Thalamic subnetworks as units of function
Open accessAbstract
The thalamus engages in various functions including sensory processing, attention, decision making and memory. Classically, this diversity of function has been attributed to the nuclear organization of the thalamus, with each nucleus performing a well-defined function. Here, we highlight recent studies that used state-of-the-art expression profiling, which have revealed gene expression gradients at the single-cell level within and across thalamic nuclei. These gradients, combined with anatomical tracing and physiological analyses, point to previously unappreciated heterogeneity and redefine thalamic units of function on the basis of unique input-output connectivity patterns and gene expression. We propose that thalamic subnetworks, defined by the intersection of genetics, connectivity and computation, provide a more appropriate level of functional description; this notion is supported by behavioral phenotypes resulting from appropriately tailored perturbations. We provide several examples of thalamic subnetworks and suggest how this new perspective may both propel progress in basic neuroscience and reveal unique targets with therapeutic potential.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Subtype 4's thalamic targeting likely participates in the transmission and processing of sensory information to regulate attention, consciousness, and sensory perception.
“subtype 4 specifically targets the thalamus (Fig. 2C), likely participating in the transmission and processing of sensory information to regulate attention, consciousness, and sensory perception [32,33].”
From The Insular Cortex: An Interface Between Sensation, Emotion and Cognition (2024) · cites this paper as [33]
The Abstract (page unavailable) describes thalamic nuclei involved in sensory processing, and ‘Identification of thalamic subnetworks’ (page unavailable) links sensory-projecting thalamic reticular neurons with attentional states. The paper does not identify the citing authors’ subtype 4 or establish that its thalamic targeting regulates attention, consciousness, and sensory perception; the consciousness component is not addressed in the passages found. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Genome-wide atlas of gene expression in the adult mouse brain
Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature · doi:10.1038/nature05453 · Cited by 5,572 · see citing works
Molecular diversity and specializations among the cells of the adult mouse brain
Saunders, A., Macosko, E. Z., Wysoker, A., Goldman, M., Krienen, F. M., de Rivera, H., Bien, E., Baum, M., Bortolin, L., Wang, S., et al. (2018) · Cell · doi:10.1016/j.cell.2018.07.028 · Cited by 1,847 · see citing works
Swanson, L. W., & Hartman, B. K. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901630406 · Cited by 1,479 · see citing works
Integrative single-cell analysis
Stuart, T., & Satija, R. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0093-7 · Cited by 1,460 · see citing works
Electrophysiological properties of guinea‐pig thalamic neurones: an in vitro study.
Jahnsen, H., & Llinás, R. R. (1984) · Journal of Physiology · doi:10.1113/jphysiol.1984.sp015153 · Cited by 1,213 · see citing works
Jones, E. G. (1985) · Springer eBooks · doi:10.1007/978-1-4615-1749-8 · Cited by 1,164 · see citing works
Lindvall, O., & Björklund, A. (1974) · PubMed · Cited by 1,136 · see citing works
Immunohistochemical evidence for the existence of adrenaline neurons in the rat brain
Ho¨kfelt, T., Fuxé, K., Goldstein, M., & Johansson, O. (1974) · Brain Research · doi:10.1016/0006-8993(74)90143-7 · Cited by 1,093 · see citing works
Jahnsen, H., & Llinas, R. H. (1984) · The Journal of Physiology · doi:10.1113/jphysiol.1984.sp015154 · Cited by 1,081 · see citing works
Neuronal cell-type classification: challenges, opportunities and the path forward
Zeng, H., & Sanes, J. R. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.85 · Cited by 841 · see citing works
Groenewegen, H. J. (1988) · Neuroscience · doi:10.1016/0306-4522(88)90339-9 · Cited by 732 · see citing works
The cortico-basal ganglia integrative network: The role of the thalamus
Haber, S. N., & Calzavara, R. (2008) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2008.09.013 · Cited by 721 · see citing works
Electrophysiology of mammalian thalamic neurones in vitro
Llinás, R., & Jahnsen, H. (1982) · Nature · doi:10.1038/297406a0 · Cited by 717 · see citing works
The thalamic reticular nucleus: structure, function and concept
Pinault, D. (2004) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.04.008 · Cited by 683 · see citing works
Exploring the Thalamus and Its Role in Cortical Function
Sherman, S. M., & Guillery, R. W. (2005) · The MIT Press eBooks · doi:10.7551/mitpress/2940.001.0001 · Cited by 672 · see citing works
Thalamic amplification of cortical connectivity sustains attentional control
Schmitt, L. I., Wimmer, R. D., Nakajima, M., Happ, M., Mofakham, S., & Halassa, M. M. (2017) · Nature · doi:10.1038/nature22073 · Cited by 663 · see citing works
Self-citationLongitudinal organization of the anterior neural plate and neural tube
Shimamura, K., Hartigan-O’Connor, D. J., Martı́nez, S., Puelles, L., & Rubenstein, J. L. R. (1995) · Development · doi:10.1242/dev.121.12.3923 · Cited by 654 · see citing works
Thalamic Relay Functions and Their Role in Corticocortical Communication
Guillery, R. W., & Sherman, S. M. (2002) · Neuron · doi:10.1016/s0896-6273(01)00582-7 · Cited by 637 · see citing works
Fode, C., Ma, Q., Casarosa, S., Ang, S.-L., Anderson, D. J., & Guillemot, F. (2000) · Genes & Development · doi:10.1101/gad.14.1.67 · Cited by 624 · see citing works
Dreher, B., Fukada, Y., & Rodieck, R. W. (1976) · The Journal of Physiology · doi:10.1113/jphysiol.1976.sp011429 · Cited by 548 · see citing works
Giguere, M., & Goldman-Rakic, P. S. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902770204 · Cited by 529 · see citing works
The paraventricular thalamus controls a central amygdala fear circuit
Penzo, M. A., Robert, V., Tucciarone, J., De Bundel, D., Wang, M., Van Aelst, L., Darvas, M., Parada, L. F., Palmiter, R. D., He, M., et al. (2015) · Nature · doi:10.1038/nature13978 · Cited by 506 · see citing works
Viewpoint: the core and matrix of thalamic organization
Jones, E. G. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00581-2 · Cited by 504 · see citing works
A study of Golgi preparations from the dorsal lateral geniculate nucleus of the adult cat
Guillery, R. W. (1966) · The Journal of Comparative Neurology · doi:10.1002/cne.901280104 · Cited by 447 · see citing works
Russchen, F. T., Amaral, D. G., & Price, J. L. (1987) · Journal of Comparative Neurology · doi:10.1002/cne.902560202 · Cited by 416 · see citing works
A thalamic input to the nucleus accumbens mediates opiate dependence
