The DOI matches its Crossref record; 45 of the 46 references it cites were found in a registry or an index.
A hybrid erbium(III)–bacteriochlorin near-infrared probe for multiplexed biomedical imaging
Open accessAbstract
Spectrally distinct fluorophores are desired for multiplexed bioimaging. In particular, monitoring biological processes in living mammals needs fluorophores that operate in the 'tissue-transparent' near-infrared (NIR) window, that is, between 700 and 1,700 nm. Here we report a fluorophore system based on molecular erbium(III)-bacteriochlorin complexes with large Stokes shift (>750 nm) and narrowband NIR-to-NIR downconversion spectra (full-width at half-maximum ≤ 32 nm). We have found that the fast (2 × 10 9 s-¹) and near-unity energy transfer from bacteriochlorin triplets to the erbium(III) 4 I 13/2 level overcomes the notorious vibrational overtones quenching, resulting in bright and long-lived (1.73 μs) 1,530 nm luminescence in water. We demonstrate the excitation/emission-multiplexed capability of the complexes in the visualization of dynamic circulatory and metabolic processes in living mice, and through skull tracking of cancer cell metastases in mouse brain. This hybrid probe system facilitates robust multiplexed NIR imaging with high contrast and spatial resolution for applications ranging from fluorescence-guided surgery, diagnostics and intravital microscopy.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Citations
Cites
Lanthanide luminescence for functional materials and bio-sciences
Eliseeva, S. V., & Bünzli, J. G. (2009) · Chemical Society Reviews · doi:10.1039/b905604c · Cited by 3,542
Self-citationNear-infrared fluorophores for biomedical imaging
Hong, G., Antaris, A. L., & Dai, H. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0010 · Cited by 3,048
The Fluorescent Toolbox for Assessing Protein Location and Function
Giepmans, B. N. G., Adams, S., Ellisman, M. H., & Tsien, R. Y. (2006) · Science · doi:10.1126/science.1124618 · Cited by 2,782
Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules
Han, M., Gao, X., Su, J. Z., & Nie, S. (2001) · Nature Biotechnology · doi:10.1038/90228 · Cited by 2,632
A small-molecule dye for NIR-II imaging
Antaris, A. L., Chen, H., Cheng, K., Sun, Y., Hong, G., Qu, C., Diao, S., Deng, Z., Hu, X., Zhang, B., et al. (2016) · Nature Materials · doi:10.1038/nmat4476 · Cited by 1,778
Controlling upconversion nanocrystals for emerging applications
Zhou, B., Shi, B., Jin, D., & Liu, X. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.251 · Cited by 1,507
Hu, Z., Fang, C., Li, B., Zhang, Z., Cao, C., Cai, M., Su, S., Sun, X., Shi, X., Li, C., et al. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-019-0494-0 · Cited by 1,126
Lifetime-engineered NIR-II nanoparticles unlock multiplexed in vivo imaging
Fan, Y., Wang, P., Lu, Y., Wang, R., Zhou, L., Zheng, X., Li, X., Piper, J. A., & Zhang, F. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0221-0 · Cited by 802
Self-citationStack, E. C., Wang, C., Roman, K., & Hoyt, C. C. (2014) · Methods · doi:10.1016/j.ymeth.2014.08.016 · Cited by 779
Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury
Huang, J., Li, J., Lyu, Y., Miao, Q., & Pu, K. (2019) · Nature Materials · doi:10.1038/s41563-019-0378-4 · Cited by 729
Research works printed but not linked: 1
- Yerushalmi, R., Ashur, I. & Scherz, A. in Chlorophylls and Bacteriochlorophylls: Biochemistry, Biophysics, Functions and Applications (eds Grimm, B. et al.) 495–506 (Springer Netherlands, 2006).
Cited by
Sorted by citations
Items 101–200 of 308
Recent progress of second near-infrared (NIR-II) fluorescence microscopy in bioimaging
Wang, T., Chen, Y., Wang, B., & Wu, M. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1126805 · Cited by 25
“(Liu et al., 2018; Wang et al., 2021) developed erbiumdoped (Er3+) rare earth near-infrared probes for diagnosis, navigation surgery, and lifetime imaging applications using NIRII with high SBR.”
