The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Allogeneic BCMA-targeting CAR T cells in relapsed/refractory multiple myeloma: phase 1 UNIVERSAL trial interim results
Abstract
ALLO-715 is a first-in-class, allogeneic, anti-BCMA CAR T cell therapy engineered to abrogate graft-versus-host disease and minimize CAR T rejection. We evaluated escalating doses of ALLO-715 after lymphodepletion with an anti-CD52 antibody (ALLO-647)-containing regimen in 43 patients with relapsed/refractory multiple myeloma as part A of the ongoing first-in-human phase 1 UNIVERSAL trial. Primary objectives included determination of the safety and tolerability of ALLO-715 and the safety profile of the ALLO-647-containing lymphodepletion regimen. Key secondary endpoints were response rate and duration of response. Grade ≥3 adverse events were reported in 38 (88.0%) of patients. Cytokine release syndrome was observed in 24 patients (55.8%), with 1 grade ≥3 event (2.3%) and neurotoxicity in 6 patients (14%), with no grade ≥3 events. Infections occurred in 23 patients (53.5%), with 10 (23.3%) of grade ≥3. Overall, 24 patients (55.8%) had a response. Among patients treated with 320 × 10 6 CAR+ T cells and a fludarabine-, cyclophosphamide- and ALLO-647-based lymphodepletion regimen (n = 24), 17 (70.8%) had a response including 11 (45.8%) with very good partial response or better and 6 (25%) with a complete response/stringent complete response. The median duration of response was 8.3 months. These initial results support the feasibility and safety of allogeneic CAR T cell therapy for myeloma.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The ORR was 70.8%, with VGPR in 45.8% of patients and the CR or sCR in 25% of patients.”
From Multiple myeloma: signaling pathways and targeted therapy (2024) · cites this paper as [252]
In the citing paper
“Adverse events included CRS in 55.8% of patients, neurotoxicity in 14% of patients, and infections in 53.5% of patients.”
From Multiple myeloma: signaling pathways and targeted therapy (2024) · cites this paper as [252]
In the citing paper
“The median DOR was 8.3 months.”
From Multiple myeloma: signaling pathways and targeted therapy (2024) · cites this paper as [252]
Citations
Cites
Lee, D. W., Santomasso, B. D., Locke, F. L., Ghobadi, A., Turtle, C. J., Brudno, J. N., Maus, M. V., Park, J. H., Mead, E., Pavletic, S., et al. (2019) · Biology of Blood and Marrow Transplantation · doi:10.1016/j.bbmt.2018.12.758 · Cited by 3,675
Kumar, S., Paiva, B., Anderson, K. C., Durie, B., Landgren, O., Moreau, P., Munshi, N., Lonial, S., Bladé, J., Mateos, M.-V., et al. (2016) · The Lancet Oncology · doi:10.1016/s1470-2045(16)30206-6 · Cited by 3,061
Self-citationIdecabtagene Vicleucel in Relapsed and Refractory Multiple Myeloma.
