The DOI matches its Crossref record; 554 of the 554 references it cites were found in a registry or an index.
Roles and mechanisms of exosomal non-coding RNAs in human health and diseases
Open accessAbstract
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), are closely related to a variety of biological and functional aspects of human health. When the exosomal ncRNAs undergo tissue-specific changes due to diverse internal or external disorders, they can cause tissue dysfunction, aging, and diseases. In this review, we comprehensively discuss the underlying regulatory mechanisms of exosomes in human diseases. In addition, we explore the current knowledge on the roles of exosomal miRNAs, lncRNAs, and circRNAs in human health and diseases, including cancers, metabolic diseases, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, and infectious diseases, to determine their potential implication in biomarker identification and therapeutic exploration.
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11 retracted
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RetractedRETRACTED: circIFT80 Functions as a ceRNA of miR-1236-3p to Promote Colorectal Cancer Progression
Feng, W., Gong, H., Wang, Y., Zhu, G., Xue, T., Wang, Y., & Cui, G. (2019) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2019.08.024 · Cited by 81
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Retracted
Cited by
Chronic inflammation and the hallmarks of aging
Baechle, J. J., Chen, N., Makhijani, P., Winer, S., Furman, D., & Winer, D. A. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101755 · Cited by 471
Salemi, M., Mogavero, M. P., Lanza, G., Mongioì, L. M., Calogero, A. E., & Ferri, R. (2022) · Cells · doi:10.3390/cells11121930 · Cited by 39
Metadata
- Authors
- Li, C., Ni, Y.-Q., Xu, H., Xiang, Q.-Y., Zhao, Y., Zhan, J.-K., He, J.-Y., Li, S., & Liu, Y.-S.
- Venue
- Signal Transduction and Targeted Therapy
- Published
- 2021-11-10
- Volume
- 6
- Issue
- 1
- Pages
- 383-383
- ISSN
- 2059-3635 (ISSN-L)
- OpenAlex
- W3213709497
- Cited by
- 406
- References
- 554
- FWCI
- 16.30
- Type
- journal article
- Language
- en
- Open access
- gold
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- Li, C., Ni, Y.-Q., Xu, H., Xiang, Q.-Y., Zhao, Y., Zhan, J.-K., He, J.-Y., Li, S., & Liu, Y.-S. (2021). Roles and mechanisms of exosomal non-coding RNAs in human health and diseases. Signal Transduction and Targeted Therapy. https://doi.org/10.1038/s41392-021-00779-x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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