History and progress of hypotheses and clinical trials for Alzheimer’s disease

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864

Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Corder, E. H., Saunders, A. M., Strittmatter, W. J., Schmechel, D. E., Gaskell, P. C., Small, G. W., Roses, A. D., Haines, J. L., & Pericak-Vance, M. A. (1993) · Science · doi:10.1126/science.8346443 · Cited by 9,429

Autophagy: Renovation of Cells and Tissues

Mizushima, N., & Komatsu, M. (2011) · Cell · doi:10.1016/j.cell.2011.10.026 · Cited by 6,615

Autophagy fights disease through cellular self-digestion

Mizushima, N., Levine, B., Cuervo, A. M., & Klionsky, D. J. (2008) · Nature · doi:10.1038/nature06639 · Cited by 6,452

Neuroinflammation in Alzheimer's disease

Heneka, M. T., Carson, M. J., Khoury, J. E., Landreth, G. E., Brosseron, F., Feinstein, D. L., Jacobs, A. H., Wyss-Coray, T., Vitorica, J., Ransohoff, R. M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)70016-5 · Cited by 6,226

IDH1 and IDH2 Mutations in Gliomas

Yan, H., Parsons, D. W., Jin, G., McLendon, R., Rasheed, B. A., Yuan, W., Kos, I., Batinic-Haberle, I., Jones, S., Riggins, G. J., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0808710 · Cited by 5,847

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003748 · Cited by 5,824

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

Glenner, G. G., & Wong, C. W. (1984) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(84)80190-4 · Cited by 5,404

Design, synthesis and in vitro biological activities of coumarin linked 1,3,4-oxadiazole hybrids as potential multi-target directed anti-Alzheimer agents

George, N., Sabahi, B. A., AbuKhader, M., Balushi, K. A. A., Akhtar, M. J., & Khan, S. A. (2022) · Journal of King Saud University - Science · doi:10.1016/j.jksus.2022.101977 · Cited by 50

Neuroinflammation as a mechanism linking hypertension with the increased risk of Alzheimer’s disease

Klegeris, A., & Bajwa, E. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.336869 · Cited by 49

Molecular mechanisms and therapeutic potential of icariin in the treatment of Alzheimer's disease

Zheng, L., Wu, S., Jin, H., Wu, J., Wang, X., Cao, Y., Zhou, Z., Jiang, Y., Li, L., Yang, X., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154890 · Cited by 48

“Drug‐Carrier” Synergy Therapy for Amyloid‐β Clearance and Inhibition of Tau Phosphorylation via Biomimetic Lipid Nanocomposite Assembly

Han, G., Bai, K., Yang, X., Sun, C., Ji, Y., Zhou, J., Zhang, H., & Ding, Y. (2022) · Advanced Science · doi:10.1002/advs.202106072 · Cited by 46

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis

Sampietro, A., Pérez-Areales, F. J., Martínez, P., Arce, E. M., Galdeano, C., & Muñoz‐Torrero, D. (2022) · Pharmaceuticals · doi:10.3390/ph15050545 · Cited by 46

c-Jun N-Terminal Kinase Inhibitors as Potential Leads for New Therapeutics for Alzheimer’s Diseases

Rehfeldt, S. C. H., Majolo, F., Goettert, M. I., & Laufer, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249677 · Cited by 47

Flavonoid-Based Nanomedicines in Alzheimer’s Disease Therapeutics: Promises Made, a Long Way To Go

Prasanna, P., & Upadhyay, A. (2021) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.0c00224 · Cited by 48

Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer’s Disease Symptoms

Hosseini, S., Michaelsen‐Preusse, K., Schughart, K., & Körte, M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.643650 · Cited by 46

Advanced theragnostics for the central nervous system (CNS) and neurological disorders using functional inorganic nanomaterials

Conklin, B., Conley, B. M., Hou, Y., Chen, M., & Lee, K.-B. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114636 · Cited by 45

