The DOI matches its Crossref record; 982 of the 982 references it cites were found in a registry or an index.
Drug-induced liver injury
Open accessAbstract
Drug-induced liver injury (DILI) is an adverse reaction to drugs or other xenobiotics that occurs either as a predictable event when an individual is exposed to toxic doses of some compounds or as an unpredictable event with many drugs in common use. Drugs can be harmful to the liver in susceptible individuals owing to genetic and environmental risk factors. These risk factors modify hepatic metabolism and excretion of the DILI-causative agent leading to cellular stress, cell death, activation of an adaptive immune response and a failure to adapt, with progression to overt liver injury. Idiosyncratic DILI is a relative rare hepatic disorder but can be severe and, in some cases, fatal, presenting with a variety of phenotypes, which mimic other hepatic diseases. The diagnosis of DILI relies on the exclusion of other aetiologies of liver disease as specific biomarkers are still lacking. Clinical scales such as CIOMS/RUCAM can support the diagnostic process but need refinement. A number of clinical variables, validated in prospective cohorts, can be used to predict a more severe DILI outcome. Although no pharmacological therapy has been adequately tested in randomized clinical trials, corticosteroids can be useful, particularly in the emergent form of DILI related to immune-checkpoint inhibitors in patients with cancer.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The vast majority of cases of DILI occur at therapeutic doses in a small proportion of individuals exposed to the drug, representing an idiosyncratic reaction, and therefore unpredictable based on the drug's mechanism of action and related to the uniqueness of the individual [1,2].”
From DILI Differences and Similarities between the US and Europe (2026) · cites this paper as [1]
In the citing paper
“Drug-induced liver injury (DILI) is an uncommon adverse reaction to drugs, and other chemicals, including herbal and dietary supplements (HDS).”
From DILI Differences and Similarities between the US and Europe (2026) · cites this paper as [1]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cited works that were retracted
Works this paper cites that were later retracted, from the retraction notices publishers deposit. Major when the notice came out before this paper was published.
Rated major: it would touch a result — a value a result rests on, reported and recomputed p-values on opposite sides of the significance level, two passages that conflict with no sign which is right, or a cited work retracted before this paper was published.
Cited work 10.1128/aac.04976-14 · retracted 2015-12-28 · notice 10.1128/aac.04976-14 · this paper published 2019-08-22
Rated major: it would touch a result — a value a result rests on, reported and recomputed p-values on opposite sides of the significance level, two passages that conflict with no sign which is right, or a cited work retracted before this paper was published.
In the paper
“Francis, B. et al. Temporary removal: reference intervals for putative biomarkers of drug-induced liver injury and liver regeneration in healthy human volunteers. J. Hepatol. https://doi.org/10.1016/j.jhep.2018.04.024 (2018).”
Cited work 10.1016/j.jhep.2018.04.024 · retracted 2018-05-03 · notice 10.1016/j.jhep.2018.04.024 · this paper published 2019-08-22
Citations
Cites
2 retracted
Francis, B., Clarke, J. I., Walker, L. E., Brillant, N., Jorgensen, A., Park, B. K., Pirmohamed, M., & Antoine, D. J. (2018) · Journal of Hepatology · doi:10.1016/j.jhep.2018.04.024 · Cited by 4
RetractedAhrens, J. H., & Sastic, C. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04976-14 · Cited by 3
Retracted(1992) · PubMed · Cited by 33,716
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
Kerr, J. F. R., Wyllie, A. H., & Currie, A. R. (1972) · British Journal of Cancer · doi:10.1038/bjc.1972.33 · Cited by 15,673
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
Hodi, F. S., O'Day, S. J., McDermott, D. F., Weber, R. W., Sosman, J. A., Haanen, J. B., Gonzalez, R., Robert, C., Schadendorf, D., Hassel, J. C., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1003466 · Cited by 15,155
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., & Wang, X. (1997) · Cell · doi:10.1016/s0092-8674(00)80434-1 · Cited by 7,289
Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672
Manns, M. P., McHutchison, J. G., Gordon, S. C., Rustgi, V. K., Shiffman, M. L., Reindollar, R., Goodman, Z. D., Koury, K. J., Ling, M.-H., & Albrecht, J. K. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06102-5 · Cited by 6,027
Research works printed but not linked: 3
- Institute of Medicine. Exploring the Biological Contributions to Human Health: Does Sex Matter? (National Academies Press, 2001).
