A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

Timinszky, Gyula, Till, Susanne, Hassa, Paul O, Hothorn, Michael, Kustatscher, Georg, Nijmeijer, Bianca, Colombelli, Julien, Altmeyer, Matthias, Stelzer, Ernst H K, Scheffzek, Klaus, Hottiger, Michael O, Ladurner, Andreas G·2009·Nature Structural & Molecular Biology
DOI 10.1038/nsmb.1664

Cited by (415)

Items 101–200 of 415

  1. The taming of PARP1 and its impact on NAD+ metabolism
    Sarah Hurtado-Bagès, Gunnar Knobloch, Andreas G. Ladurner, Marcus Buschbeck · 2020 · Molecular Metabolism
  2. The chromatin remodeler ALC1 underlies resistance to PARP inhibitor treatment
    Szilvia Juhász, Rebecca Smith, Tamás Schauer, Dóra Spekhardt, Hasan Mamar, Siham Zentout, Catherine Chapuis, Sébastien Huet, Gyula Timinszky · 2020 · Science Advances
  3. Transcriptional modulator H2A histone family, member Y ( H2AFY ) marks Huntington disease activity in man and mouse
    Yi Hu, Vanita Chopra, Raman Chopra, Joseph J. Locascio, Zhixiang Liao, Hongliu Ding, Bin Zheng, Wayne R. Matson, Robert J. Ferrante, Herminia Diana Rosas et al. · 2011 · Proceedings of the National Academy of Sciences
  4. Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells
    Mahesh Ramamoorthy, Susan Harless Smith · 2015 · Cancer Cell
  5. Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency
    Vincent Pasque, Aliaksandra Radzisheuskaya, Astrid Gillich, Richard P. Halley‐Stott, Maryna Panamarova, Magdalena Zernicka‐Goetz, M. Azim Surani, José Silva · 2012 · Journal of Cell Science
  6. Epigenomic strategies at the interface of genetic and environmental risk factors for autism
    LaSalle, Janine M · 2013 · Journal of Human Genetics
  7. Specificity of reversible ADP-ribosylation and regulation of cellular processes
    Kerryanne Crawford, Juán José Bonfiglio, Andreja Mikoč, Ivan Matić, Ivan Ahel · 2017 · Critical Reviews in Biochemistry and Molecular Biology
  8. Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer
    David Corujo, Marcus Buschbeck · 2018 · Cancers
  9. Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response
    Michael Tallis, Rosa Morra, Eva Barkauskaite, Ivan Ahel · 2013 · Chromosoma
  10. Chromatin enrichment for proteomics
    Georg Kustatscher, Karen L H Wills, Cristina Furlan, Juri Rappsilber · 2014 · Nature Protocols
  11. Structure and mechanism of a canonical poly(ADP-ribose) glycohydrolase
    Mark S. Dunstan, Eva Barkauskaite, Pierre Lafite, Claire E. Knezevic, Amy Brassington, Marijan Ahel, Paul J. Hergenrother, David Leys, Ivan Ahel · 2012 · Nature Communications
  12. Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response
    Guangyao Li, Richard D. McCulloch, Amanda L. Fenton, Melissa Cheung, Li Meng, Mitsuhiko Ikura, Christine Anne Koch · 2010 · Proceedings of the National Academy of Sciences
  13. The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy
    M.M. Javle, Nicola J. Curtin · 2011 · Therapeutic Advances in Medical Oncology
  14. PARP1: Liaison of Chromatin Remodeling and Transcription
    Wen Zong, Yamin Gong, Wenli Sun, Tangliang Li, Zhao‐Qi Wang · 2022 · Cancers
  15. Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy
    Stephen A. Jannetti, Brian M. Zeglis, Michael R. Zalutsky, Thomas Reiner · 2020 · Frontiers in Pharmacology
  16. CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation
    Rebecca Smith, Hafida Sellou, Catherine Chapuis, Sébastien Huet, Gyula Timinszky · 2018 · Nucleic Acids Research
  17. Expanding functions of ADP-ribosylation in the maintenance of genome integrity
