman, Summer Rose Fair, Craig A. McElroy, Mark E. Hester, Hongjun Fu · 2020 · Stem Cell Reviews and Reports
Pomegranate: A promising avenue against the most common chronic diseases and their associated risk factors (Review)
Alessandro Lavoro, Luca Falzone, Giuseppe Gattuso, Rossella Salemi, Giovanni Cultrera, Gian Marco Leone, Giuseppa Scandurra, Saverio Candido, Massimo Libra · 2021 · International Journal of Functional Nutrition
Spatial Relationships between Molecular Pathology and Neurodegeneration in the Alzheimer’s Disease Continuum
Leonardo Iaccarino, Renaud La Joie, Lauren Edwards, Amelia Strom, Daniel R. Schonhaut, Rik Ossenkoppele, Julie Q. Pham, Taylor J. Mellinger, Mustafa Janabi, Suzanne L. Baker et al. · 2020 · Cerebral Cortex
Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice
Xiaoguang Li, Zhihao Wang, Lu Tan, Yali Wang, Chengbiao Lu, Rongxiang Chen, Shujuan Zhang, Yuan Gao, Yanchao Liu, Yaling Yin et al. · 2017 · Molecular Therapy
Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation
Liyan Hou, Cong Zhang, Ke Wang, Xiaofang Liu, Hongwei Wang, Yuning Che, Fuqiang Sun, Xueying Zhou, Xiulan Zhao, Qingshan Wang · 2017 · Toxicology
An Efficient Procedure for Removal and Inactivation of Alpha-Synuclein Assemblies from Laboratory Materials
Bousset, Luc, Brundin, Patrik, Böckmann, Anja, Meier, Beat, Melki, Ronald · 2016 · Journal of Parkinson’s Disease
Long-term episodic memory decline is associated with olfactory deficits only in carriers of ApoE-є4
Jonas Olofsson, Maria Josefsson, Ingrid Ekström, Donald A. Wilson, Lars H Nyberg, Steven Nordin, Annelie Nordin Adolfsson, Rolf Adolfsson, Lars‐Göran Nilsson, Maria U. Larsson · 2016 · Neuropsychologia
Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging
Tomohiro Ishii, Emiko Kawakami, Kentaro Endo, Hidemi Misawa, Kazuhiko Watabe · 2017 · PLoS ONE
Untangling the Tauopathy for Alzheimer’s disease and parkinsonism
Hui-Yun Chang, Tzu‐Kang Sang, Ann‐Shyn Chiang · 2018 · Journal of Biomedical Science
Gray matter T1‐w/T2‐w ratios are higher in Alzheimer's disease
Wiesje Pelkmans, Ellen Dicks, Frederik Barkhof, Hugo Vrenken, Philip Scheltens, Wiesje M. van der Flier, Betty Marije Tijms · 2019 · Human Brain Mapping
Role of Medicinal Plants against Neurodegenerative Diseases
Ritika Luthra, Arpita Roy · 2021 · Current Pharmaceutical Biotechnology
On the Structural Diversity and Individuality of Polymorphic Amyloid Protein Assemblies
Liisa Lutter, Liam D. Aubrey, Wei‐Feng Xue · 2021 · Journal of Molecular Biology
Molecular Dissection of TDP-43 as a Leading Cause of ALS/FTLD
Yoshitaka Tamaki, Makoto Urushitani · 2022 · International Journal of Molecular Sciences
Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer’s disease
Jangampalli Adi Pradeepkiran, Arubala P. Reddy, P. Hemachandra Reddy · 2018 · Drug Discovery Today
Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease
Chiarini, Anna, Armato, Ubaldo, Liu, Daisong, Dal Prà, Ilaria · 2016 · Frontiers in Physiology
Neural synchronization in Alzheimer's disease
Liviu Aron, Bruce A. Yankner · 2016 · Nature
Four-Repeat Tauopathies: Current Management and Future Treatments
Lawren A. VandeVrede, Peter Alexander Ljubenkov, Julio C. Rojas, Ariane E. Welch, Adam L. Boxer · 2020 · Neurotherapeutics
Functional roles of the microbiota-gut-brain axis in Alzheimer’s disease: Implications of gut microbiota-targeted therapy
