Cited by 185Protein Structure and DynamicsArtificial Intelligence in Healthcare and EducationComputational Drug Discovery Methods

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AlphaFold heralds a data-driven revolution in biology and medicine

Thornton, Janet M., Laskowski, Roman A., Borkakoti, Neera·2021·Nature Medicine

DOI 10.1038/s41591-021-01533-0

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PDBsum: Structural summaries of PDB entries
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Protein Data Bank: the single global archive for 3D macromolecular structure data
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Authors: Thornton, J. M., Laskowski, R. A., & Borkakoti, N.
Affiliations: European Bioinformatics Institute (GB)
Corresponding author: Thornton, Janet M.
ORCID: Thornton, Janet M.
Laskowski, Roman A.
Borkakoti, Neera
Venue: Nature Medicine
Publisher: Springer Science and Business Media LLC
Published: 2021-10
Volume: 27
Issue: 10
Pages: 1666-1669
ISSN: 1078-8956 (ISSN-L)
1546-170X
DOI: 10.1038/s41591-021-01533-0
OpenAlex: W3207457994
Cited by: 185
References: 17
Citations by year: 2026: 14 · 2025: 22 · 2024: 41 · 2023: 57 · 2022: 46 · 2021: 5
FWCI: 11.69
Type: journal article
Language: en
Open access: closed
Licence: www.springernature.com/gp/researchers/text-and-data-mining (tdm)
www.springernature.com/gp/researchers/text-and-data-mining (vor)
Locations: Nature Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Computational Drug Discovery Methods
Keywords: AlphaFold, protein structure prediction, artificial intelligence in biology, clinical data, human disease, data-driven medicine
MeSH terms: Artificial Intelligence, Humans, Protein Conformation, Proteins, Software, Biomedical Research

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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AlphaFold heralds a data-driven revolution in biology and medicine

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