Zhu, Y., Wienecke, C. F. R., Nachtrab, G. T., & Chen, X. (2016) · Nature · doi:10.1038/nature16954 · Cited by 386 · see citing works
Innovations present in the primate interneuron repertoire
Krienen, F. M., Goldman, M., Zhang, Q., C. H. del Rosario, R., Florio, M., Machold, R., Saunders, A., Levandowski, K., Zaniewski, H., Schuman, B., et al. (2020) · Nature · doi:10.1038/s41586-020-2781-z · Cited by 381 · see citing works
Self-citationInnovations in Primate Interneuron Repertoire
Krienen, F. M., Goldman, M., Zhang, Q., del Rosario, R., Florio, M., Machold, R., Saunders, A., Levandowski, K., Zaniewski, H., Schuman, B., et al. (2019) · doi:10.1101/709501 · Cited by 372 · see citing works
Self-citationThe paraventricular thalamus is a critical thalamic area for wakefulness
Ren, S., Wang, Y., Yue, F., Cheng, X., Dang, R., Qiao, Q., Sun, X., Li, X., Jiang, Q., Yao, J., et al. (2018) · Science · doi:10.1126/science.aat2512 · Cited by 366 · see citing works
Sadikot, A. F., Parent, A., & François, C. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903150203 · Cited by 351 · see citing works
The axonal arborizations of lateral geniculate neurons in the striate cortex of the cat
Ferster, D., & Levy, S. (1978) · The Journal of Comparative Neurology · doi:10.1002/cne.901820510 · Cited by 336 · see citing works
Alzheimer's disease affects limbic nuclei of the thalamus
Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00305867 · Cited by 328 · see citing works
Saalmann, Y. B. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00083 · Cited by 323 · see citing works
Thalamocortical Circuit Motifs: A General Framework
Halassa, M. M., & Sherman, S. M. (2019) · Neuron · doi:10.1016/j.neuron.2019.06.005 · Cited by 322 · see citing works
Self-citationOrganization of visual inputs to interneurons of lateral geniculate nucleus of the cat
Dubin, M. W., & Cleland, B. G. (1977) · Journal of Neurophysiology · doi:10.1152/jn.1977.40.2.410 · Cited by 321 · see citing works
Szent�gothai, J., H�mori, J., & T�mb�l, T. (1966) · Experimental Brain Research · doi:10.1007/bf00234775 · Cited by 317 · see citing works
A dedicated circuit links direction-selective retinal ganglion cells to the primary visual cortex
Cruz‐Martín, A., El-Danaf, R. N., Osakada, F., Sriram, B., Dhande, O. S., Nguyen, P. L., Callaway, E. M., Ghosh, A., & Huberman, A. D. (2014) · Nature · doi:10.1038/nature12989 · Cited by 312 · see citing works
State-dependent architecture of thalamic reticular subnetworks
Halassa, M. M., Chen, Z., Wimmer, R. D., Brunetti, P. M., Zhao, S., Zikopoulos, B., Wang, F., Brown, E. N., & Wilson, M. A. (2014) · Cell · doi:10.1016/j.cell.2014.06.025 · Cited by 309 · see citing works
Self-citationThe anterior thalamus provides a subcortical circuit supporting memory and spatial navigation
Jankowski, M. M., Rönnqvist, K. C., Tsanov, M., Vann, S. D., Wright, N. F., Erichsen, J. T., Aggleton, J. P., & O’Mara, S. M. (2013) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2013.00045 · Cited by 304 · see citing works
Thalamic regulation of switching between cortical representations enables cognitive flexibility
Rikhye, R. V., Gilra, A., & Halassa, M. M. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0269-z · Cited by 302 · see citing works
Self-citationSynaptic organization in the lateral geniculate nucleus of the monkey
Colonnier, M., & Guillery, R. W. (1964) · Cell and Tissue Research · doi:10.1007/bf00339284 · Cited by 291 · see citing works
DLX-1, DLX-2, and DLX-5 expression define distinct stages of basal forebrain differentiation
Eisenstat, D. D., Liu, J. K., Mione, M., Zhong, W., Yu, G. K., Anderson, S. A., Ghattas, I. R., Puelles, L., & Rubenstein, J. L. R. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19991115)414:2 · Cited by 286 · see citing works
Kim, I.-J., Zhang, Y., Meister, M., & Sanes, J. R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4779-09.2010 · Cited by 282 · see citing works
Self-citationEmerging views of corticothalamic function
Briggs, F., & Usrey, W. M. (2008) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2008.09.002 · Cited by 268 · see citing works
Ohara, P. T., Lieberman, A. R., Hunt, S. P., & Jy, W. (1983) · Neuroscience · doi:10.1016/0306-4522(83)90060-x · Cited by 267 · see citing works
Li, S., & Kirouac, G. J. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21502 · Cited by 261 · see citing works
Yen, C., Conley, M., Hendry, S., & Jones, E. G. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-08-02254.1985 · Cited by 258 · see citing works
Heterogeneity within classical cell types is the rule: lessons from hippocampal pyramidal neurons
Cembrowski, M. S., & Spruston, N. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0125-5 · Cited by 258 · see citing works
Subnucleus-specific loss of neurons in medial thalamus of schizophrenics
Popken, G. J., Bunney, W. E., Potkin, S. G., & Jones, E. G. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.150243397 · Cited by 251 · see citing works
Early Exploration of the Visual Cortex
Hubel, D. H., & Wiesel, T. N. (1998) · Neuron · doi:10.1016/s0896-6273(00)80984-8 · Cited by 250 · see citing works
Anatomical demonstration of the suprachiasmatic nucleus-pineal pathway
Teclemariam‐Mesbah, R., Horst, G. J. T., Postema, F., Wortel, J., & Buijs, R. M. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990405)406:2 · Cited by 250 · see citing works
Henderson, J. M. (2000) · Brain · doi:10.1093/brain/123.7.1410 · Cited by 244 · see citing works
Thalamic control of functional cortical connectivity
Nakajima, M., & Halassa, M. M. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.04.001 · Cited by 232 · see citing works
Self-citationLi, S., & Kirouac, G. J. (2011) · Brain Structure and Function · doi:10.1007/s00429-011-0360-7 · Cited by 230 · see citing works
Clemente-Perez, A., Makinson, S. R., Higashikubo, B. T., Brovarney, S., Cho, F. S., Urry, A., Holden, S. S., Wimer, M., Dávid, C., Fenno, L. E., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.05.044 · Cited by 218 · see citing works
Dynamic salience processing in paraventricular thalamus gates associative learning
Zhu, Y., Nachtrab, G. T., Keyes, P. C., Allen, W. E., Luo, L., & Chen, X. (2018) · Science · doi:10.1126/science.aat0481 · Cited by 217 · see citing works
Multimodal gradients across mouse cortex
Fulcher, B., Murray, J. D., Zerbi, V., & Wang, X. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1814144116 · Cited by 217 · see citing works
The role of the thalamus in motor control
Sommer, M. A. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.10.014 · Cited by 214 · see citing works
Distinct subnetworks of the thalamic reticular nucleus
Li, Y., López-Huerta, V. G., Adiconis, X., Levandowski, K. M., Choi, S., Simmons, S., Arias-García, M. A., Guo, B., Yao, A. Y., Blosser, T. R., et al. (2020) · Nature · doi:10.1038/s41586-020-2504-5 · Cited by 208 · see citing works