Enhancing the Therapeutic Effect in Alzheimer's Disease Drugs: The role of Polypharmacology and Cholinesterase inhibitors

Martins, M. M., Branco, P. S., & Ferreira, L. M. (2023) · ChemistrySelect · doi:10.1002/slct.202300461 · Cited by 50

Therapeutic potential of the medicinal mushroom Ganoderma lucidum against Alzheimer's disease

Chen, X.-J., Deng, Z., Zhang, L., Pan, Y., Fu, J., Zou, L., Bai, Z., Xiao, X., & Sheng, F. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116222 · Cited by 47

Newer Therapeutic Approaches in Treating Alzheimer’s Disease: A Comprehensive Review

Sree, R. R., Kalyan, M., Anand, N., Mani, S., Gorantla, V. R., Sakharkar, M. K., Song, B., & Chidambaram, S. B. (2025) · ACS Omega · doi:10.1021/acsomega.4c05527 · Cited by 45

Alzheimer’s Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α

Sáez-Orellana, F., Octave, J., & Pierrot, N. (2020) · Cells · doi:10.3390/cells9051215 · Cited by 47

Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1–42 infused rat model

Elibol, B., Beker, M., Uşak, Ş. T., Dallı, T., & Kılıç, Ü. (2020) · Phytomedicine · doi:10.1016/j.phymed.2020.153324 · Cited by 46

Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Martinez, J. L., Zammit, M. D., West, N. R., Christian, B. T., & Bhattacharyya, A. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.703876 · Cited by 47

Brain-on-a-chip: An emerging platform for studying the nanotechnology-biology interface for neurodegenerative disorders

Rodrigues, R. O., Shin, S.-R., & Bañobre-López, M. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02720-0 · Cited by 44

Neuroprotection for Age-Related Macular Degeneration

Lin, J. B., Murakami, Y., Miller, J. W., & Vavvas, D. G. (2022) · Ophthalmology Science · doi:10.1016/j.xops.2022.100192 · Cited by 44

Restoring the epigenome in Alzheimer's disease: advancing HDAC inhibitors as therapeutic agents

Pereira, M. S., Cruz, M. T., Fortuna, A. C., & Bicker, J. (2024) · Drug Discovery Today · doi:10.1016/j.drudis.2024.104052 · Cited by 47

Potential role and therapeutic implications of glutathione peroxidase 4 in the treatment of Alzheimer’s disease

Shen, Y., Zhang, G., Wei, C., Zhao, P., Wang, Y., Li, M., & Sun, L. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01343 · Cited by 44

Recent advancement in understanding of Alzheimer's disease: Risk factors, subtypes, and drug targets and potential therapeutics

Prabha, S., Sajad, M., Hasan, G. M., Islam, A., Hassan, M. I., & Thakur, S. C. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102476 · Cited by 44

Gut-brain axis: gut dysbiosis and psychiatric disorders in Alzheimer’s and Parkinson’s disease

Denman, C. R., Park, S. M., & Jo, J. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1268419 · Cited by 45

Alterations in resting-state network dynamics along the Alzheimer’s disease continuum

Puttaert, D., Coquelet, N., Wens, V., Peigneux, P., Fery, P., Rovaï, A., Trotta, N., Sadeghi, N., Coolen, T., Bier, J. C., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-76201-3 · Cited by 44

Rational drug design strategies for the development of promising multi-target directed indole hybrids as Anti-Alzheimer agents

George, N., Akhtar, M. J., Balushi, K. A. A., & Khan, S. A. (2022) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2022.105941 · Cited by 44

K284-6111 alleviates memory impairment and neuroinflammation in Tg2576 mice by inhibition of Chitinase-3-like 1 regulating ERK-dependent PTX3 pathway

Ham, H. J., Lee, Y. S., Yun, J., Son, D. J., Lee, H. P., Han, S., & Hong, J. T. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-02022-w · Cited by 42