Munshi, N. C., Anderson, L. D., Shah, N., Madduri, D., Berdeja, J., Lonial, S., Raje, N., Lin, Y., Siegel, D., Oriol, A., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2024850 · Cited by 2,560
Berdeja, J. G., Madduri, D., Usmani, S. Z., Jakubowiak, A., Agha, M., Cohen, A. D., Stewart, A. K., Hari, P., Htut, M., Lesokhin, A., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00933-8 · Cited by 1,756
Self-citationEngineering strategies to overcome the current roadblocks in CAR T cell therapy
Rafiq, S., Hackett, C. S., & Brentjens, R. J. (2019) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-019-0297-y · Cited by 1,525
Teclistamab in Relapsed or Refractory Multiple Myeloma
Moreau, P., Garfall, A. L., van de Donk, N. W. C. J., Nahi, H., San-Miguel, J. F., Oriol, A., Nooka, A. K., Martin, T., Rosinol, L., Chari, A., et al. (2022) · New England Journal of Medicine · doi:10.1056/nejmoa2203478 · Cited by 1,269
Self-citationLonial, S., Lee, H. C., Badros, A., Trudel, S., Nooka, A. K., Chari, A., Abdallah, A.-O., Callander, N., Lendvai, N., Sborov, D., et al. (2020) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30788-0 · Cited by 812
Kumar, S. K., Lee, J. H., Lahuerta, J. J., Morgan, G., Richardson, P. G., Crowley, J., Haessler, J., Feather, J., Hoering, A., Moreau, P., et al. (2012) · Leukemia · doi:10.1038/leu.2011.196 · Cited by 721
Self-citationB-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma
Carpenter, R. O., Evbuomwan, M. O., Pittaluga, S., Rose, J. J., Raffeld, M. A., Yang, S., Gress, R. E., Hakim, F. T., & Kochenderfer, J. N. (2013) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-12-2422 · Cited by 667
Martin, T., Usmani, S. Z., Berdeja, J. G., Agha, M., Cohen, A. D., Hari, P., Avigan, D., Deol, A., Htut, M., Lesokhin, A., et al. (2023) · Journal of Clinical Oncology · doi:10.1200/jco.22.00842 · Cited by 663
Self-citation
Research works printed but not linked: 1
- Prevention and Treatment of Cancer-Related Infections (Version 3.2022). NCCN Clinical Practice Guidelines in Oncology, Vol. 2022 (National Comprehensive Cancer Network, 2022).
Cited by
Sorted by citations
Items 101–200 of 256
Targeting B Cell Maturation Antigen in Patients with Multiple Myeloma: Current Perspectives
Shrivastava, T., van Rhee, F., & Hadidi, S. A. (2023) · OncoTargets and Therapy · doi:10.2147/ott.s370880 · Cited by 13
Besliu, C., Tănase, A., Rotaru, I., Espinoza, J., Vidal, L., Poelman, M., Juan, M., de Larrea, C. F., & Saini, K. S. (2025) · Cancers · doi:10.3390/cancers17030525 · Cited by 15
Cheema, A. Y., Ali, H. M., Bibi, M., Aslam, M. F., Thiagarajan, P. S., Shahid, D., Munir, M., Najam, A., Raza, S., & Anwer, F. (2025) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2025.09.044 · Cited by 14
Self-citationPreclinical activity of allogeneic SLAMF7-specific CAR T-cells (UCARTCS1) in multiple myeloma
Korst, C. L. B. M., O’Neill, C. A., Bruins, W. S. C., Cosovic, M., Twickler, I., Verkleij, C. P. M., Clerre, D. L., Themeli, M., Chion-Sotinel, I., Zweegman, S., et al. (2024) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2023-008769 · Cited by 13
Chen, J., Zhao, L., Li, W., Wang, S., Li, J., Lv, Z., Zhao, Y., Liang, J., Hu, Z., Pan, F., et al. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-06853-0 · Cited by 12
Off-the-shelf CAR T cells for multiple myeloma
Brudno, J. N., & Kochenderfer, J. N. (2023) · Nature Medicine · doi:10.1038/s41591-022-02195-2 · Cited by 12
BCMA CAR-T cells in multiple myeloma–ready for take-off?
Scheller, L., Tebuka, E., Rambau, P., Einsele, H., Hudecek, M., Prommersberger, S., & Danhof, S. (2023) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.1080/10428194.2023.2276676 · Cited by 14
Mechanisms of Resistance to CAR T-Cells and How to Overcome Them
Legato, L., Bisio, M., Fasano, F., Savelli, C. B., Secreto, C., Dellacasa, C. M., Botto, B., Busca, A., Cerrano, M., Freilone, R., et al. (2025) · Methods and Protocols · doi:10.3390/mps8050108 · Cited by 14
Therapeutic targeting of the protein tyrosine kinase-7 in cancer: an overview
Mottard, K., Cokaiko, J., Rogister, B., & Neirinckx, V. (2024) · The Oncologist · doi:10.1093/oncolo/oyae290 · Cited by 11
CAR T cell therapy in multiple myeloma, where are we now and where are we heading for?