- Sanjuan-Jimenez, R. et al. Prevalence of hepatitis E markers in Spanish patients with suspected drug-induced liver injury [abstract]. Hepatology 66, 423A (2017).
- Abu-Sbeih, H., Styskel, B., Blechazz, B., Chalasani, N. & Miller, E. Clinically significant hepatotoxicity due to immune checkpoint inhibitors is rare but leads to treatment discontinuations in high proportion. Hepatology 68, 25A (2018).
Cited by
Sorted by citations
Items 401–500 of 922
Cheng, R., Muneer, A., Hercher, M., Bajrami, B., & Nemati, R. (2025) · SLAS TECHNOLOGY · doi:10.1016/j.slast.2025.100307 · Cited by 7
Bobat, F., Wu, D. B.-C., Tu, E., Kapoor, D., Sharma, P. K., Adams, J. S., Orameh, C., Yadavalli, T., Date, A. A., & Shukla, D. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1621590 · Cited by 7
Bioactive Herbs for Liver Disorders: A Phyto-Pharmacological Review
Sahu, P., & Satapathy, T. (2025) · Current Drug Metabolism · doi:10.2174/0113892002381436250721200746 · Cited by 7
Role of metabolic nuclear receptors in acute liver injury and drug-induced hepatotoxicity
Nie, L., Yan, N., Gonzalez, F. J., Hao, H., & Yan, T. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107942 · Cited by 7
CD47: an immunoregulatory nexus in liver and gastrointestinal disorders
Otuagomah, J., Newcomb, A., Gwag, T., & Wang, S. (2025) · eGastroenterology · doi:10.1136/egastro-2025-100242 · Cited by 7
Mao, X., Hu, X., & Fang, J. (2025) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2025.1737234 · Cited by 7
Zhang, Y., Jin, Z., Xu, L., Zhong, Z., Wang, X., Gao, C., & Li, L. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.12.016 · Cited by 7
Machine Learning for Predicting Stroke Risk Stratification Using Multiomics Data: Systematic Review
Yoo, H. Y., Shin, H., Kim, E. E., & Son, Y.-J. (2026) · Journal of Medical Internet Research · doi:10.2196/85654 · Cited by 7
Piva, M., Martelossi-Cebinelli, G., Mendes-Pierotti, S., Chinen, W. H., Cardines, P. H. F., Martinez, R. M., Georgetti, S. R., Baracat, M. M., Vicentini, F. T. M. C., Verri, W. A., Jr., et al. (2026) · Foods · doi:10.3390/foods15122159 · Cited by 7
Xiang, H., Li, Y., Cheng, X., He, B., Li, H.-M., Zhang, Q., Wang, B., & Wen-xing, P. (2023) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2023.116635 · Cited by 7
Huang, A., Zhu, Y., Liu, S., Sun, Y. H., Liu, Z., Liang, Q., Zhao, J., Chang, B., Bi, J., Liu, J., et al. (2024) · Liver International · doi:10.1111/liv.15899 · Cited by 7
Self-citationReview of Hydrogen Sulfide Based on Its Activity Mechanism and Fluorescence Sensing
Zhang, J., Jing, Q., Gao, F., Zhang, F., Pei, D., Di, D., & Hai, J. (2024) · Targets · doi:10.3390/targets2030012 · Cited by 7
High-Throughput Assessment of Bile Salt Export Pump Inhibition Using RapidFire-MS and DESI-MS
Li, J., Morato, N. M., Westover, L., Abeywickrema, P. D., Geng, J., Piassek, M., Harden, D., Strambeanu, I. I., Shi, Z., Cooks, R. G., et al. (2024) · ACS Medicinal Chemistry Letters · doi:10.1021/acsmedchemlett.4c00302 · Cited by 7
