A randomized, double-blind, placebo-controlled trial on the efficacy of ginger in the prevention of abdominal distention in post cesarean section patients
Open accessAbstract
The objective of the study was to evaluate the efficacy of ginger in the prevention of abdominal distention in post cesarean section patients. A randomized, double-blind, placebo controlled trial was conducted. One hundred and seventy-eight post cesarean section patients were either randomized to the study group receiving oral ginger capsules or to the placebo group receiving oral placebo capsules. The average age of the studied women was 32.3 years. The incidence of postoperative abdominal distention was not different between the ginger and the placebo groups (20.2% vs 29.2%, p = 0.328). The efficacy to relieve abdominal distention was superior in the ginger group than the placebo group (91% vs 65.2%, p < 0.001). With regards to quality of life, the number of patients who had the ability to eat was higher in the ginger group than in the placebo group (59.6% vs 43.8%, p = 0.035). There were no significant differences in time to first flatus, maternal satisfaction, and side effects. Ginger does not decrease the incidence of post cesarean section abdominal distention. But, ginger is more effective than the placebo in relieving the severity of abdominal distention on the fourth day after operation and improving the ability to eat.
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Previous studies have reported that ginger supplementation can improve constipation without causing diarrhea.
“Consistent with our findings, previous studies have reported that ginger supplementation can improve constipation without causing diarrhea [31, 32].”
From The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: a double-blind randomized placebo-controlled trial (2023) · cites this paper as [32]
The Introduction and Discussion say ginger can relieve constipation, and the Results report a shorter time to first defecation in the ginger group. But Table 3 records diarrhea in six ginger-group patients and three placebo-group patients; although overall side effects did not differ significantly, the paper does not establish that ginger improves constipation without causing diarrhea. (LLM, conf=0.87)
Experimental — accuracy not yet measuredAnother trial revealed that ginger consumption caused a significant reduction in time to first defecation after cesarean section in women.
“another trial revealed that ginger consumption caused a significant reduction in time to first defecation after cesarean section in women [32].”
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- Authors
- Tianthong, W., & Phupong, V.
- Affiliations
- Chulalongkorn University (TH)
- Corresponding author
- Phupong, Vorapong
- Venue
- Scientific Reports
- Published
- 2018-05-01
- Volume
- 8
- Issue
- 1
- Pages
- 6835-6835
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC5931585
- OpenAlex
- W2799825577
- Semantic Scholar
- 6aa7a867f77891db1ee4045d8d0c4471fa330270
- Cited by
- 18
- References
- 18
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 3 · 2022: 3 · 2021: 1 · 2020: 2 · 2019: 2
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, other-oa)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Chulalongkorn University
- Faculty of Medicine, Chulalongkorn University
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Ginger and Zingiberaceae research
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Keywords
- ginger, abdominal distension, post cesarean section, postoperative complications, quality of life, flatus, maternal satisfaction, herbal medicine
- MeSH terms
- Adult, Cesarean Section, Defecation, Double-Blind Method, Female, Gastrointestinal Motility, Humans, Phytotherapy, Plant Extracts, Postoperative Complications, Pregnancy, Quality of Life, Severity of Illness Index, Incidence, Chi-Square Distribution, Treatment Outcome, Statistics, Nonparametric, Zingiber officinale, Ileus
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