    Kathline Martin-Hernandez, José Manuel Rodríguez-Vargas, Valérie Schreiber, Françoise Dantzer · 2016 · Seminars in Cell and Developmental Biology
  18. The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks
    Charlotte Blessing, Imke K. Mandemaker, Claudia Gonzalez-Leal, Julia Preißer, Adrian Schomburg, Andreas G. Ladurner · 2020 · Molecular Cell
  19. How to kill tumor cells with inhibitors of poly(ADP‐ribosyl)ation
    Aswin Mangerich, Alexander Bürkle · 2010 · International Journal of Cancer
  20. A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene
    Hari R. Singh, Aurelio Pio Nardozza, Ingvar R. Möller, Gunnar Knobloch, Hans A. V. Kistemaker, Markus Hassler, Nadine Harrer, Charlotte Blessing, Sebastian Eustermann, Christiane Kotthoff et al. · 2017 · Molecular Cell
  21. New readers and interpretations of poly(ADP-ribosyl)ation
    Thomas Kalisch, Jean‐Christophe Amé, Françoise Dantzer, Valérie Schreiber · 2012 · Trends in Biochemical Sciences
  22. Orphan Macrodomain Protein (Human C6orf130) Is an O-Acyl-ADP-ribose Deacylase
    Francis C. Peterson, Dawei Chen, Betsy L. Lytle, Marianna Nicoletta Rossi, Ivan Ahel, John M. Denu, Brian F. Volkman · 2011 · Journal of Biological Chemistry
  23. CHFR is important for the first wave of ubiquitination at DNA damage sites
    Chao Liu, Jiaxue Wu, Sharad C. Paudyal, Zhongsheng You, Xiaochun Yu · 2012 · Nucleic Acids Research
  24. Poly-ADP ribosylation in DNA damage response and cancer therapy
    Wei‐Hsien Hou, Shih-Hsun Chen, Xiaochun Yu · 2017 · Mutation Research/Reviews in Mutation Research
  25. MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms
    Marek Kozłowski, David Corujo, Michael Hothorn, Iva Guberović, Imke K. Mandemaker, Charlotte Blessing, Judith C. Sporn, José Arturo Gutiérrez Triana, Rebecca Smith, Thomas Portmann et al. · 2018 · EMBO Reports
  26. Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation
    Narasimharao Nalabothula, Taha Al-jumaily, Abdallah M. Eteleeb, Robert M Flight, Xiaorong Shao, Hunter Moseley, Eric Christian Rouchka, Yvonne N. Fondufe‐Mittendorf · 2015 · PLoS ONE
  27. HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage
    Rebecca Smith, Siham Zentout, Magdalena B. Rother, Nicolas Bigot, Catherine Chapuis, Alexandra Mihuț, Florian Zobel, Ivan Ahel, Haico van Attikum, Gyula Timinszky et al. · 2023 · Nature Structural & Molecular Biology
  28. ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells
    Stephen J. Roper, Stephanie Chrysanthou, Claire E. Senner, Arnold R. Sienerth, Stefano Gnan, Alexander Murray, Mitsuko Masutani, Paulina A. Latos, Myriam Hemberger · 2014 · Nucleic Acids Research
  29. Reshaping Chromatin after DNA Damage: The Choreography of Histone Proteins
    Sophie E. Polo · 2014 · Journal of Molecular Biology
  30. Poly(ADP-ribose)-dependent chromatin unfolding facilitates the association of DNA-binding proteins with DNA at sites of damage
    Rebecca Smith, Théo Lebeaupin, Szilvia Juhász, Catherine Chapuis, Ostiane D’Augustin, Stéphanie Dutertre, Peter Burkovics, Christian Biertümpfel, Gyula Timinszky, Sébastien Huet · 2019 · Nucleic Acids Research
  31. Melatonin regulates PARP 1 to control the senescence‐associated secretory phenotype ( SASP ) in human fetal lung fibroblast cells
    Songtao Yu, Xiaojiao Wang, Peiliang Geng, Xu-Dong Tang, Lisha Xiang, Xin Lu, Jianjun Li, Zhihua Ruan, Jianfang Chen, Ganfeng Xie et al. · 2017 · Journal of Pineal Research