MethodSelf-citationFu-jia, S., Su, P., Li, X., Yan, C., Zhang, J., & Tang, Y. F. (2026) · Chemical Society Reviews · doi:10.1039/d5cs00384a · Cited by 29
Main Group Elements Activated Near‐Infrared Photonic Materials
Dong, Q., Xu, F. H., Qiu, J., & Zhou, S. (2024) · Laser & Photonics Review · doi:10.1002/lpor.202301053 · Cited by 24
Xia, X., Wang, R., Hu, Y., Long, S., Sun, W. C., Fan, J., & Peng, X. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202507157 · Cited by 23
A high‐performance cell‐labeling NIR‐II dye for in vivo cell tracking
Sun, B., Ma, R., Wang, X., Ma, S., Li, W., Liu, T., Zhu, W., Ji, Z., Hettie, K. S., Liu, C., et al. (2024) · Open Research (University of Surrey) · doi:10.1002/viw.20230097 · Cited by 22
Shi, B., Zhang, L., Yan, K., Ming, J., Chen, Z., Chen, Y., He, H., Zhang, H., Wang, L., Wang, S., et al. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202410118 · Cited by 21
Self-citationAdvanced optical imaging technology in the near infrared window for cell tracking in vivo
Zhao, X., Ma, Y., & Lei, Z. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216178 · Cited by 22
Zheng, J., Wu, B., Xu, F., Shan, T., Li, X., Tian, J. L., & Zhang, W. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123107 · Cited by 22
Self-citationSite-Specific Transformable Nanostructures for Cancer Therapy and Diagnosis
Kim, J., Lee, Y., Kim, Y., Rha, H., Kim, D., Debnath, S., Pu, K., Kang, H., & Kim, J. S. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.5c00297 · Cited by 22
Zhang, J., Zhang, B., Zheng, Z., Cai, Q., Wang, J., Shu, Q., & Wang, L. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202109882 · Cited by 21
Metal‐Based Aggregation‐Induced Emission Theranostic Systems
Shen, H., Xu, C., Sun, F., Zhao, M., Wu, Q., Zhang, J., Li, S., Zhang, J., Lam, J. W. Y., & Tang, B. Z. (2021) · ChemMedChem · doi:10.1002/cmdc.202100578 · Cited by 20
Self-citationWang, K., Fu, J., Zhan, S., Dong, H., Lou, C., Sun, T., Liu, J., Huang, B., Tian, L., Jiang, L., et al. (2024) · Chem · doi:10.1016/j.chempr.2024.09.024 · Cited by 20
Self-citationAn AIE-active near-infrared molecular probe for migrasome labeling
Cui, J. W., Zhang, F., Jiang, D., Liu, B., Zhang, H., Niu, N., Yan, D., Song, G., Li, X., Yu, L., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123213 · Cited by 20
Self-citationWu, K., Chao, Z., Aji, S., Zhu, Y., Zhao, H., An, Y., Ju, H., & Liu, Y. (2025) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00111 · Cited by 21
Wang, Y., Nan, J., Ma, H., Xu, J., Guo, F., Wang, Y., Liang, Y., Zhang, J., & Zhu, S. (2023) · Nano Letters · doi:10.1021/acs.nanolett.3c00829 · Cited by 20
Lanthanide-dye hybrid luminophores for advanced NIR-II bioimaging
Mei, M., Wu, B., Wang, S., & Zhang, F. (2024) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2024.102469 · Cited by 20
Self-citationStructure Tailoring of Hemicyanine Dyes for In Vivo Shortwave Infrared Imaging
Guo, J., Zhu, Y., Qu, Y., Zhang, L., Fang, M., Xu, Z., Wang, T., Qin, Y., Xu, Y., Li, Y., et al. (2024) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c01662 · Cited by 20
Self-citationLiao, J., Liu, Y., Wu, S., Yang, Z., Zhou, J., Jin, D., & Guan, M. (2021) · Journal of Luminescence · doi:10.1016/j.jlumin.2021.118597 · Cited by 20
Ding, L., Zhang, X., Wang, P., Ke, J., Zhou, Y., Wu, M., Wei, Z., Cao, Y., Li, H., Chen, G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63311-7 · Cited by 19
“39).”