Ye, M., Shen, Y., Xiao, Z., Li, Y., Zhang, Q., Lan, Y., Zhu, C., & Zhou, Y. Y. (2024) · Analytica Chimica Acta · doi:10.1016/j.aca.2024.343122 · Cited by 7
Yang, Y., Chen, Q., Liu, Z., Huang, T., Hong, Y., Li, N., Ai, K., & Huang, Q. (2024) · Journal of Colloid and Interface Science · doi:10.1016/j.jcis.2024.08.239 · Cited by 7
Ge, T., Wang, Y., Han, Y., Bao, X., & Chunfeng, L. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-024-01611-3 · Cited by 7
Xiang, T., Lin, S., Tang, B., Zhang, H., Luan, J., Qu, Y., Wang, K., Wu, W., Shen, Z., Ma, W., et al. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.112833 · Cited by 7
Epigenetic modifications in drug‐induced liver injury: A systematic review
Santos‐Fernández, R. L. D. L., Segovia‐Zafra, A., Paz‐López, G., Matilla‐Cabello, G., Niu, H., Álvarez‐Álvarez, I., Stephens, C. M., Gonzalez-Jimenez, A., Lucena, M. I., Andrade, R. J., et al. (2025) · British Journal of Clinical Pharmacology · doi:10.1002/bcp.70053 · Cited by 7
Self-citationTreatment of Insomnia With Traditional Chinese Medicine Presents a Promising Prospect
Zhang, B., Wang, Q., Zhang, Y., Wang, H., Kang, J., Zhu, Y., Wang, B., & Feng, S. (2025) · Phytotherapy Research · doi:10.1002/ptr.8495 · Cited by 9
Li, J., Li, W., Wang, S., Zheng, H., Bao, J., Wang, Y., & Jin, H. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119916 · Cited by 7
Quantitative Systems Toxicology and Drug Development: The DILIsym Experience
Watkins, P. B. (2022) · Methods in molecular biology · doi:10.1007/978-1-0716-2265-0_9 · Cited by 7
Self-citationLiu, L., Yang, Y., Li, W., Li, Y., Jiang, X., & Wang, L. (2022) · Human & Experimental Toxicology · doi:10.1177/09603271221097365 · Cited by 7
Wang, Y., Charkoftaki, G., Davidson, E. A., Orlicky, D. J., Tanguay, R. L., Thompson, D. C., Vasiliou, V., & Chen, Y. (2022) · Current Opinion in Environmental Science & Health · doi:10.1016/j.coesh.2022.100389 · Cited by 7
Yu, D., Shao, Z., Fu, Y., Tang, X., Chen, Q., & Deng, Z. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1015008 · Cited by 7
Role of oxidative stress and endoplasmic reticulum stress in drug-induced liver injury
Wu, H., Bao, X., Gutierrez, A. H., Nevzorova, Y. A., & Cubero, F. J. (2023) · Exploration of Digestive Diseases · doi:10.37349/edd.2023.00020 · Cited by 8
Age-dependent immune responses in COVID-19-mediated liver injury: focus on cytokines
Aghamohamadi, N., Shahba, F., Mehrabadi, A. Z., Khorramdelazad, H., Karimi, M., Falak, R., & Emameh, R. Z. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1139692 · Cited by 7
FakhriRavari, A., & Malakouti, M. (2024) · Pharmacoepidemiology · doi:10.3390/pharma3010005 · Cited by 7
Fettiplace, A., Matis‐Mitchell, S., Molodetskyi, O., Söderbergh, M., Oscarsson, J., Lin, M., Ravikiran, S., Billger, M. A., & Ambery, P. (2024) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2024.2328816 · Cited by 7
The Role of Eosinophils in Liver Disease
Xie, L., Zhang, H., & Xu, L. (2024) · Cellular and Molecular Gastroenterology and Hepatology · doi:10.1016/j.jcmgh.2024.101413 · Cited by 7
