Multifaceted roles of APOE in Alzheimer disease

Cites (279)

Items 201–279 of 279

1. Four Decades of Research in Alzheimer’s Disease (1975–2014): A Bibliometric and Scientometric Analysis
   Alberto Serrano‐Pozo, Georgina M. Aldridge, Qiang Zhang · 2017 · Journal of Alzheimer s Disease
2. Dissociation of Apolipoprotein E Oligomers to Monomer Is Required for High-Affinity Binding to Phospholipid Vesicles
   2011
3. KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
   Neitzel, Julia, Franzmeier, Nicolai, Rubinski, Anna, Dichgans, Martin, Brendel, Matthias, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Weiner, Michael, Aisen, Paul, Petersen, Ronald, Jack, Clifford R. et al. · 2021 · Nature Communications
4. The APOEε3/ε4 Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice
   Kate E. Foley, Amanda A. Hewes, Dylan T. Garceau, Kevin P. Kotredes, Gregory W. Carter, Michael Sasner, Gareth R. Howell · 2022 · Frontiers in Aging Neuroscience
5. APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice
   Area-Gomez, Estela, Larrea, Delfina, Pera, Marta, Agrawal, Rishi R., Guilfoyle, David N., Pirhaji, Leila, Shannon, Kathleen, Arain, Hirra A., Ashok, Archana, Chen, Qiuying et al. · 2020 · Scientific Reports
6. ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants
   Kuo, Chia-Ling, Pilling, Luke C., Atkins, Janice L., Kuchel, George A., Melzer, David · 2020 · Aging
7. O-glycosylation on cerebrospinal fluid and plasma apolipoprotein E differs in the lipid-binding domain
   Flowers, Sarah A, Grant, Oliver C, Woods, Robert J, Rebeck, G William · 2020 · Glycobiology
8. Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes
   Claudia Cicognola, Niklas Mattsson, Danielle van Westen, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Khazar Ahmadi, Olof T. Strandberg, Erik Stomrud, Shorena Janelidze et al. · 2023 · Neurology
9. Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer’s Disease
   Vance, Jeffery M., Farrer, Lindsay A., Huang, Yadong, Cruchaga, Carlos, Hyman, Bradley T., Pericak‐Vance, Margaret A., Goate, Alison M., Greicius, Michael D., Griswold, Anthony J., Haines, Jonathan L. et al. · 2024 · Annals of Neurology
10. Association of African Ancestry–Specific <i>APOE</i> Missense Variant R145C With Risk of Alzheimer Disease
    Le Guen, Yann, Raulin, Ana-Caroline, Logue, Mark W., Sherva, Richard, Belloy, Michael E., Eger, Sarah J., Chen, Annabel, Kennedy, Gabriel, Kuchenbecker, Lindsey, O’Leary, Justin P. et al. · 2023 · JAMA
11. Effect of APOE alleles on the glial transcriptome in normal aging and Alzheimer’s disease
    Serrano-Pozo, Alberto, Li, Zhaozhi, Noori, Ayush, Nguyen, Huong N., Mezlini, Aziz, Li, Liang, Hudry, Eloise, Jackson, Rosemary J., Hyman, Bradley T., Das, Sudeshna · 2021 · Nature Aging
12. Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms
    Stuchell-Brereton, Melissa D., Zimmerman, Maxwell I., Miller, Justin J., Mallimadugula, Upasana L., Incicco, J. Jeremías, Roy, Debjit, Smith, Louis G., Cubuk, Jasmine, Baban, Berevan, DeKoster, Gregory T. et al. · 2023 · Proceedings of the National Academy of Sciences