Fischer, L., Grieb, N., Platzbecker, U., Vučinić, V., & Merz, M. (2023) · European Journal of Haematology · doi:10.1111/ejh.14051 · Cited by 11
Harnessing the potential of gene editing technology for CAR-T cell therapy of solid tumors
Khodabandehloo, E., Rayati, M., Ahmadi, E., Naghdibadi, M., Moradi, V., & Ahmadbeigi, N. (2025) · Inflammation and Regeneration · doi:10.1186/s41232-025-00398-x · Cited by 13
Liu, Z., Liu, X., Ma, J., Zhang, Y., Ye, M., Liu, H., Ding, K., Song, J., Fu, R., & Qi, J. (2025) · Advanced Materials · doi:10.1002/adma.202518663 · Cited by 10
Allogeneic CAR-T cells for cancer immunotherapy
Chen, X., Gao, Y., & Zhang, Y. (2024) · Immunotherapy · doi:10.1080/1750743x.2024.2408048 · Cited by 10
Caël, B., Bôle‐Richard, E., Garnache‐Ottou, F., & Aubin, F. (2024) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2024.12.1066 · Cited by 13
Pereira, R., & Bergantim, R. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25094996 · Cited by 10
Martino, M., Gamberi, B., Antonioli, E., Aquino, S., Pepa, R. D., Malerba, L., Mangiacavalli, S., Pezzatti, S., Bringhen, S., & Zamagni, E. (2024) · Expert Review of Hematology · doi:10.1080/17474086.2024.2357274 · Cited by 10
Hamadeh, I., Friend, R., Mailankody, S., & Atrash, S. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1455464 · Cited by 9
Self-citationCAR T-cell therapy to treat multiple myeloma: current state and future directions
Reddy, S. T., Hosoya, H., & Mikkilineni, L. (2024) · Cancer and Metastasis Reviews · doi:10.1007/s10555-024-10219-1 · Cited by 10
Overcoming cancer immunotherapy barriers via nanomaterial-mediated pyroptosis
Xie, J., Peng, B., Xiao, Y., Chen, X., Zhang, X., Chen, D., Song, L., Xu, M., Liao, W., & Zhang, X. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01024a · Cited by 10
Tseng, H., Dholaria, B., Cranert, S. A., Richter, M., Marquez, K., Cho, B. S., Bacong, A., McArthur, K., Eskew, J. D., McCaigue, J., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65267-0 · Cited by 10
T cell immunotherapy for solid tumors: limitations, progress, and future prospects
Wang, Y., Zhang, B., Wang, Y., Tan, Y., Hu, X., Che, X., & Feng, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1755751 · Cited by 11
Update on the current and future use of CAR‐T to treat multiple myeloma
Gahvari, Z. J., Brunner, M., Schmidt, T. M., & Callander, N. S. (2023) · European Journal Of Haematology · doi:10.1111/ejh.14145 · Cited by 9
Grégoire, C., de Oliveira, B. C., Caimi, P. F., Caers, J., & Melenhorst, J. J. (2024) · British Journal of Haematology · doi:10.1111/bjh.19751 · Cited by 12
John, L., Sauer, S., Hegenbart, U., Dreger, P., Hundemer, M., Müller‐Tidow, C., Schmitt, A., Schmitt, M. W., Raab, M. S., & Schönland, S. O. (2023) · Transplantation and Cellular Therapy · doi:10.1016/j.jtct.2023.06.010 · Cited by 9
Integrating Immune Therapies for the Treatment of Multiple Myeloma.
