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A human monoclonal antibody blocking SARS-CoV-2 infection
Open accessPublished version of a preprint
Abstract
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This cross-neutralizing antibody targets a communal epitope on these viruses and may offer potential for prevention and treatment of COVID-19.
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Metadata
- Authors
- Wang, C., Li, W., Drabek, D., Okba, N. M. A., van Haperen, R., Osterhaus, A. D. M. E., van Kuppeveld, F. J. M., Haagmans, B. L., Grosveld, F., & Bosch, B.-J.
- Venue
- Nature Communications
- Published
- 2020-05-04
- Volume
- 11
- Issue
- 1
- Pages
- 2251-2251
- ISSN
- 2041-1723 (ISSN-L)
- OpenAlex
- W3023698680
- Cited by
- 1,132
- References
- 7
- FWCI
- 31.96
- Type
- journal article
- Language
- en
- Update notices
- correction (2020-05-14)
- Open access
- gold
- Licence
- creativecommons.org/licenses/by/4.0 (tdm)
- creativecommons.org/licenses/by/4.0 (vor)
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- The paper
- Wang, C., Li, W., Drabek, D., Okba, N. M. A., van Haperen, R., Osterhaus, A. D. M. E., van Kuppeveld, F. J. M., Haagmans, B. L., Grosveld, F., & Bosch, B.-J. (2020). A human monoclonal antibody blocking SARS-CoV-2 infection. Nature Communications. https://doi.org/10.1038/s41467-020-16256-y
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