13. APOE ε4, Alzheimer’s disease pathology, cerebrovascular disease, and cognitive change over the years prior to death.
    Lei Yu, Patricia A. Boyle, Julie A. Schneider, Eisuke Segawa, Robert S. Wilson, Sue E. Leurgans, David Alan Bennett · 2013 · Psychology and Aging
14. Distinct transcriptomic responses to Aβ plaques, neurofibrillary tangles, and <i>APOE</i> in Alzheimer's disease
    Das, Sudeshna, Li, Zhaozhi, Wachter, Astrid, Alla, Srinija, Noori, Ayush, Abdourahman, Aicha, Tamm, Joseph A., Woodbury, Maya E., Talanian, Robert V., Biber, Knut et al. · 2024 · Alzheimer's &amp; Dementia
15. APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation
    Marino, Claudia, Perez‐Corredor, Paula, O'Hare, Michael, Heuer, Annie, Chmielewska, Natalia, Gordon, Harper, Chandrahas, Anita S., Gonzalez‐Buendia, Lucia, Delgado‐Tirado, Santiago, Doan, Tri H. et al. · 2024 · Alzheimer's &amp; Dementia
16. A multi‐hit hypothesis for an <i>APOE4</i> ‐dependent pathophysiological state
    Steele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine et al. · 2022 · European Journal of Neuroscience
17. Clinical, Neuroimaging, and Genetic Markers in Cerebral Amyloid Angiopathy-Related Inflammation: A Systematic Review and Meta-Analysis
    Aikaterini Theodorou, L. Palaiodimou, K. Malhotra, C. Zompola, A. Katsanos, A. Shoamanesh, Estathios Boviatsis, E. Dardiotis, M. Spilioti, S. Sacco et al. · 2022 · Stroke
18. Astrocytic and neuronal apolipoprotein E isoforms differentially affect neuronal excitability
    Konings, Sabine C., Torres-Garcia, Laura, Martinsson, Isak, Gouras, Gunnar K. · 2021 · Frontiers in Neuroscience
19. Plasma NfL is associated with the APOE ε4 allele, brain imaging measurements of neurodegeneration, and lower recall memory scores in cognitively unimpaired late-middle-aged and older adults
    Michael H. Malek‐Ahmadi, Yi Su, Valentina Ghisays, Ji Luo, Vivek Devadas, Yinghua Chen, Wendy Lee, Hillary D. Protas, Kewei Chen, Henrik Zetterberg et al. · 2023 · Alzheimer s Research & Therapy
20. APOEε4 potentiates amyloid β effects on longitudinal tau pathology
    Ferrari-Souza, João Pedro, Bellaver, Bruna, Ferreira, Pâmela C. L., Benedet, Andréa L., Povala, Guilherme, Lussier, Firoza Z., Leffa, Douglas T., Therriault, Joseph, Tissot, Cécile, Soares, Carolina et al. · 2023 · Nature Aging
21. Incomplete dominance of type III hyperlipoproteinemia is associated with the rare apolipoprotein E2 (Arg136 → Ser) variant in multigenerational pedigree studies
    Pocovi, M., Cenarro, A., Civeir, F., Myers, R.H., Casao, E., Esteban, M., Ordovas, J.M. · 1996 · Atherosclerosis
22. Effects of different isoforms of apoE on aggregation of the α‐synuclein protein implicated in Parkinson’s disease
    Emamzadeh, Fatemeh Nouri, Aojula, Harmesh, McHugh, Patrick C., Allsop, David · 2016 · Neuroscience Letters
23. Targeting Apolipoprotein E for Alzheimer’s Disease: An Industry Perspective
    Suidan, Georgette L., Ramaswamy, Gayathri · 2019 · International Journal of Molecular Sciences
24. APOE Antibody Inhibits Aβ‐Associated Tau Seeding and Spreading in a Mouse Model
    Gratuze, Maud, Jiang, Hong, Wang, Chanung, Xiong, Monica, Bao, Xin, Holtzman, David M. · 2022 · Annals of Neurology
25. Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Chao Wang, Maud Gratuze, Fareeha Saadi, Xin Bao, Megan E. Bosch, Choonghee Lee, Hong Jiang, Javier Remolina Serrano, Ernesto R. Gonzales et al. · 2023 · Molecular Neurodegeneration