Mikkilineni, L., & Sidana, S. (2023) · The Journal of the National Comprehensive Cancer Network · doi:10.6004/jnccn.2023.7100 · Cited by 7
Self-citationOverexpression of an Engineered SERPINB9 Enhances Allogeneic T-cell Persistence and Efficacy
Teo, P. Y., Jung, Y., Quach, D. H., Koh, J., Ong, R., Goh, A. X., Tan, A. S. M., Ng, C. H., Seh, C. C., Tan, K. W., et al. (2024) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-23-1001 · Cited by 8
Allogeneic and other innovative chimeric antigen receptor platforms
Jallouk, A. P., Sengsayadeth, S. M., Savani, B. N., Dholaria, B., & Oluwole, O. O. (2024) · Clinical Hematology International · doi:10.46989/001c.121404 · Cited by 8
Self-citationXu, Y., Zhang, X., Xin, D., Zhang, J., Wang, L., Fan, Y., Chen, B., Lei, W., Qiu, X., Jiang, H., et al. (2024) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-24-0051 · Cited by 8
Alloreactive-free CAR-VST therapy: a step forward in long-term tumor control in viral context
Wang, V., Savoldo, B., Guimaraes, J.-A., Dotti, G., Reppel, L., & Bensoussan, D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1527648 · Cited by 8
Expanding Immunotherapy Beyond CAR T Cells: Engineering Diverse Immune Cells to Target Solid Tumors
Andreou, T., Neophytou, C., Mpekris, F., & Stylianopoulos, T. (2025) · Cancers · doi:10.3390/cancers17172917 · Cited by 8
Filioglou, D., Husnain, M., Khurana, S., Simpson, R. J., & Katsanis, E. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1329850 · Cited by 8
Cellular Therapies for Multiple Myeloma: Engineering Hope
Vera-Cruz, S., Culubret, M., Konetzki, V., Alb, M., Friedel, S. R., Hudecek, M., Einsele, H., Danhof, S., & Scheller, L. (2024) · Cancers · doi:10.3390/cancers16223867 · Cited by 9
Human pluripotent stem cell-derived innate and adaptive immune cells for cancer immunotherapy
Shah, Z., Tian, L., Caligiuri, M. A., Kaufman, D. S., & Yu, J. (2026) · Cell stem cell · doi:10.1016/j.stem.2025.12.017 · Cited by 7
Stealth designs to overcome allorejection in engineered cell therapy
Li, Y.-R., Chen, Y., & Yang, L. (2026) · Trends in Immunology · doi:10.1016/j.it.2026.02.008 · Cited by 9
THE ROLE OF CAR T-CELL THERAPY IN THE ERA OF BISPECIFIC ANTIBODIES
Nath, K. D., Mailankody, S., & Usmani, S. Z. (2023) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2023.05.011 · Cited by 8
Self-citationHuang, H.-Y., Chen, Y., Li, Y., Zheng, X., Shu, L., Tian, L., Lin, H., & Yang, L. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e33001 · Cited by 7
Are we there yet? CAR ‐T therapy in multiple myeloma
Mirvis, E., & Benjamin, R. (2024) · British Journal of Haematology · doi:10.1111/bjh.19896 · Cited by 8
Current Main Topics in Multiple Myeloma
Morè, S., Corvatta, L., Manieri, V. M., Olivieri, A., & Offidani, M. (2023) · Cancers · doi:10.3390/cancers15082203 · Cited by 8
Midha, S., Hartley-Brown, M. A., Mo, C. C., Hossain, S., Nadeem, O., O’Donnell, E., Bianchi, G., Sperling, A. S., Laubach, J. P., & Richardson, P. G. G. (2023) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2023.2274420 · Cited by 7
Straßl, I., & Podar, K. (2024) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2024.2319672 · Cited by 8
Jo, T., Yoshihara, K., Ri, M., Tsukada, N., Mimura, N., Fujii, K., Fukushima, K., Fujiwara, S., Shimura, Y., Haraguchi, K., et al. (2024) · Blood Neoplasia · doi:10.1016/j.bneo.2024.100051 · Cited by 7