Near-Infrared-II Bioimaging for in Vivo Quantitative Analysis
Yang, S., Tan, X., Tang, L., & Yang, Q. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.763495 · Cited by 18
Novel HER2-Targeted Peptide for NIR-II Imaging of Tumor
Cao, R., Li, R., Shi, H., Liu, H., & Cheng, Z. (2023) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.2c00964 · Cited by 19
Lei, S., Jiang, K., Zhang, C., Sun, W., Pan, Y., Wang, D., Huang, P., & Lin, J. (2023) · Research · doi:10.34133/research.0286 · Cited by 19
“…(NIR-II, 900 to 1,700 nm) window has revolutionized in vivo bioinformatics visualization [11–13], owing to its high sensitivity and spatiotemporal resolution [14–16], being employed in NIR-II FL imaging-guided surgery [17,18], in vivo tracking [19,20], and molecular event monitoring [21,22].”
BackgroundShang, J., Zhang, Y., Cheng, Y., Wang, B., Rong, X., Zhang, Y., Gao, W., & Fang, M. (2023) · Microchemical Journal · doi:10.1016/j.microc.2023.109653 · Cited by 19
Meng, X., Song, J., Du, Z., Tao, Y., & Qi, J. (2025) · ACS Nano · doi:10.1021/acsnano.5c07280 · Cited by 18
Wang, Z., Hao, M., Li, C., Gao, X., Yu, S., Zhao, L., Zhang, H., Li, G., & Li, Y. (2025) · Advanced Materials · doi:10.1002/adma.202512763 · Cited by 19
Self-citationZhao, L., Zhu, H., Duo, Y., Pang, D., Wang, Z., & Liu, S. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301584 · Cited by 18
Self-citationDou, W., Guo, C., Zhu, L., Qiu, P., Kan, W., Pan, Y., Zang, Y., Dong, L., Li, J. X., Tan, Y., et al. (2023) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.3c00078 · Cited by 18
Wu, Z., Chen, H., Zhang, H., Ye, L., Ke, J., Liu, Y., Sun, P., & Hong, M. (2024) · Nano Today · doi:10.1016/j.nantod.2024.102214 · Cited by 18
Self-citationBădescu‐Singureanu, C. C., Nizovtsev, A. S., Pecoraro, V. L., Pètoud, S., & Eliseeva, S. V. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202416101 · Cited by 17
Bioengineered nanomaterials for dynamic diagnostics in vivo
Wu, J., Zhou, X., Tsang, C. Y., Mei, Q., & Zhang, Y. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00136f · Cited by 18
Advances in Near‐Infrared Organic Micro/Nanolasers
Wu, J., Gao, H., Wang, X., Wu, Y., Jiang, L., & Liao, L. (2022) · Advanced Optical Materials · doi:10.1002/adom.202200815 · Cited by 18
Zhang, X., Yang, F., Zhao, X., Wu, Q., He, L., Li, Z., Zhou, Z., Ren, T., Zhang, X., & Yuan, L. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202410666 · Cited by 18
Chen, S., Tang, T., Huang, B., Liu, F., Cui, R., Zhang, M., & Sun, T. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c04005 · Cited by 17
Organic small-molecule NIR-II fluorophores for tumor phototheranostics
Xiang, D., Wang, Z., Zheng, H., Tang, Y., & Li, Q. (2026) · Light: Science & Applications · doi:10.1038/s41377-026-02212-w · Cited by 22
“…NIR-II imaging in 2009, the fi eld has witnessed remarkable progress, leading to the emergence of diverse probe materials, including carbon nanotubes 44,45 , quantum dots 46 – 48 , rare-earth-doped nanoparticles 49 – 51 , conjugated polymers 52 , and organic small-molecule dyes 53 – 58 .”