26. Is ϵ4 the ancestral human apoE allele?
    Robert W. Mahley, Stanley C. Rall · 1999 · Neurobiology of Aging
27. Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects
    Operto, Grégory, Molinuevo, José Luis, Cacciaglia, Raffaele, Falcon, Carles, Brugulat-Serrat, Anna, Suárez-Calvet, Marc, Grau-Rivera, Oriol, Bargalló, Nuria, Morán, Sebastián, Esteller, Manel et al. · 2019 · NeuroImage: Clinical
28. Microglia‐specific <scp>ApoE</scp> knock‐out does not alter Alzheimer's disease plaque pathogenesis or gene expression
    Henningfield, Caden M., Arreola, Miguel A., Soni, Neelakshi, Spangenberg, Elizabeth E., Green, Kim N. · 2022 · Glia
29. The Elusive Nature of APOE ε4 in Mid-adulthood: Understanding the Cognitive Profile
    Claire L. Lancaster, Naji Tabet, Jennifer M. Rusted · 2017 · Journal of the International Neuropsychological Society
30. ApoE mimetic improves pathology and memory in a model of Alzheimer’s disease
    Krishnamurthy, Kamesh, Cantillana, Viviana, Wang, Haichen, Sullivan, Patrick M., Kolls, Bradley J., Ge, Xintong, Lin, Yufeng, Mace, Brian, Laskowitz, Daniel T. · 2020 · Brain Research
31. APOE ε4 carriers may undergo synaptic damage conferring risk of Alzheimer’s disease
    Xiaoyan Sun, C. Dong, B. Levin, Elizabeth A. Crocco, D. Loewenstein, H. Zetterberg, K. Blennow, Clinton B. Wright · 2016 · Alzheimer's & Dementia
32. Apolipoprotein E ε4 disrupts oligodendrocyte differentiation by interfering with astrocyte‐derived lipid transport
    Mok, Kingston King‐Shi, Yeung, Sunny Hoi‐Sang, Cheng, Gerald Wai‐Yeung, Ma, Iris Wai‐Ting, Lee, Ralph Hon‐Sun, Herrup, Karl, Tse, Kai‐Hei · 2023 · Journal of Neurochemistry
33. Dissociable effects of APOE ε4 and β-amyloid pathology on visual working memory
    Kirsty Lu, Jennifer M. Nicholas, Yoni Pertzov, John P Grogan, Masud Husain B, Ivanna M. Pavisic, Sarah‐Naomi James, Thomas D. Parker, Chris Lane, Ashvini Keshavan et al. · 2021 · Nature Aging
34. Apolipoprotein E ε4 Mediates Myelin Breakdown by Targeting Oligodendrocytes in Sporadic Alzheimer Disease
    Cheng, Gerald Wai-Yeung, Mok, Kingston King-Shi, Yeung, Sunny Hoi-Sang, Kofler, Julia, Herrup, Karl, Tse, Kai-Hei · 2022 · Journal of Neuropathology &amp; Experimental Neurology
35. Apolipoprotein- ε 4 is associated with higher fecundity in a natural fertility population
    Benjamin C. Trumble, Mia Charifson, Thomas S. Kraft, Angela R. García, Daniel K. Cummings, Paul L. Hooper, Amanda J. Lea, Daniel Eid Rodríguez, Stephanie V. Koebele, Kenneth H. Buetow et al. · 2023 · Science Advances
36. Genetic resilience to Alzheimer's disease in <i>APOE</i> ε4 homozygotes: A systematic review
    Huq, Aamira J., Fransquet, Peter, Laws, Simon M., Ryan, Joanne, Sebra, Robert, Masters, Colin L., Winship, Ingrid M., James, Paul A., Lacaze, Paul · 2019 · Alzheimer's &amp; Dementia
37. APOE expression and secretion are modulated by mitochondrial dysfunction
    Wynne, Meghan E, Ogunbona, Oluwaseun, Lane, Alicia R, Gokhale, Avanti, Zlatic, Stephanie A, Xu, Chongchong, Wen, Zhexing, Duong, Duc M, Rayaprolu, Sruti, Ivanova, Anna et al. · 2023 · eLife
38. Racial and Ethnic Differences in the Population-Attributable Fractions of Alzheimer Disease and Related Dementias
    Park, Song-Yi, Setiawan, Veronica Wendy, Crimmins, Eileen M., White, Lon R., Wu, Anna H., Cheng, Iona, Darst, Burcu F., Haiman, Christopher A., Wilkens, Lynne R., Le Marchand, Loїc et al. · 2024 · Neurology
39. Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer
    Petros, Andrew M., Korepanova, Alla, Jakob, Clarissa G., Qiu, Wei, Panchal, Sanjay C., Wang, Jie, Dietrich, Justin D., Brewer, Jason T., Pohlki, Frauke, Kling, Andreas et al. · 2019 · Journal of Medicinal Chemistry
40. Opposing Roles of apolipoprotein E in aging and neurodegeneration
    Hudry, Eloise, Klickstein, Jacob, Cannavo, Claudia, Jackson, Rosemary, Muzikansky, Alona, Gandhi, Sheetal, Urick, David, Sargent, Taylie, Wrobleski, Lauren, Roe, Allyson D et al. · 2019 · Life Science Alliance
41. Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate
    Nemergut, Michal, Marques, Sérgio M., Uhrik, Lukas, Vanova, Tereza, Nezvedova, Marketa, Gadara, Darshak Chandulal, Jha, Durga, Tulis, Jan, Novakova, Veronika, Planas-Iglesias, Joan et al. · 2023 · Molecular Neurodegeneration
42. Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer’s disease
    Langella, Stephanie, Barksdale, N. Gil, Vasquez, Daniel, Aguillon, David, Chen, Yinghua, Su, Yi, Acosta-Baena, Natalia, Acosta-Uribe, Juliana, Baena, Ana Y., Garcia-Ospina, Gloria et al. · 2023 · Nature Communications
43. Haplotype analysis of the apolipoprotein E and apolipoprotein C1 loci in Portugal and São Tomé e Príncipe (Gulf of Guinea): linkage disequilibrium evidence that APOE*4 is the ancestral APOE allele.