Molecular mechanisms and therapeutic potential of lithium in Alzheimer’s disease: repurposing an old class of drugs

Shen, Y., Zhao, M., Zhao, P., Meng, L., Zhang, Y., Zhang, G., Taishi, Y., & Sun, L. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1408462 · Cited by 45

Neurotechnological Approaches to the Diagnosis and Treatment of Alzheimer’s Disease

Ning, S., Jorfi, M., Patel, S. R., Kim, D. Y., & Tanzi, R. E. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.854992 · Cited by 43

Mitochondria as a promising target for developing novel agents for treating Alzheimer's disease

Shevtsova, E. F., Maltsev, A. V., Vinogradova, D. V., Shevtsov, P. N., & Бачурин, С. О. (2020) · Medicinal Research Reviews · doi:10.1002/med.21715 · Cited by 42

A closer look at the mycobiome in Alzheimer’s disease: Fungal species, pathogenesis and transmission

Phuna, Z. X., & Madhavan, P. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15599 · Cited by 41

Brain Targeting of Citicoline Sodium via Hyaluronic Acid-Decorated Novel Nano-Transbilosomes for Mitigation of Alzheimer’s Disease in a Rat Model: Formulation, Optimization, in vitro and in vivo Assessment

AbouElhassan, K. M., Sarhan, H. A., Hussein, A. K., Taye, A., Ahmed, Y. M., & Safwat, M. A. (2022) · International Journal of Nanomedicine · doi:10.2147/ijn.s381353 · Cited by 40

Tau- and α-synuclein-targeted gold nanoparticles: applications, opportunities, and future outlooks in the diagnosis and therapy of neurodegenerative diseases

Tapia-Arellano, A., Cabrera, P., Cortés-Adasme, E., Riveros, A. L., Hassan, N., & Kogan, M. J. (2024) · Journal of Nanobiotechnology · doi:10.1186/s12951-024-02526-0 · Cited by 40

High-density lipoprotein in Alzheimer's disease: From potential biomarkers to therapeutics

Jin, Y., Chifodya, K., Han, G., Jiang, W., Chen, Y., Shi, Y., Xu, Q., Xi, Y., Wang, J., Zhou, J., et al. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.08.018 · Cited by 41

New Pathways Identify Novel Drug Targets for the Prevention and Treatment of Alzheimer’s Disease

Penke, B., Szűcs, M., & Bogár, F. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065383 · Cited by 39

Targeting Systemic Innate Immune Cells as a Therapeutic Avenue for Alzheimer Disease

Pons, V., & Rivest, S. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000400 · Cited by 41

Neuropharmacology of Organoselenium Compounds in Mental Disorders and Degenerative Diseases

Birmann, P. T., Casaril, A. M., Abenante, L., Penteado, F., Brüning, C. A., Savegnago, L., & Lenardao, E. J. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666220615124412 · Cited by 40

Arc Regulates Transcription of Genes for Plasticity, Excitability and Alzheimer’s Disease

Leung, H.-W., Foo, G., & VanDongen, A. M. J. (2022) · Biomedicines · doi:10.3390/biomedicines10081946 · Cited by 41

The Vascular-Immune Hypothesis of Alzheimer’s Disease

Mehta, R. I., & Mehta, R. I. (2023) · Biomedicines · doi:10.3390/biomedicines11020408 · Cited by 39

Plasma GFAP, NfL and pTau 181 detect preclinical stages of dementia

Ingannato, A., Bagnoli, S., Mazzeo, S., Giacomucci, G., Bessi, V., Ferrari, C., Sorbi, S., & Nacmias, B. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1375302 · Cited by 41

Insulin Resistance as a Common Link Between Current Alzheimer’s Disease Hypotheses

Alves, S. S., da Silva-Júnior, R. M. P., Servilha‐Menezes, G., Homolak, J., Šalković‐Petrišić, M., & Garcia‐Cairasco, N. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210234 · Cited by 39

