Cited by 2,098SARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studiesvaccines and immunoinformatics approaches

The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.

SARS-CoV-2 vaccines in development

Open access
Krammer, Florian·2020·Nature

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late 2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. To mitigate the effects of the virus on public health, the economy and society, a vaccine is urgently needed. Here I review the development of vaccines against SARS-CoV-2. Development was initiated when the genetic sequence of the virus became available in early January 2020, and has moved at an unprecedented speed: a phase I trial started in March 2020 and there are currently more than 180 vaccines at various stages of development. Data from phase I and phase II trials are already available for several vaccine candidates, and many have moved into phase III trials. The data available so far suggest that effective and safe vaccines might become available within months, rather than years.

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Crossref · 10.1038/s41586-020-2798-3

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Citations

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Research works printed but not linked: 1

  1. The National Academies of Sciences, Engineering and Medicine. Discussion Draft of the Preliminary Framework for Equitable Allocation of COVID-19 Vaccine (The National Academies Press, 2020).

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Metadata

Authors
Krammer, F.
Affiliations
Icahn School of Medicine at Mount Sinai (US)
Corresponding author
Krammer, Florian
Venue
Nature
Published
2020-09-23
Volume
586
Issue
7830
Pages
516-527
ISSN
  • 0028-0836 (ISSN-L)
  • 1476-4687
OpenAlex
W3087924281
Cited by
2,098
References
101
Citations by year
2026: 91 · 2025: 147 · 2024: 173 · 2023: 287 · 2022: 538 · 2021: 747 · 2020: 112
FWCI
19.97
Type
journal article
Language
en
Open access
Locations
  • Nature (publishedVersion)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (cc-by)
Funders
  • JPB Foundation (2020-215611, HHSN272201400008C, 75N93019C00051)
  • Open Philanthropy Project (#2020-215611, 75N93019C00051, HHSN272201400008C)
  • National Institute of Allergy and Infectious Diseases (HHSN272201400008C), 75N93019C00051, 2020-215611, HHSN272201800048C)
Topics
  • Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Virus Infections Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
Keywords
SARS-CoV-2, COVID-19 vaccines, vaccine development, vaccine candidate, clinical trials, animal studies, vaccine safety, vaccine efficacy, COVID-19 pandemic
MeSH terms
Drug Development, COVID-19, COVID-19 Vaccines, Animals, Clinical Trials as Topic, Drug Industry, Humans, Pneumonia, Viral, Viral Vaccines, Coronavirus Infections, Immunity, Mucosal, Pandemics

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