Cheli, S., Torre, A., Schiuma, M., Montrasio, C., Civati, A., Galimberti, M., Battini, V., Mariani, I., Mosini, G., Carnovale, C., et al. (2024) · Clinical Infectious Diseases · doi:10.1093/cid/ciae583 · Cited by 7
Saeed, B. I., Uthirapathy, S., Kubaev, A., Ganesan, S., Shankhyan, A., Gupta, S., Joshi, K. K., Kariem, M., Jasim, A. S., & Ahmed, J. K. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04115-w · Cited by 7
Sipos, M., Farcas, A. M., Leucuta, D., Bucșa, C., Hurubă, M., & Mogoșan, C. (2021) · Pharmaceuticals · doi:10.3390/ph14050441 · Cited by 7
Ore, A., Adeogun, A. I., & Akinloye, O. A. (2021) · Medicines · doi:10.3390/medicines9010001 · Cited by 7
Newly identified genetic variants associated with idiosyncratic drug-induced liver injury
Stolz, A. (2022) · Current Opinion in Gastroenterology · doi:10.1097/mog.0000000000000822 · Cited by 7
Immune-Related Adverse Events of Cancer Immunotherapies Targeting Kinases
Ramos‐Casals, M., Flores-Chávez, A., Brito‐Zerón, P., Lambotte, O., & Mariette, X. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108250 · Cited by 7
Transporters for Bile Formation in Physiology and Pathophysiology
Stieger, B. (2022) · CHIMIA International Journal for Chemistry · doi:10.2533/chimia.2022.1025 · Cited by 7
Liu, A., Han, N., Munoz-Muriedas, J., & Bender, A. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010148 · Cited by 7
Xiong, Y.-T., Wang, J.-F., Li, L., Bai, Z.-F., Liu, Y., Huang, A., Wang, K.-X., Fu, Y., Yang, W., Guo, C., et al. (2024) · iLIVER · doi:10.1016/j.iliver.2024.100095 · Cited by 6
Zhang, B., Zheng, T., Chen, M., Fang, Q., Zhang, Q., Chen, S., Hao, T., Wang, X., & Yuan, M. (2025) · Aquatic Toxicology · doi:10.1016/j.aquatox.2025.107584 · Cited by 6
Wei, X., Wang, H., Sun, X., Huang, X., Xu, W., Liang, Y., Liu, L., Mo, S., Lin, X., & Lin, J. (2020) · PubMed Central · Cited by 6
Osimertinib‐related liver injury with successful osimertinib rechallenge: A case report
Cheng, Y., Chang, W., Yen, H., Peng, Y., Chang, W., & Chang, P. (2022) · Thoracic Cancer · doi:10.1111/1759-7714.14556 · Cited by 6
Pavlović, R. Z., Finnegan, T. J., Metlushko, A., Hansen, A. L., Waudby, C. A., Wang, X., Hoefer, N., McComb, D. W., Pavić, A., Plačkić, N., et al. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202303374 · Cited by 6
Drug-Induced Liver Injury Due to Doxycycline: A Case Report and Review of Literature
Nikolajevic, N., Nikolajevic, M., Pantić, I., Korica, B., Kotseva, M., Alempijevic, T. M., Jevtic, D., Madrid, C., & Dumic, I. (2024) · Cureus · doi:10.7759/cureus.59687 · Cited by 6
Zeng, J., Wu, W., Gao, H., Li, M., Zhou, B., Mo, Y., Guan, Y., Qi, T., Wu, X., Liu, D., et al. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.119520 · Cited by 6
Forsythiaside A Reduces Acetaminophen Hepatotoxic Metabolism by Inhibiting Pregnane X Receptor
Pu, S., Pan, Y., Wang, Z., huimin, L., jianhui, Z., Zhang, Q., & Wang, M. (2025) · Molecules · doi:10.3390/molecules30051187 · Cited by 6
Lemke, J., Mengers, N., Schmidt, L., Schulig, L., König, S., Rosendahl, P., Bartz, F., Garscha, U., Bednarski, P. J., & Link, A. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c03112 · Cited by 6