Phytocannabinoids and Cannabis-Based Products as Alternative Pharmacotherapy in Neurodegenerative Diseases: From Hypothesis to Clinical Practice

Paes-Colli, Y., Aguiar, A. F. L., Isaac, A. R., Ferreira, B. K., Campos, R. M. P., Trindade, P. M. P., Reis, R. A. D. M., & Sampaio, L. D. S. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.917164 · Cited by 39

Golgi fragmentation – One of the earliest organelle phenotypes in Alzheimer’s disease neurons

Haukedal, H., Corsi, G. I., Gadekar, V. P., Doncheva, N. T., Kedia, S., de Haan, N., Chandrasekaran, A., Jensen, P., Schiønning, P., Vallin, S., et al. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2023.1120086 · Cited by 37

Quercetin-Loaded Nanostructured Lipid Carrier In Situ Gel for Brain Targeting Through Intranasal Route: Formulation, In Vivo Pharmacokinetic and Pharmacodynamic Studies

Sonawane, D., & Pokharkar, V. (2024) · AAPS PharmSciTech · doi:10.1208/s12249-024-02736-7 · Cited by 41

Eriodictyol and Homoeriodictyol Improve Memory Impairment in Aβ25–35-Induced Mice by Inhibiting the NLRP3 Inflammasome

Guo, P., Zeng, M., Wang, S., Cao, B., Liu, M., Zhang, Y., Jia, J., Zhang, Q., Zhang, B., Wang, R., et al. (2022) · Molecules · doi:10.3390/molecules27082488 · Cited by 37

Vitamin B12 as a cholinergic system modulator and blood brain barrier integrity restorer in Alzheimer's disease

El-Mezayen, N. S., el Moneim, R. A. A., & El‐Rewini, S. H. (2022) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2022.106201 · Cited by 37

Photobiomodulation in Alzheimer’s Disease—A Complementary Method to State-of-the-Art Pharmaceutical Formulations and Nanomedicine?

Ailioaie, L. M., Ailioaie, C., & Litscher, G. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15030916 · Cited by 40

Carbamate as a potential anti‐Alzheimer's pharmacophore: A review

Singh, Y. P., Kumar, N., Chauhan, B. S., & Garg, P. (2023) · Drug Development Research · doi:10.1002/ddr.22113 · Cited by 36

The relationship between hypoxia and Alzheimer’s disease: an updated review

Tao, B., Gong, W., Xu, C., Ma, Z., Mei, J., & Chen, M. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1402774 · Cited by 36

Evidence for aggregation-independent, PrP C -mediated Aβ cellular internalization

Foley, A. R., Roseman, G. P., Chan, K., Smart, A., Finn, T. S., Yang, K., Lokey, R. S., Millhauser, G. L., & Raskatov, J. A. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2009238117 · Cited by 38

Liver Bile Acid Changes in Mouse Models of Alzheimer’s Disease

Kaur, H., Seeger, D. R., Golovko, S. A., Golovko, M. Y., & Combs, C. K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22147451 · Cited by 36

Stepwise Coordination-Driven Metal–Phenolic Nanoparticle as a Neuroprotection Enhancer for Alzheimer’s Disease Therapy

Yin, Z., Zhang, Z., Gao, D., Luo, G., Ma, T., Wang, Y., Lu, L., & Gao, X. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c18060 · Cited by 38

Secondary Metabolites from Plants Possessing Inhibitory Properties against Beta-Amyloid Aggregation as Revealed by Thioflavin-T Assay and Correlations with Investigations on Transgenic Mouse Models of Alzheimer's Disease

Stefanescu, R., Stanciu, G. D., Luca, A., Paduraru, L., & Tamba, B.-I. (2020) · Biomolecules · doi:10.3390/biom10060870 · Cited by 35

Unravelling the in vitro and in vivo potential of selenium nanoparticles in Alzheimer's disease: A bioanalytical review

