CaMKII: a central molecular organizer of synaptic plasticity, learning and memory

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

Traynelis, S. F., Wollmuth, L. P., McBain, C. J., Menniti, F. S., Vance, K. M., Ogden, K. K., Hansen, K. B., Yuan, H., Myers, S. J., & Dingledine, R. (2010) · Pharmacological Reviews · doi:10.1124/pr.109.002451 · Cited by 3,568 · see citing works

Structural basis of long-term potentiation in single dendritic spines

Matsuzaki, M., Honkura, N., Ellis-Davies, G. C. R., & Kasai, H. (2004) · Nature · doi:10.1038/nature02617 · Cited by 2,500 · see citing works

The molecular basis of CaMKII function in synaptic and behavioural memory

Lisman, J., Schulman, H., & Cline, H. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn753 · Cited by 1,860 · see citing works

Mechanisms of CaMKII action in long-term potentiation

Lisman, J., Yasuda, R., & Raghavachari, S. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3192 · Cited by 1,134 · see citing works

The Postsynaptic Architecture of Excitatory Synapses: A More Quantitative View

Sheng, M., & Hoogenraad, C. C. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.060805.160029 · Cited by 1,003 · see citing works

Interaction with the NMDA receptor locks CaMKII in an active conformation

Bayer, K.-U., De Koninck, P., Leonard, A. S., Hell, J. W., & Schulman, H. (2001) · Nature · doi:10.1038/35081080 · Cited by 732 · see citing works

Structural and Molecular Remodeling of Dendritic Spine Substructures during Long-Term Potentiation

Bosch, M., Castro, J., Saneyoshi, T., Matsuno, H., Sur, M., & Hayashi, Y. (2014) · Neuron · doi:10.1016/j.neuron.2014.03.021 · Cited by 637 · see citing works

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

Murakoshi, H., Wang, H., & Yasuda, R. (2011) · Nature · doi:10.1038/nature09823 · Cited by 564 · see citing works

Impermanence of dendritic spines in live adult CA1 hippocampus

Attardo, A., Fitzgerald, J. E., & Schnitzer, M. J. (2015) · Nature · doi:10.1038/nature14467 · Cited by 399 · see citing works

Kalirin-7 Controls Activity-Dependent Structural and Functional Plasticity of Dendritic Spines

Xie, Z., Srivastava, D. P., Photowala, H., Kai, L., Cahill, M. E., Woolfrey, K. M., Shum, C. Y., Surmeier, D. J., & Penzes, P. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.005 · Cited by 373 · see citing works

Structure of the Autoinhibited Kinase Domain of CaMKII and SAXS Analysis of the Holoenzyme

Rosenberg, O. S., Deindl, S., Sung, R.-J., Nairn, A. C., & Kuriyan, J. (2005) · Cell · doi:10.1016/j.cell.2005.10.029 · Cited by 333 · see citing works

Potentiated transmission and prevention of further LTP by increased CaMKII activity in postsynaptic hippocampal slice neurons

Pettit, D. L., Perlman, S., & Malinow, R. (1994) · Science · doi:10.1126/science.7997883 · Cited by 329 · see citing works

The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure

Okamoto, K.-I., Narayanan, R., Lee, S. H., Murata, K., & Hayashi, Y. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701656104 · Cited by 328 · see citing works

Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP

Araki, Y., Zeng, M., Zhang, M., & Huganir, R. L. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.023 · Cited by 271 · see citing works

Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines

Bingol, B., Wang, C.-F., Arnott, D., Cheng, D., Peng, J., & Sheng, M. (2010) · Cell · doi:10.1016/j.cell.2010.01.024 · Cited by 268 · see citing works

Specific Roles of AMPA Receptor Subunit GluR1 (GluA1) Phosphorylation Sites in Regulating Synaptic Plasticity in the CA1 Region of Hippocampus

Lee, H.-K., Takamiya, K., He, K., Song, L., & Huganir, R. L. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00835.2009 · Cited by 261 · see citing works

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability

Küry, S., van Woerden, G. M., Besnard, T., Proietti Onori, M., Latypova, X., Towne, M. C., Cho, M. T., Prescott, T. E., Ploeg, M. A., Sanders, S., et al. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.10.003 · Cited by 185 · see citing works

Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

Woolfrey, K. M., Srivastava, D. P., Photowala, H., Yamashita, M., Barbolina, M. V., Cahill, M. E., Xie, Z., Jones, K. A., Quilliam, L. A., Prakriya, M., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2386 · Cited by 161 · see citing works

CaMKII Autophosphorylation Is Necessary for Optimal Integration of Ca 2+ Signals during LTP Induction, but Not Maintenance

Chang, J.-Y., Parra-Bueno, P., Laviv, T., Szatmari, E. M., Lee, S.-J. R., & Yasuda, R. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.041 · Cited by 161 · see citing works