  32. Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression
    Magdalena Murawska, Markus Hassler, Renate Renkawitz‐Pohl, Andreas G. Ladurner, Alexander Brehm · 2011 · PLoS Genetics
  33. Mice without MacroH2A Histone Variants
    John R. Pehrson, Lakshmi N. Changolkar, Carl Costanzi, Nicolae Adrian Leu · 2014 · Molecular and Cellular Biology
  34. PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response
    Lisa Aberle, Annika Krüger, Julia M. Reber, Michelle Lippmann, Matthias Hufnagel, Michael F. Schmalz, Irmela R. E. A. Trussina, Sarah Schlesiger, Tabea Zubel, Karina Schütz et al. · 2020 · Nucleic Acids Research
  35. Histone variant macroH2A: from chromatin deposition to molecular function
    Zhen Sun, Emily Bernstein · 2019 · Essays in Biochemistry
  36. PARP, transcription and chromatin modeling
    Melanija Posavec Marjanović, Kerryanne Crawford, Ivan Ahel · 2016 · Seminars in Cell and Developmental Biology
  37. The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1
    Xu, Chang, Xu, Ye, Gursoy-Yuzugullu, Ozge, Price, Brendan D. · 2012 · FEBS Letters
  38. Tripartite Motif-containing 33 (TRIM33) Protein Functions in the Poly(ADP-ribose) Polymerase (PARP)-dependent DNA Damage Response through Interaction with Amplified in Liver Cancer 1 (ALC1) Protein
    Atul Kulkarni, Jay H Oza, Ming Yao, Honeah Sohail, Vasudeva Ginjala, Antonia Tomás‐Loba, Zuzana Hořejšı́, Antoinette R. Tan, Simon J. Boulton, Shridar Ganesan · 2013 · Journal of Biological Chemistry
  39. Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element
    In‐Kwon Kim, James R. Kiefer, Chris M. W. Ho, Roderick A. Stegeman, Scott Classen, John A. Tainer, Tom Ellenberger · 2012 · Nature Structural & Molecular Biology
  40. Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD+/SIRT6 axis
    Christopher A. Koczor, Kate M. Saville, Joel Andrews, Jennifer Clark, Qingming Fang, Jianfeng Li, Rasha Q. Al‐Rahahleh, Md Ibrahim, Steven B McClellan, Mikhail V. Makarov et al. · 2021 · Cell Reports
  41. PARPs and ADP-ribosylation: Deciphering the complexity with molecular tools
    Morgan Dasovich, Anthony K. L. Leung · 2023 · Molecular Cell
  42. Chromatin dynamics in DNA double-strand break repair
    Lei Shi, Philipp Oberdoerffer · 2012 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  43. Do different neurons age differently? Direct genome-wide analysis of aging in single identified cholinergic neurons
    Leonid L. Moroz · 2010 · Frontiers in Aging Neuroscience
  44. Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin
    Lakshmi N. Changolkar, Geetika Singh, Kairong Cui, Joel B. Berletch, Keji Zhao, Christine M. Distèche, John R. Pehrson · 2010 · Molecular and Cellular Biology
  45. Proteomics of a fuzzy organelle: interphase chromatin
    Georg Kustatscher, Nadia Hégarat, Karen L H Wills, Cristina Furlan, Jimi C. Wills, Helfrid Hochegger, Juri Rappsilber · 2014 · The EMBO Journal
  46. PARPs in genome stability and signal transduction: implications for cancer therapy
    Luca Palazzo, Ivan Ahel · 2018 · Biochemical Society Transactions
  47. Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling
    T. Karlberg, Marie-France Langelier, John M. Pascal, Herwig Schuler · 2013 · Molecular Aspects of Medicine
  48. Large-scale preparation and characterization of poly(ADP-ribose) and defined length polymers
    Edwin S. Tan, Kristin A. Krukenberg, Timothy John Mitchison · 2012 · Analytical Biochemistry
  49. Roles of Poly(ADP-Ribose) Glycohydrolase in DNA Damage and Apoptosis