Vicente-Zurdo, D., Rosales‐Conrado, N., & León‐González, M. E. (2023) · Talanta · doi:10.1016/j.talanta.2023.125519 · Cited by 36

Controversial Past, Splendid Present, Unpredictable Future: A Brief Review of Alzheimer Disease History

Bermejo‐Pareja, F., & del Ser, T. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020536 · Cited by 39

Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation

Šneiderienė, G., Díaz, A. G., Dasadhikari, S., Wei, J., Michaels, T. C. T., Šneideris, T., Linse, S. S., Vendruscolo, M., Garai, K., & Knowles, T. P. J. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2401307122 · Cited by 36

Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer’s disease rats

Song, L., Piao, Z.-Y., Yao, L.-F., Zhang, L.-M., & Lu, Y.-C. (2020) · Experimental animals · doi:10.1538/expanim.19-0146 · Cited by 30

Phytochemical Studies, Antioxidant Potential, and Identification of Bioactive Compounds Using GC–MS of the Ethanolic Extract of Luffa cylindrica (L.) Fruit

Ankul Singh, S., & Vellapandian, C. (2022) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-022-03961-1 · Cited by 36

Butyrylcholinesterase inhibitors as potential anti-Alzheimer’s agents: an updated patent review (2018-present)

Fernández‐Bolaños, J. G., & López, Ó. (2022) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2022.2083956 · Cited by 35

Neurodegeneration: Microglia: Nf-Kappab Signaling Pathways

Singh, A., Ansari, V. A., Mahmood, T., Ahsan, F., & Wasim, R. (2022) · Drug Research · doi:10.1055/a-1915-4861 · Cited by 36

Lessons from antiamyloid-β immunotherapies in Alzheimer's disease

Plascencia‐Villa, G., & Perry, G. L. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-323-85555-6.00019-9 · Cited by 35

Astrocytes as Neuroimmunocytes in Alzheimer’s Disease: A Biochemical Tool in the Neuron–Glia Crosstalk along the Pathogenetic Pathways

Stanca, S., Rossetti, M., & Bongioanni, P. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813880 · Cited by 35

Potential Alzheimer's disease therapeutic nano-platform: Discovery of amyloid-beta plaque disaggregating agent and brain-targeted delivery system using porous silicon nanoparticles

Kim, J., Um, H., Kim, N. H., & Kim, D. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.01.006 · Cited by 33

Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression

Fernández‐Mendívil, C., Arreola, M. A., Hohsfield, L. A., Green, K. N., & López, M. G. (2020) · Antioxidants · doi:10.3390/antiox9070644 · Cited by 33

NIPSNAP protein family emerges as a sensor of mitochondrial health

Fathi, E., Yarbro, J. M., & Homayouni, R. (2021) · BioEssays · doi:10.1002/bies.202100014 · Cited by 35

From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series

Meden, A., Knez, D., Brazzolotto, X., Nachon, F., Dias, J., Svete, J., Stojan, J., Grošelj, U., & Gobec, S. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114248 · Cited by 33

Three‐dimensional bioprinting of stem cell‐derived central nervous system cells enables astrocyte growth, vasculogenesis, and enhances neural differentiation/function

Sullivan, M. A., Lane, S., Volkerling, A. M., Engel, M., Werry, E. L., & Kassiou, M. (2023) · Biotechnology and Bioengineering · doi:10.1002/bit.28470 · Cited by 32

Curcuma wenyujin extract alleviates cognitive deficits and restrains pyroptosis through PINK1/Parkin mediated autophagy in Alzheimer's disease

Qi, Y., Zhang, J., Zhang, Y., Zhu, H., Wang, J., Xu, X., Jin, S., Wang, C., Zhang, F., Zhao, M., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156482 · Cited by 32

New Prospects in the Inhibition of Monoamine Oxidase‑B (MAO-B) Utilizing Propargylamine Derivatives for the Treatment of Alzheimer’s Disease: A Review