Self-citationPinault, D., & Desch�nes, M. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19980209)391:2 · Cited by 199 · see citing works
Unveiling the diversity of thalamocortical neuron subtypes
Clascá, F., Rubio‐Garrido, P., & Jabaudon, D. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08033.x · Cited by 196 · see citing works
A repeated molecular architecture across thalamic pathways
Phillips, J. W., Schulmann, A., Hara, E., Winnubst, J., Liu, C., Valakh, V., Wang, L., Shields, B. C., Korff, W. L., Chandrashekar, J. V., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0483-3 · Cited by 191 · see citing works
Gao, C., Leng, Y., Ma, J., Rooke, V., Rodriguez-Gonzalez, S., Ramakrishnan, C., Deisseroth, K. A., & Penzo, M. A. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0572-3 · Cited by 180 · see citing works
Anterior-Posterior Direction Opponency in the Superficial Mouse Lateral Geniculate Nucleus
Marshel, J. H., Kaye, A. P., Nauhaus, I., & Callaway, E. M. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.021 · Cited by 178 · see citing works
Thalamic Regulation of Sucrose Seeking during Unexpected Reward Omission
Monte, F. H. D., Minier-Toribio, A. M., Quiñones-Laracuente, K., Medina-Colón, E. M., & Quirk, G. J. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.036 · Cited by 178 · see citing works
Féger, J., Bevan, M. D., & Crossman, A. R. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90208-9 · Cited by 176 · see citing works
Wamsley, J. K., Zarbin, M. A., Birdsall, N. J. M., & Kuhar, M. J. (1980) · Brain Research · doi:10.1016/0006-8993(80)91089-6 · Cited by 176 · see citing works
Bartlett, E. L., & Smith, P. H. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.5.1999 · Cited by 176 · see citing works
Nakagawa, Y., & O’Leary, D. D. M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02711.2001 · Cited by 173 · see citing works
Pape, H., & McCormick, D. A. (1995) · Neuroscience · doi:10.1016/0306-4522(95)00205-w · Cited by 172 · see citing works
Grubb, M. S., & Thompson, I. D. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00699.2003 · Cited by 169 · see citing works
Distinct Cortical-Thalamic-Striatal Circuits through the Parafascicular Nucleus
Mandelbaum, G., Taranda, J., Haynes, T. M., Hochbaum, D. R., Huang, K. W., Hyun, M., Venkataraju, K. U., Straub, C., Wang, W., Robertson, K., et al. (2019) · Neuron · doi:10.1016/j.neuron.2019.02.035 · Cited by 168 · see citing works
Visual Functions of the Thalamus
Usrey, W. M., & Alitto, H. J. (2015) · Annual Review of Vision Science · doi:10.1146/annurev-vision-082114-035920 · Cited by 164 · see citing works
Rompani, S. B., Müllner, F. E., Wanner, A. A., Zhang, C., Roth, C. N., Yonehara, K., & Roska, B. (2017) · Neuron · doi:10.1016/j.neuron.2017.01.028 · Cited by 156 · see citing works
Krahe, T. E., El-Danaf, R. N., Dilger, E. K., Henderson, S. C., & Guido, W. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4370-11.2011 · Cited by 144 · see citing works
Dong, X., Li, S., & Kirouac, G. J. (2017) · Brain Structure and Function · doi:10.1007/s00429-017-1445-8 · Cited by 143 · see citing works
Brown, H. D., Baker, P. M., & Ragozzino, M. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2167-10.2010 · Cited by 142 · see citing works
Spreafico, R., Battaglia, G. S., & Frassoni, C. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903040311 · Cited by 137 · see citing works
Woodward, N. D., Giraldo‐Chica, M., Rogers, B. P., & Cascio, C. J. (2016) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2016.09.002 · Cited by 136 · see citing works
Landisman, C. E., & Connors, B. W. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhm025 · Cited by 133 · see citing works
Deleuze, C., & Huguenard, J. R. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2333-06.2006 · Cited by 130 · see citing works
Kuramoto, E., Pan, S., Furuta, T., Tanaka, Y. R., Iwai, H., Yamanaka, A., Ohno, S. N., Kaneko, T., Goto, T., & Hioki, H. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.24054 · Cited by 130 · see citing works
Thalamic circuits for independent control of prefrontal signal and noise
Mukherjee, A., Lam, N. H., Wimmer, R. D., & Halassa, M. M. (2021) · Nature · doi:10.1038/s41586-021-04056-3 · Cited by 128 · see citing works
Self-citationA Spatiomolecular Map of the Striatum
Märtin, A., Calvigioni, D., Tzortzi, O., Fuzik, J., Wärnberg, E., & Meletis, K. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.11.096 · Cited by 127 · see citing works
Two dynamically distinct circuits drive inhibition in the sensory thalamus
Martinez-Garcia, R. I., Voelcker, B., Zaltsman, J. B., Patrick, S. L., Stevens, T. R., Connors, B. W., & Cruikshank, S. J. (2020) · Nature · doi:10.1038/s41586-020-2512-5 · Cited by 127 · see citing works
Glucose-responsive neurons of the paraventricular thalamus control sucrose-seeking behavior
Labouèbe, G., Boutrel, B., Tarussio, D., & Thorens, B. (2016) · Nature Neuroscience · doi:10.1038/nn.4331 · Cited by 125 · see citing works
Development, form, and function of the mouse visual thalamus
Guido, W. (2018) · Journal of Neurophysiology · doi:10.1152/jn.00651.2017 · Cited by 123 · see citing works
Functional Diversity of Thalamic Reticular Subnetworks
Crabtree, J. W. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00041 · Cited by 122 · see citing works
Core and matrix thalamic sub-populations relate to spatio-temporal cortical connectivity gradients
Müller, E. J., Munn, B., Hearne, L. J., Smith, J. B., Fulcher, B., Arnatkevičiūtė, A., Lurie, D. J., Cocchi, L., & Shine, J. M. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117224 · Cited by 117 · see citing works
Functional organization of the thalamic input to the thalamic reticular nucleus
Lam, Y.-W., & Sherman, S. M. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3073-10.2011 · Cited by 114 · see citing works
Abramson, B. P., & Chalupa, L. M. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90125-3 · Cited by 110 · see citing works
Kromer, L. F., & Moore, R. Y. (1980) · Neuroscience · doi:10.1016/0306-4522(80)90102-5 · Cited by 103 · see citing works
Parent, A., & Butcher, L. L. (1976) · The Journal of Comparative Neurology · doi:10.1002/cne.901700206 · Cited by 103 · see citing works
Expression of regulatory genes during differentiation of thalamic nuclei in mouse and monkey
Jones, E. G., & Rubenstein, J. L. R. (2004) · The Journal of Comparative Neurology · doi:10.1002/cne.20234 · Cited by 88 · see citing works
Heterogeneity of firing properties among rat thalamic reticular nucleus neurons
Lee, S.-H., Govindaiah, G., & Cox, C. L. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.134254 · Cited by 82 · see citing works
Roy, D. S., Zhang, Y., Aida, T., Choi, S., Chen, Q., Hou, Y., Lea, N. E., Skaggs, K. M., Quay, J., Liew, M., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.06.005 · Cited by 79 · see citing works
Self-citationTwo types of short axon (Golgi 2nd) interneurons in the specific thalamic nuclei.