    Xiaoxing Feng, David W. Koh · 2013 · International review of cytology
  50. Solid tumours hijack the histone variant network
    Flávia G. Ghiraldini, Dan Filipescu, Emily Bernstein · 2021 · Nature reviews. Cancer
  51. Single cell resolution in vivo imaging of DNA damage following PARP inhibition
    Katherine S. Yang, Rainer H. Köhler, Matthieu Landon, Randy J. Giedt, Ralph Weissleder · 2015 · Scientific Reports
  52. The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose)
    Ana P. G. Silva, Daniel Ryan, Yaron Galanty, Jason K. K. Low, Marylène S. Vandevenne, Stephen P. Jackson, Joel P. Mackay · 2015 · Journal of Biological Chemistry
  53. PARP Inhibitors in Prostate Cancer
    Praveen Ramakrishnan Geethakumari, Matthew Joseph Schiewer, Karen E. Knudsen, Wm. Kevin Kelly · 2017 · Current Treatment Options in Oncology
  54. MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption
    Melanija Posavec Marjanović, Sarah Hurtado-Bagès, Maximilian Lassi, Vanesa Valero, Roberto Malinverni, Hélène Delage, Miriam Navarro, David Corujo, Iva Guberović, Julien Douet et al. · 2017 · Nature Structural & Molecular Biology
  55. The expanding role of PARP s in the establishment and maintenance of heterochromatin
    Françoise Dantzer, Raffaella Santoro · 2013 · FEBS Journal
  56. Method for the Synthesis of Mono-ADP-ribose Conjugated Peptides
    Peter Michael Moyle, Tom W. Muir · 2010 · Journal of the American Chemical Society
  57. Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease
    Rabindranath De La Fuente, Claudia Baumann, Maria M. Viveiros · 2011 · Reproduction
  58. DNA Damage Triggers a New Phase in Neurodegeneration
    Fabio Pessina, Ubaldo Gioia, Ornella Brandi, Stefania Farina, Marta Ceccon, Sofia Francia, Fabrizio d’Adda di Fagagna · 2020 · Trends in Genetics
  59. Histone H2A variants: Diversifying chromatin to ensure genome integrity
    Philipp Oberdoerffer, Kyle M. Miller · 2022 · Seminars in Cell and Developmental Biology
  60. Activation of the SNF2 Family ATPase ALC1 by Poly(ADP-ribose) in a Stable ALC1·PARP1·Nucleosome Intermediate
    Aaron J. Gottschalk, Rushi D. Trivedi, Joan Weliky Conaway, Ronald C. Conaway · 2012 · Journal of Biological Chemistry
  61. SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation
    Valerio Pazienza, Michela Borghesan, Tommaso Mazza, Fareeba Sheedfar, Concetta Panebianco, Roger L. Williams, Gianluigi Mazzoccoli, Angelo Andriulli, Tomoko Nakanishi, Manlio Vinciguerra · 2014 · Aging
  62. Structural insight into the interaction of ADP‐ribose with the PARP WWE domains
    Fahu He, Kengo Tsuda, Mari Takahashi, Kanako Kuwasako, Takaho Terada, Mikako Shirouzu, Satoru Watanabe, T. Kigawa, Naohiro Kobayashi, Peter Güntert et al. · 2012 · FEBS Letters
  63. BAL1/ARTD9 represses the anti-proliferative and pro-apoptotic IFNγ-STAT1-IRF1-53 axes in diffuse large B-cell lymphoma
    Rosalba Camicia, Samia B. Bachmann, Hans Christian Winkler, Marc Beer, Marianne Tinguely, Eugenia Haralambieva, Paul O. Hassa · 2013 · Journal of Cell Science
  64. Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62
    H. O. Kleine, Andreas Herrmann, Trond Lamark, Alexandra H Forst, Patricia Verheugd, Juliane Lüscher‐Firzlaff, Barbara E. Lippok, Karla L. H. Feijs, Nicolas Herzog, Elisabeth Kremmer et al. · 2012 · Cell Communication and Signaling
  65. In vivo vizualisation of mono-ADP-ribosylation by dPARP16 upon amino-acid starvation
    Angelica Aguilera-Gomez, Marinke M. van Oorschot, Tineke Veenendaal, Cathérine Rabouille · 2016 · eLife