    Susana Seixas, Maria Jesus Trovoada, Jorge Rocha · 1999 · PubMed
44. Assessment of APOE in atypical parkinsonism syndromes
    Sabir, Marya S., Blauwendraat, Cornelis, Ahmed, Sarah, Serrano, Geidy E., Beach, Thomas G., Perkins, Matthew, Rice, Ann C., Masliah, Eliezer, Morris, Christopher M., Pihlstrom, Lasse et al. · 2019 · Neurobiology of Disease
45. Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins
    Strickland, Michael R., Rau, Michael J., Summers, Brock, Basore, Katherine, Wulf, John, Jiang, Hong, Chen, Yun, Ulrich, Jason D., Randolph, Gwendalyn J., Zhang, Rui et al. · 2024 · Neuron
46. <i>APOE</i> genotypes as a risk factor for age‐dependent accumulation of cerebrovascular disease in older adults
    Lamar, Melissa, Yu, Lei, Rubin, Leah H., James, Bryan D., Barnes, Lisa L., Farfel, Jose Marcelo, Gaiteri, Chris, Buchman, Aron S., Bennett, David A., Schneider, Julie A. · 2019 · Alzheimer's &amp; Dementia
47. Short-term memory advantage for brief durations in human APOE ε4 carriers
    Nahid Zokaei, John P Grogan, Sean James Fallon, Ellie Slavkova, Jonathan Hadida, Sanjay Manohar, Anna Christina Nobre, Masud Husain B · 2020 · Scientific Reports
48. Cognitive resistance to and resilience against multiple comorbid neurodegenerative pathologies and the impact of <i>APOE</i> status
    Walker, Jamie M, Richardson, Timothy E · 2023 · Journal of Neuropathology &amp; Experimental Neurology
49. Multiple system atrophy and apolipoprotein E
    Ogaki, Kotaro, Martens, Yuka A., Heckman, Michael G., Koga, Shunsuke, Labbé, Catherine, Lorenzo‐Betancor, Oswaldo, Wernick, Anna I., Walton, Ronald L., Soto, Alexandra I., Vargas, Emily R. et al. · 2018 · Movement Disorders
50. Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay
    Kara, Eleanna, Marks, Jordan D., Fan, Zhanyun, Klickstein, Jacob A., Roe, Allyson D., Krogh, Kelly A., Wegmann, Susanne, Maesako, Masato, Luo, Christina C., Mylvaganam, Ravi et al. · 2017 · Journal of Biological Chemistry
51. Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk
    Muhammad Ali, Yun Ju Sung, Fengxian Wang, María Victoria Fernández, John C. Morris, Anne M. Fagan, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per Johansson et al. · 2022 · PLoS ONE
52. Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets
    Karen Nuytemans, Marina Lipkin Vasquez, Liyong Wang, Derek Van Booven, Antony J. Griswold, Farid Rajabli, Katrina Celis, Oded Oron, Natalia K. Hofmann, Sophie Rolati et al. · 2022 · Alzheimer s & Dementia
53. Differential associations between apolipoprotein E alleles and cerebral myelin content in normative aging
    Curtis Triebswetter, Matthew Kiely, Nikkita Khattar, Luigi Ferrucci, Susan M. Resnick, Richard G. S. Spencer, Mustapha Bouhrara · 2022 · NeuroImage
54. Apolipoprotein ɛ4-Associated Protection Against Pediatric Enteric Infections Is a Survival Advantage in Pre-Industrial Populations
    Carr J. Smith, John Wesson Ashford · 2023 · Journal of Alzheimer s Disease
55. Cognitively Normal APOE ε4 Carriers Have Specific Elevation of CSF SNAP-25
    Omar Hameed Butt, Justin M. Long, Rachel L. Henson, Elizabeth M. Herries, Courtney L. Sutphen, Anne M. Fagan, Carlos Cruchaga, Jack H. Ladenson, David M. Holtzman, John C. Morris et al. · 2020 · Neurobiology of Aging