Tömböl, T. (1969) · PubMed · Cited by 78 · see citing works
Chapter 27 Thalamic organization and function after Cajal
Jones, E. G. (2002) · Progress in brain research · doi:10.1016/s0079-6123(02)36029-1 · Cited by 76 · see citing works
Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala
O’Leary, T. P., Sullivan, K. E., Wang, L., Clements, J., Lemire, A. L., & Cembrowski, M. S. (2020) · eLife · doi:10.7554/elife.59003 · Cited by 75 · see citing works
Wilson, M. T., & Snow, D. M. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000828)424:3 · Cited by 72 · see citing works
A novel cortico-intrathalamic circuit for flight behavior
Dong, P., Wang, H., Shen, X., Jiang, P., Zhu, X., Li, Y., Gao, J., Lin, S., Huang, Y., He, X., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0391-6 · Cited by 71 · see citing works
Kalish, B. T., Cheadle, L., Hrvatin, S., Nagy, M. A., Rivera, S. A., Crow, M., Gillis, J. A., Kirchner, R. D., & Greenberg, M. E. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1717871115 · Cited by 68 · see citing works
Molecular anatomy of the thalamic complex and the underlying transcription factors
Nagalski, A., Puelles, L., Dąbrowski, M., Węgierski, T., Kuźnicki, J., & Wisniewska, M. B. (2015) · Brain Structure and Function · doi:10.1007/s00429-015-1052-5 · Cited by 64 · see citing works
Watson, G. D. R., Hughes, R. N., Petter, E. A., Fallon, I. P., Kim, N., Severino, F. P. U., & Yin, H. H. (2021) · Science Advances · doi:10.1126/sciadv.abe9192 · Cited by 64 · see citing works
Jones, E. G. (1983) · The Journal of Comparative Neurology · doi:10.1002/cne.902150102 · Cited by 61 · see citing works
Dual midbrain and forebrain origins of thalamic inhibitory interneurons
Jager, P., Moore, G., Calpin, P., Durmishi, X., Salgarella, I., Menage, L., Kita, Y., Wang, Y., Kim, D. W., Blackshaw, S., et al. (2021) · eLife · doi:10.7554/elife.59272 · Cited by 61 · see citing works
Matzeu, A., Kerr, T. M., Weiss, F., & Martin‐Fardon, R. (2016) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.116.235945 · Cited by 58 · see citing works
Nucleus- and cell-specific gene expression in monkey thalamus
Murray, K. D., Choudary, P. V., & Jones, E. G. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610742104 · Cited by 49 · see citing works
Morphology and membrane properties of neurones in the cat ventrobasal thalamus in Vitro
Turner, J. P., Anderson, C. M., Williams, S. R., & Crunelli, V. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.707ba.x · Cited by 48 · see citing works
Dopamine Modulates the Responsivity of Mediodorsal Thalamic Cells RecordedIn Vitro
Lavı́n, A., & Grace, A. A. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-24-10566.1998 · Cited by 47 · see citing works
Smith, P. H., Bartlett, E. L., & Kowalkowski, A. (2006) · The Journal of Comparative Neurology · doi:10.1002/cne.20913 · Cited by 45 · see citing works
Distinct Firing Properties of Higher Order Thalamic Relay Neurons
Li, J., Bickford, M. E., & Guido, W. (2003) · Journal of Neurophysiology · doi:10.1152/jn.01163.2002 · Cited by 44 · see citing works
Leist, M., Datunashvili, M., Kanyshkova, T. G., Zobeiri, M., Aissaoui, A., Cerina, M., Romanelli, M. N., Pape, H., & Budde, T. (2016) · Scientific Reports · doi:10.1038/srep24904 · Cited by 44 · see citing works
Sanchez-Vives, M. V., Bal, T., Kim, U., von Krosigk, M., & McCormick, D. A. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-19-05923.1996 · Cited by 40 · see citing works
Unified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons
Romanov, R. A., Alpár, A., Hökfelt, T. G. M., & Harkany, T. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050414 · Cited by 36 · see citing works
Tong, L., & Spear, P. D. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902460209 · Cited by 35 · see citing works
Kuroda, M., López‐Mascaraque, L., & Price, J. L. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903260106 · Cited by 33 · see citing works
Whilden, C. M., Chevée, M., An, S. Y., & Brown, S. P. (2021) · The Journal of Comparative Neurology · doi:10.1002/cne.25163 · Cited by 32 · see citing works
Beatty, J. A., Sylwestrak, E., & Cox, C. L. (2009) · Neuroscience · doi:10.1016/j.neuroscience.2009.04.043 · Cited by 31 · see citing works
Brunton, J., & Charpak, S. (1997) · Neuroscience · doi:10.1016/s0306-4522(97)00028-6 · Cited by 31 · see citing works
Aguilar, J., Morales-Botello, M. L., & Foffani, G. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06025.x · Cited by 29 · see citing works
Rompani, S. B., Müllner, F. E., Wanner, A., Zhang, C., Roth, C. N., Yonehara, K., & Roska, B. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.009 · Cited by 27 · see citing works
Reinforcement regulates timing variability in thalamus
Wang, J., Hosseini, E. A., Meirhaeghe, N., Akkad, A., & Jazayeri, M. (2020) · eLife · doi:10.7554/elife.55872 · Cited by 22 · see citing works
Ye, M., Hayar, A. M., & García‐Rill, E. (2009) · Journal of Neurophysiology · doi:10.1152/jn.91132.2008 · Cited by 18 · see citing works
Wang, M., Qu, Q., He, T., Li, M., Song, Z., Chen, F., Zhang, X., Xie, J., Geng, X., Yang, M., et al. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.05.031 · Cited by 16 · see citing works
Conley, M., Schmechel, D. E., & DIAMOND, I. T. (1991) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1991.tb00085.x · Cited by 11 · see citing works
Two contrasting mediodorsal thalamic circuits target the mouse medial prefrontal cortex
Lyuboslavsky, P. N., Ordemann, G. J., Kizimenko, A., & Brumback, A. C. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00456.2023 · Cited by 9 · see citing works
Lu, P.-L., Tsai, M., Jaw, F., & Yen, C. (2019) · The Journal of Physiological Sciences · doi:10.1007/s12576-018-00656-3 · Cited by 6 · see citing works
Two contrasting mediodorsal thalamic circuits target the medial prefrontal cortexPreprint
Lyuboslavsky, P. N., Kizimenko, A., & Brumback, A. C. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.20.427526 · Cited by 2 · see citing works
Huttenlocher (1997) · doi:10.1002/(sici)1096-9861(19971020)387:2
Day, H. E. W., Curran, E. J., Watson, S. J., & Akil, H. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19991011)413:1
Flagged first, then by citations
Research works printed but not linked: 3
- [3]Jones EG The Thalamus (Cambridge Univ. Press, 2007).