  66. Super-resolution localization microscopy of radiation-induced histone H2AX-phosphorylation in relation to H3K9-trimethylation in HeLa cells
    Michael Hausmann, Emma Wagner, Jin-Ho Lee, Gerrit Schrock, Wladimir Schaufler, Matthias Krufczik, Franziska Papenfuß, Matthias Port, Felix Bestvater, Harry Scherthan · 2018 · Nanoscale
  67. Both ADP-Ribosyl-Binding and Hydrolase Activities of the Alphavirus nsP3 Macrodomain Affect Neurovirulence in Mice
    Rachy Abraham, Robert Lyle McPherson, Morgan Dasovich, Mohsen Badiee, Anthony K. L. Leung, Diane E. Griffin · 2020 · mBio
  68. High-Affinity Interaction of Poly(ADP-ribose) and the Human DEK Oncoprotein Depends upon Chain Length
    Jörg Fahrer, Oliver Popp, Maria Malanga, Sascha Beneke, David M. Markovitz, Elisa Ferrando‐May, Alexander Bürkle, Ferdinand Kappes · 2010 · Biochemistry
  69. ADP-ribosylation: from molecular mechanisms to human disease
    Nícolas C. Hoch, Luis Mariano Polo · 2019 · Genetics and Molecular Biology
  70. Control of the chromatin response to DNA damage: Histone proteins pull the strings
    Juliette Ferrand, Alexandre Plessier, Sophie E. Polo · 2020 · Seminars in Cell and Developmental Biology
  71. Histone Variants: Guardians of Genome Integrity
    Juliette Ferrand, Beatrice Rondinelli, Sophie E. Polo · 2020 · Cells
  72. ADP‐ribosylation of histones by ARTD1: An additional module of the histone code?
    Michael O. Hottiger · 2011 · FEBS Letters
  73. CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
    Magdalena B. Rother, Stefania Pellegrino, Rebecca Smith, Marco Gatti, Cornelia Meisenberg, Wouter W. Wiegant, Martijn S. Luijsterburg, Ralph Imhof, Jessica A. Downs, Alfred C.O. Vertegaal et al. · 2020 · Nature Communications
  74. MacroH2A – An epigenetic regulator of cancer
    Neus Cantariño, Julien Douet, Marcus Buschbeck · 2013 · Cancer Letters
  75. The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer
    Mathieu Dalvai, Kerstin Bystricky · 2010 · Journal of Mammary Gland Biology and Neoplasia
  76. Epigenetic Reprogramming of Mouse Germ Cells toward Totipotency
    M. Azim Surani, Petra Hájková · 2010 · Cold Spring Harbor Symposia on Quantitative Biology
  77. Molecular Insights into Poly(ADP-ribose) Recognition and Processing
    Roko Žaja, Andreja Mikoč, Eva Barkauskaite, Ivan Ahel · 2012 · Biomolecules
  78. Macrodomain ADP-ribosylhydrolase and the pathogenesis of infectious diseases
    Anthony K. L. Leung, Robert Lyle McPherson, Diane E. Griffin · 2018 · PLoS Pathogens
  79. Bioorthogonally Functionalized NAD+ Analogues for In‐Cell Visualization of Poly(ADP‐Ribose) Formation
    Sarah Schlesiger, Annette Buntz, Yan Wang, Andreas Zumbusch, Andreas Marx · 2016 · Angewandte Chemie International Edition
  80. Poly(ADP-ribosyl)ation enhances nucleosome dynamics and organizes DNA damage repair components within biomolecular condensates
    Michael L. Nosella, Tae Hun Kim, Shuya Kate Huang, Robert W. Harkness V, Monica M. Goncalves, Alisia Pan, Maria Tereshchenko, Siavash Vahidi, John L. Rubinstein, Hyun O. Lee et al. · 2024 · Molecular Cell
  81. The basic linker of macroH2A stabilizes DNA at the entry/exit site of the nucleosome
    Srinivas Chakravarthy, Ashok Kumar Patel, Gregory D. Bowman · 2012 · Nucleic Acids Research
  82. MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
    Anuratha Sakthianandeswaren, Marie J. Parsons, Dmitri Mouradov, Ruth N. MacKinnon, Bruno Catimel, Sheng Liu, Michelle Palmieri, Christopher G. Love, Robert N. Jorissen, Shan Li et al. · 2018 · Cancer Discovery