CaMKII "Autonomy" Is Required for Initiating But Not for Maintaining Neuronal Long-Term Information Storage

Buard, I., Coultrap, S. J., Freund, R. K., Lee, Y.-S., Dell'Acqua, M. L., Silva, A. J., & Bayer, K. U. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1469-10.2010 · Cited by 160 · see citing works

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation

Hosokawa, T., Liu, P.-W., Cai, Q., Ferreira, J. S., Levet, F., Butler, C., Sibarita, J.-B., Choquet, D., Groc, L., Hosy, E., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00843-3 · Cited by 146 · see citing works

Kinase-Dead Knock-In Mouse Reveals an Essential Role of Kinase Activity of Ca2+/Calmodulin-Dependent Protein Kinase II  in Dendritic Spine Enlargement, Long-Term Potentiation, and Learning

Yamagata, Y., Kobayashi, S., Umeda, T., Inoue, A., Sakagami, H., Fukaya, M., Watanabe, M., Hatanaka, N., Totsuka, M., Yagi, T., et al. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0707-09.2009 · Cited by 146 · see citing works

A Temporary Gating of Actin Remodeling during Synaptic Plasticity Consists of the Interplay between the Kinase and Structural Functions of CaMKII

Kim, K., Lakhanpal, G., Lu, H. E., Khan, M., Suzuki, A., Kato Hayashi, M., Narayanan, R., Luyben, T. T., Matsuda, T., Nagai, T., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.023 · Cited by 145 · see citing works

Is Persistent Activity of Calcium/Calmodulin-Dependent Kinase Required for the Maintenance of LTP?

Chen, H.-X., Otmakhov, N., Strack, S., Colbran, R. J., & Lisman, J. E. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.4.1368 · Cited by 126 · see citing works

Reciprocal Activation within a Kinase-Effector Complex Underlying Persistence of Structural LTP

Saneyoshi, T., Matsuno, H., Suzuki, A., Murakoshi, H., Hedrick, N. G., Agnello, E., O’Connell, R., Stratton, M. M., Yasuda, R., & Hayashi, Y. (2019) · Neuron · doi:10.1016/j.neuron.2019.04.012 · Cited by 119 · see citing works

Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation

Chao, L. H., Pellicena, P., Deindl, S., Barclay, L. A., Schulman, H., & Kuriyan, J. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1751 · Cited by 119 · see citing works

CaMKIIβ binding to stable F-actin <i>in vivo</i> regulates F-actin filament stability

Lin, Y.-C., & Redmond, L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804399105 · Cited by 96 · see citing works

DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific

Goodell, D. J., Zaegel, V., Coultrap, S. J., Hell, J. W., & Bayer, K. U. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.05.068 · Cited by 88 · see citing works

LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes

Sheng, N., Bemben, M. A., Díaz-Alonso, J., Tao, W., Shi, Y. S., & Nicoll, R. A. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800719115 · Cited by 65 · see citing works

Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin‐dependent protein kinase II

Ishida, A., Shigeri, Y., Tatsu, Y., Uegaki, K., Kameshita, I., Okuno, S., Kitani, T., Yumoto, N., & Fujisawa, H. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00405-0 · Cited by 64 · see citing works

Neuronal L-Type Calcium Channel Signaling to the Nucleus Requires a Novel CaMKIIα-Shank3 Interaction

Perfitt, T. L., Wang, X., Dickerson, M. T., Stephenson, J. R., Nakagawa, T., Jacobson, D. A., & Colbran, R. J. (2020) · The Journal of Neuroscience · doi:10.1523/jneurosci.0893-19.2020 · Cited by 54 · see citing works

Subcellular organization of camkii in rat hippocampal pyramidal neurons

Ding, J., Kennedy, M. B., & Weinberg, R. J. (2013) · Journal of Comparative Neurology · doi:10.1002/cne.23372 · Cited by 45 · see citing works

Activity-dependent redistribution of CaMKII in the postsynaptic compartment of hippocampal neurons

Tao-Cheng, J.-H. (2020) · Molecular Brain · doi:10.1186/s13041-020-00594-5 · Cited by 38 · see citing works

Synaptic memory and CaMKII

Nicoll, R. A., & Schulman, H. (2023) · Physiological Reviews · doi:10.1152/physrev.00034.2022 · Cited by 126 · see citing works

LTP expression mediated by autonomous activity of GluN2B-bound CaMKII

Rumian, N. L., Barker, C. M., Larsen, M. E., Tullis, J. E., Freund, R. K., Taslimi, A., Coultrap, S. J., Tucker, C. L., Dell’Acqua, M. L., & Bayer, K. U. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114866 · Cited by 20 · see citing works

Multimodal synaptomics reveals coordinated synaptic activity, protein synthesis and reorganization in NMDAR regulation

Falkovich, R., Aryal, S., Sheng, M., & Bathe, M. (2024) · doi:10.1101/2024.10.28.620504 · Cited by 2 · see citing works