- [32]Lorente de No R Cerebral cortex: architecture, intracortical connections, motor projections (London: Oxford University Press, 1938).
- [84]Brunton J & Charpak S Heterogeneity of cell firing properties and opioid sensitivity in the thalamic reticular nucleus. Neuroscience 78, 303– 307 (1997). 9145788
Cited by
Sorted by citations
Roy, D. S., Park, Y.-G., Kim, M. E., Zhang, Y., Ogawa, S. K., DiNapoli, N., Gu, X., Cho, J. H., Choi, H., Kamentsky, L. D., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-29384-4 · Cited by 233 · see citing works
Self-citationThe Insular Cortex: An Interface Between Sensation, Emotion and Cognition
Zhang, R., Deng, H., & Xiao, X. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01211-4 · Cited by 158 · see citing works
The mediodorsal thalamus in executive control
Wolff, M., & Halassa, M. M. (2024) · Neuron · doi:10.1016/j.neuron.2024.01.002 · Cited by 96 · see citing works
Self-citationHuman high-order thalamic nuclei gate conscious perception through the thalamofrontal loop
Fang, Z., Dang, Y., Ping, A., Wang, C., Zhao, Q., Zhao, H., Xiaoli Li, A., & Zhang, M. (2025) · Science · doi:10.1126/science.adr3675 · Cited by 65 · see citing works
Generation of ventralized human thalamic organoids with thalamic reticular nucleus
Kiral, F. R., Çakır, B., Tanaka, Y., Kim, J., Yang, W. S., Wehbe, F., Kang, Y., Zhong, M., Sancer, G., Lee, S.-H., et al. (2023) · Cell stem cell · doi:10.1016/j.stem.2023.03.007 · Cited by 63 · see citing works
Zhao, J., Liu, C., Zhang, F., Zheng, Z., Luo, F., Xia, J., Wang, Y., Zhang, Z., Tang, J., Song, Z., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.111824 · Cited by 56 · see citing works
Sleep and vigilance states: Embracing spatiotemporal dynamics
Nir, Y., & de Lecea, L. (2023) · Neuron · doi:10.1016/j.neuron.2023.04.012 · Cited by 51 · see citing works
Molecular and spatial profiling of the paraventricular nucleus of the thalamus
Gao, C., Gohel, C., Leng, Y., Ma, J., Goldman, D. A., Levine, A. J., & Penzo, M. A. (2023) · eLife · doi:10.7554/elife.81818 · Cited by 45 · see citing works
Shin, D. S., Kim, C. N., Ross, J. M., Hennick, K. M., Wu, S., Paranjape, N., Leonard, R., Wang, J. C., Keefe, M. G., Pavlovic, B. J., et al. (2024) · Cell stem cell · doi:10.1016/j.stem.2024.01.010 · Cited by 46 · see citing works
A neural signature for the subjective experience of threat anticipation under uncertainty
Liu, X., Jiao, G., Zhou, F., Kendrick, K. M., Yao, D., Gong, Q., Xiang, S., Jia, T., Zhang, X., Zhang, J., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45433-6 · Cited by 42 · see citing works
Anterior thalamic circuits crucial for working memory
Roy, D. S., Zhang, Y., Aida, T., Shen, C.-J., Skaggs, K. M., Hou, Y., Fleishman, M., Mosto, O., Weninger, A., & Feng, G. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2118712119 · Cited by 42 · see citing works
Self-citationLi, D., Li, Y., Zhu, Z.-Y., Zhang, F., Zhao, Q., Jiang, J.-H., Shen, B., Tang, Y., & Xu, G. (2025) · Neuron · doi:10.1016/j.neuron.2025.04.019 · Cited by 42 · see citing works
Proprioception: A New Era Set in Motion by Emerging Genetic and Bionic Strategies?
Marasco, P. D., & de Nooij, J. C. (2022) · Annual Review of Physiology · doi:10.1146/annurev-physiol-040122-081302 · Cited by 45 · see citing works
Exploring human brain development and disease using assembloids
Wu, S., & Nowakowski, T. J. (2025) · Neuron · doi:10.1016/j.neuron.2025.02.010 · Cited by 36 · see citing works
Yang, W. F. Z., Sparby, T., Wright, M., Kim, E., & Sacchet, M. D. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e31223 · Cited by 34 · see citing works
Thalamocortical architectures for flexible cognition and efficient learning
Scott, D. N., Mukherjee, A., Nassar, M. R., & Halassa, M. M. (2024) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2024.05.006 · Cited by 35 · see citing works
Self-citationA phylogenetically-conserved axis of thalamocortical connectivity in the human brain
Oldham, S., & Ball, G. (2023) · Nature Communications · doi:10.1038/s41467-023-41722-8 · Cited by 34 · see citing works
Shima, Y., Skibbe, H., Sasagawa, Y., Fujimori, N., Iwayama, Y., Isomura-Matoba, A., Yano, M., Ichikawa, T., Nikaido, I., Hattori, N., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113309 · Cited by 31 · see citing works
The thalamic reticular nucleus orchestrates social memory
Wang, F., Sun, H., Chen, M., Feng, B., Lu, Y., Lyu, M., Cui, D., Zhai, Y., Zhang, Y., Zhu, Y., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.04.013 · Cited by 28 · see citing works
Self-citationMukherjee, A., & Halassa, M. M. (2022) · The Neuroscientist · doi:10.1177/10738584221112861 · Cited by 25 · see citing works
Self-citationNeuronal diversity and stereotypy at multiple scales through whole brain morphometry
Liu, Y., Jiang, S., Li, Y., Zhao, S., Yun, Z., Zhao, Z.-H., Zhang, L., Wang, G., Chen, X., Manubens-Gil, L., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-54745-6 · Cited by 25 · see citing works
The Role of the Thalamus in Nociception: Important but Forgotten
Galdino, G. S., Veras, F. P., & dos Anjos‐Garcia, T. (2024) · Brain Sciences · doi:10.3390/brainsci14080741 · Cited by 20 · see citing works
Halliday, A. R., Vucic, S. N., Georges, B., LaRoche, M., Mendoza Pardo, M. A., Swiggard, L. O., McDonald, K., Olofsson, M., Menon, S. N., Francis, S. M., et al. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1474003 · Cited by 20 · see citing works
Thalamocortical Mechanisms Underlying Real and Imagined Acupuncture
Kong, Q., Saccà, V., Walker, K. L., Hodges, S., & Kong, J. (2023) · Biomedicines · doi:10.3390/biomedicines11071830 · Cited by 20 · see citing works
The Evolved Mind and Modern Education
Geary, D. C. (2024) · Cambridge University Press eBooks · doi:10.1017/9781009454858 · Cited by 18 · see citing works