Negi, C. K., Sakolish, C., Tsai, H.-H. D., Nitsche, K. S., Gang, H., Bajaj, P., Ferguson, S., Stanko, J. P., Hewitt, P. G., Kukla, D. A., et al. (2025) · ACS Pharmacology & Translational Science · doi:10.1021/acsptsci.5c00554 · Cited by 6
Gonzalez-Jimenez, A., Suzuki, A., Chen, M., Ashby, K., Álvarez‐Álvarez, I., Andrade, R. J., & Lucena, M. I. (2021) · Archives of Toxicology · doi:10.1007/s00204-021-03013-3 · Cited by 6
Self-citationLiu, Z., Li, T., Connor, S., Thakkar, S., Roberts, R. A., & Tong, W. (2022) · Briefings in Bioinformatics · doi:10.1093/bib/bbac237 · Cited by 6
Autoimmunity associates with severity of illness in elderly patients with drug-induced liver injury
Xiong, Y., Wang, J., Niu, X.-X., Fu, Y., Wang, K., Wang, C., Li, Q., Wang, J., Zhao, J., & Ji, D. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1071709 · Cited by 6
Liraglutide and Liver Injury: Rare Case Report with Literature Review
Salehi, A. M., Hasanzarrini, M., Salehi, H., & Jenabi, E. (2023) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/0118715303180615231011053011 · Cited by 6
Smart Persistent Luminescence Imaging for Early Diagnosis of Drug-Induced Liver Injury
Zhang, F., Song, L., Ye, L., Yang, Z., Shi, J., Yuan, Q., & Zhang, Y. (2024) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00056 · Cited by 6
Tang, S., Yan, G., Kong, L. D., Sun, H. J., Liu, C., Han, Y. M., & Wang, X. (2025) · Acupuncture and Herbal Medicine · doi:10.1097/hm9.0000000000000160 · Cited by 6
Yen, N. T. H., Park, S., Thu, V. T. A., Phat, N. K., Cho, Y., Yoon, S., Shin, J., Kim, D., Oh, J., & Long, N. P. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120801 · Cited by 6
Tang, P., Wu, H., Wang, M., Wang, Y., Zhang, R., Zhang, X., Li, X., Liang, B., & Xiao, W. (2023) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2023.113489 · Cited by 6
Okumura, A., Aoshima, K., & Tanimizu, N. (2024) · Regenerative Therapy · doi:10.1016/j.reth.2024.05.020 · Cited by 6
Wang, J., Qiao, W., Zhao, H., Cheng, J., Han, Y. M., & Yang, X. H. (2020) · New Journal of Chemistry · doi:10.1039/d0nj04029k · Cited by 6
Foltin, E., & Keller, K. A. (2021) · Journal of Herpetological Medicine and Surgery · doi:10.5818/jhms-d-21-00026.2 · Cited by 6
A case of drug-induced acute liver failure caused by corticosteroids
Kajiwara, A., Kawamura, Y., Kinowaki, K., Muraishi, N., Iritani, S., Akuta, N., Fujiyama, S., Sezaki, H., Hosaka, T., Saitoh, S., et al. (2022) · Clinical Journal of Gastroenterology · doi:10.1007/s12328-022-01661-1 · Cited by 6
Gai, Z., Samodelov, S. L., Alecu, I., Hornemann, T., Grove, J. I., Aithal, G. P., Visentin, M., & Kullak-Ublick, G. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24033013 · Cited by 6
Self-citationIzawa, T., Travlos, G. S., Cortes, R. A., Clayton, N. P., Sills, R. C., & Pandiri, A. R. (2023) · Toxicologic Pathology · doi:10.1177/01926233231171101 · Cited by 6
Sacubitril/valsartan-induced liver injury: A case report and literature review