Li, R., Grosskopf, A. K., Joslyn, L. R., Stefanich, E. G., & Shivva, V. (2025) · The AAPS Journal · doi:10.1208/s12248-025-01017-w · Cited by 6
Rao, D., Wang, T., Fu, C., Luo, Y., Lu, J., Sun, Z., Yan, W., Liang, H., Xia, L., & Huang, W. (2025) · Cell Communication and Signaling · doi:10.1186/s12964-025-02465-9 · Cited by 7
Chen, J., Li, W., Wang, S., Li, J., Zhao, L., Ao, X., Wang, W., Zhu, L., Rao, H., Xu, S., et al. (2025) · Molecular Therapy · doi:10.1016/j.ymthe.2025.12.021 · Cited by 7
de Montes, A. L. R. G., & Spencer, L. M. (2023) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-23-0043 · Cited by 8
Guo, J., Wu, Q., Li, H., Liang, C., Dai, J., Zhang, S., Dai, C., Zhang, J., Wen, Y., & Yang, W. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1435934 · Cited by 6
CAR-based cell therapies for systemic lupus erythematosus
Wang, Y., Lu, L., Ye, S., & Fu, Q. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003406 · Cited by 6
Tun, A. M., Wang, Y., Maliske, S. M., Micallef, I. N., Inwards, D. J., Habermann, T. M., Porrata, L. F., Paludo, J., Villasboas, J. C., Rosenthal, A. C., et al. (2024) · Haematologica · doi:10.3324/haematol.2023.284704 · Cited by 6
Xu, C., Ma, H., Chen, J., Li, X., Wang, Z., Hu, B., Zhang, N., & Meng, F. (2023) · Thoracic Cancer · doi:10.1111/1759-7714.15180 · Cited by 5
Yeo, S. P., Kua, L. H., Tan, J. W., Lim, J. K., Wong, F. H., Santos, M. D., Poh, C. M., Goh, A. X., Koh, X. Y., Zhou, X., et al. (2024) · Cancer Research Communications · doi:10.1158/2767-9764.crc-23-0538 · Cited by 6
Zhou, S., Yang, Y., Jing, Y., & Zhu, X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1435635 · Cited by 5
Implementation of a CAR-T cell therapy program in India
Hotchandani, H., Sengar, M., Shetty, A., John, A., Karulkar, A., Kalra, D., Ravikumar, S., Jaiswal, A., Yadav, Y., Parkar, S., et al. (2025) · Expert Review of Anticancer Therapy · doi:10.1080/14737140.2025.2501744 · Cited by 5
CAR-T in cancer therapeutics and updates
Zhu, S. (2024) · Journal of the National Cancer Center · doi:10.1016/j.jncc.2024.01.001 · Cited by 5
Advances in research on factors affecting chimeric antigen receptor T‐cell efficacy
Zhou, D., Zhu, X., & Xiao, Y. (2024) · Cancer Medicine · doi:10.1002/cam4.7375 · Cited by 5
Advancement in “Off-the-Shelf” CAR T-Cell Therapy for Cancer Immunotherapy
Sheykhhasan, M., La’ah, A. S., Ahmadieh-Yazdi, A., Yang, P., Tanzadehpanah, H., Mahaki, H., Manoochehri, H., Poondla, N., Kalhor, N., & Al-Musawi, S. (2024) · Advances in medical diagnosis, treatment, and care (AMDTC) book series · doi:10.4018/979-8-3693-3976-3.ch002 · Cited by 5
Review of CAR T-Cell Therapy in Multiple Myeloma: A Canadian Perspective
Shih, S. C.-M., & Bhella, S. (2024) · Current Oncology · doi:10.3390/curroncol31070292 · Cited by 4
Yang, X., Wang, F., Yuan, X., Yang, B., Chen, J., Cheng, J., Liu, G., Tang, D., Xu, X., Wang, S., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1466443 · Cited by 4
Zadok, O. I. B., Simitsis, P., Jacobson, C. A., Nadeem, O., Frigault, M. J., Raje, N. S., Duffy, C., Costello, P., Cruz, J. D., Looka, A., et al. (2025) · British Journal of Haematology · doi:10.1111/bjh.70216 · Cited by 4
Self-citationCAR-T cell therapy: A therapeutic strategy for cancer treatment
Sharif, S., Sharma, U., & Yadav, A. K. (2025) · Seminars in Oncology · doi:10.1016/j.seminoncol.2025.152430 · Cited by 4