  83. The Multifactorial Role of PARP-1 in Tumor Microenvironment
    Juan Manuel Martí, Mónica Fernández‐Cortés, Santiago Serrano-Sáenz, Esteban Zamudio-Martínez, Daniel Delgado‐Bellido, Ángel García-Díaz, Francisco Javier Oliver · 2020 · Cancers
  84. Pharmacologic Induction of BRCAness in BRCA-Proficient Cancers: Expanding PARP Inhibitor Use
    Rachel Abbotts, Anna J. Dellomo, Feyruz Virgilia Rassool · 2022 · Cancers
  85. Learning How to Read ADP-Ribosylation
    H. O. Kleine, Bernhard Lüscher · 2009 · Cell
  86. Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress
    Stefania Pellegrino, Matthias Altmeyer · 2016 · Frontiers in Genetics
  87. To spread or not to spread—chromatin modifications in response to DNA damage
    Matthias Altmeyer, Jiri Lukas · 2013 · Current Opinion in Genetics & Development
  88. Proteomics approaches to identify mono‐(ADP‐ribosyl)ated and poly(ADP‐ribosyl)ated proteins
    Christina A. Vivelo, Anthony K. L. Leung · 2014 · PROTEOMICS
  89. The Multiple Facets of ATRX Protein
    Martina Valenzuela, Roberta Amato, Antonella Sgura, Antonio Antoccia, Francesco Berardinelli · 2021 · Cancers
  90. DNA repair factor APLF acts as a H2A-H2B histone chaperone through binding its DNA interaction surface
    Ivan Corbeski, Klemen Dolinar, Hans Wienk, Rolf Boelens, Hugo van Ingen · 2018 · Nucleic Acids Research
  91. Chromatin Regulation of DNA Damage Repair and Genome Integrity in the Central Nervous System
    Ling Pan, Jay Penney, Li‐Huei Tsai · 2014 · Journal of Molecular Biology
  92. SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress
    Ingrid Kassner, Anneli Andersson, Monika Fey, Martin Tomas, Elisa Ferrando‐May, Michael O. Hottiger · 2013 · Open Biology
  93. Transcription-associated histone pruning demarcates macroH2A chromatin domains
    Zhen Sun, Dan Filipescu, Joshua Andrade, Alexandre Gaspar‐Maia, Beatrix M. Ueberheide, Emily Bernstein · 2018 · Nature Structural & Molecular Biology
  94. Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability
    Robin Sebastian, Eri K. Hosogane, Eric G. Sun, Andy D. Tran, William C. Reinhold, Sandra Sczerba Burkett, David M. Sturgill, Prabhakar R. Gudla, Yves G. Pommier, Mirit I. Aladjem et al. · 2020 · Molecular Cell
  95. The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
    Xiaoping Xu, Kai Ni, Yafeng He, Jianke Ren, Chongkui Sun, Yie Liu, Mirit I. Aladjem, Sandra Sczerba Burkett, Richard Finney, Xia Ding et al. · 2021 · Nature Communications
  96. The role of ADP-ribosylation in regulating DNA double-strand break repair
    Catherine J. Pears, C. Anne-Marie Couto, Hongyu Wang, Christine Borer, Rhian Kiely, Nick D. Lakin · 2012 · Cell Cycle
  97. The Chromatin Landscape Channels DNA Double-Strand Breaks to Distinct Repair Pathways
    Zulong Chen, Jessica K. Tyler · 2022 · Frontiers in Cell and Developmental Biology
  98. The histone variant MacroH2A regulates Ca2+ influx through TRPC3 and TRPC6 channels
    J-M Kim, Kyu Heo, Jinah Choi, Kyeungpyo Kim, Woojin An · 2013 · Oncogenesis
  99. Macro domains as metabolite sensors on chromatin
    Melanija Posavec Marjanović, Gyula Timinszky, Marcus Buschbeck · 2013 · Cellular and Molecular Life Sciences
  100. Site-Specific Noncovalent Interaction of the Biopolymer Poly(ADP-ribose) with the Werner Syndrome Protein Regulates Protein Functions
    Oliver Popp, Sebastian Veith, Jörg Fahrer, Vilhelm A. Bohr, Alexander Bürkle, Aswin Mangerich · 2012 · ACS Chemical Biology