Self-citationLiu, Y.-T., Zhang, Q.-Q., Li, J., Kuang, G.-Y., Yao, S.-Y., Wang, H., Zou, Y., & Zhao, L.-X. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.143846 · Cited by 16
Advances of Fluorescence Molecular Imaging: NIR‐II Window, Probes, and Tomography
Song, F., Zhang, P., Wu, H., Ma, C., Liu, Z., Cai, R., Feng, Y., He, Y., Dong, X., Tian, Y., et al. (2025) · Laser & Photonics Review · doi:10.1002/lpor.202400275 · Cited by 16
Self-citationDiao, B., Shi, S. Q., Li, J., Yang, L., Zheng, L., Guo, H., & Peng, X. (2025) · Advanced Materials · doi:10.1002/adma.202515813 · Cited by 16
Liu, Z., Yu, Y. F., Kang, W., Chen, F., Yan, F., Ma, B., & Ge, S. (2022) · Composites Part B Engineering · doi:10.1016/j.compositesb.2022.110186 · Cited by 17
Self-citationNaseri, S., Mirzakhani, M., Besnard, C., Guénée, L., Briant, L., Nozary, H., & Piguet, C. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202202727 · Cited by 16
High stability of dark current enables stretchable near-infrared self-powered organic photodetectors
Wang, C., Xiao, M., Qiao, J., Cui, F., Jiang, D., Meng, K., Lian, G., Yin, H., Meng, Z., Hao, X., et al. (2024) · Applied Physics Letters · doi:10.1063/5.0202910 · Cited by 16
Kang, W., Ma, M., Tang, S., Wang, Y., Li, J., Xu, L., Ma, P., Song, D., & Sun, Y. X. (2024) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2024.136299 · Cited by 16
Song, L., & Li, J. (2024) · Small · doi:10.1002/smll.202407787 · Cited by 16
Gao, D., Wang, P., Gao, F., Nguyen, W., & Chen, W. (2022) · Nanomaterials · doi:10.3390/nano12122029 · Cited by 16
Less Is More: Donor Engineering of a Stable Molecular Dye for Bioimaging in the NIR-IIb Window
Wang, T., Qin, Y., Wang, J., Xu, Y., Guo, J., Zhu, Y., Zhang, H., Qin, Y., Qi, Z., Fu, H., et al. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c02866 · Cited by 16
Self-citationNear-infrared theranostics for brain diseases: Design, engineering, and emerging applications
Wang, J., Liu, Y., Qi, C., Luo, Z., Wei, J., Wang, G., Ismail, M., Zhong, Y., & Shi, B. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216591 · Cited by 18
Wu, B., Zhang, L., Yan, K., Mei, M., Wu, W., He, Z., Wang, S., & Zhang, F. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c13688 · Cited by 15
Self-citationDuan, X., Zhang, G., Ji, S., Zhang, Y., Li, J., Ou, H., Gao, Z., Feng, G., & Ding, D. (2022) · Angewandte Chemie · doi:10.1002/ange.202116174 · Cited by 15
Rare Earth-Doped Nanoparticles for Near-Infrared II Image-Guided Photodynamic Therapy
Meng, J., Cui, Y., & Wang, Y. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c02176 · Cited by 17
A TME-enlightened protein-binding photodynamic nanoinhibitor for highly effective oncology treatment
Cui, Z., Huang, B., Zheng, J., Tian, J. H., & Zhang, W. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2321545121 · Cited by 15
“Moreover, it has been also effectively employed in conjunction with erbium (III) for achieving high - resolution NIR II imaging to track cancer cell metastases in the mouse brain (36).”
Self-citationLi, C., Bi, W., Liang, T., Li, Z., & Liu, Z. (2023) · Chemical Science · doi:10.1039/d3sc02338a · Cited by 14
Self-citationBand Gap Engineering Improves Three-Photon Luminescence of Quantum Dots for Deep Brain Imaging
Wang, F., He, M., Huang, B., Tang, T., Liu, F., Cui, R., Qian, J., Zhang, M., & Sun, T. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.3c00845 · Cited by 14
Yang, Y., Sun, C., Wang, S., Yan, K., Zhao, M., Wu, B., & Zhang, F. (2022) · Angewandte Chemie · doi:10.1002/ange.202117436 · Cited by 15
Self-citationDihydroxanthene‐Derived Dioxetane Chemiluminophores for Activatable in Vivo Imaging
Liao, K., Zhang, L., Jiang, J., Wang, F., & Peng, T. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202514236 · Cited by 13
Advanced second near-infrared fluorophores for bioapplications
Bai, Q., Yang, Q., Liu, Y., Li, A., Yin, X.-B., & Wu, S. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217146 · Cited by 14
Zhu, Y., Yan, D., Zhu, J., Xü, H., Zhang, W., Hou, J., Wang, D., & Tang, B. Z. (2025) · ACS Nano · doi:10.1021/acsnano.5c09246 · Cited by 13