Deng, J. F., Chen, L., Liu, C., Liu, M., Guo, G., Wei, J., Zhang, J., Fan, H.-T., Zheng, Z., Yan, P., et al. (2024) · Advanced Science · doi:10.1002/advs.202401855 · Cited by 18 · see citing works
Czekus, C., Steullet, P., López, A. O., Bozic, I., Rusterholz, T., Bandarabadi, M., Kim, Q., & Herrera, C. G. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01700-w · Cited by 17 · see citing works
Frustrative Nonreward: Behavior, Circuits, Neurochemistry, and Disorders
Papini, M. R., Green, T. A., Contreras, Y. M. M., Torres, C., Ogawa, M., & Li, Z. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1021-24.2024 · Cited by 18 · see citing works
A prefrontal thalamocortical readout for conflict-related executive dysfunction in schizophrenia
Huang, A., Wimmer, R. D., Lam, N. H., Wang, B., Suresh, S., Roeske, M. J., Pleger, B., Halassa, M. M., & Woodward, N. D. (2024) · Cell Reports Medicine · doi:10.1016/j.xcrm.2024.101802 · Cited by 18 · see citing works
Self-citationChibaatar, E., Watanabe, K., Okamoto, N., Orkhonselenge, N., Natsuyama, T., Hayakawa, G., Ikenouchi, A., Kakeda, S., & Yoshimura, R. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1151551 · Cited by 16 · see citing works
Zhang, Z., Huang, Y., Chen, X., Li, J., Yang, Y., Lv, L., Wang, J., Wang, M., Wang, Y., & Wang, Z. (2024) · Advanced Science · doi:10.1002/advs.202402718 · Cited by 14 · see citing works
Mediodorsal thalamus regulates task uncertainty to enable cognitive flexibility
Zhang, X., Mukherjee, A., Halassa, M. M., & Chen, Z. S. (2025) · Nature Communications · doi:10.1038/s41467-025-58011-1 · Cited by 17 · see citing works
Self-citationDai, L., Mai, J.-W., Deng, J., Chen, L., Fan, H.-T., Zhang, W.-L., Xin, W., Feng, X., Xu, T. S., & Luo, D. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106699 · Cited by 14 · see citing works
Whiteside, D. J., Street, D., Murley, A. G., Jones, P. S., Malpetti, M., Ghosh, B. C. P., Coyle-Gilchrist, I. T. S., Gerhard, A., Hu, M. T., Klein, J. C., et al. (2023) · Human Brain Mapping · doi:10.1002/hbm.26342 · Cited by 13 · see citing works
Yu, T., Zou, Y., Nie, H., Li, Y., Chen, J., Du, Y., Peng, H., & Luo, Q. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.11.074 · Cited by 13 · see citing works
Fredericksen, K. E., & Samuelsen, C. L. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0674-22.2022 · Cited by 14 · see citing works
Whole-brain Mapping of Inputs and Outputs of Specific Orbitofrontal Cortical Neurons in Mice
Zhang, Y., Zhang, W., Wang, L., Liu, D., Xie, T., Le, Z., Li, X., Gong, H., Xu, X., Xu, M., et al. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01229-8 · Cited by 12 · see citing works
Self-citationLiu, D., Xu, F.-X., Yu, Z., Huang, X., Zhu, Y.-B., Wang, L.-J., Wu, C., Zhang, X., Cao, J., & Li, J. (2025) · Journal of Clinical Investigation · doi:10.1172/jci191270 · Cited by 12 · see citing works
Distinct subnetworks of the mouse anterior thalamic nuclei
Hintiryan, H., Rudd, M., Nanda, S., Gutierrez, A. E., Lo, D., Boesen, T., Garcia, L., Sun, J., Estrada, C., Mun, H.-S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60774-6 · Cited by 11 · see citing works
Thalamic pathways mediating motor and non-motor symptoms in a Parkinson’s disease model
Xiao, B., & Tan, E. (2022) · Trends in Neurosciences · doi:10.1016/j.tins.2022.09.004 · Cited by 11 · see citing works
Mapping whole brain effects of infrared neural stimulation with positron emission tomography
Meneghetti, M., Gudmundsen, F., Jessen, N. S., Sui, K., Baun, C., Palner, M., & Markos, C. (2023) · Imaging Neuroscience · doi:10.1162/imag_a_00052 · Cited by 12 · see citing works
Non-homogenous axonal bouton distribution in whole-brain single-cell neuronal networks
Qian, P., Manubens-Gil, L., Jiang, S., & Peng, H. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.113871 · Cited by 8 · see citing works
Dissection of the long-range circuit of the mouse intermediate retrosplenial cortex
Li, Y., Ren, M., Liu, B., Jiang, T., Jia, X., Zhang, H., Gong, H., & Wang, X. (2025) · Communications Biology · doi:10.1038/s42003-025-07463-8 · Cited by 9 · see citing works
Shiraishi, H., Egawa, K., Murakami, K., Nakajima, M., Ueda, Y., Nakakubo, S., Narugami, M., Kimura, S., Goto, T., Hiramatsu, Y., et al. (2023) · Brain and Development · doi:10.1016/j.braindev.2023.08.007 · Cited by 9 · see citing works
Zhang, P., He, Z., Mao, Y., Sun, R., Qu, Y., Chen, L., Ma, P., Yin, S., Yin, T., & Zeng, F. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1001557 · Cited by 8 · see citing works
Structural network-specific effect of extreme capsule stimulation for drug-resistant focal epilepsy
Cheng, Y., Wang, D., Zhang, X., Jin, G., Wu, D., Wang, Q., Du, J., Qi, L., Xu, C., Qiao, Z., et al. (2025) · Brain · doi:10.1093/brain/awaf097 · Cited by 8 · see citing works
The unique role of the associative thalamus in cognitive processing
Wang, B., Li, S., Halassa, M. M., & Pleger, B. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111432 · Cited by 8 · see citing works
Self-citationDai, Y., Hu, J., Wang, Q., Qiao, J., Tian, Y., Li, C., Chen, J., Zhao, F., Li, X., Liu, C., et al. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70514 · Cited by 8 · see citing works
Zhou, W., Xie, X., Hu, J., Wang, M., Hu, X., Shi, L., Zhou, C., & Sun, X. (2023) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.28781 · Cited by 7 · see citing works
Perinatal development of structural thalamocortical connectivity
Oldham, S., Sina Mansour, L., & Ball, G. (2024) · Imaging Neuroscience · doi:10.1162/imag_a_00418 · Cited by 7 · see citing works
Deciphering consciousness: The role of corticothalamocortical interactions in general anesthesia
Zhou, Y., Huang, S., Zhang, T., Deng, D., Huang, L., & Chen, X. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107593 · Cited by 7 · see citing works