Chimeric Antigen Receptor T Cells in the Treatment of Multiple Myeloma
Hasanali, Z. S., Razzo, B. M., Susanibar-Adaniya, S. P., Garfall, A. L., Stadtmauer, E. A., & Cohen, A. D. (2023) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2023.12.004 · Cited by 5
Advanced strategies in improving the immunotherapeutic effect of CAR‐T cell therapy
Wang, M., Jia, L., Dai, X., & Zhang, X. (2024) · Molecular Oncology · doi:10.1002/1878-0261.13621 · Cited by 5
Rajeeve, S., Hoskote, A., & Mailankody, S. (2024) · Seminars in Hematology · doi:10.1053/j.seminhematol.2024.09.001 · Cited by 5
Self-citationArmstrong, A., Tang, Y., Mukherjee, N. Z., Zhang, N., & Huang, G. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1448201 · Cited by 4
Regulatory cell therapy for kidney transplantation and autoimmune kidney diseases
Ho, Q. Y., Hester, J., & Issa, F. (2024) · Pediatric Nephrology · doi:10.1007/s00467-024-06514-2 · Cited by 4
Moussa, D. A., Vazquez, M., Chable-Bessia, C., Roux-Portalez, V., Tamagnini, E., Pedotti, M., Simonelli, L., Ngo, G., Souchard, M., Lyonnais, S., et al. (2024) · Emerging Microbes & Infections · doi:10.1080/22221751.2024.2432345 · Cited by 4
Novel Approaches of Cellular Therapy in Multiple Myeloma: Focus on Chimeric Antigen Receptor T-Cells
Narra, R., Peshin, S., & Dhakal, B. (2024) · Acta Haematologica · doi:10.1159/000543265 · Cited by 5
Mini-TCRs: Truncated T cell receptors to generate T cells from induced pluripotent stem cells
Takayanagi, S., Wang, B., Hasegawa, S., Nishikawa, S., Fukumoto, K. I., Nakano, K., Chuganji, S., Kato, Y., Kamibayashi, S., Minagawa, A., et al. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.101109 · Cited by 4
Li, H., Huang, Q., & Zhang, Y. (2023) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2023.2291900 · Cited by 4
Management of relapsed refractory multiple myeloma: Evidence-based guide to community oncologists
Mushtaq, A. H., Cheema, A. Y., Ali, H. M., Shatnawi, Y., Ashruf, O. S., Ahmad, E. N., Lytvynova, O., Munir, M., Asif, M. A., Ahmad, M., et al. (2025) · Blood Reviews · doi:10.1016/j.blre.2025.101339 · Cited by 4
Self-citationReshaping multiple myeloma treatment: recent breakthroughs
Martino, E. A., Caserta, S., Vigna, E., Bruzzese, A., Mendicino, F., Alvaro, M. E., Labanca, C., Lucia, E., Olivito, V., Amodio, N., et al. (2025) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2025.2610373 · Cited by 4
Advancements and expanding applications of CAR-T cell therapy
Zhang, X., Liu, Z.-C., Luo, L.-J., Wu, Y., Cui, X.-G., & Chen, L. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1802718 · Cited by 3
Applications of genome editing technologies in the treatment of human diseases
Alshorman, J., Mehran, M. J., Tembo, K. M., Mostafavi, N., Bolideei, M., & Wang, Y. L. (2026) · Gene Therapy · doi:10.1038/s41434-026-00627-z · Cited by 3
CAR-T Therapy in Multiple Myeloma: Looking Beyond
Maiorana, G., Antolino, G., Verde, G. L., & Tafuri, A. (2024) · Hemato · doi:10.3390/hemato5020015 · Cited by 4
Allogeneic chimeric antigen receptors (CARs) as an “off-the-shelf” therapy in multiple myeloma
Carlson, S. G., Lin, T. L., & Larson, S. M. (2025) · Immunotherapy · doi:10.1080/1750743x.2025.2461987 · Cited by 4
Al-Janabi, I. I. (2024) · Al-Rafidain Journal of Medical Sciences · doi:10.54133/ajms.v6i2.726 · Cited by 3
Hu, X., White, K. A., Olroyd, A. G., Friera, A. M., Wang, C., Caruso, C. B., Connolly, A. J., Deuse, T., & Schrepfer, S. (2025) · iScience · doi:10.1016/j.isci.2025.112806 · Cited by 3