Si-Ran Zhong, Qi Kuang, Fan Zhang, Ben Chen, Zhen-Guo Zhong · 2021 · Translational Neuroscience
Prion‐like propagation as a pathogenic principle in frontotemporal dementia
Eva‐Maria Hock, Magdalini Polymenidou · 2016 · Journal of Neurochemistry
Proteomic analysis of protein homeostasis and aggregation
Ewa Laskowska, Dorota Kuczyńska‐Wiśnik, Barbara Lipińska · 2018 · Journal of Proteomics
Salience Network Atrophy Links Neuron Type-Specific Pathobiology to Loss of Empathy in Frontotemporal Dementia
Lorenzo Pasquini, Alissa L. Nana, Gianina Toller, Jesse A. Brown, Jersey Deng, Adam M. Staffaroni, Eun Joo Kim, Jihye Hwang, Libo Li, Yongsoon Park et al. · 2020 · Cerebral Cortex
Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration
Chang, Yung-Heng, Dubnau, Josh · 2023 · Nature Communications
Cortical brain volume abnormalities associated with few or multiple neuropsychiatric symptoms in Alzheimer’s disease
Lyssandra dos Santos Tascone, Martha E. Payne, James R. MacFall, Dionı́sio Azevedo, Cláudio Campi de Castro, David C. Steffens, Geraldo F. Busatto, Cássio M. C. Bottino · 2017 · PLoS ONE
Exosomes as Emerging Biomarker Tools in Neurodegenerative and Neuropsychiatric Disorders—A Proteomics Perspective
Boby Mathew, Mohammad Shahid Mansuri, Kenneth R. Williams, Angus Clark Nairn · 2021 · Brain Sciences
The heterogeneity of microglial activation and its epigenetic and non-coding RNA regulations in the immunopathogenesis of neurodegenerative diseases
Chaoyi Li, Jie Ren, Mengfei Zhang, Huakun Wang, Yi Fang, Junjiao Wu, Yu Tang · 2022 · Cellular and Molecular Life Sciences
The evolving landscape of Alzheimer’s disease therapy: From Aβ to tau
Jean‐Philippe Courade, Henrik Zetterberg, Günter U. Höglinger, Ilse Dewachter · 2025 · Cell
O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein
Paul M. Levine, Cesar A. De Leon, Ana Galesic, Aaron T. Balana, Nicholas P. Marotta, Yuka E. Lewis, Matthew R. Pratt · 2017 · Bioorganic & Medicinal Chemistry
Mitochondrial ROS-mediated post-transcriptional regulation of α-synuclein through miR-7 and miR-153
Goun Je, Yoon‐Seong Kim · 2017 · Neuroscience Letters
Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease
Sivaprakasam R. Saroja, Abhijeet Sharma, Patrick R. Hof, Ana C. Pereira · 2021 · Alzheimer s & Dementia
Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies
Almudena Fuster-Matanzo, Félix Hernández, Jesús Ávila · 2018 · International Journal of Molecular Sciences
The road ahead in clinical network neuroscience
Linda Douw, Edwin van Dellen, Alida A. Gouw, Alessandra Griffa, Willem de Haan, Martijn P. van den Heuvel, Arjan Hillebrand, Piet Van Mieghem, Ida A. Nissen, Willem M. Otte et al. · 2019 · Network Neuroscience
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
Mingming Xu, Philip Ryan, Santosh Rudrawar, Ronald J. Quinn, Haiyan Zhang, George D. Mellick · 2019 · Acta Pharmacologica Sinica
Near‐Infrared Afterglow Semiconducting Nano‐Polycomplexes for the Multiplex Differentiation of Cancer Exosomes
Yan Lyu, Dong Mei Cui, Jiaguo Huang, Wenxuan Fan, Yansong Miao, Kanyi Pu · 2019 · Angewandte Chemie
Cannabinoid CB2 Receptors in Neurodegenerative Proteinopathies: New Insights and Therapeutic Potential
Barbara Vuić, Tina Milos, Lucija Tudor, Marcela Konjevod, Matea Nikolac Perković, Maja Jazvinšćak Jembrek, Gordana Nedić Erjavec, Dubravka Švob Štrac · 2022 · Biomedicines
Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation
Nadia El Mammeri, Aurelio James Dregni, Pu Duan, Mei Hong · 2024 · Proceedings of the National Academy of Sciences
Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
Katherine H. Franks, Meng Inn Chuah, Anna Elizabeth King, James Clement Vickers · 2015 · Frontiers in Aging Neuroscience
Exploring the power of yeast to model aging and age-related neurodegenerative disorders
Ana Vanessa Oliveira, Rita Vilaça, Cláudia Nunes dos Santos, Vítor Costa, Regina Menezes · 2016 · Biogerontology
Age- and sex-specific modifiable risk factor profiles of dementia: evidence from the UK Biobank
Hui Chen, Yaying Cao, Yuan Ma, Weili Xu, Geng Zong, Changzheng Yuan · 2023 · European Journal of Epidemiology
Dysregulation of extracellular potassium distinguishes healthy ageing from neurodegeneration
Fengfei Ding, Qian Sun, Carter Long, Rune Nguyen Rasmussen, Sisi Peng, Qiwu Xu, Ning Kang, Wei Song, Pia Weikop, Steven A. Goldman et al. · 2024 · Brain
Fast progressive lower motor neuron disease is an ALS variant: A two-centre tract of interest-based MRI data analysis
Hans‐Peter Müller, Federica Agosta, Nilo Riva, Edoardo Gioele Spinelli, Gıancarlo Comı, Albert Christian Ludolph, Massimo Filippi, Jan Kassubek · 2017 · NeuroImage Clinical
Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain
Amber Tariq, JiaBei Lin, Megan M. Noll, Mariana P. Torrente, Korrie L. Mack, Oscar A. Hernandez Murillo, Meredith E. Jackrel, James Shorter · 2018 · FEMS Yeast Research
Converging Patterns of α-Synuclein Pathology in Multiple System Atrophy
Johannes Brettschneider, EunRan R. Suh, John L. Robinson, Lubin Fang, Edward B. Lee, David John Irwin, Murray Grossman, Vivianna M. Van Deerlin, Virginia M.‐Y. Lee, John Q. Trojanowski · 2018 · Journal of Neuropathology & Experimental Neurology
Systemic peptide mediated delivery of an siRNA targeting α-syn in the CNS ameliorates the neurodegenerative process in a transgenic model of Lewy body disease
Brian J. Spencer, Ivy Trinh, Edward M. Rockenstein, Michael Mante, Jazmin B. Florio, Anthony Adame, Omar M. A. El‐Agnaf, Changyoun Kim, Eliezer Masliah, Robert A. Rissman · 2019 · Neurobiology of Disease
Mechanisms of Neuroprotective Effects of Peptides Derived from Natural Materials and Their Production and Assessment
Seung Yun Lee, Sun Jin Hur · 2019 · Comprehensive Reviews in Food Science and Food Safety
Whole‐brain snapshot CEST imaging at 7 T using 3D‐EPI
Suzan Akbey, Philipp Ehses, Rüdiger Stirnberg, Moritz Zaiß, Tony Stöcker · 2019 · Magnetic Resonance in Medicine
The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology
Dylan Mah, Jing Zhao, Xinyue Liu, Fuming Zhang, Jian Liu, Lianchun Wang, Robert J. Linhardt, Chunyu Wang · 2021 · Frontiers in Molecular Biosciences
Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?
Haibo Wang, Prakash Dharmalingam, Velmarini Vasquez, Joy Mitra, Istvan R. Boldogh, K. S. Jagannatha Rao, Thomas A. Kent, SANKAR P. MITRA, Muralidhar L. Hegde · 2016 · Mechanisms of Ageing and Development
E46K α-synuclein pathological mutation causes cell-autonomous toxicity without altering protein turnover or aggregation
Ignacio Íñigo-Marco, Miguel Valencia, Laura Larrea, Ricardo Bugallo, Mikel Martínez-Goikoetxea, Iker Zuriguel, Montserrat Arrasate · 2017 · Proceedings of the National Academy of Sciences
Are comorbidities compatible with a molecular pathological classification of neurodegenerative diseases?