Zhang, T., Cai, J.-L., & Yu, J. (2023) · Medicine · doi:10.1097/md.0000000000034732 · Cited by 6
Glucocorticoid efficacy and treatment strategies for drug-induced liver injury: a literature review
Wang, P., Guo, G., Jiang, S., Ding, D., Yang, J., Lu, Y., Han, Y., & Zhou, X. (2024) · Molecular Biology Reports · doi:10.1007/s11033-024-09806-w · Cited by 5
Abdel-Wahhab, M. A., El‐Nekeety, A. A., Hassan, M. A., Abdel‐Aziem, S. H., & Hassan, N. S. (2025) · Food & medicine homology. · doi:10.26599/fmh.2026.9420088 · Cited by 5
Thakur, G. S., Gupta, A. K., Pal, D., Vaishnav, Y., Kumar, N., Annadurai, S., & Jain, S. K. (2025) · Frontiers in Chemistry · doi:10.3389/fchem.2025.1543075 · Cited by 5
Cheng, Y., Yang, Y., Su, Y., Chen, R., Qian, D., & Xu, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-99669-3 · Cited by 5
Kong, L., Wang, L., Jing, S., Wang, J., Leung, C., & Wang, W. (2025) · Analytica Chimica Acta · doi:10.1016/j.aca.2025.344327 · Cited by 5
Wu, J., Jia, B., Gong, S., Li, Y., Wang, J., Huang, Y., & Guo, J. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1583334 · Cited by 5
Orally deliverable biomimetic nucleic acid therapies for targeted treatment of atherosclerosis
Li, C., Chen, Y., Li, Y., Liu, H., Yang, S., Lin, Y., Qi, Y., Han, S., Dou, Y., Luo, G., et al. (2025) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2025.07.039 · Cited by 5
Zhang, Y., Yang, X.-M., Jin, Q., Chen, J.-Y., Zhu, N.-B., Ju, Y., Lin, Z., Yang, Z., Dong, Y.-N., Li, C., et al. (2025) · Acta Pharmacologica Sinica · doi:10.1038/s41401-025-01622-7 · Cited by 5
Korkmaz, A., Ünsal, V., Yıldız, R., Öner, E., & Atasoy, A. F. (2025) · Scientific Reports · doi:10.1038/s41598-025-18144-1 · Cited by 5
Jin, Z., Cheng, S., Liu, B., Liu, Y., Wei, Y., Hao, X., & Li, H. (2025) · Toxicology Letters · doi:10.1016/j.toxlet.2025.111740 · Cited by 5
Matrine in Liver Diseases: Mechanistic Insights and Therapeutic Potential
Wen, W., Xia, J., Liu, G., & Wang, C. (2026) · Drug Design Development and Therapy · doi:10.2147/dddt.s577265 · Cited by 5
Therapeutic potential of isothiocyanates by targeting the NRF2 pathway
García‐Yagüe, Á. J., Cazalla, E., & Cuadrado, A. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.03.029 · Cited by 5
Usefulness of plasma bile acid profile as a prognostic biomarker for drug-induced liver injury
Monte, M. J., Tran, T. D., Grove, J. I., Li, D., Stephens, C. M., Lucena, M. I., Andrade, R. J., Weber, S., Gerbes, A. L., Bjornsson, E. S., et al. (2026) · EBioMedicine · doi:10.1016/j.ebiom.2026.106229 · Cited by 5
Self-citationVoriconazole-Induced Hepatotoxicity Concise up-to-date review
Ertem, Ö., & Gümüştekin, M. (2022) · Journal of Basic and Clinical Health Sciences · doi:10.30621/jbachs.1051669 · Cited by 5
Zeng, Z., Yi, W., Dong, J.-P., Chen, Q., Sun, F., Lu, H., Lin, Y., Bi, X., Yang, L., Lu, Y., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.962480 · Cited by 5
Qin, Y., Tan, J., Han, X., Wang, N., Zhai, X., & Lu, Y. (2023) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b23-00580 · Cited by 5