CAR-T cell therapy for patients with extramedullary multiple myeloma:Opportunities and challenges
Wang, Y., Hu, X., Du, J., & Liu, B. (2025) · European Journal of Cancer · doi:10.1016/j.ejca.2025.115374 · Cited by 2
Exposure to the immune system during bridging radiotherapy for Car-T cells
Loap, P., Decroocq, J., Birsen, R., Johnson, N., Bouscary, D., & Kirova, Y. (2025) · Cancer/Radiothérapie · doi:10.1016/j.canrad.2025.104595 · Cited by 2
Revolutions at the frontline of multiple myeloma treatment: lessons and challenges to finding a cure
Kort, J., Rivera, A., Senigarapu, S., & Driscoll, J. J. (2025) · Frontiers in Oncology · doi:10.3389/fonc.2025.1578529 · Cited by 2
Aoki, T., Kobayashi, M., Okoshi, M., Yamaguchi, M., Okura, H., Sasaki, S., Sasako, Y., Kira, S., Chang, Y., Yakushiji‐Kaminatsui, N., et al. (2026) · Stem Cell Research & Therapy · doi:10.1186/s13287-026-04994-7 · Cited by 2
Benda, M., Reimann, P., Willenbacher, W., Gunsilius, E., Weisel, K. C., Straßl, I., Krauth, M. T., Knop, S., Winder, T., & Steiner, N. (2026) · Annals of Hematology · doi:10.1007/s00277-026-07140-8 · Cited by 2
Current progress of CAR-T-cell therapy for patients with multiple myeloma
Nakashima, T., & Kagoya, Y. (2024) · International Journal of Hematology · doi:10.1007/s12185-024-03794-0 · Cited by 4
Özen, O., & Özen, M. İ. (2025) · Turkish Journal of Ophthalmology · doi:10.4274/tjo.galenos.2024.77783 · Cited by 3
Advancements in Multiple Myeloma Therapies: A Comprehensive Review by Disease Stage
Khatib, H. H. E., Abdulla, K., Nassar, L. K., Ellabban, M. G., & Kakarougkas, A. (2025) · Lymphatics · doi:10.3390/lymphatics3010002 · Cited by 2
Tang, S., Long, X., Li, F., Jiang, S., Fu, Y., & Liu, J. (2025) · Hematology · doi:10.1080/16078454.2025.2467499 · Cited by 2
Chari, A., Bal, S., Ailawadhi, S., Krishnan, A. Y., Patel, K. K., Berdeja, J. G., Garfall, A. L., Callander, N. S., Banerjee, R., Alsina, M., et al. (2025) · Clinical Lymphoma Myeloma & Leukemia · doi:10.1016/j.clml.2025.03.008 · Cited by 2
Aparicio, C., Queipo, M., Belver, M., Espeso, F., Serna-Pérez, J., Enríquez, L., Acebal, C., Martín‐Muñoz, Á., Valeri, A., Leivas, A., et al. (2025) · Cancers · doi:10.3390/cancers17193186 · Cited by 2
Embracing Myeloma Chimeric Antigen Receptor-T: From Scientific Design to Clinical Impact
Hosoya, H., Rodríguez‐Otero, P., Sidana, S., & Borrello, I. (2023) · American Society of Clinical Oncology Educational Book · doi:10.1200/edbk_389860 · Cited by 2
Self-citationBont, D. A. D., Straetemans, T., Sebestyén, Z., & Kuball, J. H. E. (2026) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2025-014199 · Cited by 2
Immunotherapy in multiple myeloma
Cantó, P. A., Arnao-Herráiz, M., & Comos, J. D. L. R. (2024) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2024.05.003 · Cited by 1
Lyu, N., Majd, Z., Fatima, B., Zeng, Z., Chen, H., & Abughosh, S. (2025) · Cancer Treatment and Research Communications · doi:10.1016/j.ctarc.2025.100921 · Cited by 3
CAR-T cell therapy for multiple myeloma: An update on the current state and future potential
Pophali, P. A., Rosenblatt, J. M., & Avigan, D. (2025) · Best Practice & Research Clinical Haematology · doi:10.1016/j.beha.2025.101659 · Cited by 1
How should we choose optimal salvage treatments following BCMA-directed CAR T-cell therapy?