Gábor Géza Kovács · 2019 · Current Opinion in Neurology
Design, synthesis and evaluation of flurbiprofen-clioquinol hybrids as multitarget-directed ligands against Alzheimer’s disease
Ziyi Yang, Qing Song, Zhongcheng Cao, Guangjun Yu, Zhuoling Liu, Zhenghuai Tan, Yong Deng · 2020 · Bioorganic & Medicinal Chemistry
A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions
Siân L. Baker, Jürgen Götz · 2016 · Acta Neuropathologica Communications
Epigenetic signature in neural plasticity: the journey so far and journey ahead
Nayak, Madhusmita, Das, Diptimayee, Pradhan, Jyotsnarani, Ahmed, R.G., Laureano-Melo, Roberto, Dandapat, Jagneshwar · 2022 · Heliyon
A critical review of the prion hypothesis of human synucleinopathies
Gültekin Tamgüney, Amos D. Korczyn · 2017 · Cell and Tissue Research
Endoplasmic reticulum stress induces spatial memory deficits by activating GSK ‐3
Lin Li, Jie Cao, Shusheng Yang, Zhengqi Fu, Peng Hui Zeng, Jiang Chu, Lin‐Na Ning, Teng Zhang, Yan Shi, Qing Tian et al. · 2018 · Journal of Cellular and Molecular Medicine
Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders
Sumaira Hanif, Pir Muhammad, Zheng Niu, Muhammad Ismail, Marco Morsch, Xiaoju Zhang, Mingqiang Li, Bingyang Shi · 2021 · Advanced NanoBiomed Research
Caenorhabditis elegans: A transgenic model for studying age-associated neurodegenerative diseases
Nisha Rani, Mohammad Mumtaz Alam, Azfar Jamal, Usama Bin Ghaffar, Suhel Parvez · 2023 · Ageing Research Reviews
A Novel Feature Extraction Method with Feature Selection to Identify Golgi-Resident Protein Types from Imbalanced Data
Runtao Yang, Chengjin Zhang, Rui Gao, Lína Zhang · 2016 · International Journal of Molecular Sciences
The impact of indigenous microbes on Parkinson's disease
Timothy Robert Sampson · 2019 · Neurobiology of Disease
Nuclear Transport Deficits in Tau-Related Neurodegenerative Diseases
Lisa Diez, Susanne Wegmann · 2020 · Frontiers in Neurology
S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD
ELAINE C. PIRIE, Chang-ki Oh, Xu Zhang, Xuemei Han, Piotr Cieplak, Henry R. Scott, Amanda K. Deal, Swagata Ghatak, Fernando J. Martinez, Gene Wei-Ming Yeo et al. · 2021 · Proceedings of the National Academy of Sciences
Phosphorylated tau targeted small-molecule PROTACs for the treatment of Alzheimer's disease and tauopathies
Jangampalli Adi Pradeepkiran, P. Hemachandra Reddy · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Advances in Proteasome Enhancement by Small Molecules
Dare E. George, Jetze J. Tepe · 2021 · Biomolecules
VCP suppresses proteopathic seeding in neurons
Jiang Zhu, Sara K. Pittman, Dhruva D. Dhavale, Rachel L. French, Jessica N. Patterson, Mohamed Salman Kaleelurrrahuman, Yuanzi Sun, Jaime Vaquer‐Alicea, Gianna Maggiore, Christoph Stephan Clemen et al. · 2022 · Molecular Neurodegeneration
Targeting tau only extracellularly is likely to be less efficacious than targeting it both intra- and extracellularly
Erin E. Congdon, Yixiang Jiang, Einar M. Sigurdsson · 2021 · Seminars in Cell and Developmental Biology
Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer’s disease
Sadhana Ravikumar, Amanda E Denning, Sydney Lim, Eunice P. Chung, Niyousha Sadeghpour, Ranjit Ittyerah, Laura E.M. Wisse, Sandhitsu R. Das, Long Xie, John L. Robinson et al. · 2024 · Nature Communications
Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes
Stefania Anna Mari, Susanne Wegmann, Katharina Tepper, Bradley T. Hyman, Eva‐Maria Mandelkow, Eckhard Mandelkow�, Daniel J. Müller · 2018 · Nano Letters
Single cell transcriptomic profiling of a neuron-astrocyte assembloid tauopathy model
Hannah Rickner, Lulu Jiang, Rui Hong, Nicholas K. O’Neill, Chromewell A. Mojica, Benjamin J. Snyder, Lushuang Zhang, Dipan Shaw, Maria Medalla, Benjamin L. Wolozin et al. · 2022 · Nature Communications