Self-citationChen, H., Wu, Z., Ke, J., Li, G., Jiang, F., Liu, Y., & Hong, M. (2022) · Science China Materials · doi:10.1007/s40843-022-2050-1 · Cited by 13
Development and Validation of Nerve-Targeted Bacteriochlorin Sensors
Hernández‐Gil, J., Chow, C. Y., Chatras, H., França, P. D. D. S., Samuels, Z. V., Cornejo, M., King, G. F., Lewis, J. S., Reiner, T., & Gonzales, J. (2023) · Journal of the American Chemical Society · doi:10.1021/jacs.3c02520 · Cited by 13
Zhang, W., Wang, E., Li, X., Huang, W., Sun, Y., Liu, Z., Zheng, W., Yi, X., Li, X., Li, L., et al. (2024) · Advanced Optical Materials · doi:10.1002/adom.202400603 · Cited by 13
Self-citationHan, J., Kim, S., Kang, D., Lee, S.-H., Cho, A. Y., Lee, H., Kwon, J.-H., Shin, Y. M., Kim, Y., & Lee, J. (2025) · ACS Sensors · doi:10.1021/acssensors.4c03202 · Cited by 13
Wang, S., Liang, H., Yang, Z., Wang, Z., Yang, B., & Lu, C. (2024) · RSC Advances · doi:10.1039/d4ra03242j · Cited by 12
Self-citationAdvances in Lanthanide‐Based NIR‐IIb Probes for In Vivo Biomedical Imaging
Wu, J., Chen, Z., Xie, Y., & Fan, Y. (2024) · Small Methods · doi:10.1002/smtd.202401462 · Cited by 12
Self-citationSize‐Controlled Self‐Assembly for Bimodal In Vivo Imaging
Albers, A., Kuberasivakumaran, S., Fernández, Z., Daniliuc, C. G., Li, Y., Lee, M., Geyer, C., Hoffmann, E., Faber, C., Helfen, A., et al. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202500144 · Cited by 13
Lathion, T., Bourseguin, J., Eliseeva, S. V., Zeller, M., Pètoud, S., & Pecoraro, V. L. (2025) · Chemical Science · doi:10.1039/d5sc01320h · Cited by 12
Chen, P., Li, D., Li, Z., Pi, L., Xu, X., Wang, H., Zhou, X., & Zhai, T. (2022) · Advanced Optical Materials · doi:10.1002/adom.202102562 · Cited by 12
Review—Exploring Technological Innovations of Doped Rare Earth Materials
Farooq, M., Nazir, I., Rafiq, H., & Rasool, M. H. (2023) · ECS Journal of Solid State Science and Technology · doi:10.1149/2162-8777/acccac · Cited by 12
Sun, L., Huang, Y. D., Ji, C., Grimes, C. A., & Cai, Q. (2023) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2023.133669 · Cited by 12
Yu, H., Ai, L., & Lu, S. (2026) · Chem · doi:10.1016/j.chempr.2025.102867 · Cited by 13
Tandem Auxochrome Design Enables Ready Access to Deep Shortwave Infrared Dyes
Yan, K., Zeng, Z., Liu, H., Zhang, L., Dong, Y., Chen, Z., Wang, S., & Zhang, F. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.6c02935 · Cited by 11
Self-citationDing, Q., Zhao, J., Zhang, H., Li, C., Sun, M., Chen, C., Lin, H., Xu, C., Kuang, H., & Xu, L. (2022) · Angewandte Chemie · doi:10.1002/ange.202210370 · Cited by 11
Self-citationLiu, Y., Gu, M., Ding, Q., Zhang, Z., Gong, W., Yuan, Y., Miao, X., Ma, H., Hong, X., Hu, W., et al. (2022) · Angewandte Chemie · doi:10.1002/ange.202214875 · Cited by 11
Kovalenko, A., Eliseeva, S. V., Collet, G., Abdellaoui, S. E., Natkunarajah, S., Lerondel, S., Guénée, L., Besnard, C., & Pètoud, S. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.4c03406 · Cited by 11
Zhang, C., Wu, Y., Zeng, F., Wen, Y., Chen, J., Deng, G., Zhang, L., Zhao, S., Wu, S., & Zhao, Y. (2024) · Angewandte Chemie · doi:10.1002/ange.202406694 · Cited by 11
Multiplexed Shortwave Infrared Imaging Highlights Anatomical Structures in Mice
Zhong, X., Patel, A., Sun, Y., Saeboe, A. M., & Dennis, A. M. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202410936 · Cited by 12
Chen, Z., Wang, X., Yang, M., Ming, J., Yun, B., Zhang, L., Wang, X., Yu, P., Xu, J. M., Zhang, H., et al. (2023) · Angewandte Chemie · doi:10.1002/ange.202311883 · Cited by 11
Self-citationMultifunctional fiber-optic theranostic probe for closed-loop tumor photothermal therapy
Li, Z., Li, Z., Cheng, Z., Borri, C., Giannetti, A. E., Lan, N., Long, J., Chen, W., Cai, X., Yang, J., et al. (2026) · Light Science & Applications · doi:10.1038/s41377-026-02219-3 · Cited by 11
“…monitoring of multiple parameters is crucial for investigating pathophysiological processes regulated by complex biological interactions 51 – 53 , the functional capacity of a single optical fi ber can be further enhanced by fully leveraging the spectral resources and employing multipeak fi…”