Chatzipieris, F. P., Kokkalis, A., Georgiou, N., Petsas, E., Apostolou, E. V., Vougioukalakis, G. C., & Mavromoustakos, T. (2025) · ACS Omega · doi:10.1021/acsomega.5c00134 · Cited by 32

Alzheimer’s Disease: From Molecular Mechanisms to Promising Therapeutic Strategies

Ivanova, A. V., Kutuzova, A. D., Kuzmichev, I., & Abakumov, M. A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199444 · Cited by 33

Phytohormone Abscisic Acid Improves Memory Impairment and Reduces Neuroinflammation in 5xFAD Mice by Upregulation of LanC-Like Protein 2

Jeon, S. H., Kim, N., Ju, Y., Gee, M. S., Lee, D., & Lee, J. K. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21228425 · Cited by 32

The significance of sialylation on the pathogenesis of Alzheimer’s disease

Yang, K., Yang, Z., Chen, X., & Li, W. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.05.009 · Cited by 32

Exploiting mesoporous silica, silver and gold nanoparticles for neurodegenerative diseases treatment

Ribeiro, T. D. C., Sábio, R. M., Carvalho, G. C., Fonseca‐Santos, B., & Chorilli, M. (2022) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2022.121978 · Cited by 33

Review of Advanced Drug Trials Focusing on the Reduction of Brain Beta-Amyloid to Prevent and Treat Dementia

Decourt, B., Noorda, K., Noorda, K. J., Shi, J., & Sabbagh, M. N. (2022) · Journal of Experimental Pharmacology · doi:10.2147/jep.s265626 · Cited by 33

The Role of Heme and Copper in Alzheimer’s Disease and Type 2 Diabetes Mellitus

Pal, I., & Dey, S. G. (2023) · JACS Au · doi:10.1021/jacsau.2c00572 · Cited by 32

An eXplainability Artificial Intelligence approach to brain connectivity in Alzheimer's disease

Amoroso, N., Quarto, S., Rocca, M. L., Tangaro, S., Monaco, A., & Bellotti, R. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1238065 · Cited by 33

Animal models in biomedical research: Relevance of Drosophila melanogaster

Obafemi, T. O., Ayeleso, A. O., Adewale, O. B., Unuofin, J. O., Ekundayo, B. E., Ntwasa, M. M., & Lebelo, S. L. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e41605 · Cited by 33

Dendrimer–tesaglitazar conjugate induces a phenotype shift of microglia and enhances β-amyloid phagocytosis

DeRidder, L. B., Sharma, A., Liaw, K., Sharma, R. B., John, J., Kannan, S., & Kannan, R. M. (2020) · Nanoscale · doi:10.1039/d0nr05958g · Cited by 31

Oral Pathogenic Bacteria-Inducing Neurodegenerative Microgliosis in Human Neural Cell Platform

Tran, V. T. A., Kang, Y. J., Kim, H., Cho, H., & Cho, H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136925 · Cited by 35

Development of iPSC-based clinical trial selection platform for patients with ultrarare diseases

Sequiera, G. L., Srivastava, A., Sareen, N., Yan, W., Alagarsamy, K. N., Verma, E., Aghanoori, M., Aliani, M., Kumar, A., Fernyhough, P., et al. (2022) · Science Advances · doi:10.1126/sciadv.abl4370 · Cited by 31

Peripheral Mitochondrial Dysfunction: A Potential Contributor to the Development of Metabolic Disorders and Alzheimer’s Disease

Sultana, M. A., Hia, R. A., Akinsiku, O., & Hegde, V. K. (2023) · Biology · doi:10.3390/biology12071019 · Cited by 31

Somatostatin and the pathophysiology of Alzheimer’s disease

Almeida, V. N. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102270 · Cited by 31

Alzheimer’s Disease Etiology Hypotheses and Therapeutic Strategies: A Perspective

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