Regional vulnerability and spreading of hyperphosphorylated tau in seeded mouse brain
Detrez, Jan R., Maurin, Hervé, Van Kolen, Kristof, Willems, Roland, Colombelli, Julien, Lechat, Benoit, Roucourt, Bart, Van Leuven, Fred, Baatout, Sarah, Larsen, Peter et al. · 2019 · Neurobiology of Disease
CSF biomarkers in neurodegenerative and vascular dementias
Franc Llorens, Matthias Schmitz, Isidró Ferrer, Inga Zerr · 2016 · Progress in Neurobiology
Probiotics and the microbiota-gut-brain axis in neurodegeneration: Beneficial effects and mechanistic insights
Fatemeh Taghizadeh Ghassab, Fatemeh Shamlou Mahmoudi, Reyhaneh Taheri Tinjani, Armitasadat Emami Meibodi, Mohammad Reza Zali, Abbas Yadegar · 2024 · Life Sciences
Appearance of annular ring-like intermediates during amyloid fibril formation from human serum albumin
Shruti Arya, Arpana Kumari, Vijit Dalal, Mily Bhattacharya, Samrat Mukhopadhyay · 2015 · Physical Chemistry Chemical Physics
The Pathoconnectivity Profile of Alzheimer’s Disease: A Morphometric Coalteration Network Analysis
Jordi Manuello, Andrea Nani, Enrico Premi, Barbara Borroni, Tommaso Costa, Karina Tatu, Donato Liloia, Sergio Duca, Franco Cauda · 2018 · Frontiers in Neurology
RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction
Petar Stefanov Kovachev, Mariana P. B. Gomes, Yraima Cordeiro, Natalia Ferreira, Leticia P. Felix Valadão, Lucas M. Ascari, Luciana Pereira Rangel, Jerson Lima Silva, Suparna Sanyal · 2019 · Scientific Reports
Endosomal dysfunction impacts extracellular vesicle release: Central role in Aβ pathology
Bruno Dutra Arbo, Laura Reck Cechinel, Roberta Passos Palazzo, Ionara Rodrigues Siqueira · 2019 · Ageing Research Reviews
How and why to build a mathematical model: A case study using prion aggregation
Mikahl Banwarth-Kuhn, Suzanne Sindi · 2020 · Journal of Biological Chemistry
Implications of mRNA translation dysregulation for neurological disorders
Aya Jishi, Xin Qi, Helen C. Miranda · 2020 · Seminars in Cell and Developmental Biology
Prospective Role of Polyphenolic Compounds in the Treatment of Neurodegenerative Diseases
Rokeya Akter, Habibur Rahman, Tapan Behl, Md. Arifur Rahman Chowdhury, Mohammad Manirujjaman, Israt Jahan Bulbul, Shimaa E. Elshenawy, Delia Mirela Ţiţ, SIMONA GABRIELA BUNGAU · 2021 · CNS & Neurological Disorders - Drug Targets
(Dis‐)Connected Dots in Dementia with Lewy Bodies—A Systematic Review of Connectivity Studies
Annegret Habich, Lars‐Olof Wahlund, Eric Westman, Thomas Dierks, Daniel Ferreira · 2022 · Movement Disorders
Autophagy and Autophagy-Related Proteins in CNS Autoimmunity
Christian W. Keller, Jan D. Lünemann · 2017 · Frontiers in Immunology
Predictive Model of Spread of Progressive Supranuclear Palsy Using Directional Network Diffusion
Sneha Pandya, Christopher Mezias, Ashish Raj · 2017 · Frontiers in Neurology
Evidence of corticofugal tau spreading in patients with frontotemporal dementia
Eun‐Joo Kim, Jihye Hwang, Stephanie E. Gaus, Alissa L. Nana, Jersey Deng, Jesse A. Brown, Salvatore Spina, Myung Jun Lee, Eliana Marisa Ramos, Lea T. Grinberg et al. · 2019 · Acta Neuropathologica
Praja1 RING ‐finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP ‐43 aggregate formation
Kazuhiko Watabe, Yoichiro Kato, Miho Sakuma, Makiko Murata, Motoko Niida‐Kawaguchi, Taro Takemura, Nobutaka Hanagata, Mari Tada, Akiyoshi Kakita, Noriyuki Shibata · 2020 · Neuropathology
Relationship between Neuroprotective Effects and Structure of Procyanidins
Juan Chen, Yixuan Chen, Yangfan Zheng, Jiawen Zhao, Huilin Yu, Jiajin Zhu · 2022 · Molecules
Cellular mechanisms responsible for cell-to-cell spreading of prions
Didier Vilette, Josquin Courte, Jean‐Michel Peyrin, Laurent Coudert, Laurent Schaeffer, Olivier Andréoletti, Pascal Leblanc · 2018 · Cellular and Molecular Life Sciences