Wang, H., Yu, Z., Wang, Y., Zhu, H., Liu, L., Wang, S., Li, D., & Dou, J. (2024) · Dyes and Pigments · doi:10.1016/j.dyepig.2024.111962 · Cited by 10
Self-citationZheng, J., Meng, W., Chen, S., Cui, Z., Xian, X., Tian, J. H., Krysko, D. V., Li, B., & Zhang, W. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.06.024 · Cited by 12
Self-citationXu, R., Cao, H., Yang, Y., Han, F., Lin, D., Chen, X., Wu, C., Liu, L., Yu, B., & Qu, J. (2024) · ACS Nano · doi:10.1021/acsnano.4c14468 · Cited by 10
Wu, L., Li, Y., Xiang, X., Qin, H., Zhao, J., Zhai, X., Li, P., & Li, Z. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.161376 · Cited by 10
Kang, D., Kim, S., Goh, Y., Kim, M., Lee, S.-H., Kwon, J.-H., Nam, S. H., & Lee, J. (2025) · Light Science & Applications · doi:10.1038/s41377-025-01882-2 · Cited by 10
“Near-infrared (NIR)-based optical technologies have emerged as promising tools in biomedical research because they enable real-time and highly sensitive monitoring of biomolecular interactions and high-resolution imaging in biological environments 1 – 6 .”
Tm 3+ heavily doped NIR-III bioprobe with 1 µm Stokes shift towards deep-tissue applications
Zhang, S., Li, J., Zhou, Z., Zhu, Y., Ning, D., Ren, J., Liu, L., & Zhang, J. (2021) · Optics Express · doi:10.1364/oe.444595 · Cited by 9
Liu, G., Xin, X., Zhuang, H., Wu, X., Su, D., Guo, Q., & Shi, W. Q. (2024) · Molecular Physics · doi:10.1080/00268976.2023.2301387 · Cited by 9
Guo, C., Xiong, X., Zhao, X., Li, Y., Li, S., Xu, S., James, T. D., & Wang, L. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c14715 · Cited by 9
Recent Advances in NIR-II Molecular Aggregates and Applications in the Biomedical Field
Wu, K., Yang, R., Song, X., Ju, H., & Liu, Y. (2025) · Chemosensors · doi:10.3390/chemosensors13020067 · Cited by 9
Sun, Y., Yan, X., Wang, D., Zhu, J. Z., Su, H., Zhu, D., Yan, D., & Tang, B. Z. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00590 · Cited by 9
Qin, Y., Guo, J., Qin, Y., Xu, Z., Fang, M., Fu, H., Cui, M., & Zhou, K. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c04745 · Cited by 10
Yang, Y., Zhang, H., Yáng, Z., & Huang, W. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217598 · Cited by 11
Self-citationYin, J., Zheng, H., Zhang, W., Shen, L., Lai, R., Tian, L., Zhao, F., & Shao, Y. (2022) · Optics Express · doi:10.1364/oe.465486 · Cited by 9
Self-citationDas, R. S., Mukherjee, A., Kar, S., Bera, T., Das, S., Sengupta, A., & Guha, S. (2022) · Organic Letters · doi:10.1021/acs.orglett.2c02114 · Cited by 9
Nonlight-Driven Aggregation-Induced Emission Luminogens for Bioimaging and Theranostics
Tian, Y., Huang, W., Sheng, Z., Yan, D., Wang, D., & Tang, B. Z. (2025) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00108 · Cited by 8
Li, M., Gao, J., Xie, Y., Zhu, Z., Huang, L., Lai, Y., Yar, M., Bajda, M., Li, M., Yu, H., et al. (2025) · Angewandte Chemie International Edition · doi:10.1002/anie.202508646 · Cited by 9
Self‐Luminous Probe with One‐Step Energy Conversion from Bioluminescence to NIR‐IIb
Jiang, Z. L., Yang, Z., & Li, W. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202302089 · Cited by 8
Recent Progress in Peptide-Based Molecular Probes for Disease Bioimaging
Xu, Y., Chen, J., Zhang, Y., & Zhang, P. (2024) · Biomacromolecules · doi:10.1021/acs.biomac.3c01413 · Cited by 8
Enhancing NIR-II luminescence of erbium sublattice through lanthanide-mediated energy modulation
Hu, Z., Huang, J., Yan, L., & Zhou, B. (2022) · Optik · doi:10.1016/j.ijleo.2022.169037 · Cited by 8
Li, J., Lou, K., Dang, Y., Tian, H., Luo, Q., Huang, C., Liu, R., Gong, X., Wang, S., Liu, H., et al. (2023) · Materials & Design · doi:10.1016/j.matdes.2023.111703 · Cited by 9
Self-citationMultimodal Contrast Agents for Optoacoustic Brain Imaging in Small Animals
Shi, X., Ji, B., Kong, Y., Guan, Y., & Ni, R. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.746815 · Cited by 8
“Na et al. (2021); Na and Wang (2021) recently demonstrated the first OA imaging in a living human brain.”