Oladejo, D. O., Dokunmu, T. M., Tebamifor, M. E., Bella-Omunagbe, M., Okafor, E., & Iweala, E. (2024) · Scientific African · doi:10.1016/j.sciaf.2024.e02194 · Cited by 5
The role of exosomal lncRNAs in acetaminophen-induced induced liver injury in SD rats
Yang, Z., Shi, L., Zheng, M., Hou, M., Zhou, M., Su, N., Lang, H., Zhao, L., Gu, M., Tang, N., et al. (2024) · Non-coding RNA Research · doi:10.1016/j.ncrna.2024.05.011 · Cited by 5
Catechin ameliorates hepatocellular damage caused by coadministration of isoniazid and rifampicin
Sahu, S., Paul, N., Ganeshpurkar, A., Dubey, N., & Ganeshpurkar, A. (2024) · Advances in Redox Research · doi:10.1016/j.arres.2024.100107 · Cited by 5
Artificial intelligence in drug discovery: Current applications and future directions
Alanazi, A. A. A., Fahad, . I. A. A., Almorshed, A. S. A., Alrbian, A. A. M., Alnughaymishi, A. A. S., Al-Mutairi, N. H. B., Alajmi, A. A., & Otaibi, S. G. A. (2022) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns10.15290 · Cited by 5
The protective effect of the vagus nerve-α7nAChR-IL-22 pathway on acute liver injury
Song, Z., Wu, J., Jiang, T., He, R., & Wen, H. Y. (2024) · Cytokine · doi:10.1016/j.cyto.2024.156840 · Cited by 5
Geometrically constrained cytoskeletal reorganisation modulates DNA nanostructures uptake
Elblová, P., Andělová, H., Lunová, M., Anthi, J., Henry, S. J. W., Tu, X., Dejneka, A., Jirsa, M., Stephanopoulos, N., & Lunov, O. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00074b · Cited by 6
Wang, X., Chen, X., Ji, H., Han, A., Wu, C., Jiang, J., Nie, Y., Li, C., & Zhou, X. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s502850 · Cited by 5
Xiang, S., & Yang, D. K. (2025) · Nutrients · doi:10.3390/nu17060966 · Cited by 5
Tao, X., Zhang, W., Chen, L., Lu, S., Li, Z., Gao, Y., Fan, Q., Li, J., Wu, J., & Zhao, C. (2025) · Toxicon · doi:10.1016/j.toxicon.2025.108366 · Cited by 5
Chen, C., Qian, J., Zhao, X., Han, X., Tang, X., Gao, J., Liu, Y., Jiang, J., & Wen, B. (2022) · Biomedical Chromatography · doi:10.1002/bmc.5469 · Cited by 5
Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
Maillard, M., Arellano, C., Vachoux, C., Chevreau, C., Cabaton, N. J., Pont, F., Saint‐Laurent, N., Lafont, T., Chatelut, É., & Thomas, F. (2022) · Metabolites · doi:10.3390/metabo12090852 · Cited by 5
Ochieng, P. J., Hussain, A., Dombi, J. D., & Krész, M. (2023) · Applied Network Science · doi:10.1007/s41109-022-00527-2 · Cited by 5
Role of microsomal metabolism in bromfenac-induced cytotoxicity
Jeon, J. S., Kim, H., Jo, S., Kim, S. K., & Kim, S. K. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.110903 · Cited by 5
Rutin attenuates ensartinib-induced hepatotoxicity by non-transcriptional regulation of TXNIP
Wu, W., Li, J., Yin, Y., Zhou, Y., Huang, X., Cao, Y., Chen, X., Zhou, Y., Du, J., Xu, Z., et al. (2024) · Cell Biology and Toxicology · doi:10.1007/s10565-024-09883-4 · Cited by 5
Singha, A., Kalladka, K., Harshitha, M., Saha, P., Chakraborty, G., Maiti, B., Akshath, U. S., Chakraborty, A., & Sil, S. K. (2024) · Journal of Microencapsulation · doi:10.1080/02652048.2024.2362188 · Cited by 5
