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Cited by 394

The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.

Saliva: potential diagnostic value and transmission of 2019-nCoV

Open access
Xu, Ruoshi, Cui, Bomiao, Duan, Xiaobo, Zhang, Ping, Zhou, Xuedong, Yuan, Quan·2020·International Journal of Oral Science

Abstract

2019-nCoV epidemic was firstly reported at late December of 2019 and has caused a global outbreak of COVID-19 now. Saliva, a biofluid largely generated from salivary glands in oral cavity, has been reported 2019-nCoV nucleic acid positive. Besides lungs, salivary glands and tongue are possibly another hosts of 2019-nCoV due to expression of ACE2. Close contact or short-range transmission of infectious saliva droplets is a primary mode for 2019-nCoV to disseminate as claimed by WHO, while long-distance saliva aerosol transmission is highly environment dependent within indoor space with aerosol-generating procedures such as dental practice. So far, no direct evidence has been found that 2019-nCoV is vital in air flow for long time. Therefore, to prevent formation of infectious saliva droplets, to thoroughly disinfect indoor air and to block acquisition of saliva droplets could slow down 2019-nCoV dissemination. This review summarizes diagnostic value of saliva for 2019-nCoV, possibly direct invasion into oral tissues, and close contact transmission of 2019-nCoV by saliva droplets, expecting to contribute to 2019-nCoV epidemic control.

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Metadata

Authors
Xu, R., Cui, B., Duan, X., Zhang, P., Zhou, X., & Yuan, Q.
Venue
International Journal of Oral Science
Published
2020-04-17
Volume
12
Issue
1
Pages
11-11
ISSN
  • 1674-2818 (ISSN-L)
  • 2049-3169
OpenAlex
W3016764858
Cited by
394
References
70
FWCI
10.89
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Saliva: potential diagnostic value and transmission of 2019-nCoV. https://app.cochat.ai/papers/10.1038/s41368-020-0080-z
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Xu, R., Cui, B., Duan, X., Zhang, P., Zhou, X., & Yuan, Q. (2020). Saliva: potential diagnostic value and transmission of 2019-nCoV. International Journal of Oral Science. https://doi.org/10.1038/s41368-020-0080-z

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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