The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Lysosome biology in autophagy
Open accessAbstract
Autophagy is a major intracellular degradation system that derives its degradative abilities from the lysosome. The most well-studied form of autophagy is macroautophagy, which delivers cytoplasmic material to lysosomes via the double-membraned autophagosome. Other forms of autophagy, namely chaperone-mediated autophagy and microautophagy, occur directly on the lysosome. Besides providing the means for degradation, lysosomes are also involved in autophagy regulation and can become substrates of autophagy when damaged. During autophagy, they exhibit notable changes, including increased acidification, enhanced enzymatic activity, and perinuclear localization. Despite their importance to autophagy, details on autophagy-specific regulation of lysosomes remain relatively scarce. This review aims to provide a summary of current understanding on the behaviour of lysosomes during autophagy and outline unexplored areas of autophagy-specific lysosome research.
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Cites
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Cellular senescence in brain aging
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“According to Yim and Mizushima, there are four kinds of autophagy: macroautophagy, chaperon-mediated autophagy (CMA), RN/DNatophagy, and microautophagy (Yim and Mizushima, 2020).”
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The rapidly evolving view of lysosomal storage diseases
Parenti, G., Medina, D. L., & Ballabio, A. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202012836 · Cited by 230
Mishra, S. R., Mahapatra, K. K., Behera, B. P., Patra, S., Bhol, C. S., Panigrahi, D. P., Praharaj, P. P., Singh, A., Patil, S., Dhiman, R., et al. (2021) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2021.106013 · Cited by 195
Metadata
- Authors
- Yim, W. W.-Y., & Mizushima, N.
- Venue
- Cell Discovery
- Published
- 2020-02-11
- Volume
- 6
- Issue
- 1
- Pages
- 6-6
- ISSN
- 2056-5968 (ISSN-L)
- OpenAlex
- W3004905553
- Cited by
- 803
- References
- 18
- FWCI
- 63.89
- Type
- journal article
- Language
- en
- Open access
- gold
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