Cyproterone Acetate–Induced Acute Liver Failure: A Case Report and Review of the Literature
Kumar, P., Reddy, S., Kulkarni, A. V., Sharma, M., & Rao, P. N. (2021) · Journal of Clinical and Experimental Hepatology · doi:10.1016/j.jceh.2021.01.003 · Cited by 5
Li, Y., & Zhou, H. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820472-6.00008-6 · Cited by 5
Matrix and Sampling Effects on Quantification of Protein Biomarkers of Drug-Induced Liver Injury
Anselm, V., Sommersdorf, C., Carrasco‐Triguero, M., Katavolos, P., Planatscher, H., Steinhilber, A., Joos, T. O., & Poetz, O. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00478 · Cited by 5
Tang, Z.-M., Yuan, P., Gao, N., Lei, J.-G., Ahmed, M., Hua, Y.-X., Yang, Z.-R., Li, Q.-Y., & Li, H.-Y. (2025) · Molecular Immunology · doi:10.1016/j.molimm.2025.02.008 · Cited by 4
Xu, X., Lü, F., Yu, D., Wang, Y., Chen, P., Hu, W., Jia, S., Wo, J., & Liu, S. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120019 · Cited by 4
Wang, P., Guo, G., Jiang, S., Ding, D., Yang, J., Lü, Y., Han, Y., & Zhou, X. (2025) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2025.102635 · Cited by 4
Molecular mechanisms from the transition of MASLD-MASH-liver fibrosis to liver cancer
Zhang, C., Sui, Y., Liu, S., & Yang, M. J. (2025) · The Journal of Precision Medicine Health and Disease · doi:10.1016/j.premed.2025.100012 · Cited by 4
Metadata
- Authors
- Andrade, R. J., Chalasani, N., Björnsson, E. S., Suzuki, A., Kullak-Ublick, G. A., Watkins, P. B., Devarbhavi, H., Merz, M., Lucena, M. I., Kaplowitz, N., & Aithal, G. P.
- Affiliations
- Indiana University School of Medicine (US)
- Duke University (US)
- Novartis (Switzerland) (CH)
- University of North Carolina at Chapel Hill (US)
- St.John's Medical College Hospital (IN)
- University of Zurich (CH)
- Spanish Clinical Research Network (ES)
- Nottingham University Hospitals NHS Trust (GB)
- Corresponding author
- Lucena, M. Isabel
- ORCID
- Venue
- Nature Reviews Disease Primers
- Published
- 2019-08-22
- Volume
- 5
- Issue
- 1
- Pages
- 58-58
- ISSN
- 2056-676X (ISSN-L)
- OpenAlex
- W1565605888
- Cited by
- 924
- References
- 982
- Citations by year
- 2026: 152 · 2025: 197 · 2024: 161 · 2023: 127 · 2022: 145 · 2021: 97 · 2020: 38
- FWCI
- 9.11
- Type
- journal article
- Language
- en
- Open access
- green
- www.zora.uzh.ch
- Licence
- Locations
- Nature Reviews Disease Primers (publishedVersion)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, other-oa)
- RISalud Institutional Health Repository of Andalucía (submittedVersion, cc-by-nc-nd)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
- Keywords
- drug-induced liver injury, idiosyncratic drug reactions, xenobiotic toxicity, genetic susceptibility, hepatic metabolism, immune response, corticosteroids, immune checkpoint inhibitors, hepatotoxicity
- MeSH terms
- Biopsy, Humans, Risk Factors, Biomarkers, Chemical and Drug Induced Liver Injury
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