Suresh, A., Pan, D., Lipof, J. J., Kumar, A. D., Arora, S., Sayre, P. H., Wolf, J. L., Martin, T. G., Chari, A., & Chung, A. (2025) · Immunotherapy · doi:10.1080/1750743x.2025.2571392 · Cited by 1
Identification and transformation of novel targets for immunotherapy in multiple myeloma
Wang, Y., Wang, Y., Ma, J., Jing, H., Liu, L., Qiu, L., & Hao, M. (2025) · Chinese Medical Journal · doi:10.1097/cm9.0000000000003869 · Cited by 1
Osborne, M., & Maher, J. F. (2025) · Biology · doi:10.3390/biology14121790 · Cited by 1
Biard, L., Lévy, V., Chevret, S., Künkele, A., Grunwald, S., Aiuti, A., Møller, B. K., Debets, R., Mielke, S., Eldere, J. V., et al. (2025) · Molecular Therapy Advances · doi:10.1016/j.omta.2025.201651 · Cited by 1
Nianias, A., Katsarou, A., Prins, H. J., Shahrabi, A., van Velzen, C., Henneman, L., Ruiter, R. W. J., Mutis, T., Groen, R. W. J., & Themeli, M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1757174 · Cited by 1
Yasui, H., Doki, N., Yan, W., Imai, K., & Ishida, T. (2026) · Cells · doi:10.3390/cells15040380 · Cited by 2
Graft-versus-host disease after chimeric antigen receptor T-cell therapy
Tan, B. R., & Wang, S. S. Y. (2026) · Blood Immunology & Cellular Therapy · doi:10.1016/j.bict.2026.100047 · Cited by 1
Wu, J., Li, D., Mei, H., & Hu, Y. (2026) · Biochemical Pharmacology · doi:10.1016/j.bcp.2026.117949 · Cited by 1
Metadata
- Authors
- Mailankody, S., Matous, J. V., Chhabra, S., Liedtke, M., Sidana, S., Oluwole, O. O., Malik, S., Nath, R., Anwer, F., Cruz, J. C., Htut, M., Karski, E. E., Lovelace, W., Dillon, M., Butz, E., Ying, W., Balakumaran, A., & Kumar, S. K.
- Affiliations
- Memorial Sloan Kettering Cancer Center (US)
- Colorado Blood Cancer Institute (US)
- Medical College of Wisconsin (US)
- Stanford Medicine (US)
- Vanderbilt University Medical Center (US)
- St David's Medical Center (US)
- Banner MD Anderson Cancer Center (US)
- Cleveland Clinic (US)
- City Of Hope National Medical Center (US)
- Allogene Therapeutics (United States) (US)
- Mayo Clinic (US)
- Corresponding author
- Mailankody, Sham
- ORCID
- Venue
- Nature Medicine
- Published
- 2023-01-23
- Volume
- 29
- Issue
- 2
- Pages
- 422-429
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W4317802192
- Cited by
- 257
- References
- 31
- Citations by year
- 2026: 42 · 2025: 57 · 2024: 96 · 2023: 60
- FWCI
- 31.02
- Type
- journal article
- Language
- en
- Update notices
- correction (2023-03-17)
- Open access
- closed
- Licence
- Locations
- Nature Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (P30CA008748)
- Topics
- Health Sciences › Medicine › Oncology › CAR-T cell therapy research
- Health Sciences › Medicine › Hematology › Multiple Myeloma Research and Treatments
- Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
- Keywords
- allogeneic CAR T cells, BCMA, multiple myeloma, relapsed/refractory multiple myeloma, anti-CD52 antibody, lymphocyte depletion, graft-versus-host disease prophylaxis, cytokine release syndrome, neurotoxicity, safety and tolerability, response rate, duration of response
- MeSH terms
- Cyclophosphamide, Humans, Multiple Myeloma, T-Lymphocytes, Immunotherapy, Adoptive, Hematopoietic Stem Cell Transplantation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review