Mapping the pain pathway: The VPL–S1HL–ACC circuit's role in central post-stroke pain
Li, P., Lu, C., Wang, M., Mao, Y., Wang, X., Liu, Y., Zhang, J., & Zhao, S. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111406 · Cited by 7 · see citing works
Zheng, Y., Wang, P., Yao, C., Wang, J., Wang, J., & Xue, S. (2025) · Human Brain Mapping · doi:10.1002/hbm.70249 · Cited by 7 · see citing works
Learning Temporal Relationships Between Symbols with Laplace Neural Manifolds
Howard, M. W., Esfahani, Z. G., Le, B., & Sederberg, P. B. (2024) · Computational Brain & Behavior · doi:10.1007/s42113-024-00230-8 · Cited by 8 · see citing works
Haubrich, J., Vera, L. D., & Manahan‐Vaughan, D. (2025) · Scientific Reports · doi:10.1038/s41598-025-93263-3 · Cited by 7 · see citing works
Ma, L., Tao, Q., Dang, J., Sun, J., Niu, X., Zhang, M., Kang, Y., Wang, W., Cheng, J., & Zhang, Y. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1403604 · Cited by 6 · see citing works
Self-citationA parallel tonotopically arranged thalamocortical circuit for sound processing
Zhao, Z., Tang, X., Chen, Y., Tao, J., Polat, M., Yang, Z., Yang, L., Wang, M., Liang, S., Zhang, K., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.03.022 · Cited by 6 · see citing works
Self-citationLuo, S., Wang, Y., He, M., Wen, Q., Wang, S., Cao, J., & Chen, Q. (2025) · BMJ Mental Health · doi:10.1136/bmjment-2024-301142 · Cited by 6 · see citing works
Gustatory thalamic neurons mediate aversive behaviors
Cao, F., Park, S., Pauli, J. L., Seo, E. Y., Nguyen, A.-D., & Palmiter, R. D. (2025) · Nature Communications · doi:10.1038/s41467-025-63464-5 · Cited by 7 · see citing works
An opposing molecular gradient axis underlies primate cortical organization
Huang, Z. R., Yang, Q., Li, S., Zhu, X., Wang, H., Lin, J., Zhan, Y., Wu, Y. H., Wang, Z.-H., Majka, P., et al. (2026) · Science · doi:10.1126/science.aea2673 · Cited by 8 · see citing works
Functional connectivity alterations in the thalamus among patients with bronchial asthma
Wang, T., Huang, X., Dai, L., Zhan, K.-M., & Wang, J. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1378362 · Cited by 6 · see citing works
Campbell, P. W., Govindaiah, G., & Guido, W. (2024) · Neural Development · doi:10.1186/s13064-024-00183-5 · Cited by 6 · see citing works
Chen, Z., Cai, Y., Liu, Y., Liu, H., Wei, X., Lin, C., Liu, D., Xiao, L., & Rong, L. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1388213 · Cited by 6 · see citing works
Ventral posteromedial nucleus of the thalamus gates the spread of trigeminal neuropathic pain
Du, Y., Lin, S.-D., Wu, X., Xue, B.-Y., Ding, Y.-L., Zhang, J.-H., Tan, B., Lou, G., Hu, W., Chen, Z., et al. (2024) · The Journal of Headache and Pain · doi:10.1186/s10194-024-01849-5 · Cited by 7 · see citing works
Long‐range inputome of prefrontal GABAergic interneurons in the Alzheimer's disease mouse
Ren, M., Li, Y., Jiang, T., Liu, B., Li, X., Jia, X., Li, A., Luo, Q., Gong, H., & Li, X. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14552 · Cited by 6 · see citing works
Bordin, V., Pirastru, A., Bergsland, N., Cazzoli, M., Baselli, G., & Baglio, F. (2023) · NeuroImage · doi:10.1016/j.neuroimage.2023.120272 · Cited by 6 · see citing works
Yokoyama, H., Kaneko, N., Usuda, N., Kato, T., Khoo, H. M., Fukuma, R., Oshino, S., Tani, N., Kishima, H., Yanagisawa, T., et al. (2024) · APL Bioengineering · doi:10.1063/5.0226457 · Cited by 6 · see citing works
A neural signature for the subjective experience of threat anticipation under uncertaintyPreprint
Liu, X., Jiao, G., Zhou, F., Kendrick, K. M., Yao, D., Xiang, S., Jia, T., Zhang, X., Zhang, J., Feng, J., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.20.558716 · Cited by 6 · see citing works
The potential of laminar functional MRI in refining the understanding of epilepsy in humans
Aitken, F., Winston, J. S., O'Muircheartaigh, J., & Carmichael, D. W. (2025) · Brain : a journal of neurology · doi:10.1093/brain/awaf320 · Cited by 4 · see citing works
Acosta-Mejia, M. T., & Villalobos, N. (2023) · Diagnostics · doi:10.3390/diagnostics13142394 · Cited by 5 · see citing works
A multimodal characterization of low-dimensional thalamocortical structural connectivity patterns
John, A., Hettwer, M. D., Schaare, H. L., Saberi, A., Bayrak, Ş., Wan, B., Royer, J., Bernhardt, B. C., & Valk, S. L. (2025) · Communications Biology · doi:10.1038/s42003-025-07528-8 · Cited by 8 · see citing works
Gao, W., Zhang, K., Jiao, Q., Su, L., Cui, D., Lu, S., & Yang, R. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-07018-5 · Cited by 5 · see citing works
Anterior thalamic nuclei: A critical substrate for non‐spatial paired‐associate memory in rats
Hamilton, J. J., & Dalrymple‐Alford, J. C. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15802 · Cited by 5 · see citing works
Naik, A. A., Ma, X., Munyeshyaka, M., Leibenluft, E., & Li, Z. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.28.530477 · Cited by 5 · see citing works
Howell, A. M., Warrington, S., Fonteneau, C., Cho, Y., Sotiropoulos, S. N., Murray, J. D., & Anticevic, A. (2024) · eLife · doi:10.7554/elife.95018 · Cited by 5 · see citing works
Kalchev, E. (2023) · Journal of medical imaging and radiation sciences · doi:10.1016/j.jmir.2023.08.012 · Cited by 4 · see citing works
Zhou, S., Kuang, Q., Huang, H.-Q., She, S., Zheng, Y., & Li, X. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06535-7 · Cited by 4 · see citing works
Developing algorithmic psychiatry via multi-level spanning computational models
Halassa, M. M., Frank, M. J., Garety, P. A., Öngür, D., Airan, R. D., Sanacora, G., Dzirasa, K., Suresh, S., Fitzpatrick, S. M., & Rothman, D. L. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102094 · Cited by 6 · see citing works