56. The protective gene dose effect of the APOEε2 allele on gray matter volume in cognitively unimpaired individuals
    Gemma Salvadó, Daniel Ferreira, Grégory Operto, Irene Cumplido‐Mayoral, Eider M. Arenaza‐Urquijo, Raffaele Cacciaglia, Carles Falcón, Natàlia Vilor‐Tejedor, Carolina Minguillón, Colin Groot et al. · 2021 · Alzheimer s & Dementia
57. Astrocytic function is associated with both amyloid-β and tau pathology in non-demented APOE ϵ4 carriers
    Nicola Spotorno, Chloé Najac, Erik Stomrud, Niklas Mattsson, Sebastian Palmqvist, Danielle van Westen, Itamar Ronen, Oskar Hansson · 2022 · Brain Communications
58. A flow cytometry–based in vitro assay reveals that formation of apolipoprotein E (ApoE)–amyloid beta complexes depends on ApoE isoform and cell type
    Kara, Eleanna, Marks, Jordan D., Roe, Allyson D., Commins, Caitlin, Fan, Zhanyun, Calvo-Rodriguez, Maria, Wegmann, Susanne, Hudry, Eloise, Hyman, Bradley T. · 2018 · Journal of Biological Chemistry
59. Apolipoprotein E Facilitates Amyloid-β Oligomer-Induced Tau Phosphorylation
    Hou, Ting-ting, Han, Yun-Dan, Cong, Lin, Liu, Cui-cui, Liang, Xiao-Yan, Xue, Fu-zhong, Du, Yi-feng · 2020 · Journal of Alzheimer’s Disease
60. Heterozygous <i>APOE</i> Christchurch in familial Alzheimer’s disease without mutations in other Mendelian genes
    Hernandez, Isabel, Gelpi, Ellen, Molina‐Porcel, Laura, Bernal, Sara, Rodríguez‐Santiago, Benjamín, Dols‐Icardo, Oriol, Ruiz, Agustín, Alcolea, Daniel, Boada, Mercè, Lleó, Alberto et al. · 2021 · Neuropathology and Applied Neurobiology
61. Associations of APOE e2 genotype with cerebrovascular pathology: a postmortem study of 1275 brains
    Goldberg, Terry E, Huey, Edward D, Devanand, Davangere P · 2021 · Journal of Neurology, Neurosurgery &amp; Psychiatry
62. Risk of dementia in <i>APOE</i> ε4 carriers is mitigated by a polygenic risk score
    Ebenau, Jarith L., van der Lee, Sven J., Hulsman, Marc, Tesi, Niccolò, Jansen, Iris E., Verberk, Inge M.W., van Leeuwenstijn, Mardou, Teunissen, Charlotte E., Barkhof, Frederik, Prins, Niels D. et al. · 2021 · Alzheimer's &amp; Dementia: Diagnosis, Assessment &amp; Disease Monitoring
63. Apolipoprotein ε4 is associated with better cognitive control allocation in healthy young adults
    Nicolas Zink, Wiebke Bensmann, Larissa Arning, Christian Beste, Ann‐Kathrin Stock · 2018 · NeuroImage
64. AD and non‐AD mediators of the pathway between the APOE genotype and cognition
    Emma L. Nichols, Adam M. Brickman, Kaitlin Blackstone Casaletto, Kristen Dams-O’Connor, Kristen M. George, Raj G. Kumar, Priya Palta, Jennifer S. Rabin, Claudia Liliana Satizábal, Julie A. Schneider et al. · 2022 · Alzheimer s & Dementia
65. APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology
    Seth D. Talyansky, Yann Le Guen, Nandita M. Kasireddy, Michaël E. Belloy, Michael D. Greicius · 2023 · Acta Neuropathologica Communications
66. Neuropathology-Independent Association Between APOE Genotype and Cognitive Decline Rate in the Normal Aging-Early Alzheimer Continuum
    Jing Qian, Yiding Zhang, Rebecca A. Betensky, Bradley T. Hyman, Alberto Serrano‐Pozo · 2023 · Neurology Genetics
67. Update on modifiable risk factors for Alzheimer’s disease and related dementias