BackgroundHarnessing NIR-II luminescence in ultrasmall gold nanoparticles for enhanced biomedical applications
Zhou, T., & Li, Z. (2024) · Science China Materials · doi:10.1007/s40843-024-3187-8 · Cited by 8
Stec, G. J., & Wilson, J. J. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216764 · Cited by 9
Biomaterials for biomarker imaging and detection
Wang, Y., Huang, X., Wu, G., Wu, W., Li, S., Su, C., Li, L., & Lv, Q. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.07.049 · Cited by 10
“5 from the liver and spleen are shown alongside EB766 images of the gastrointestinal tract; these representative images were replicated across three biologically independent mice [120].”
Lathion, T., Eliseeva, S. V., Pètoud, S., & Pecoraro, V. L. (2025) · Inorganic Chemistry · doi:10.1021/acs.inorgchem.5c03669 · Cited by 7
Metadata
- Authors
- Wang, T., Wang, S., Liu, Z., He, Z., Yu, P., Zhao, M., Zhang, H., Lu, L., Wang, Z., Wang, Z., Zhang, W., Fan, Y., Sun, C., Zhao, D., Liu, W., Bünzli, J.-C. G., & Zhang, F.
- Affiliations
- Fudan University (CN)
- East China University of Science and Technology (CN)
- ShanghaiTech University (CN)
- École Polytechnique Fédérale de Lausanne (CH)
- Corresponding author
- Wang, Shangfeng
- Zhang, Weian
- Zhang, Fan
- ORCID
- Venue
- Nature Materials
- Published
- 2021-07-29
- Volume
- 20
- Issue
- 11
- Pages
- 1571-1578
- ISSN
- 1476-1122 (ISSN-L)
- 1476-4660
- OpenAlex
- W3186280068
- Cited by
- 308
- References
- 46
- Citations by year
- 2026: 41 · 2025: 71 · 2024: 64 · 2023: 59 · 2022: 58 · 2021: 15
- FWCI
- 14.87
- Type
- journal article
- Language
- en
- Open access
- green
- infoscience.epfl.ch
- Licence
- Locations
- Nature Materials (publishedVersion)
- PubMed (publishedVersion)
- Infoscience (Ecole Polytechnique Fédérale de Lausanne) (submittedVersion, cc-by-nc-nd)
- Funders
- China Postdoctoral Science Foundation (KLH1615200, KLH1615215)
- National Natural Science Foundation of China (22088101, 21725502, 51961145403, 21904023)
- Ministry of Science and Technology of the People’s Republic of China (2017YFA0207303)
- Science and Technology Commission of Shanghai Municipality (20JC1411700, 19490713100, 20490710600, 20S31903700)
- Topics
- Physical Sciences › Materials Science › Materials Chemistry › Lanthanide and Transition Metal Complexes
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Keywords
- erbium(III) complexes, bacteriochlorins, near-infrared fluorescence, Stokes shift, energy transfer, deep tissue imaging, fluorescence-guided surgery, brain metastasis imaging, intravital microscopy
- MeSH terms
- Animals, Erbium, Fluorescent Dyes, Porphyrins, Spectroscopy, Near-Infrared
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