Self-citationKelemen, K., Orbán-Kis, K., Szentes, Á., Nagy, Z., Kelemen, H., Fehér, A., Bába, L.-I., Gáll, Z., Horváth, E., Katona, I., et al. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26104906 · Cited by 4 · see citing works
Ye, J., Xu, C., Guo, H., Huang, W., Xie, G., & Liang, J. (2025) · Scientific Reports · doi:10.1038/s41598-025-00431-6 · Cited by 3 · see citing works
Xie, B., Ni, H., Yao, J., Xu, Z., Bian, S., Wang, H., Zhu, K., Wu, X., Song, P., Wu, Y., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-00909-4 · Cited by 3 · see citing works
Corticothalamic communication for action coordination in a skilled motor behavior
Li, Y., An, X., Mulcahey, P. J., Qian, Y., Xu, X. H., Zhao, S., Mohan, H., Suryanarayana, S. M., Bachschmid-Romano, L., Brunel, N., et al. (2026) · Nature Neuroscience · doi:10.1038/s41593-025-02195-8 · Cited by 3 · see citing works
Brihmat, N., Saleh, S., Zhang, F., Carnahan, J., Bayram, M. B., Yue, G. H., & Forrest, G. F. (2026) · Scientific Reports · doi:10.1038/s41598-026-36187-w · Cited by 3 · see citing works
Reevaluating thalamic contributions to pain: A translational framework for precision neuromodulation
Li, Z., Zhang, F., Ren, J., Lu, X., & Hu, L. (2026) · Physics of Life Reviews · doi:10.1016/j.plrev.2026.02.001 · Cited by 3 · see citing works
Yasuno, F., Kimura, Y., Nihashi, T., Minami, H., Minami, H., Takeda, A., Sakurai, T., & Kato, T. (2026) · International Psychogeriatrics · doi:10.1016/j.inpsyc.2026.100199 · Cited by 3 · see citing works
Wu, J., Zhang, Q., Ma, M., Dong, Y., Sun, P.-F., Gao, M. J., Liu, P., & Wu, X. (2024) · NeuroToxicology · doi:10.1016/j.neuro.2024.07.002 · Cited by 3 · see citing works
Zhang, L., He, C., Liu, X., Fan, D., Haisan, Z., Hongxing, Z., & Xie, C. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70116 · Cited by 3 · see citing works
Roy, E. R., Wang, Q., Huang, K., Li, S., Fan, Y., Escobar, E., Atkins, C. L., Huang, S., Herrera, J. J., Li, W., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-12869-9 · Cited by 5 · see citing works
Sparse memory ensembles set brain-wide network states to sustain learned associations
Haubrich, J., Russo, G., & Manahan‐Vaughan, D. (2025) · iScience · doi:10.1016/j.isci.2025.113574 · Cited by 3 · see citing works
Nuclei and tracts in the thalamus of crocodiles
Pritz, M. B. (2024) · The Journal of Comparative Neurology · doi:10.1002/cne.25595 · Cited by 3 · see citing works
Preconfigured cortico-thalamic neural dynamics constrain movement-associated thalamic activity
González-Pereyra, P., Sánchez-Lobato, O., Martínez-Montalvo, M. G., Ortega-Romero, D. I., Pérez-Díaz, C. I., Merchant, H., Tellez, L. A., & Rueda-Orozco, P. (2024) · bioRxiv · doi:10.1038/s41467-024-54742-9 · Cited by 4 · see citing works
Govek, K. W., Chen, S., Sgourdou, P., Yao, Y., Woodhouse, S., Chen, T., Fuccillo, M. V., Epstein, D. J., & Cámara, P. G. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.18.481097 · Cited by 3 · see citing works
Howell, A. M., Warrington, S., Fonteneau, C., Cho, Y., Sotiropoulos, S. N., Murray, J. D., & Anticevic, A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.22.550168 · Cited by 4 · see citing works
Cortico-thalamic communication for action coordination in a skilled motor sequencePreprint
Li, Y., An, X., Mulcahey, P. J., Qian, Y., Xu, X. H., Zhao, S., Mohan, H., Suryanarayana, S. M., Bachschmid-Romano, L., Brunel, N., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.25.563871 · Cited by 3 · see citing works
Fang, Z., Dang, Y., Ping, A., Wang, C., Zhao, Q., Zhao, H., Xiaoli Li, A., & Zhang, M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.02.587714 · Cited by 3 · see citing works
Hierarchical sensory processing in zebrafish thalamocortical-like circuits
Trinh, A.-T., Ostenrath, A. M., del Castillo-Berges, I., Cachin, F., Koç, M., Kraus, S., Serneels, B., Kawakami, K., & Yaksi, E. (2026) · Science · doi:10.1126/science.aec2171 · Cited by 5 · see citing works
The Role of Layer 6 Corticothalamic Circuits in Vision: Plasticity, Sensory Processing, and Behavior
Katzner, S., Rose, T., Tchumatchenko, T., & Busse, L. (2025) · Annual Review of Vision Science · doi:10.1146/annurev-vision-101322-012348 · Cited by 2 · see citing works
Qin, M., Jin, X., Yang, Y., Gong, F., Wan, J., Wei, J., Sun, B., Li, X., & Hao, Y. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07171-1 · Cited by 2 · see citing works
Weyer, C., Sarisik, E., Tovar-Perdomo, S., Vetter, C. S., Dwyer, D. B., Antonucci, L. A., Lichtenstein, T., Kambeitz‐Ilankovic, L., Kambeitz, J. P., Ruhrmann, S., et al. (2026) · Biological Psychiatry · doi:10.1016/j.biopsych.2026.03.994 · Cited by 2 · see citing works
Thompson, S. J., Miao, Q., Sonig, A., & Noebels, J. L. (2026) · Neuron · doi:10.1016/j.neuron.2026.03.015 · Cited by 2 · see citing works
- Authors
- Roy, D. S., Zhang, Y., Halassa, M. M., & Feng, G.
- Affiliations
- Broad Institute (US)
- McGovern Institute for Brain Research (US)
- Corresponding author
- Roy, Dheeraj S.
- Feng, Guoping
- Venue
- Nature Neuroscience
- Published
- 2022-01-31
- Volume
- 25
- Issue
- 2
- Pages
- 140-153
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- PMC
- PMC9400132
- OpenAlex
- W4221072568
- Cited by
- 177
- References
- 129
- Citations by year
- 2026: 35 · 2025: 54 · 2024: 47 · 2023: 27 · 2022: 14
- FWCI
- 3.69
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc-sa)
- Funders
- National Institute of Mental Health (U01MH114819)
- National Institute of Neurological Disorders and Stroke (R01NS113245)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Single-cell and spatial transcriptomics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- thalamus, thalamic nuclei, behavioral phenotypes, therapeutic target
- MeSH terms
- Attention, Neural Pathways, Thalamic Nuclei, Thalamus
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