    Methasit Jaisa-aad, C. Muñoz-Castro, A. Serrano-Pozo · 2024 · Current Opinion in Neurology
68. Polygenic score modifies risk for Alzheimer's disease in <i>APOE</i> ε4 homozygotes at phenotypic extremes
    Huq, Aamira J., Fulton‐Howard, Brian, Riaz, Moeen, Laws, Simon, Sebra, Robert, Ryan, Joanne, Alzheimer's Disease Genetics Consortium, Renton, Alan E., Goate, Alison M., Masters, Colin L. et al. · 2021 · Alzheimer's &amp; Dementia: Diagnosis, Assessment &amp; Disease Monitoring
69. Putting attention in the spotlight: The influence of APOE genotype on visual search in mid adulthood
    Claire Lancaster, S. Forster, N. Tabet, J. Rusted · 2017 · Behavioural Brain Research
70. Modifying effects of race and ethnicity and <i>APOE</i> on the association of physical activity with risk of Alzheimer's disease and related dementias
    Park, Song‐Yi, Setiawan, Veronica Wendy, White, Lon R., Wu, Anna H., Cheng, Iona, Haiman, Christopher A., Wilkens, Lynne R., Le Marchand, Loїc, Lim, Unhee · 2023 · Alzheimer's &amp; Dementia
71. The APOE paradox: do attentional control differences in mid-adulthood reflect risk of late-life cognitive decline
    Claire L. Lancaster, Naji Tabet, Jennifer M. Rusted · 2016 · Neurobiology of Aging
72. Interactions between the apolipoprotein E4 gene and modifiable risk factors for cognitive impairment: a nationally representative panel study
    Kolli, Ajay, Zhou, Yunshu, Chung, Grace, Ware, Erin B., Langa, Kenneth M., Ehrlich, Joshua R. · 2022 · BMC Geriatrics
73. <scp>APOE2</scp> Exacerbates <scp>TDP</scp>‐43 Related Toxicity in the Absence of Alzheimer Pathology
    Meneses, Axel D., Koga, Shunsuke, Li, Zonghua, O'Leary, Justin, Li, Fuyao, Chen, Kai, Murakami, Aya, Qiao, Wenhui, Kurti, Aishe, Heckman, Michael G. et al. · 2023 · Annals of Neurology
74. Carboxyl truncation of α-synuclein occurs early and is influenced by human APOE genotype in transgenic mouse models of α-synuclein pathogenesis
    Lloyd, Grace M., Long, Brooke, Quintin, Stephan, Sorrentino, Zachary A., Gorion, Kimberly-Marie M., Bell, Brach M., Carrillo, Denise, Sullivan, Patrick, Borchelt, David, Giasson, Benoit I. · 2023 · Acta Neuropathologica Communications
75. Role of apolipoprotein E in β-amyloidogenesis: Isoform-specific effects on protofibril to fibril conversion of Aβ in vitro and brain Aβ deposition in vivo.
    Hori, Yukiko, Hashimoto, Tadafumi, Nomoto, Hidetoshi, Hyman, Bradley T., Iwatsubo, Takeshi · 2018 · Journal of Biological Chemistry
76. Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants
    He, Karen Y., Khramtsova, Ekaterina A., Cabrera-Socorro, Alfredo, Zhang, Yanfei, Li, Shuwei, Sarver, Brice A. J., Smets, Bart, Li, Qingqin S., De Muynck, Louis, Parrado, Antonio R. et al. · 2023 · Molecular Neurodegeneration
77. APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice
    Bonnar, Orla, Shaw, Kira, Anderle, Silvia, Grijseels, Dori M, Clarke, Devin, Bell, Laura, King, Sarah L, Hall, Catherine N · 2023 · Journal of Cerebral Blood Flow &amp; Metabolism
78. Patients asking about APOE gene test results? Here’s what to tell them
    Stites · 2022 · The Journal of Family Practice
79. APOE Allele Switching in a Novel Transgenic Mouse Model as a Therapeutic Approach for Alzheimer’s Disease
    Lesley R. Golden, Lance A. Johnson · 2022 · Alzheimer s & Dementia